Displaying drugs 6026 - 6050 of 8282 in total
MK-1454
A synthetic cyclic dinucleotide (CDN) and agonist of stimulator of interferon genes protein (STING), with potential immunoactivating and antineoplastic activities. Upon intratumoral (IT) administration, STING agonist MK-1454 binds to STING and activates the STING pathway, which promotes IKK-related kinase TANK-binding kinase 1 (TBK1) signaling and activates nuclear factor-kappa B (NF-kB)...
Investigational
Matched Description: … A synthetic cyclic dinucleotide (CDN) and agonist of stimulator of interferon genes protein (STING), ... Specifically, expression of IFN-beta (IFNb) enhances the cross-presentation of tumor-associated antigens ... regulatory factor 3 (IRF3) in immune cells in the tumor microenvironment; this leads to the production of …
Adenosine-5'-Monophosphate Glucopyranosyl-Monophosphate Ester
Serves as the glycosyl donor for formation of bacterial glycogen, amylose in green algae, and amylopectin in higher plants. [PubChem]
Experimental
Matched Description: … Serves as the glycosyl donor for formation of bacterial glycogen, amylose in green algae, and amylopectin …
Streptolydigin
Streptolydigin is an antibiotic isolated from culture filtrates of Streptomyces lydicus. It is active against gram-postive bacteria except micrococci.
Experimental
Matched Description: … Streptolydigin is an antibiotic isolated from culture filtrates of Streptomyces lydicus. …
AZD-9684
AZD-9684 is the first member of a new anti-thrombotic class (CPU inhibitors). It is being developed by AstraZeneca.
Investigational
Matched Description: … AZD-9684 is the first member of a new anti-thrombotic class (CPU inhibitors). …
Erteberel
Erteberel is an estrogen receptor beta agonist that has been used in trials studying the treatment of Benign Prostatic Hyperplasia.
Experimental
Investigational
Matched Description: … Erteberel is an estrogen receptor beta agonist that has been used in trials studying the treatment of …
Sapanisertib
Sapanisertib has been used in trials studying the treatment of HCC, Solid Tumor, Gliosarcoma, Liver Cancer, and Glioblastoma, among others.
Investigational
Matched Description: … Sapanisertib has been used in trials studying the treatment of HCC, Solid Tumor, Gliosarcoma, Liver Cancer …
Lanopepden
Lanopepden has been used in trials studying the treatment of Pneumonia, Infections, Bacterial, Skin Diseases, Infectious, and Skin Infections, Bacterial.
Investigational
Matched Description: … Lanopepden has been used in trials studying the treatment of Pneumonia, Infections, Bacterial, Skin Diseases …
Lomibuvir
Lomibuvir has been used in trials studying the treatment of Chronic Hepatitis C Virus and Chronic Hepatitis C Virus Infection.
Investigational
Matched Description: … Lomibuvir has been used in trials studying the treatment of Chronic Hepatitis C Virus and Chronic Hepatitis …
BMS-986094
INX-08189 has been used in trials studying the treatment of Hepatitis C, HCV (Genotype 1), and Hepatitis C Virus.
Investigational
Matched Description: … INX-08189 has been used in trials studying the treatment of Hepatitis C, HCV (Genotype 1), and Hepatitis …
Rilotumumab
Rilotumumab has been investigated for the treatment of Cancer, Lung Cancer, Solid Tumors, Gastric Cancer, and Prostate Cancer, among others.
Investigational
Matched Description: … Rilotumumab has been investigated for the treatment of Cancer, Lung Cancer, Solid Tumors, Gastric Cancer …
GW-406381
GW-406381 has been used in trials studying the treatment of Pain, Trauma, Neurodynia, Dental Pain, and Hyperalgesia, among others.
Investigational
Matched Description: … GW-406381 has been used in trials studying the treatment of Pain, Trauma, Neurodynia, Dental Pain, and …
Elubrixin
Elubrixin has been used in trials studying the treatment of Cystic Fibrosis, Colitis, Ulcerative, and Chronic Obstructive Pulmonary Disease (COPD).
