Displaying drugs 576 - 600 of 2103 in total
Mimosine
Mimosine is an antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca.
Experimental
Matched Synonyms: … (S)-2-amino-3-(3-hydroxy-4-oxo-4H-pyridin-1-yl)propanoate ... (L)-Mimosine ... L-Mimosine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
N-(R-Carboxy-Ethyl)-Alpha-(S)-(2-Phenylethyl)
Experimental
Matched Name: … N-(R-Carboxy-Ethyl)-Alpha-(S)-(2-Phenylethyl) …
Mitomycin
Mitomycin is an antineoplastic antibiotic first isolated by Japanese microbiologists in the 1950s from cultures of Streptomyces caespitosus.[L12867,A193419] It is an alkylating agent that inhibits DNA synthesis (and, at higher concentrations, RNA and protein synthesis) by cross-linking the complementary strands of the DNA double helix. Few other antibiotics have been...
Approved
Matched Synonyms: … Mitocin-C ... Mitomycin C ... Mitomycin-C …
Matched Iupac: … -1(9),11-dien-8-yl]methyl carbamate ... [(4S,6S,7R,8S)-11-amino-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.0^{2,7}.0^{4,6}]trideca …
Matched Description: … , RNA and protein synthesis) by cross-linking the complementary strands of the DNA double helix. ... [L12867,A193419] It is an alkylating agent that inhibits DNA synthesis (and, at higher concentrations ... Upper Tract Urothelial Cancer (LG-UTUC)[L12867] - as well as adjunctly to _ab externo_ glaucoma surgeries …
Matched Categories: … Indicators and Reagents ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … MITOMYCIN C ... MITOMYCIN-C KYOWA FOR INJECTION 2 mg/vial ... MITOMYCIN-C KYOWA FOR INJECTION 10 mg/vial …
Matched Iupac: … -1(9),11-dien-8-yl]methyl carbamate ... [(4S,6S,7R,8S)-11-amino-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.0^{2,7}.0^{4,6}]trideca …
Matched Description: … , RNA and protein synthesis) by cross-linking the complementary strands of the DNA double helix. ... [L12867,A193419] It is an alkylating agent that inhibits DNA synthesis (and, at higher concentrations ... Upper Tract Urothelial Cancer (LG-UTUC)[L12867] - as well as adjunctly to _ab externo_ glaucoma surgeries …
Matched Categories: … Indicators and Reagents ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … MITOMYCIN C ... MITOMYCIN-C KYOWA FOR INJECTION 2 mg/vial ... MITOMYCIN-C KYOWA FOR INJECTION 10 mg/vial …
Cholic Acid
A major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. [PubChem]
Cholic acid, formulated as Cholbam capsules, is approved by the United States Food and Drug Administration as a treatment for children and adults with bile acid...
Approved
Matched Synonyms: … Cholic Acid …
Matched Name: … Cholic Acid …
Matched Iupac: … (4R)-4-[(1R,3aS,3bR,4R,5aS,7R,9aS,9bS,11S,11aR)-4,7,11-trihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta …
Matched Description: … [PubChem] Cholic acid, formulated as Cholbam capsules, is approved by the United States Food and Drug ... It facilitates fat absorption and cholesterol excretion. ... A major primary bile acid produced in the liver and usually conjugated with glycine or taurine. …
Matched Categories: … Bile Acids and Salts ... Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Bile acids and derivatives ... Cholanes …
Matched Name: … Cholic Acid …
Matched Iupac: … (4R)-4-[(1R,3aS,3bR,4R,5aS,7R,9aS,9bS,11S,11aR)-4,7,11-trihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta …
Matched Description: … [PubChem] Cholic acid, formulated as Cholbam capsules, is approved by the United States Food and Drug ... It facilitates fat absorption and cholesterol excretion. ... A major primary bile acid produced in the liver and usually conjugated with glycine or taurine. …
Matched Categories: … Bile Acids and Salts ... Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Bile acids and derivatives ... Cholanes …
Alrizomadlin
Alrizomadlin is a novel MDM2 inhibitor that blocks the interaction of MDM2 and p53. It is being investigated in cancers.[A257281,A257286]
Investigational
Matched Synonyms: … (3'r,4's,5'r)-4-((6-chloro-2-oxo-1,2-dihydro-spiro(indole-3,3'-pyrrolidin)e-4'-(3-chloro-2-fluoro -phenyl ... Bicyclo(2.2.2)octane-1-carboxylic acid, 4-((((3'r,4's,5'r)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-1' ... 4-((3'R,4'S,5'R)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine …
Matched Iupac: … 4-{[(3'R,4'S,5'R)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxo-1'',2''-dihydrodispiro[cyclohexane …
Matched Description: … Alrizomadlin is a novel MDM2 inhibitor that blocks the interaction of MDM2 and p53. …
Matched Iupac: … 4-{[(3'R,4'S,5'R)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxo-1'',2''-dihydrodispiro[cyclohexane …
Matched Description: … Alrizomadlin is a novel MDM2 inhibitor that blocks the interaction of MDM2 and p53. …
N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium
Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
Experimental
Matched Synonyms: … Choline, dihydrogen phosphate (ester) (8CI) …
Matched Description: … Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction. …
Matched Description: … Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction. …
(R)-Rolipram
The (R)-enantiomer of rolipram, it is a phosphodiesterase inhibitor with antidepressant properties.
