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Displaying drugs 576 - 600 of 4801 in total

Somatrogon

Somatrogon is a long-acting recombinant human growth hormone. Growth hormone is a peptide hormone secreted by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and adolescence and regulating metabolic function in adulthood. Recombinant growth hormone therapy for growth hormone deficiency and other conditions has...
Approved
Matched Synonyms: … .)-(118-145)-PEPTIDE (1-28) WITH HUMAN SOMATOTROPIN (GROWTH HORMONE, GH) (29-219) AND TWO TANDEM COPIES …
Matched Description: … adolescence and regulating metabolic function in adulthood. ... of somatrogon and allows its once-weekly dosing. ... by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Anterior Pituitary Lobe Hormones and Analogues ... Sex Hormones and Insulins ... Somatropin and Somatropin Agonists …

Methadone

Methadone is a potent synthetic analgesic that works as a full µ-opioid receptor (MOR) agonist and N-methyl-d-aspartate (NMDA) receptor antagonist. As a full MOR agonist, methadone mimics the natural effects of the body's opioids, endorphins, and enkephalins through the release of neurotransmitters involved in pain transmission. It also has a...
Approved
Matched Synonyms: … 6-Dimethylamino-4,4-diphenyl-3-heptanone …
Matched Iupac: … 6-(dimethylamino)-4,4-diphenylheptan-3-one …
Matched Description: … of illicit opioids with the long-acting opioids used in OAT is to prevent withdrawal symptoms for 24-36 ... of serotonin and norepinephrine uptake. ... [hydromorphone], [oxycodone], and [fentanyl]. …
Matched Salts name: … Methadone hydrochloride …
Matched Products: … Methadone Hydrochloride ... Methadone hydrochloride ... Methadone Hydrocloride …

Phytic acid

Phytic acid is under investigation in clinical trial NCT01000233 (Value of Oral Phytate (InsP6) in the Prevention of Progression of the Cardiovascular Calcifications).
Investigational
Matched Synonyms: … Fytic acid ... Acido fitico ... Acide fytique …
Matched Name: … Phytic acid …
Matched Iupac: … {[(1s,2R,3R,4r,5S,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl]oxy}phosphonic acid …
Matched Description: … Phytic acid is under investigation in clinical trial NCT01000233 (Value of Oral Phytate (InsP6) in the …

Nepafenac

Nepafenac is a non-steroidal anti-inflammatory prodrug (NSAID) usually sold as a prescription eye drop. It is used to treat pain and inflammation associated with cataract surgery.
Approved
Investigational
Matched Synonyms: … 2-amino-3-benzoylbenzeneacetamide …
Matched Iupac: … 2-(2-amino-3-benzoylphenyl)acetamide …
Matched Description: … It is used to treat pain and inflammation associated with cataract surgery. …
Matched Categories: … Acids, Acyclic ... Acids, Carbocyclic ... Carboxylic Acids …
Matched Products: … NEVANAC 3 MG/ML GÖZ DAMLASI, SÜSPANSİYON ... NEVANAC %0,1 STERIL SUSPANSIYON GOZ DAMLASI, 5 ML …

Calcium gluconate

Calcium gluconate is used as mineral supplement and medication when there is insufficient calcium in the diet. Supplementation may be done to treat or prevent osteoporosis or rickets, consequences of hypocalcemia. It can also be taken by mouth but is not recommended by injection into a muscle. Calcium Gluconate Injection,...
Approved
Vet approved
Matched Synonyms: … D-gluconic acid, calcium salt (2:1) …
Matched Iupac: … calcium bis((2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate) …
Matched Description: … Hydrochloric acid and/or sodium hydroxide may have been added for pH adjustment (6.0 to 8.2). ... Calcium gluconate is used as mineral supplement and medication when there is insufficient calcium in ... Calcium saccharate provides 6% of the total calcium and stabilizes the supersaturated solution of calcium …
Matched Categories: … Acids, Acyclic ... Sugar Acids ... Hydroxy Acids ... Carboxylic Acids ... Alimentary Tract and Metabolism …
Matched Products: … HYDROFLUORIC ACID ANTIDOTE GEL 2.5% w/w …

gamma-carboxy-L-glutamic acid

Experimental
Matched Synonyms: … (3S)-3-amino-1,1,3-propanetricarboxylic acid ... γ-carboxy-L-glutamic acid ... gamma-Carboxyglutamic acid …
Matched Name: … gamma-carboxy-L-glutamic acid …
Matched Iupac: … (1S)-1-aminopropane-1,3,3-tricarboxylic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids …

