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Displaying drugs 551 - 575 of 3040 in total
Insulin detemir
Insulin detemir is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A2358, A2359, A2360, A44] Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta...
Approved
Matched Synonyms: … Insulin,detemir,human ... Insulin detemir recombinant …
Matched Description: … typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human ... [A2358, A2359, A2360, A44] Insulin detemir is produced using recombinant DNA technology in yeast cells …
Matched Description: … typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human ... [A2358, A2359, A2360, A44] Insulin detemir is produced using recombinant DNA technology in yeast cells …
Anakinra
Anakinra is a recombinant human interleukin-1 (IL-1) receptor antagonist (IL-1Ra) composed of 153 amino acid residues. Unlike native human IL-1Ra, anakinra has an additional methionine residue at the amino terminus. This drug binds to the IL-1 receptor, competing with and inhibiting the activity of IL-1 alpha and beta. Anakinra is...
Approved
Investigational
Matched Synonyms: … Interleukin-1 receptor antagonist anakinra …
Matched Description: … Anakinra is a recombinant human interleukin-1 (IL-1) receptor antagonist (IL-1Ra) composed of 153 amino ... Unlike native human IL-1Ra, anakinra has an additional methionine residue at the amino terminus. ... well as the treatment of neonatal-onset multisystem inflammatory disease (NOMID) and deficiency of interleukin …
Matched Categories: … Interleukin Inhibitors ... Interleukin-1 Receptor Antagonist …
Matched Description: … Anakinra is a recombinant human interleukin-1 (IL-1) receptor antagonist (IL-1Ra) composed of 153 amino ... Unlike native human IL-1Ra, anakinra has an additional methionine residue at the amino terminus. ... well as the treatment of neonatal-onset multisystem inflammatory disease (NOMID) and deficiency of interleukin …
Matched Categories: … Interleukin Inhibitors ... Interleukin-1 Receptor Antagonist …
Influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) recombinant hemagglutinin antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) recombinant hemagglutinin antigen …
Coagulation Factor IX (Recombinant)
Recombinant Coagulation Factor IX is a purified Factor IX glycoprotein produced by recombinant DNA technology. It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, and has structural and functional characteristics similar to those of endogenous factor IX. It is not...
Approved
Investigational
Matched Synonyms: … Coagulation factor IX recombinant human ... Recombinant factor IX ... Factor IX (Recombinant) …
Matched Name: … Coagulation Factor IX (Recombinant) …
Matched Description: … It is not derived from human blood (unlike human Factor IX complex), and is instead produced by a genetically ... Recombinant Coagulation Factor IX is a purified Factor IX glycoprotein produced by recombinant DNA technology ... It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, …
Matched Name: … Coagulation Factor IX (Recombinant) …
Matched Description: … It is not derived from human blood (unlike human Factor IX complex), and is instead produced by a genetically ... Recombinant Coagulation Factor IX is a purified Factor IX glycoprotein produced by recombinant DNA technology ... It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, …
Spesolimab
Spesolimab is an interleukin-36 (IL-36) receptor antagonist. It is a humanized monoclonal immunoglobulin G1 antibody that was produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology. The biosimilar of the drug, spesolimab-sbzo, was first approved by the FDA in September 2022 to treat generalized pustular psoriasis flares. Spesolimab...
Approved
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human interleukin 36 receptor) (humanized monoclonal BI 655130 gamma1-chain) …
Matched Description: … Spesolimab is an interleukin-36 (IL-36) receptor antagonist. ... humanized monoclonal immunoglobulin G1 antibody that was produced in Chinese hamster ovary (CHO) cells by recombinant ... A252220, A252225] Spesolimab received recommendations from the EMA's Committee for Medicinal Products for Human …
Matched Categories: … Interleukin Inhibitors ... Interleukin-36 Receptor Antagonist …
Matched Description: … Spesolimab is an interleukin-36 (IL-36) receptor antagonist. ... humanized monoclonal immunoglobulin G1 antibody that was produced in Chinese hamster ovary (CHO) cells by recombinant ... A252220, A252225] Spesolimab received recommendations from the EMA's Committee for Medicinal Products for Human …
Matched Categories: … Interleukin Inhibitors ... Interleukin-36 Receptor Antagonist …
Galsulfase
Galsufase is a variant form of the polymorphic human enzyme N-acetylgalactosamine 4-sulfatase of recombinant DNA origin. Galsulfase is a glycoprotein with a molecular weight of approximately 56 kD. The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation sites, four of which carry a bis mannose-6-phosphate...