Experimental
Matched Synonyms: … R-rolipram ... (R)-(-)-rolipram ... (R)-(−)-rolipram …
Matched Name: … (R)-Rolipram …
Matched Description: … The (R)-enantiomer of rolipram, it is a phosphodiesterase inhibitor with antidepressant properties. …
Matched Name: … (R)-Rolipram …
Matched Description: … The (R)-enantiomer of rolipram, it is a phosphodiesterase inhibitor with antidepressant properties. …
Vudalimab
Vudalimab is under investigation in clinical trial NCT05005728 (Xmab®20717 (Vudalimab) Alone or in Combination With Chemotherapy or Targeted Therapy in Patients With Metastatic Castration-resistant Prostate Cancer).
Investigational
Matched Synonyms: … protein 4, cd152)) and anti-(homo sapienspdcd1 (programmed cell death 1, pd-1, pd1, cd279)), monoclonal ... Immunoglobulin half-ig g1-kappa/scfv-h-ch2-ch3, anti-(homo sapiens ctla4 (cytotoxic t-lymphocyte-associated …
(R)-1-phenylethanol
Experimental
Matched Synonyms: … (R)-α-methylbenzyl alcohol ... (R)-α-methylbenzenemethanol ... (R)-alpha-methylbenzenemethanol …
Matched Name: … (R)-1-phenylethanol …
Matched Name: … (R)-1-phenylethanol …
Isoprenaline
Isoprenaline is a non-selective beta adrenergic receptor agonist indicated to treat heart block, Adams-Stokes attacks, bronchospasm in anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion, congestive hear failure, and cardiogenic shock.[A15638,L33160]
Isoprenaline research in the 1940s found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising...
Approved
Investigational
Matched International brands: … Proternol L …
Matched Description: … anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion, congestive hear failure, and ... [A233724,A233729] The US patent from 1943 states that this compound had a wider therapeutic index and ... found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising the heart rate and …
Matched Categories: … Adrenergic and Dopaminergic Agents ... isoprenaline and other drugs for obstructive airway diseases …
Matched Products: … Isuprel Liq 0.5% ... Isuprel Liq Inh 0.5% ... Isuprel Liq 0.2mg/ml …
Matched Description: … anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion, congestive hear failure, and ... [A233724,A233729] The US patent from 1943 states that this compound had a wider therapeutic index and ... found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising the heart rate and …
Matched Categories: … Adrenergic and Dopaminergic Agents ... isoprenaline and other drugs for obstructive airway diseases …
Matched Products: … Isuprel Liq 0.5% ... Isuprel Liq Inh 0.5% ... Isuprel Liq 0.2mg/ml …
Levosalbutamol
Levosalbutamol, or levalbuterol, is a short-acting β2 adrenergic receptor agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).
Salbutamol has been marketed as a racemic mixture, although beta2-agonist activity resides almost exclusively in the (R)-enantiomer. The enantioselective disposition of salbutamol and the possibility that (S)-salbutamol has...