Bumetanide

Bumetanide is a sulfamyl diuretic.
Approved
Matched Synonyms: … 3-butylamino-4-(phenoxy)-5-sulfamoylbenzoic acid ... 3-butylamino-4-phenoxy-5-sulfamoyl-benzoic acid ... 3-butylamino-4-phenoxy-5-sulfamoylbenzoic acid …
Matched Iupac: … 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Genito Urinary System and Sex Hormones ... bumetanide and potassium ... Gynecological Antiinfectives and Antiseptics …

Etidronic acid

Etidronic acid is a first generation bisphosphonate similar to clodronic acid and tiludronic acid. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate zoledronic acid, ibandronic acid,...
Approved
Matched Synonyms: … Etidronic acid ... acide étidronique ... acidum etidronicum …
Matched Name: … Etidronic acid …
Matched Iupac: … (1-hydroxy-1-phosphonoethyl)phosphonic acid …
Matched Description: … ], [ibandronic acid], [minodronic acid], and [risedronic acid]. ... Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid] ... A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and …
Matched Categories: … etidronic acid and calcium, sequential ... etidronic acid ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … DIDRONAT 400 MG TABLET, 30 ADET …

p-Coumaric acid

Experimental
Matched Synonyms: … (2E)-3-(4-hydroxyphenyl)acrylic acid ... (E)-3-(4-hydroxyphenyl)-2-propenoic acid ... 4-coumaric acid …
Matched Name: … p-Coumaric acid …
Matched Iupac: … (2E)-3-(4-hydroxyphenyl)prop-2-enoic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …

trans-urocanic acid

Experimental
Matched Synonyms: … (2E)-3-(1H-imidazol-4-yl)acrylic acid ... (E)-3-(1H-imidazol-4-yl)-2-propenoic acid ... Urocanic acid …
Matched Name: … trans-urocanic acid …
Matched Iupac: … (2E)-3-(1H-imidazol-4-yl)prop-2-enoic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …

Indoxyl sulfate

Experimental
Matched Synonyms: … 3-Indoxylsulfuric acid ... Indoxyl sulfic acid ... Indoxylsulfuric acid …
Matched Iupac: … (1H-indol-3-yl)oxidanesulfonic acid …

Sinapic acid

Sinapic acid is a matrix for matrix-assisted laser desorption technique for protein MW determination. It is also a constituent of propolis.
Experimental
Matched Synonyms: … (E)-3-(4-Hydroxy-3,5-dimethoxyphenyl)-2-propenoic acid ... Sinapinic acid ... trans-sinapic acid …
Matched Name: … Sinapic acid …
Matched Iupac: … (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoic acid …
Matched Description: … Sinapic acid is a matrix for matrix-assisted laser desorption technique for protein MW determination. …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic ... Indicators and Reagents …

Phenibut

Experimental
Matched Synonyms: … 4-amino-3-phenylbutyric acid …
Matched Iupac: … 4-amino-3-phenylbutanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids ... Hypnotics and Sedatives …