Approved
Investigational
Matched Synonyms: … N-acetylgalactosamine-4-sulfatase, recombinant human …
Matched Description: … Galsufase is a variant form of the polymorphic human enzyme N-acetylgalactosamine 4-sulfatase of recombinant ... The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation …
Matched Description: … Galsufase is a variant form of the polymorphic human enzyme N-acetylgalactosamine 4-sulfatase of recombinant ... The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation …
Nesiritide
Nesiritide is a medication used to treat acutely decompensated congestive heart failure with dyspnea at rest or with minimal exertion (such as talk, eating or bathing). Nesiritide is a 32 amino acid recombinant human B-type natriuretic peptide.
Approved
Investigational
Matched Synonyms: … Nesiritide recombinant ... Human brain natriuretic factor-32 …
Matched Description: … Nesiritide is a 32 amino acid recombinant human B-type natriuretic peptide. …
Matched Description: … Nesiritide is a 32 amino acid recombinant human B-type natriuretic peptide. …
Antithrombin Alfa
Antithrombin Alfa is a recombinant antithrombin , an anticoagulant, that is used for the prevention of thromboembolic events in patients that have hereditary deficiency of antithrombin in high risk situations.
Approved
Investigational
Matched Synonyms: … Antithrombin (recombinant) ... Antithrombin III, recombinant ... Antithrombin III,recombinant …
Matched Description: … Antithrombin Alfa is a recombinant antithrombin , an anticoagulant, that is used for the prevention …
Matched Categories: … Recombinant Antithrombin …
Matched Description: … Antithrombin Alfa is a recombinant antithrombin , an anticoagulant, that is used for the prevention …
Matched Categories: … Recombinant Antithrombin …
Dibotermin alfa
Dibotermin alfa is a recombinant human bone morphogenetic protein-2 (rhBMP-2) derived from a recombinant Chinese Hamster Ovary (CHO) cell line [FDA Label]. It is implanted in patients undergoing bone surgeries or those with fractures. BMPs are subfamily of the transforming growth factor-β (TGF-β) superfamily that have different actions on the...
Approved
Investigational
Matched Synonyms: … Bone morphogenetic protein 2 (human recombinant rhBMP-2) …
Matched Description: … Dibotermin alfa is a recombinant human bone morphogenetic protein-2 (rhBMP-2) derived from a recombinant …
Matched Description: … Dibotermin alfa is a recombinant human bone morphogenetic protein-2 (rhBMP-2) derived from a recombinant …
Erythropoietin
Erythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red blood cells. It works by promoting the division and differentiation of committed erythroid progenitors in the bone marrow [FDA Label]. Epoetin alfa (Epoge) was developed by Amgen Inc. in 1983 as the first rhEPO...
Approved
Matched Synonyms: … Erythropoietin (recombinant human) ... Erythropoietin (human, recombinant) ... Epoetin alfa, recombinant …
Matched Description: … molecular weight of approximately 30,400 daltons and is produced by mammalian cells into which the human ... Epoetin alfa is a 165-amino acid erythropoiesis-stimulating glycoprotein produced in cell culture using recombinant …
Matched Description: … molecular weight of approximately 30,400 daltons and is produced by mammalian cells into which the human ... Epoetin alfa is a 165-amino acid erythropoiesis-stimulating glycoprotein produced in cell culture using recombinant …
Teduglutide
Teduglutide is a glucagon-like peptide-2 (GLP-2) analogue. It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant DNA technology. Teduglutide differs from GLP-2 by one amino acid (alanine is substituted by glycine). The significance of this substitution is that teduglutide...
Approved
Matched Synonyms: … Teduglutide Recombinant ... Glucagon-like peptide II (2-glycine) (human) …
Matched Description: … It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant …
Matched Description: … It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant …
Eptotermin alfa
A bone morphogenetic protein that is widely expressed during EMBRYONIC DEVELOPMENT. It is both a potent osteogenic factor and a specific regulator of nephrogenesis. Eptotermin alfa is an ingredient in the EMA-withdrawn product Osigraft.
