Did you mean acetyl acid and approved type?
Displaying drugs 551 - 575 of 11064 in total
Tecovirimat
The World Health Organization declared smallpox, a contagious and sometimes fatal infectious disease, eradicated in 1980. However, there have been longstanding concerns that smallpox may be used as a bioweapon.[A35133,L3614] Tecovirimat is an antiviral drug that was identified via a high-throughput screen in 2002. It is effective against all orthopoxviruses,...
Approved
Investigational
Matched Description: … [A35133,L3614] Tecovirimat is an antiviral drug that was identified via a high-throughput screen in 2002 ... [A35131,A35143]
Tecovirimat was approved by the FDA in July 2018 as the first drug ever approved to ... [L3626, L3614] Tecovirimat was later approved by Health Canada in December 2021,[L39397] followed by …
Amikacin
Amikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A.[FDA label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group of the deoxystreptamine moiety of kanamycin A. Amikacin's unique property is that it exerts activity against more resistant gram-negative bacilli such as...
Approved
Investigational
Vet approved
Matched Description: … M. avium-intracellulare (MAC) is a type of nontuberculous mycobacteria (NTM) found in water and soil. ... [F1949] In September 2018, a liposomal inhalation suspension of this drug was approved by the FDA for ... [L4680]
Several forms of amikacin are used currently, including an intravenous (IV) or intramuscular …
Motixafortide
Motixafortide is a cyclic peptide hematopoietic stem cell mobilizer used to improve stem cell collection prior to autologous transplantation. Hematopoietic stem cell transplantation (HSCT) is commonly employed in the context of hematologic cancers - high-dose chemotherapy regimens destroy cancerous blood cells, which are then replaced via infusion of the patient's...
Approved
Investigational
Matched Description: … [L48136] Similar in mechanism to the previously approved [plerixafor], motixafortide is an inhibitor ... [A261476]
Motixafortide was approved by the FDA in September 2023, in combination with filgrastim ... destroy cancerous blood cells, which are then replaced via infusion of the patient's own stem cells (i.e. an …
Susoctocog alfa
Intravenous susoctocog alfa is a recombinant, B-domain deleted, porcine sequence antihaemophilic factor VIII (FVIII) product that has recently been approved for the treatment of bleeding episodes in adults with acquired haemophilia A (AHA). AHA is a rare bleeding disorder that results in a prolonged clotting time as measured by the...
Approved
Investigational
Matched Description: … chain and a 80 kDa light chain with the naturally-occuring B domain replaced with a twenty-four amino acid ... B-domain deleted, porcine sequence antihaemophilic factor VIII (FVIII) product that has recently been approved ... It is the first recombinant porcine FVIII treatment approved for AHA that allows physicians to manage …
Dibenzepin
Dibenzepin is approved for use in Europe.
Approved
Matched Description: … Dibenzepin is approved for use in Europe. …
Cilazapril
Cilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure. It belongs to the angiotensin-converting enzyme inhibitors (ACE inhibitors) class of drugs. It is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat. It is branded as Inhibace in Canada and...
Approved
Matched Iupac: … ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-10-oxo-octahydro-1H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid …
Matched Description: … Cilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure. …
Matched Description: … Cilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure. …
Pholcodine
Pholcodine formula is 3-o-morpholinoethylmorphine and it is classified as an antitussive which is defined as an opioid cough suppressant. It belongs to the opioid family of compounds and it is widely used. Pholcodine activity is the suppression of unproductive cough and it also has a mild sedative effect with little...
Approved
Illicit
Matched Description: … Pholcodine is not approved in Canada. ... as an opioid cough suppressant. ... Pholcodine formula is 3-o-morpholinoethylmorphine and it is classified as an antitussive which is defined …
Avacincaptad pegol
Avacincaptad pegol is an RNA aptamer covalently bound to a branched polyethylene glycol (PEG) molecule. It was developed to treat an advanced form of age-related macular degeneration (AMD) called geographic atrophy (GA). AMD is the leading cause of vision loss in developed countries for people over 50 years old, with...
