Displaying drugs 576 - 600 of 6317 in total
Salix nigra pollen
Salix nigra pollen is the pollen of the Salix nigra plant. Salix nigra pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 11 Tree Pollen Mix ... 11 Tree Pollen Mix ... 11 Tree Pollen Mix …
Acer saccharum pollen
Acer saccharum pollen is the pollen of the Acer saccharum plant. Acer saccharum pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 2 Maple Pollen Mix ... 3 Maple Pollen Mix ... 2 Maple Pollen Mix …
Estradiol benzoate
Estradiol Benzoate is a pro-drug ester of DB00783, a naturally occurring hormone that circulates endogenously within the human body. Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex hormone. As a pro-drug of estradiol, estradiol benzoate therefore has the same downstream...
Approved
Investigational
Vet approved
Matched Iupac: … (1S,3aS,3bR,9bS,11aS)-1-hydroxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthren …
Matched Description: … produced with an ester side-chain as endogenous estradiol has very low oral bioavailability on its own (2- ... Estradiol Benzoate is a pro-drug ester of [DB00783], a naturally occurring hormone that circulates endogenously ... As a pro-drug of estradiol, estradiol benzoate therefore has the same downstream effects within the body …
Matched Description: … produced with an ester side-chain as endogenous estradiol has very low oral bioavailability on its own (2- ... Estradiol Benzoate is a pro-drug ester of [DB00783], a naturally occurring hormone that circulates endogenously ... As a pro-drug of estradiol, estradiol benzoate therefore has the same downstream effects within the body …
Fluconazole
Fluconazole, commonly known as Diflucan, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues. It was initially approved by the FDA in 1990. This drug is an azole antifungal, in the same drug family as ketoconazole and itraconazole. Fluconazole...
Approved
Investigational
Matched Iupac: … 2-(2,4-difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol …
Matched Description: … is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a …
Matched Mixtures name: … Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4% ... Ciclopirox 8% / Fluconazole 1% / Terbinafine HCl 1% ... Canesoral Combi 1 Day …
Matched Products: … Fluconazol B. Braun 2 mg/ml Infusionslösung ... CANDIDIN 50 MG KAPSÜL, 3 ADET ... FLUCONAZOLO B. BRAUN …
Matched Description: … is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a …
Matched Mixtures name: … Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4% ... Ciclopirox 8% / Fluconazole 1% / Terbinafine HCl 1% ... Canesoral Combi 1 Day …
Matched Products: … Fluconazol B. Braun 2 mg/ml Infusionslösung ... CANDIDIN 50 MG KAPSÜL, 3 ADET ... FLUCONAZOLO B. BRAUN …
Citrus bioflavonoids
Approved
Experimental
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Flavin adenine dinucleotide
A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972)
Flavin adenine dinucleotide is approved for use in Japan under the trade name Adeflavin as an ophthalmic treatment for vitamin B2 deficiency.
Approved
Matched Synonyms: … adenosine 5'-[3-(riboflavin-5'-yl) dihydrogen diphosphate] …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}[({[(2R,3S,4S)-5-{7,8-dimethyl …
Matched Description: … A condensation product of riboflavin and adenosine diphosphate. …
Matched Categories: … Vitamin B Complex ... Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}[({[(2R,3S,4S)-5-{7,8-dimethyl …
Matched Description: … A condensation product of riboflavin and adenosine diphosphate. …
Matched Categories: … Vitamin B Complex ... Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring …
Maftivimab
Ebola virus (EBOV) remains an important human pathogen within the Ebolavirus genus, having been responsible for at least 17 known outbreaks with an average case fatality rate of 43.92%. Immune therapy using monoclonal antibodies (mAbs) is becoming an increasingly attractive therapeutic method to combat infectious diseases due to its rapid...
