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Displaying drugs 551 - 575 of 1022 in total
Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic. It has a very long half-life compared to other cephalosporins and is high penetrable into the meninges , eyes , and inner ear . Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins, but worse activity against methicillin-susceptible S.aureus. Ceftriaxone...
Approved
Matched Description: … meninges[A215582], eyes[A215647], and inner ear[A215627]. ... [A215582] It has a very long half-life compared to other cephalosporins and is high penetrable into the ... Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins …
Matched Products: … Ceftriaxone and Dextrose …
Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity. Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure than atenolol, propranolol, or pindolol. Nebivolol and other beta...
Approved
Investigational
Matched Description: … Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other ... [A182579] Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure ... [A182579] Nebivolol and other beta blockers are generally not first line therapies as many patients are …
Matched Salts name: … Nebivolol hydrochloride
Matched Categories: … Beta Blocking Agents and Thiazides ... valsartan and nebivolol ... nebivolol and amlodipine ... nebivolol and thiazides ... zofenopril and nebivolol …
Matched Products: … NEBIVOLOL HYDROCHLORIDE ... Nebivolol Hydrochloride ... VALENDE 5 MG TABLET, 28 ADET …
Eslicarbazepine acetate (ESL) is an anticonvulsant medication approved for use in Europe, the United States and Canada as an adjunctive therapy for partial-onset seizures that are not adequately controlled with conventional therapy. Eslicarbazepine acetate is a prodrug that is rapidly converted to eslicarbazepine, the primary active metabolite in the body....
Approved
Matched Synonyms: … Eslicarbazepine acetate ... (10S)-5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl acetate
Matched Name: … Eslicarbazepine acetate
Matched Iupac: … (9S)-2-carbamoyl-2-azatricyclo[9.4.0.0³,⁸]pentadeca-1(15),3,5,7,11,13-hexaen-9-yl acetate
Matched Description: … Eslicarbazepine acetate is marketed as Aptiom in North America and Zebinix or Exalief in Europe. ... States and Canada as an adjunctive therapy for partial-onset seizures that are not adequately controlled ... , but it is known that it does exert anticonvulsant activity by inhibiting repeated neuronal firing and
Matched Categories: … Eslicarbazepine and prodrugs …
Matched Products: … Eslicarbazepine acetate
Methylprednisolone is a prednisolone derivative glucocorticoid with higher potency than prednisone. It was first described in the literature in the late 1950s.[A188811,A188814] Methylprednisolone was granted FDA approval on 24 October 1957. In the outbreak of COVID-19, low dose methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with...
Approved
Vet approved
Matched Salts name: … Methylprednisolone acetate
Matched Categories: … Sex Hormones and Insulins ... methylprednisolone and antibiotics ... methylprednisolone and antiinfectives ... methylprednisolone and antiinfectives ... Ophthalmological and Otological Preparations …
Matched Products: … Methylprednisolone Acetate ... Methylprednisolone acetate ... Methylprednisolone Acetate Injectable Suspension USP …
Investigational
Matched Synonyms: … Quinine hydrochloride impurity B …
Experimental
Matched Name: … PHENYLALANINE BORONIC ACID …
Valsartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes telmisartan, candesartan, losartan, olmesartan, and irbesartan. ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of aldosterone...
Approved
Investigational
Matched Synonyms: … N-(P-(O-1H-Tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valine ... (S)-N-Valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine ... N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine
Matched Description: … aldosterone and ADH, cardiac stimulation, and renal reabsorption of sodium, among others. ... and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of ... regulation of kidney, vascular, and cardiac functions. …
Matched Mixtures name: … Valsartan and Hydrochlorothiazide ... Valsartan and Hydrochlorothiazide ... Valsartan and Hydrochlorothiazide …
Matched Categories: … Angiotensin II Antagonists and Diuretics ... Angiotensin II Antagonists and Calcium Channel Blockers ... valsartan and nebivolol ... valsartan and diuretics ... valsartan and aliskiren …
Experimental
Matched Name: … L-Threoninol
HMI-102 is an investigational gene therapy designed to encode the phenylalanine-4-hydroxylase (PAH) gene, mutated in people with phenylketonuria.
Investigational
Matched Synonyms: … Recombinant adeno-associated viral vector serotype HSC expressing human phenylalanine hydroxylase …
Matched Description: … HMI-102 is an investigational gene therapy designed to encode the phenylalanine-4-hydroxylase (PAH) gene …
Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Approved
Matched Description: … It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus …
Matched Categories: … cefuroxime and metronidazole …
Matched Products: … Cefuroxime and Dextrose …
A narcotic analgesic with a long onset and duration of action. It is used mainly in the treatment of narcotic dependence.