Approved
Investigational
Matched Description: … Avacincaptad pegol is an RNA aptamer covalently bound to a branched polyethylene glycol (PEG) molecule ... It was developed to treat an advanced form of age-related macular degeneration (AMD) called geographic ... [A260801]
Avacincaptag pegol was approved by the FDA on August 4, 2023, under the brand name IZERVAY …
Articaine
Articaine is a dental local anesthetic. Articaine is widely used around the world and is the most popular local anesthetic in many European countries.
Approved
Dalfampridine
Dalfampridine is a potassium channel blocker used to help multiple sclerosis patients walk. This is the first drug that was specifically approved to help with mobility in these patients. FDA approved on January 22, 2010.
Approved
Matched Description: … FDA approved on January 22, 2010. ... This is the first drug that was specifically approved to help with mobility in these patients. …
Busulfan
Busulfan is a bifunctional alkylating agent, having a selective immunosuppressive effect on bone marrow. It is not a structural analog of the nitrogen mustards. It has been used in the palliative treatment of chronic myeloid leukemia (myeloid leukemia, chronic), but although symptomatic relief is provided, no permanent remission is brought...
Approved
Investigational
Magnesium trisilicate
Magnesium trisilicate is an inorganic compound that is used as an antacid in the treatment of peptic ulcers.
Approved
Matched Description: … Magnesium trisilicate is an inorganic compound that is used as an antacid in the treatment of peptic …
Matched Categories: … Gastric Acid Lowering Agents …
Matched Categories: … Gastric Acid Lowering Agents …
Pivmecillinam
Pivmecillinam is a mecillinam prodrug, a pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa. It is active against gram-negative organisms and used as for amdinocillin. [PubChem]
Approved
Alfuzosin
Benign prostatic hyperplasia (BPH) refers to a benign growth or hyperplasia of the prostate and leads to lower urinary tract symptoms in men, such as urgency, frequency and changes to urine flow. The prevalence of BPH is as high as 50%-60% for males in their 60's, and this prevalence increases...
Approved
Investigational
Matched Description: … [A228483] Alfuzosin is an alpha-1 adrenergic blocker used in the symptomatic treatment of BPH that works ... [L31593] It was initially approved by the FDA in 2003 and is marketed by several pharmaceutical companies …
Buclizine
Buclizine is an antihistamine medication with both antiemetic and anticholinergic effects , belonging to the piperazine derivative family of drugs. It was manufactured by Stuart Pharms and initially approved by the FDA in 1957. Following this, it was touted to be effective as an appetite stimulant in children when administered...
Approved
Matched Description: … It was manufactured by Stuart Pharms and initially approved by the FDA in 1957. ... Buclizine is an antihistamine medication with both antiemetic and anticholinergic effects [L6220], belonging ... [L6217] Following this, it was touted to be effective as an appetite stimulant in children when administered …
Homatropine
Homatropine is an anticholinergic drug that acts as an antagonist at muscarinic acetylcholine receptors. It is present in antitussives, under the trade name Hycodan, in combination with hydrocodone (dihydrocodeinone) bitartrate indicated for the symptomatic relief of cough as oral tablets or solutions. Homatropine is included in subtherapeutic amounts as homatropine...
Approved
Matched Description: … Homatropine is an anticholinergic drug that acts as an antagonist at muscarinic acetylcholine receptors ... accomodation, and to induce mydriasis (the dilation of the pupil); however such therapeutic use has not been approved …
Lactitol
Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from lactose. It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet as table sugar (i.e. sucrose). Clinically, lactitol has been investigated for use as an osmotic laxative and, along with other non-absorbable disaccharides...
