Displaying drugs 601 - 625 of 985 in total
Dacarbazine
An antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564). Dacarbazine with Oblimersen is in clinical trials for the treatment of malignant melanoma.
Approved
Investigational
Matched Synonyms: … 4-(3,3-dimethyl-1-triazeno)imidazole-5-carboxamide ... 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide ... 4-(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Theobromine
Theobromine (3,7-dimethylxanthine) is the principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than theophylline and is also a less powerful stimulant of smooth muscle. It has practically no...
Investigational
Matched Synonyms: … 3,7-dihydro-3,7-dimethyl-1H-purine-2,6-dione …
Matched Iupac: … 3,7-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione …
Matched Description: … It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. ... A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. ... Theobromine (3,7-dimethylxanthine) is the principle alkaloid in Theobroma cacao (the cacao bean) and …
Matched Iupac: … 3,7-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione …
Matched Description: … It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. ... A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. ... Theobromine (3,7-dimethylxanthine) is the principle alkaloid in Theobroma cacao (the cacao bean) and …
YA-101
Investigational
Matched Synonyms: … 1h-benzimidazol-6-ol, 2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)- ... 2-[[(4-Methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazol-5-ol …
Seclidemstat
Investigational
Matched Synonyms: … N'-[(1E)-1-(5-chloro-2-hydroxyphenyl)ethylidene]- 3-(4-methylpiperazine-1-sulfonyl)benzohydrazide ... Benzoic acid, 3-((4-methyl-1-piperazinyl)sulfonyl)-, (2e)-2-(1-(5-chloro-2-hydroxyphenyl)ethylidene)hydrazide …
Matched Iupac: … N'-[(1E)-1-(5-chloro-2-hydroxyphenyl)ethylidene]-3-[(4-methylpiperazin-1-yl)sulfonyl]benzohydrazide …
Matched Iupac: … N'-[(1E)-1-(5-chloro-2-hydroxyphenyl)ethylidene]-3-[(4-methylpiperazin-1-yl)sulfonyl]benzohydrazide …
Hydroxycitronellal
Hydroxycitronellal is a synthetic fragrance that is widely used in many cosmetics and hygiene products such as deodorants, soaps, antiseptics, and other household items. It has the smell of lilac, lily, and lily of the valley . Hydroxycitronellal has also been shown to be a dermatologic irritant and allergen, and...
Approved
Experimental
Matched Synonyms: … 3,7-Dimethyl-7-hydroxyoctanal ... 3,7-dimethyl-7-hydroxyoctan-1-al …
Matched Description: … Hydroxycitronellal has also been shown to be a dermatologic irritant and allergen, and as a result commercially ... such as deodorants, soaps, antiseptics, and other household items. ... It has the smell of lilac, lily, and lily of the valley [A34269]. …
Matched Description: … Hydroxycitronellal has also been shown to be a dermatologic irritant and allergen, and as a result commercially ... such as deodorants, soaps, antiseptics, and other household items. ... It has the smell of lilac, lily, and lily of the valley [A34269]. …
Bezuclastinib
Investigational
Matched Synonyms: … 3,4-dimethyl-n-(2-phenyl-1h-pyrrolo(2,3-b)pyridin-5-yl)-1h-pyrazole-5-carboxamide ... 3,4-dimethyl-N-(2-phenyl-1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazole-5- carboxamide …
Matched Iupac: … 4,5-dimethyl-N-{2-phenyl-1H-pyrrolo[2,3-b]pyridin-5-yl}-1H-pyrazole-3-carboxamide …
Matched Iupac: … 4,5-dimethyl-N-{2-phenyl-1H-pyrrolo[2,3-b]pyridin-5-yl}-1H-pyrazole-3-carboxamide …
Chlorpromazine
The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class, chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking dopamine receptors. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
Approved
Investigational
Vet approved
Matched Synonyms: … 3-(2-chlorophenothiazin-10-yl)-N,N-dimethyl-propan-1-amine ... 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethyl-1-propanamine …
Matched Description: … Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the …
Matched Description: … Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the …
Ubidecarenone
Ubidecarenone, also called coenzyme Q10, is a 1,4-benzoquinone. From its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number of isoprenyl subunits in its tail. It is a powerful antioxidant, a lipid-soluble and essential cofactor in mitochondrial oxidative phosphorylation. The ubidecarenone is...
Approved
Investigational
Nutraceutical
Matched Description: … From its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number ... [A7874] It is a powerful antioxidant, a lipid-soluble and essential cofactor in mitochondrial oxidative ... [L1062] Ubidecarenone is sold as a dietary supplement and is not FDA approved as a drug - it is not meant …
Matched Mixtures name: … Vitamin E and Coq10 ... Co-q10 and Vitamin E ... Co-q10 M.R.B. 100mg and Vitamin E …
Matched Categories: … Enzymes and Coenzymes ... Diet, Food, and Nutrition …
Matched Products: … Coenzyme Q10 With Hawthorn Extract and Citrus Bioflavonoids …
Matched Mixtures name: … Vitamin E and Coq10 ... Co-q10 and Vitamin E ... Co-q10 M.R.B. 100mg and Vitamin E …
Matched Categories: … Enzymes and Coenzymes ... Diet, Food, and Nutrition …
Matched Products: … Coenzyme Q10 With Hawthorn Extract and Citrus Bioflavonoids …
TW-37
TW-37 is a small-molecule inhibitor of Bcl-2 investigated for its anti-cancer properties.