Approved
Matched Description: … Ebola virus (EBOV) remains an important human pathogen within the _Ebolavirus_ genus, having been responsible ... All three mAbs bind to a distinct portion of the GP1,2 glycoprotein and collectively provide ... [A221825, A221830] A recent large-scale study elucidated that both neutralizing and Fc-mediated functions …
Matched Categories: … Treatments for Ebola Virus Disease …
Matched Categories: … Treatments for Ebola Virus Disease …
Disperse Blue 106
Disperse Blue 106 is used in allergenic testing.
Approved
Experimental
Matched Synonyms: … 5-Nitro-2-(2-methyl-4-(N-ethyl-N-(2-hydroxyethyl)amino)phenylazo)thiazole …
Matched Iupac: … 2-[ethyl({3-methyl-4-[(E)-2-(5-nitro-1,3-thiazol-2-yl)diazen-1-yl]phenyl})amino]ethan-1-ol …
Matched Iupac: … 2-[ethyl({3-methyl-4-[(E)-2-(5-nitro-1,3-thiazol-2-yl)diazen-1-yl]phenyl})amino]ethan-1-ol …
Atoltivimab
Ebola virus (EBOV) remains an important human pathogen within the Ebolavirus genus, having been responsible for at least 17 known outbreaks with an average case fatality rate of 43.92%. Immune therapy using monoclonal antibodies (mAbs) is becoming an increasingly attractive therapeutic method to combat infectious diseases due to its rapid...
Approved
Matched Description: … Ebola virus (EBOV) remains an important human pathogen within the _Ebolavirus_ genus, having been responsible ... All three mAbs bind to a distinct portion of the GP1,2 glycoprotein and collectively provide ... [A221825, A221830] A recent large-scale study elucidated that both neutralizing and Fc-mediated functions …
Matched Categories: … Treatments for Ebola Virus Disease …
Matched Categories: … Treatments for Ebola Virus Disease …
Bimatoprost
Bimatoprost, also known as Latisse or Lumigan, belongs to a group of drugs called prostamides, which are synthetic structural analogs of prostaglandin. Bimatoprost, marketed by Allergan, is administered in both the ophthalmic solution and implant form. It has the ability to reduce ocular hypotension, proving effective in conditions such as...
Approved
Investigational
Matched Synonyms: … (Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((1E,3S)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-5-heptenamide …
Matched Iupac: … (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl]-N-ethylhept …
Matched Description: … Bimatoprost, also known as Latisse or Lumigan, belongs to a group of drugs called prostamides, which ... 2001 for ocular hypertension and later approved for hypothrichosis in 2008, as eyelash growth became a …
Matched Mixtures name: … GANFORT % 0,03 + % 0,5 GÖZ DAMLASI, ÇÖZELTİ, 3 ML ... BEMATORİN-T 0,3 MG + 5 MG/1 ML GÖZ DAMLASI, ÇÖZELTİ, 1 ADET ... BİMASOPT %0.03+%0.5 GÖZ DAMLASI, ÇÖZELTİ, 1 ADET …
Matched Products: … BEMATORIN %0.03 GÖZ DAMLASI,3 ML ... LUMIGAN % 0,03 GÖZ DAMLASI, ÇÖZELTİ, 3 ML ... BIMAPRESS 0.3 GÖZ DAAMLASI, 1 ADET …
Matched Iupac: … (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl]-N-ethylhept …
Matched Description: … Bimatoprost, also known as Latisse or Lumigan, belongs to a group of drugs called prostamides, which ... 2001 for ocular hypertension and later approved for hypothrichosis in 2008, as eyelash growth became a …
Matched Mixtures name: … GANFORT % 0,03 + % 0,5 GÖZ DAMLASI, ÇÖZELTİ, 3 ML ... BEMATORİN-T 0,3 MG + 5 MG/1 ML GÖZ DAMLASI, ÇÖZELTİ, 1 ADET ... BİMASOPT %0.03+%0.5 GÖZ DAMLASI, ÇÖZELTİ, 1 ADET …
Matched Products: … BEMATORIN %0.03 GÖZ DAMLASI,3 ML ... LUMIGAN % 0,03 GÖZ DAMLASI, ÇÖZELTİ, 3 ML ... BIMAPRESS 0.3 GÖZ DAAMLASI, 1 ADET …
Autologous peripheral blood-derived CD34+ cells
Autologous peripheral blood-derived CD34+ cells, or CLBS119 (a proprietary version being developed by Caladrius Biosciences, Inc.), are hematopoietic stem cells. It is also a cell therapy being investigated by Caladrius Biosciences in the clinical trial NCT04522817 (CLBS119 for Repair of COVID-19 Induced Pulmonary Damage).