Approved
Investigational
Matched Description: … [A190915,A190918]
Pizensy, an oral lactitol powder for solution, was approved by the FDA for use in ... [A190912] Clinically, lactitol has been investigated for use as an osmotic laxative and, along with other …
Hydroxocobalamin
Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B 12 that has been used therapeutically to treat vitamin B 12 deficiency. It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia.
Approved
Matched Description: … Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B …
Matched Categories: … Vitamin B12 and Folic Acid …
Matched Categories: … Vitamin B12 and Folic Acid …
Colchicine
Colchicine is an alkaloid drug derived from a plant belonging to the Lily family, known as Colchicum autumnale, or "autumn crocus." Its use was first approved by the FDA in 1961. Colchicine is used in the treatment of gout flares and Familial Mediterranean fever, and prevention of major cardiovascular events....
Approved
Matched Description: … [A183611] Its use was first approved by the FDA in 1961. ... Colchicine is an alkaloid drug derived from a plant belonging to the Lily family, known as _Colchicum …
Matched Categories: … Preparations With No Effect on Uric Acid Metabolism …
Matched Categories: … Preparations With No Effect on Uric Acid Metabolism …
Idelalisib
Idelalisib is a phosphoinositide 3-kinase inhibitor indicated in the treatment of chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL). For the treatment of relapsed CLL, it is currently indicated as a second-line agent in combination with rituximab in patients for whom rituximab...
Approved
Matched Description: … 5 and type 4 signalling, which are involved in trafficking and homing of B-cells to the lymph nodes ... several cell signaling pathways, including B-cell receptor (BCR) signaling and C-X-C chemokine receptors type …
Nylidrin
Nylidrin, also known as buphenine belongs to the category of drugs called vasodilators, which relax blood vessels and increase blood flow. Nylidrin is a peripheral vasodilator. Some studies show the evidence of improving cognitive impairment in selected individuals, such as geriatric patients with mild to moderate symptoms of cognitive, emotional...
Approved
Chikungunya vaccine (live, attenuated)
Chikungunya virus (CHIKV) is a member of the Alphavirus genus that was first identified in Tanzania in 1952. It is spread primarily by the bite of infected mosquitos of the Aedes genus. Infection with CHIKV causes chikungunya fever, an illness characterized by acute fever and severe, persistent arthralgia. Prior to...
Approved
Matched Description: … Infection with CHIKV causes chikungunya fever, an illness characterized by acute fever and severe, persistent ... [L48786] There are no approved treatments for active chikungunya virus infection. ... [L48731]
Chikungunya vaccine (live, attenuated) - marketed under the name Ixchiq - was approved by …
Recombinant stabilized RSV B prefusion F antigen
Recombinant stabilized RSV B prefusion F antigen is one component of a bivalent respiratory syncytial virus (RSV) vaccine called Abrysvo. The vaccine comprises two antigens - the other being recombinant stabilized RSV A prefusion F antigen - which have been expressed in Chinese hamster ovary cell lines and then purified...
Approved
Matched Description: … is reconstituted with sterile water prior to injection and does not require the co-administration of an ... [L49555] Abrysvo was approved for the same indications in the EU in August 2023[L49565] and Canada in ... [L49560] It is the first RSV vaccine approved for use in pregnant patients to prevent RSV in infants. …
Adalimumab
Adalimumab is a subcutaneously administered biological disease modifier for the treatment of rheumatoid arthritis and other chronic debilitating diseases mediated by tumor necrosis factor.[A39984,A39999] It was originally launched by Abbvie in the U.S. and approved in 2002 by the FDA. This drug is frequently known as Humira. It is produced...
Approved
Experimental
Matched Description: … - which was approved in August 2022 -,[L42935] and adalimumab-aacf - which was approved in October 2023 ... [L44953] Adalimumab-adaz was approved by the FDA on October 31, 2018. ... Adalimumab-atto was the first adalimumab biosimilar approved by the FDA in 2016. …
Displaying drugs 551 - 575 of 11064 in total