Investigational
Matched Synonyms: … Benzamide, n-(4-((2-(1,1-dimethylethyl)phenyl)sulfonyl)phenyl)-2,3,4-trihydroxy-5-((2-(1-methylethyl) ... N-(4-((2-(1,1-dimethylethyl)phenyl)sulfonyl)phenyl)-2,3,4-trihydroxy-5-((2-(1-methylethyl)phenyl)methyl ... N-[4-[[2-(1,1-Dimethylethyl)phenyl]sulfonyl]phenyl]-2,3,4-trihydroxy-5-[[2-(1-methylethyl)phenyl]methyl …
Venetoclax
Venetoclax is a BCL-2 inhibitor that was initially approved by the FDA in April 2016 [FDA label]. Proteins in the B cell CLL/lymphoma 2 (BCL-2) family are important regulators of the apoptotic (programmed cell death) process , . Venetoclax is used to treat chronic lymphocytic leukemia (CLL) and certain types...
Approved
Investigational
Matched Synonyms: … 4-{4-[(4'-chloro-5,5-dimethyl[3,4,5,6-tetrahydro[1,1'-biphenyl]]-2-yl)methyl]piperazin-1-yl}-N-(3-nitro ... -4-{[(oxan-4-yl)methyl]amino}benzene-1-sulfonyl)-2-[(1H-pyrrolo[2,3-b]pyridin-5-yl)oxy]benzamide ... dimethylcyclohex-1-en-1-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-((tetrahydro-2H-pyran-4-ylmethyl)amino)phenyl)sulfonyl …
Matched Description: … Venetoclax is used to treat chronic lymphocytic leukemia (CLL) and certain types of small lymphocytic …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Sulfones …
Matched Description: … Venetoclax is used to treat chronic lymphocytic leukemia (CLL) and certain types of small lymphocytic …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Sulfones …
Izuralimab
Izuralimab is under investigation in clinical trial NCT05879185 (A Study of Xmab23104 in People With Sarcoma).
Investigational
Matched Synonyms: … INDUCIBLE T-CELL COSTIMULATORY, ACTIVATION-INDUCIBLE LYMPHOCYTE IMMUNOMEDIATORY MOLECULE, AILIM, CD278)) AND …
(17beta)-17-(cyanomethyl)-2-methoxyestra-1(10),2,4-trien-3-yl sulfamate
Experimental
Matched Name: … (17beta)-17-(cyanomethyl)-2-methoxyestra-1(10),2,4-trien-3-yl sulfamate …
Matched Iupac: … cyanomethyl)-8-methoxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-yl sulfamate …
Matched Iupac: … cyanomethyl)-8-methoxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-yl sulfamate …
Oxygen
Oxygen is an element displayed by the symbol O, and atomic number 8. It is an essential element for human survival. Decreased oxygen levels may be treated with medical oxygen therapy. Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing blood flow...
Approved
Vet approved
Matched Description: … Oxygen is an element displayed by the symbol O, and atomic number 8. ... any disease that impairs the body's ability to take up and use gaseous oxygen. ... Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing …
Matched Mixtures name: … Carbon Dioxide and Oxygen Mixture, Compressed, Oxidizing, N.O.S. …
Matched Products: … OSSIGENO FARMA GAS MEDICAL AND TECHNICAL GASES …
Matched Mixtures name: … Carbon Dioxide and Oxygen Mixture, Compressed, Oxidizing, N.O.S. …
Matched Products: … OSSIGENO FARMA GAS MEDICAL AND TECHNICAL GASES …
1-Naphthylamine-5-sulfonic acid
Experimental
Matched Synonyms: … 5-Naphthylamine-1-sulfonic acid …
Matched Name: … 1-Naphthylamine-5-sulfonic acid …
Matched Iupac: … 5-aminonaphthalene-1-sulfonic acid …
Matched Categories: … Sulfonic Acids …
Matched Name: … 1-Naphthylamine-5-sulfonic acid …
Matched Iupac: … 5-aminonaphthalene-1-sulfonic acid …
Matched Categories: … Sulfonic Acids …
2-Naphthalenesulfonic acid
Experimental
Matched Synonyms: … Naphthalene-2-sulfonic acid …
Matched Iupac: … naphthalene-2-sulfonic acid …
Matched Categories: … Sulfonic Acids …
Matched Iupac: … naphthalene-2-sulfonic acid …
Matched Categories: … Sulfonic Acids …
ODM-207
Investigational
Matched Synonyms: … 2(1H)-Quinolinone, 6-(3,5-dimethyl-4-isoxazolyl)-7-methoxy-3-methyl-1-(2-pyridinylmethyl)- ... 6-(3,5-Dimethyl-4-isoxazolyl)-7-methoxy-3-methyl-1-(2-pyridinylmethyl)-2(1H)-quinolinone …
Bretylium
Bretylium blocks the release of noradrenaline from the peripheral sympathetic nervous system, and is used in emergency medicine, cardiology, and other specialties for the acute management of ventricular tachycardia and ventricular fibrillation. The primary mode of action for bretylium is thought to be inhibition of voltage-gated K(+) channels. Recent evidence...