Approved
Investigational
Matched Description: … Autologous peripheral blood-derived CD34+ cells, or CLBS119 (a proprietary version being developed by ... [L27741] It is also a cell therapy being investigated by Caladrius Biosciences in the clinical trial …
Rimegepant
Rimegepant is an oral antagonist of the CGRP receptor developed by Biohaven Pharmaceuticals. It received FDA approval on February 27, 2020 for the acute treatment migraine headache, and was subsequently approved by the European Commission in April 2022 for both the treatment and prevention of migraines. While several parenteral antagonists...
Approved
Investigational
Matched Iupac: … [4,5-b]pyridin-1-yl}piperidine-1-carboxylate ... (5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-5H,6H,7H,8H,9H-cyclohepta[b]pyridin-9-yl 4-{2-oxo-1H,2H,3H-imidazo …
Matched Salts cas: … 1374024-48-2 …
Matched Categories: … MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring …
Matched Salts cas: … 1374024-48-2 …
Matched Categories: … MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring …
Ubrogepant
Ubrogepant is indicated for the acute treatment of migraine headaches with or without aura in adults. It was approved by the FDA on December 23, 2019, and is the first oral calcitonin gene-related peptide (CGRP) receptor antagonist approved for the acute treatment of migraine. Several oral small molecule CGRP receptor...
Approved
Investigational
Matched Iupac: … (6S)-N-[(3S,5S,6R)-6-methyl-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)piperidin-3-yl]-2'-oxo-1',2',5,7-tetrahydrospiro ... [cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-carboxamide …
Matched Description: … [L10926] It was approved by the FDA on December 23, 2019, and is the first oral calcitonin gene-related ... but limited by liver toxicity - this led to the development of ubrogepant, which was designed to be a ... [L10959] Several oral small molecule CGRP receptor antagonists, belonging to a class of medications referred …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Description: … [L10926] It was approved by the FDA on December 23, 2019, and is the first oral calcitonin gene-related ... but limited by liver toxicity - this led to the development of ubrogepant, which was designed to be a ... [L10959] Several oral small molecule CGRP receptor antagonists, belonging to a class of medications referred …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Ulmus americana pollen
Ulmus americana pollen is the pollen of the Ulmus americana plant. Ulmus americana pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 11 Tree Pollen Mix ... 11 Tree Pollen Mix ... 11 Tree Pollen Mix …
Doxorubicin
Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970.[A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a primary alcohol group compared to the methyl group of daunorubicin. Although its detailed...
Approved
Investigational
Matched Synonyms: … (1S,3S)-3-glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino ... -8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione ... (8S-cis)-10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy …
Matched Iupac: … )-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione ... (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-8-(2-hydroxyacetyl …
Matched Description: … Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius ... A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a ... A257614] Thanks to its efficacy and broad effect, doxorubicin was approved by the FDA in 1974 to treat a …
Matched Categories: … BSEP/ABCB11 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … CAELYX 2 MG/ML KONSANTRE İNFUZYON ÇÖZELTİSİ, 1 ADET ... DOXORRUBICINA CLORHIDRATO 50 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE. ... DOLNIX 2 MG /ML …
Matched Iupac: … )-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione ... (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-8-(2-hydroxyacetyl …
Matched Description: … Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius ... A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a ... A257614] Thanks to its efficacy and broad effect, doxorubicin was approved by the FDA in 1974 to treat a …
Matched Categories: … BSEP/ABCB11 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … CAELYX 2 MG/ML KONSANTRE İNFUZYON ÇÖZELTİSİ, 1 ADET ... DOXORRUBICINA CLORHIDRATO 50 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE. ... DOLNIX 2 MG /ML …
Magnesium acetate tetrahydrate
Magnesium acetate tetrahydrate is a hydrated form of anhydrous magnesium acetate salt with the chemical formula of Mg(CH3COO)2 • 4H2O. As a salt form of magnesium, magnesium acetate is one of the bioavailable forms of magnesium and forms a very water soluble compound. Magnesium is an essential element and second...