gamma-Hydroxybutyric acid

Gamma hydroxybutyric acid, commonly abbreviated GHB, is a therapeutic drug which is illegal in multiple countries. It is currently regulated in the US and sold by Jazz Pharmaceuticals under the name Xyrem. However, it is important to note that GHB is a designated Orphan drug (in 1985). Today Xyrem is...
Approved
Illicit
Investigational
Matched Synonyms: … 3-carboxypropoxy acid ... oxy-n-butyric acid ... 4-hydroxy-butyric acid …
Matched Name: … gamma-Hydroxybutyric acid …
Matched Iupac: … 4-hydroxybutanoic acid …
Matched Description: … Gamma hydroxybutyric acid, commonly abbreviated GHB, is a therapeutic drug which is illegal in multiple ... It is currently regulated in the US and sold by Jazz Pharmaceuticals under the name Xyrem. ... Today Xyrem is a Schedule III drug; however GHB remains a Schedule I drug and the illicit use of Xyrem …
Matched Categories: … Fatty Acids ... Fatty Acids, Volatile ... Acids, Acyclic ... Hydroxy Acids ... Carboxylic Acids …

trans-2-hydroxycinnamic acid

Experimental
Matched Synonyms: … (2E)-3-(2-hydroxyphenyl)-2-propenoic acid ... (2E)-3-(2-hydroxyphenyl)prop-2-enoic acid ... (E)-3-(2-Hydroxyphenyl)-2-propenoic acid …
Matched Name: … trans-2-hydroxycinnamic acid …
Matched Iupac: … (2E)-3-(2-hydroxyphenyl)prop-2-enoic acid …

3-Methylglutamic acid

Experimental
Matched Synonyms: … (3R)-3-methyl-L-glutamic acid ... (2S,3R)-2-azanyl-3-methyl-pentanedioic acid …
Matched Name: … 3-Methylglutamic acid …
Matched Iupac: … (2S,3R)-2-amino-3-methylpentanedioic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Excitatory Amino Acids ... Amino Acids, Dicarboxylic …

(3S)-3-methyl-D-aspartic acid

Experimental
Investigational
Matched Synonyms: … 3-methyl-beta-D-aspartic acid ... D-methyl aspartic acid …
Matched Name: … (3S)-3-methyl-D-aspartic acid …
Matched Iupac: … (2R,3S)-2-amino-3-methylbutanedioic acid …

Asparagine

A non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. It is biosynthesized from aspartic acid and ammonia by asparagine synthetase. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)
Approved
Investigational
Nutraceutical
Matched Synonyms: … (2S)-2-amino-3-carbamoylpropanoic acid ... (S)-2-amino-3-carbamoylpropanoic acid ... Aspartamic acid …
Matched Iupac: … (2S)-2-amino-3-carbamoylpropanoic acid …
Matched Description: … It is biosynthesized from aspartic acid and ammonia by asparagine synthetase. ... A non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain ... (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino ... Amino Acids, Neutral …

Sparfosic acid

Sparfosic acid is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at the terminal nitrogen atom. This substance is known to target aspartate carbamoyltransferase catalytic chain and CAD protein.
Experimental
Matched Synonyms: … Acidum sparfosicum ... Sparfosic acid ... N-(phosphonacetyl)-L-aspartic acid …
Matched Name: … Sparfosic acid …
Matched Iupac: … (2S)-2-(2-phosphonoacetamido)butanedioic acid …
Matched Description: … This substance is known to target aspartate carbamoyltransferase catalytic chain and CAD protein. ... Sparfosic acid is a solid. This compound belongs to the n-acyl-alpha amino acids. ... These are compounds containing an alpha amino acid which bears an acyl group at the terminal nitrogen …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids …

Aspartic acid

One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
Approved
Nutraceutical
Matched Synonyms: … Aspartic acid ... L-Aspartic acid ... Acidum asparticum …
Matched Name: … Aspartic acid …
Matched Iupac: … (2S)-2-aminobutanedioic acid …
Matched Description: … One of the non-essential amino acids commonly occurring in the L-form. ... It is found in animals and plants, especially in sugar cane and sugar beets. …
Matched Mixtures name: … Premasol - sulfite-free (Amino Acid) ... Premasol - sulfite-free (Amino Acid) ... PRIMENE 10% AMINO ACID INTRAVENOUS INFUSION …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Excitatory Amino Acids ... Amino Acids, Dicarboxylic …