Approved
Matched Synonyms: … N-ethyl-N,N-dimethyl-2-bromobenzenemethanaminium …
Matched Description: … tachycardia and ventricular fibrillation. ... Bretylium blocks the release of noradrenaline from the peripheral sympathetic nervous system, and is ... used in emergency medicine, cardiology, and other specialties for the acute management of ventricular …
Matched Mixtures name: … Bretylium Tosylate 0.4% and Dextrose 5% Inj ... Bretylium Tosylate 0.2% and Dextrose 5% Inj …
Matched Description: … tachycardia and ventricular fibrillation. ... Bretylium blocks the release of noradrenaline from the peripheral sympathetic nervous system, and is ... used in emergency medicine, cardiology, and other specialties for the acute management of ventricular …
Matched Mixtures name: … Bretylium Tosylate 0.4% and Dextrose 5% Inj ... Bretylium Tosylate 0.2% and Dextrose 5% Inj …
5-methoxy-N,N-dimethyltryptamine
5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a tryptamine with psychedelic properties. It is found in a wide variety of plant species, and a single psychoactive toad species, the Colorado River toad. This drug, as well as dimethyltryptamine and bufotenin, have been registered to be used in South America in religious and spiritual rituals.
Experimental
Illicit
Matched Synonyms: … N,N-dimethyl-5-methoxytryptamine ... 5-methoxy-N,N-dimethyl-1H-indole-3-ethanamine …
Matched Description: … America in religious and spiritual rituals. ... It is found in a wide variety of plant species, and a single psychoactive toad species, the Colorado ... This drug, as well as [dimethyltryptamine] and [bufotenin], have been registered to be used in South …
Matched Description: … America in religious and spiritual rituals. ... It is found in a wide variety of plant species, and a single psychoactive toad species, the Colorado ... This drug, as well as [dimethyltryptamine] and [bufotenin], have been registered to be used in South …
7,8-dihydro-7,7-dimethyl-6-hydroxypterin
Experimental
Matched Name: … 7,8-dihydro-7,7-dimethyl-6-hydroxypterin …
Matched Iupac: … 2-amino-7,7-dimethyl-1,4,5,6,7,8-hexahydropteridine-4,6-dione …
Matched Iupac: … 2-amino-7,7-dimethyl-1,4,5,6,7,8-hexahydropteridine-4,6-dione …
Edrophonium
A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
Approved
Matched Synonyms: … 3-hydroxy-N,N-dimethyl-N-ethylanilinium ... Ethyl-(3-hydroxy-phenyl)-dimethyl-ammonium …
Matched Description: … A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis …
Matched Description: … A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis …
Vadimezan
Investigational
Matched Synonyms: … (5,6-dimethyl-9-oxoxanthen-4-yl)acetic acid ... 5,6-Dimethyl-9-oxo-9H-xanthene-4-acetic acid …
Matched Iupac: … 2-(5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid …
Matched Iupac: … 2-(5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid …
Nilutamide
Nilutamide is an antineoplastic hormonal agent primarily used in the treatment of prostate cancer. Nilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors (but not for progestogen, estrogen, or glucocorticoid receptors). Consequently, Nilutamide blocks the action of androgens of adrenal and testicular origin that stimulate the growth of...
Approved
Investigational
Matched Synonyms: … 5,5-Dimethyl-3-(α,α,α-trifluoro-4-nitro-m-tolyl)hydantoin …
Matched Iupac: … 5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]imidazolidine-2,4-dione …
Matched Description: … the growth of normal and malignant prostatic tissue. ... Consequently, Nilutamide blocks the action of androgens of adrenal and testicular origin that stimulate ... Prostate cancer is mostly androgen-dependent and can be treated with surgical or chemical castration. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Iupac: … 5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]imidazolidine-2,4-dione …
Matched Description: … the growth of normal and malignant prostatic tissue. ... Consequently, Nilutamide blocks the action of androgens of adrenal and testicular origin that stimulate ... Prostate cancer is mostly androgen-dependent and can be treated with surgical or chemical castration. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
HEPES
Investigational
Matched Synonyms: … 4-(2-Hydroxyethyl)-1-piperazineethane sulfonic acid …
Matched Iupac: … 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethane-1-sulfonic acid …
Matched Categories: … Sulfonic Acids …
Matched Iupac: … 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethane-1-sulfonic acid …
Matched Categories: … Sulfonic Acids …
Displaying drugs 601 - 625 of 985 in total