Approved
Matched Iupac: … magnesium(2+) ion diacetate tetrahydrate …
Matched Description: … formula of Mg(CH3COO)2 • 4H2O. ... a very water soluble compound. ... Magnesium acetate tetrahydrate is a hydrated form of anhydrous magnesium acetate salt with the chemical …
Matched Mixtures name: … Nutriflex Omega peri B. Braun Emulsion zur Infusion ... Nutriflex Omega plus B. Braun Emulsion zur Infusion ... Nutriflex Lipid peri B. Braun Emulsion zur Infusion …
Matched Description: … formula of Mg(CH3COO)2 • 4H2O. ... a very water soluble compound. ... Magnesium acetate tetrahydrate is a hydrated form of anhydrous magnesium acetate salt with the chemical …
Matched Mixtures name: … Nutriflex Omega peri B. Braun Emulsion zur Infusion ... Nutriflex Omega plus B. Braun Emulsion zur Infusion ... Nutriflex Lipid peri B. Braun Emulsion zur Infusion …
Abatacept
Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1).[L20504,L42715] Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it...
Approved
Matched Description: … antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin ... [L20504,L42715] Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight ... of 92,300 Da and it is a homodimer of two homologous polypeptide chains of 357 amino acids each. …
Remestemcel-L
Remestemcel-L is a third-party, off-the-shelf suspension of ex-vivo cultured adult human mesenchymal stem cells intended for intravenous infusion. The mesenchymal stem cells are derived from the bone marrow of unrelated and human leukocyte antigen (HLA)–unmatched healthy adult donors and have the ability to differentiate into different tissue cells. It was...
Approved
Investigational
Matched Description: … The mesenchymal stem cells are derived from the bone marrow of unrelated and human leukocyte antigen ... risk for poor outcomes and creating a significant clinical challenge [A31818]. ... Remestemcel-L is a third-party, off-the-shelf suspension of ex-vivo cultured adult human mesenchymal …
Dabrafenib
Dabrafenib mesylate (Tafinlar) is a reversible ATP-competitive kinase inhibitor and targets the MAPK pathway. It was approved on May 29, 2013, for the treatment of melanoma with V600E or V6000K mutation. It was also used for metastatic non-small cell lung cancer with the same mutation. In May 2018, Tafinlar (dabrafenib),...