Investigational
Matched Description: … Elubrixin has been used in trials studying the treatment of Cystic Fibrosis, Colitis, Ulcerative, and …
ORE-1001
ORE1001 has been used in trials studying the treatment of Mild to Moderate Ulcerative Colitis. It is an ACE2 inhibitor.
Investigational
Matched Description: … ORE1001 has been used in trials studying the treatment of Mild to Moderate Ulcerative Colitis. …
Simendan
Simendan is under investigation in clinical trial NCT00527059 (Renal Effects of Levosimendan in Patients Admitted With Acute Decompensated Heart Failure).
Investigational
Matched Description: … Simendan is under investigation in clinical trial NCT00527059 (Renal Effects of Levosimendan in Patients …
Fletikumab
Fletikumab is under investigation in clinical trial NCT01038674 (Safety and Tolerability of Anti-IL-20 in Subjects With Rheumatoid Arthritis).
Investigational
Matched Description: … Fletikumab is under investigation in clinical trial NCT01038674 (Safety and Tolerability of Anti-IL-20 …
Soblidotin
Soblidotin has been used in trials studying the treatment of Sarcoma, Lung Cancer, and Unspecified Adult Solid Tumor, Protocol Specific.
Investigational
Matched Description: … Soblidotin has been used in trials studying the treatment of Sarcoma, Lung Cancer, and Unspecified Adult …
LTX-315
LTX-315 has been used in trials studying the treatment of Cancer, Lymphoma, Melanoma, Carcinoma, and Breast Cancer, among others.
Investigational
Matched Description: … LTX-315 has been used in trials studying the treatment of Cancer, Lymphoma, Melanoma, Carcinoma, and …
AQX-1125
AQX-1125 has been used in trials studying the treatment of COPD, Atopic Dermatitis, Interstitial Cystitis, and Bladder Pain Syndrome.
Investigational
Matched Description: … AQX-1125 has been used in trials studying the treatment of COPD, Atopic Dermatitis, Interstitial Cystitis …
1alpha-Hydroxyvitamin D5
1alpha-Hydroxyvitamin D5 (CARD-024) has been used in trials studying the treatment of Drug Safety and Heart; Disease, Activity.
Investigational
Matched Description: … 1alpha-Hydroxyvitamin D5 (CARD-024) has been used in trials studying the treatment of Drug Safety and …
Iomazenil
Iomazenil is under investigation in clinical trial NCT01590277 (Ability of Partial Inverse Agonist, Iomazenil, to Block Ethanol Effects in Humans).
Investigational
Matched Description: … Iomazenil is under investigation in clinical trial NCT01590277 (Ability of Partial Inverse Agonist, Iomazenil …
ITI-214
ITI-214 is under investigation in clinical trial NCT03489772 (Study of ITI-214 in Healthy Volunteers to Determine CNS Engagement).
Investigational
Matched Description: … ITI-214 is under investigation in clinical trial NCT03489772 (Study of ITI-214 in Healthy Volunteers …
AT-001
AT-001 is under investigation in clinical trial NCT03062384 (AT-001 for Long-term Preservation of Brain Health in Aging).
Investigational
Matched Description: … AT-001 is under investigation in clinical trial NCT03062384 (AT-001 for Long-term Preservation of Brain …
Pemafibrate
Pemafibrate is under investigation in clinical trial NCT03350165 (A Study of Pemafibrate in Patients With Nonalcoholic Fatty Liver Disease (NAFLD)).
Investigational
Matched Description: … Pemafibrate is under investigation in clinical trial NCT03350165 (A Study of Pemafibrate in Patients …
Avutometinib
Avutometinib (RO-5126766 free base) is under investigation in clinical trial NCT03875820 (Phase I Trial of VS-6063 and RO5126766.).
Investigational
Matched Description: … Avutometinib (RO-5126766 free base) is under investigation in clinical trial NCT03875820 (Phase I Trial of …
Gedivumab
Gedivumab is under investigation in clinical trial NCT01877785 (A Study of MHAA4549A to Assess Safety And Pharmacokinetics in Healthy Volunteers).
Investigational
Matched Description: … Gedivumab is under investigation in clinical trial NCT01877785 (A Study of MHAA4549A to Assess Safety …
Displaying drugs 6026 - 6050 of 8282 in total