Approved
Investigational
Withdrawn
Matched Synonyms: … Human recombinant bone morphogenetic protein 7 …
Alglucosidase alfa
Aglucosidase alfa consists of the human enzyme acid alpha-glucosidase (GAA) which is essential for the degradation of glygogen to glucose in lysosomes. It is encoded by the most predominant of nine observed haplotypes of this gene. Aglucosidase alfa is produced by recombinant DNA technology in a Chinese hamster ovary cell...
Approved
Matched Synonyms: … Human acid precursor alpha-glucosidase, recombinant …
Matched Description: … Aglucosidase alfa consists of the human enzyme acid alpha-glucosidase (GAA) which is essential for the ... Aglucosidase alfa is produced by recombinant DNA technology in a Chinese hamster ovary cell line. …
Matched Description: … Aglucosidase alfa consists of the human enzyme acid alpha-glucosidase (GAA) which is essential for the ... Aglucosidase alfa is produced by recombinant DNA technology in a Chinese hamster ovary cell line. …
Imlifidase
Chronic kidney disease (CKD) is a progressive and irreversible disease that represents a significant burden for both the individual and healthcare system at large. Currently available treatments for end-stage renal disease are limited to dialysis and renal transplantation, with the former associated with significant costs and lower quality of life.[A225836,A225916]...
Approved
Investigational
Matched Synonyms: … IdeS recombinant …
Matched Description: … [A225836,A225916] Patients who have developed human leukocyte antigen (HLA) sensitization from prior ... and eliminates Fc-dependent effector functions such as CDC and ADCC by cleaving the heavy chains of human …
Matched Description: … [A225836,A225916] Patients who have developed human leukocyte antigen (HLA) sensitization from prior ... and eliminates Fc-dependent effector functions such as CDC and ADCC by cleaving the heavy chains of human …
Janssen COVID-19 Vaccine
The Janssen COVID-19 vaccine (Ad26.COV2.S) is a recombinant vaccine that contains an adenovirus serotype 26 (Ad26) vector expressing a stabilized SARS-CoV-2 spike protein. The vaccine was created in collaboration with Johnson and Johnson (J&J), Janssen Pharmaceutical, and the Beth Israel Deaconess Medical Center. A preclinical study in hamsters infected with...
Approved
Investigational
Matched Synonyms: … AD26.COV2.S [RECOMBINANT] …
Matched Description: … The Janssen COVID-19 vaccine (Ad26.COV2.S) is a recombinant vaccine that contains an adenovirus serotype …
Matched Description: … The Janssen COVID-19 vaccine (Ad26.COV2.S) is a recombinant vaccine that contains an adenovirus serotype …
Darbepoetin alfa
Human erythropoietin with 2 aa substitutions to enhance glycosylation (5 N-linked chains), 165 residues (MW=37 kD). Produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology.
Approved
Investigational
Matched Synonyms: … Darbepoetin alfa,recombinant …
Matched Description: … Produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology. ... Human erythropoietin with 2 aa substitutions to enhance glycosylation (5 N-linked chains), 165 residues …
Matched Description: … Produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology. ... Human erythropoietin with 2 aa substitutions to enhance glycosylation (5 N-linked chains), 165 residues …
Ajmaline
An alkaloid found in the root of Rauwolfia serpentina, among other plant sources. It is a class Ia antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac action potentials. Ajmaline produces potent sodium channel blocking effects and a very short half-life which makes it a very...
Approved
Experimental
Matched Synonyms: … (5aR,6S,8S,10S,11S,11aS,12aR,13R)-5-methyl-5a,6,8,9,10,11,11a,12-octahydro-5H-6,10:11,12a-dimethanoindolo …
Salmon calcitonin
Synthetic peptide, 32 residues long formulated as a nasal spray.
Approved
Investigational
Matched Synonyms: … Calcitonin salmon recombinant ... Recombinant salmon calcitonin …
Hepatitis B immune globulin
Long-term hepatitis B immune globulin (HBIG) has been shown to reduce hepatitis B virus (HBV) reinfection in patients transplanted for hepatitis B. Infection with hepatitis B may lead to hepatocellular carcinoma, a type of liver cancer. Therefore, the hepatitis-B vaccines are cancer-preventing vaccines. According to the Centers for Disease Control...