Approved
Investigational
Matched Synonyms: … R-salbutamol ... (R)-salbutamol …
Matched Description: … The enantioselective disposition of salbutamol and the possibility that (S)-salbutamol has adverse effects ... have led to the development of an enantiomerically pure (R)-salbutamol formulation known as levosalbutamol ... , or levalbuterol, is a short-acting β2 adrenergic receptor agonist used in the treatment of asthma and …
Matched Description: … The enantioselective disposition of salbutamol and the possibility that (S)-salbutamol has adverse effects ... have led to the development of an enantiomerically pure (R)-salbutamol formulation known as levosalbutamol ... , or levalbuterol, is a short-acting β2 adrenergic receptor agonist used in the treatment of asthma and …
Barium sulfate
Barium sulfate is an inorganic compound with the chemical formula BaSO4 .
Barium sulfate occurs in nature as the mineral barite. It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield .
This drug is used as a contrast agent in...
Approved
Matched Description: … and high level of clearance from the body [FDA label]. ... This drug is used as a contrast agent in diagnostic x-ray procedures. ... It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation …
Matched Categories: … X-Ray Contrast Activity ... X-Ray Contrast Media, Non-Iodinated ... Barium Sulfate Containing X-Ray Contrast Media …
Matched Products: … Medebar Plus - Sus Orl RT 56%w/w 100%w/v ... Liquid Barosperse- Sus Orl RT 60%w/v 40%w/w ... Liqui-coat Hd - Sus Orl 210%w/v 81%w/w …
Matched Categories: … X-Ray Contrast Activity ... X-Ray Contrast Media, Non-Iodinated ... Barium Sulfate Containing X-Ray Contrast Media …
Matched Products: … Medebar Plus - Sus Orl RT 56%w/w 100%w/v ... Liquid Barosperse- Sus Orl RT 60%w/v 40%w/w ... Liqui-coat Hd - Sus Orl 210%w/v 81%w/w …
G4460
Investigational
Matched Synonyms: … c-myb antisense oligodeoxynucleotide ... c-myb antisense oligonucleotide G4460 …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Levomethadone
Experimental
Matched Products: … L-Polamidon 20 mg Tabletten ... L-Polamidon 5 mg Tabletten ... L-Polamidon Lösung zur Substitution …
Sirpiglenastat
Sirpiglenastat, also known as DRP-104, is a prodrug of 6-diazo-5-oxo-L-norleucine (DON), which is a broad-acting glutamine antagonist. It is under investigation in clinical trial NCT04471415 (Study to Investigate DRP-104 in Adults With Advanced Solid Tumors).
Investigational
Matched Synonyms: … (s)-isopropyl 2-((s)-2-acetamido-3-(1h-indol-3-yl)propanamido)-6-diazo-5-oxohexanoate ... L-norleucine, n-acetyl-l-tryptophyl-6-diazo-5-oxo-, 1-methylethyl ester ... Propan-2-yl (2s)-2-((n-acetyl-l-tryptophyl)amino)-6-diazo-5-oxohexanoate …
Matched Description: … Sirpiglenastat, also known as DRP-104, is a prodrug of [6-diazo-5-oxo-L-norleucine] (DON), which is a …
Matched Description: … Sirpiglenastat, also known as DRP-104, is a prodrug of [6-diazo-5-oxo-L-norleucine] (DON), which is a …
Methyldopa
Methyldopa, or α-methyldopa, is a centrally acting sympatholytic agent and an antihypertensive agent. It is an analog of DOPA (3,4‐hydroxyphenylanine), and it is a prodrug, meaning that the drug requires biotransformation to an active metabolite for therapeutic effects. Methyldopa works by binding to alpha(α)-2 adrenergic receptors as an agonist, leading...