Irinotecan

Irinotecan is a topoisomerase inhibitor used for chemotherapy. It is a water-soluble analogue of camptothecin, which is extracted from the Chinese tree Camptotheca acuminate. The bis-piperidine side chain in the structure of irinotecan bestows enhanced water solubility. As an anticancer drug, irinotecan was first commercially available in Japan in 1994...
Approved
Investigational
Matched Synonyms: … (S)-4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin ... -9-yl 4-(2-(5-(3-(2,4-dihydroxy-5-isopropylphenyl)-5-hydroxy-4H-1,2,4-triazol-4-yl)-1H-indol-1-yl)ethyl …
Matched Description: … Both irinotecan and SN-38 mediate antitumor activity by forming a complex with topoisomerase I and blocking ... This leads to the arrest of the cell cycle in the S-G2 phase and cancer cell death.[A263376] ... irinotecan was first commercially available in Japan in 1994 to treat various cancers such as lung, cervical and …
Matched Salts cas: … 136572-09-3 …
Matched Salts name: … Irinotecan hydrochloride ... Irinotecan hydrochloride hydrate …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … IRINOCAM 40 MG/2 ML IV PERFUZYON ICIN ENJEKTABL STERIL SOLUSYON ... IRINOCAM 100 MG/5 ML IV PERFUZYON ICIN ENJEKTABL STERIL SOLUSYON ... IRINOCAM 300 MG/15 ML IV PERFÜZYON İÇİN ÇÖZELTİ İÇEREN FLAKON …

Difenoxin

Difenoxin is a 4-phenylpiperidine which is closely related to the opioid analgesic meperidine. Difenoxin alone is a USA Schedule I controlled drug, as it may be habit forming. However, it is listed as a Schedule IV controlled drug if combined with atropine, which is added to decrease deliberate misuse. Motofen(R)...
Approved
Illicit
Matched Synonyms: … 1-(3-cyano-3,3-diphenylpropyl)-4-phenylisonipecotic acid ... Diphenoxilic acid ... Diphenoxylic acid …
Matched Iupac: … 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid …
Matched Description: … Motofen(R) is a brand mixture which combines atropine sulfate and difenoxin hydrochloride. ... It is approved by the FDA to treat acute and chronic diarrhea. ... It works mostly in the periphery and activates opioid receptors in the intestine rather than the central …
Matched Salts cas: … 35607-36-4 …
Matched Salts name: … Difenoxin hydrochloride …
Matched Categories: … Acids, Heterocyclic ... Isonipecotic Acids ... Alimentary Tract and Metabolism …

Nitrendipine

Nitrendipine is a calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
Approved
Investigational
Matched Synonyms: … 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ethyl methyl ester …
Matched Iupac: … 3-ethyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … It is an effective antihypertensive agent and differs from other calcium channel blockers in that it ... does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive. …
Matched Mixtures name: … ENEAS 10/20 MG TABLET, 30 ADET ... ENIT 10 MG/20 MG TABLET, 30 ADET …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents ... enalapril and nitrendipine …
Matched Products: … NITREN ACIS 20MG …

SGS-742

SGS-742 has been used in trials studying the treatment of Seizures and Metabolic Disease.
Investigational
Matched Synonyms: … 3-Aminopropyl-Butyl Phosphinic Acid ... (3-Aminopropyl)(n-butyl)phosphinic acid …
Matched Iupac: … (3-aminopropyl)(butyl)phosphinic acid …
Matched Description: … SGS-742 has been used in trials studying the treatment of Seizures and Metabolic Disease. …

Fluciclovine

Fluciclovine is under investigation in clinical trial NCT03036943 (Fluciclovine (18F) Imaging of Breast Cancer).
Investigational
Matched Synonyms: … Anti-1-amino-3-18F-fluorocyclobutane-1-carboxylic acid ... Cyclobutanecarboxylic acid, 1-amino-3-fluoro-, trans- …
Matched Iupac: … (1r,3r)-1-amino-3-fluorocyclobutane-1-carboxylic acid …
Displaying drugs 576 - 600 of 4801 in total