Approved
Investigational
Matched Iupac: … N-{3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl}-2,6-difluorobenzene-1- …
Matched Description: … Dabrafenib mesylate (Tafinlar) is a reversible ATP-competitive kinase inhibitor and targets the MAPK ... [L41955] In May 2018, Tafinlar (dabrafenib), in combination with Mekinist ([DB08911]), was approved …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... B-Raf serine-threonine kinase (BRAF) inhibitors ... Organic Anion Transporter 1 Inhibitors ... Proto-Oncogene Proteins B-raf, antagonists & inhibitors ... P-glycoprotein substrates with a Narrow Therapeutic Index …
Matched Description: … Dabrafenib mesylate (Tafinlar) is a reversible ATP-competitive kinase inhibitor and targets the MAPK ... [L41955] In May 2018, Tafinlar (dabrafenib), in combination with Mekinist ([DB08911]), was approved …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... B-Raf serine-threonine kinase (BRAF) inhibitors ... Organic Anion Transporter 1 Inhibitors ... Proto-Oncogene Proteins B-raf, antagonists & inhibitors ... P-glycoprotein substrates with a Narrow Therapeutic Index …
Inonotus obliquus fruiting body
Inonotus obliquus fruiting body is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Description: … Inonotus obliquus fruiting body is a plant/plant extract used in some OTC (over-the-counter) products …
Chromium nicotinate
Approved
Experimental
Matched Iupac: … chromium(3+) tris(pyridine-3-carboxylate) …
Matched Mixtures name: … Omega-3 Rx Complete …
Matched Mixtures name: … Omega-3 Rx Complete …
Cabotegravir
Cabotegravir, or GSK1265744, is an HIV-1 integrase inhibitor that is prescribed with the non-nucleoside reverse transcriptase inhibitor, rilpivirine.[A227668,L31188,L31193] Early research into cabotegravir showed it had lower oral bioavailability than dolutegravir, which resulted in the development of long acting monthly intramuscular injection formulation for cabotegravir.[A227668,L31193]
Cabotegravir was granted FDA approval on...
Approved
Investigational
Matched Iupac: … (3R,6S)-N-[(2,4-difluorophenyl)methyl]-10-hydroxy-6-methyl-8,11-dioxo-4-oxa-1,7-diazatricyclo[7.4.0.0 …
Matched Description: … Cabotegravir, or GSK1265744, is an HIV-1 integrase inhibitor that is prescribed with the non-nucleoside ... Cabotegravir was granted FDA approval on 21 January 2021 in combination with rilpivirine to treat HIV-1 …
Matched Salts cas: … 1051375-13-3 …
Matched Categories: … Human Immunodeficiency Virus Integrase Strand Transfer Inhibitor ... Heterocyclic Compounds, 1-Ring ... Organic Anion Transporter 1 Inhibitors …
Matched Description: … Cabotegravir, or GSK1265744, is an HIV-1 integrase inhibitor that is prescribed with the non-nucleoside ... Cabotegravir was granted FDA approval on 21 January 2021 in combination with rilpivirine to treat HIV-1 …
Matched Salts cas: … 1051375-13-3 …
Matched Categories: … Human Immunodeficiency Virus Integrase Strand Transfer Inhibitor ... Heterocyclic Compounds, 1-Ring ... Organic Anion Transporter 1 Inhibitors …
Carthamus tinctorius flower bud
Carthamus tinctorius flower bud is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Description: … Carthamus tinctorius flower bud is a plant/plant extract used in some OTC (over-the-counter) products …
Benzylpenicilloyl polylysine
Benzylpenicilloyl polylysine is used as a skin-testing reagent to detect immunoglobulin E antibodies in people with a history of penicillin allergy. The quantitation of in vitro IgE antibodies to the benzylpenicilloyl determinant is a useful tool for evaluating allergic subjects.
Approved
Matched Description: … in people with a history of penicillin allergy. ... Benzylpenicilloyl polylysine is used as a skin-testing reagent to detect immunoglobulin E antibodies ... The quantitation of in vitro IgE antibodies to the benzylpenicilloyl determinant is a useful tool for …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Mirvetuximab soravtansine
Mirvetuximab soravtansine-gynx (IMGN853) is an antibody-drug conjugate (ADC) formed by a monoclonal antibody (M9346A) that targets folate receptor alpha (FRα), covalently joined by a cleavable disulfide linker to the genotoxic compound DM4 (also known as soravtansine or ravtansine).[A254392,L43967] DM4 is conjugated to the antibody with a drug-to-antibody ratio of 3.5:1....
Approved
Investigational
Matched Description: … [A254392,L43967] DM4 is conjugated to the antibody with a drug-to-antibody ratio of 3.5:1. ... 3 prior systemic treatment regimens. ... This decision was supported by findings from the phase 3 SORAYA trial (NCT04296890). …
Displaying drugs 576 - 600 of 6317 in total