Approved
Matched Synonyms: … (S)-(-)-alpha-Methyldopa ... L-Methyl Dopa ... α-methyl-L-dopa …
Matched Description: … [A1499] Methyldopa exists in two isomers D-α-methyldopa and L-α-methyldopa, which is the active form. ... Methyldopa, or α-methyldopa, is a centrally acting sympatholytic agent and an antihypertensive agent. ... [A231784] It is an analog of DOPA (3,4‐hydroxyphenylanine), and it is a prodrug, meaning that the drug …
Matched Mixtures name: … Methyldopa and Hydrochlorothiazide ... Methyldopa and Hydrochlorothiazide ... Methyldopa and Hydrochlorothiazide …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Aromatic L-amino Acid Decarboxylase Inhibitors …
Matched Description: … [A1499] Methyldopa exists in two isomers D-α-methyldopa and L-α-methyldopa, which is the active form. ... Methyldopa, or α-methyldopa, is a centrally acting sympatholytic agent and an antihypertensive agent. ... [A231784] It is an analog of DOPA (3,4‐hydroxyphenylanine), and it is a prodrug, meaning that the drug …
Matched Mixtures name: … Methyldopa and Hydrochlorothiazide ... Methyldopa and Hydrochlorothiazide ... Methyldopa and Hydrochlorothiazide …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Aromatic L-amino Acid Decarboxylase Inhibitors …
Rescinnamine
Rescinnamine is an angiotensin-converting enzyme inhibitor used as an antihypertensive drug. It is an alkaloid obtained from Rauwolfia serpentina and other species of Rauwolfia.
Approved
Matched International brands: … Tsuruselpi S …
Matched Description: … It is an alkaloid obtained from _Rauwolfia serpentina_ and other species of _Rauwolfia_. …
Matched Categories: … rescinnamine and diuretics ... rescinnamine and diuretics, combinations with other drugs …
Matched Description: … It is an alkaloid obtained from _Rauwolfia serpentina_ and other species of _Rauwolfia_. …
Matched Categories: … rescinnamine and diuretics ... rescinnamine and diuretics, combinations with other drugs …
R-851
R-851 is part of the family of immune response modifier (IRM) and it acts in a novel way to stimulate the human body's immnune system to attack virus-infected cells and tumor cells. It is expected to be topical treatment for cervical displasia and cervical high-risk human papillomavirus (HPV), the sexually...
Investigational
Matched Name: … R-851 …
Matched Description: … R-851 is part of the family of immune response modifier (IRM) and it acts in a novel way to stimulate ... the human body's immnune system to attack virus-infected cells and tumor cells. ... It is expected to be topical treatment for cervical displasia and cervical high-risk human papillomavirus …
Matched Description: … R-851 is part of the family of immune response modifier (IRM) and it acts in a novel way to stimulate ... the human body's immnune system to attack virus-infected cells and tumor cells. ... It is expected to be topical treatment for cervical displasia and cervical high-risk human papillomavirus …
R-95845
R-95845 is an inhibitor of HIV-1 reverse transcriptase.
Experimental
Matched Name: … R-95845 …
Matched Description: … R-95845 is an inhibitor of HIV-1 reverse transcriptase. …
Matched Description: … R-95845 is an inhibitor of HIV-1 reverse transcriptase. …
BACTEK-R
MV130 contains different components of whole heat-inactivated gram-positive and -negative bacteria that are involved in upper and lower respiratory infections. These include streptococcus pneumoniae and staphylococcus aureus. Though studies have shown that it reduces the rate of infections in recurrent respiratory tract infections (RRTIs), the complete mechanisms are not fully...
Investigational
Matched Name: … BACTEK-R …
Matched Description: … are involved in upper and lower respiratory infections. ... These include streptococcus pneumoniae and staphylococcus aureus. ... MV130 contains different components of whole heat-inactivated gram-positive and -negative bacteria that …
Matched Description: … are involved in upper and lower respiratory infections. ... These include streptococcus pneumoniae and staphylococcus aureus. ... MV130 contains different components of whole heat-inactivated gram-positive and -negative bacteria that …
(R)-etodolac
Investigational
Matched Synonyms: … (-)-(r)-etodolac ... R-etodolac ... Etodolac, (R)- …
Matched Name: … (R)-etodolac …
Matched Name: … (R)-etodolac …
Alpha-1-proteinase inhibitor
Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and zinc chloride fractionation.
Approved
Matched Description: … inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and …
Matched Mixtures name: … Prolastin-C …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … Prolastin-C ... PROLASTIN® C ... Prolastin-C Liquid …
Matched Mixtures name: … Prolastin-C …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … Prolastin-C ... PROLASTIN® C ... Prolastin-C Liquid …
Displaying drugs 576 - 600 of 2103 in total