Approved
Investigational
Matched Synonyms: … Hepatitis B immune globulin human ... Hepatitis B immune globulin (human) ... Human hepatitis B immunoglobulin …
Matched Categories: … Human Immunoglobulin …
Matched Categories: … Human Immunoglobulin …
Cholecystokinin
Cholecystokinin ( also known as CCK or CCK-PZ) is a peptide hormone of the gastrointestinal system which is responsible for stimulating the digestion of fat and protein. Cholecystokinin, previously called pancreozymin, is synthesized and secreted by enteroendocrine cells in the duodenum (the first portion of the small intestine) and leads...
Approved
Investigational
Matched Synonyms: … Human CCK-33 ... Human cholecystokinin-33 …
Prothrombin
Prothrombin Complex Concentrate (Human), is indicated for the urgent reversal of acquired coagulation factor deficiency induced by Vitamin K antagonist (VKA, e.g., warfarin) therapy in adult patients with acute major bleeding.
Approved
Matched Synonyms: … Coagulation factor II human ... Coagulation factor II (human) ... Human coagulation factor II …
Matched Description: … Prothrombin Complex Concentrate (Human), is indicated for the urgent reversal of acquired coagulation …
Matched Description: … Prothrombin Complex Concentrate (Human), is indicated for the urgent reversal of acquired coagulation …
Natalizumab
Natalizumab is a recombinant humanized IgG4κ monoclonal antibody that binds to α4-integrin. While natalizumab was originally approved by the FDA to treat multiple sclerosis in 2004, it was withdrawn from the market following multiple reports of fatal progressive multifocal leukoencephalopathy (PML). In 2006, the FDA reintroduced the drug to the...
Approved
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4 (HUMAN-MOUSE MONOCLONAL AN100226 4-CHAIN ANTI-HUMAN INTEGRIN 4), DISULFIDE WITH HUMAN-MOUSE ... IMMUNOGLOBULIN G4 (HUMAN-MOUSE MONOCLONAL AN100226 4-CHAIN ANTI-HUMAN INTEGRIN 4), DISULPHIDE WITH HUMAN-MOUSE …
Matched Description: … Natalizumab is a recombinant humanized IgG4κ monoclonal antibody that binds to α4-integrin. …
Matched Description: … Natalizumab is a recombinant humanized IgG4κ monoclonal antibody that binds to α4-integrin. …
Albumin iodinated I-125 serum
I-125 iodinated albumin is a radiolabeled albumin-based diagnostic agent used in the determination of total blood and plasma volume.
Approved
Matched Synonyms: … Human albumin I-125 ... Human serum albumin I-125 ... Iodinated (125I) human serum albumin …
Sotatercept
Sotatercept is an activin signalling inhibitor. It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. On March 26, 2024, sotatercept was approved by the FDA for the treatment of pulmonary arterial hypertension...
Approved
Investigational
Matched Synonyms: … (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN ... (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN ... IMMUNOGLOBULIN G1 (SYNTHETIC HUMAN HEAVY CHAIN FC FRAGMENT), DIMER …
Matched Description: … It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin ... receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. …
Matched Categories: … Recombinant Proteins ... Recombinant Fusion Proteins …
Matched Description: … It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin ... receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. …
Matched Categories: … Recombinant Proteins ... Recombinant Fusion Proteins …
Efbemalenograstim alfa
Efbemalenograstim alfa is a long-acting recombinant fusion protein of granulocyte-colony stimulating factor (G-CSF) due to the addition of the Fc portion of human IgG2, allowing for once-per-cycle administration.[L48852,A262167] As endogenous G-CSF mediates the differentiation of hematopoietic stem cells into granulocytes and eventually neutrophils, the administration of recombinant G-CSF like efbemalenograstim...
Approved
Matched Synonyms: … Recombinant dimeric g-csf fusion protein f627 …
Matched Description: … factor (G-CSF) due to the addition of the Fc portion of human IgG2, allowing for once-per-cycle administration ... Efbemalenograstim alfa is a long-acting recombinant fusion protein of granulocyte-colony stimulating ... differentiation of hematopoietic stem cells into granulocytes and eventually neutrophils, the administration of recombinant …
Matched Description: … factor (G-CSF) due to the addition of the Fc portion of human IgG2, allowing for once-per-cycle administration ... Efbemalenograstim alfa is a long-acting recombinant fusion protein of granulocyte-colony stimulating ... differentiation of hematopoietic stem cells into granulocytes and eventually neutrophils, the administration of recombinant …
Displaying drugs 551 - 575 of 3040 in total