Experimental
Illicit
Matched Synonyms: … Methadyl acetate
Matched Name: … Methadyl acetate
Matched Iupac: … 6-(dimethylamino)-4,4-diphenylheptan-3-yl acetate
Matched Description: … A narcotic analgesic with a long onset and duration of action. …
Matched Salts name: … Methadyl acetate hydrochloride
Zuretinol acetate has been used in trials studying the treatment of Impaired Dark Adaptation, RP (Retinitis Pigmentosa), Retinitis Pigmentosa (RP), and LCA (Leber Congenital Amaurosis).
Investigational
Matched Synonyms: … Zuretinol acetate
Matched Name: … Zuretinol acetate
Matched Iupac: … (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-yl acetate
Matched Description: … Pigmentosa), Retinitis Pigmentosa (RP), and LCA (Leber Congenital Amaurosis). ... Zuretinol acetate has been used in trials studying the treatment of Impaired Dark Adaptation, RP (Retinitis …
Experimental
Matched Synonyms: … Bisoxatin acetate
Matched Name: … Bisoxatin acetate
Matched Iupac: … 4-{2-[4-(acetyloxy)phenyl]-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl}phenyl acetate
Experimental
Matched Synonyms: … Flurandrenolone acetate
Matched Name: … Flurandrenolide acetate
Matched Iupac: … tetramethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-17-en-8-yl]-2-oxoethyl acetate
Chlormadinone acetate is a progesterone derivative first synthesized in 1961. In the US, chlormadinone acetate was formerly marketed as a component of the combination drug products Estalor-21 and C-Quens. However, the use of these drugs was associated with the development of mammary tumors in dogs. In 1972, the FDA withdrew...
Experimental
Withdrawn
Matched Synonyms: … Chlormadinone acetate
Matched Name: … Chlormadinone acetate
Matched Iupac: … -9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl acetate
Matched Description: … Estalor-21 and C-Quens. ... efficacy and tolerability. ... Chlormadinone acetate is a progesterone derivative first synthesized in 1961. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Experimental
Matched Synonyms: … Terpineol acetate
Matched Name: … Terpinyl acetate
Matched Iupac: … 2-(4-methylcyclohex-3-en-1-yl)propan-2-yl acetate
Experimental
Matched Name: … Tryptophanyl-5'amp …
Chrysalin has been used in trials studying the treatment of Radius Fracture.
Investigational
Matched Synonyms: … Rusalatide acetate
Matched Name: … Rusalatide acetate
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Experimental
Matched Synonyms: … Dienestrol acetate
Matched Iupac: … 4-[(2E,4E)-4-[4-(acetyloxy)phenyl]hexa-2,4-dien-3-yl]phenyl acetate
Experimental
Matched Name: … Nz-(1-Carboxyethyl)-Lysine
Experimental
Matched Products: … LYSEEN
Beludavimab is under investigation in clinical trial NCT04746183 (AGILE (Early Phase Platform Trial for COVID-19)).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1 (246-ALANINE,340-LEUCINE,342-GLUTAMIC ACID,438-LEUCINE,444-SERINE), ANTI-(SEVERE ACUTE …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ganirelix is a synthetic decapeptide and a competitive gonadotropin-releasing hormone (GnRH) antagonist. Derived from endogenous GnRH, ganirelix has amino acid substitutions. Ganirelix is indicated for controlled ovarian hyperstimulation in assisted reproduction techniques. The first case of pregnancy achieved after the use of ganirelix in an assisted reproduction program was reported...
Approved
Matched Description: … Ganirelix is a synthetic decapeptide and a competitive gonadotropin-releasing hormone (GnRH) antagonist …
Matched Salts name: … Ganirelix acetate
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Ganirelix Acetate
Experimental
Matched Synonyms: … L-tryptophan amide …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Flavoring agent sweeter than sugar, metabolized as phenylalanine and aspartic acid.
Investigational
Nutraceutical
Matched Synonyms: … 1-methyl N-L-α-aspartyl-L-phenylalanate ... 1-Methyl N-L-alpha-aspartyl-L-phenylalanate ... L-Aspartyl-L-phenylalanine methyl ester …
Matched Description: … Flavoring agent sweeter than sugar, metabolized as phenylalanine and aspartic acid. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Diet, Food, and Nutrition …
Displaying drugs 551 - 575 of 1022 in total