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Displaying drugs 601 - 625 of 3040 in total

Sarilumab

Sarilumab is a fully human anti-interleukin 6 (IL-6) receptor monoclonal IgG1 antibody that binds to both membrane-bound and soluble IL-6 receptor forms, thus blocking the cis- and trans-inflammatory signalling cascades of IL-6. Sarilumab was developed by Sanofi and Regeneron Pharmaceuticals, Inc; it was US FDA-approved in May 2017 and followed...
Approved
Investigational
Matched Description: … Sarilumab is a fully human anti-interleukin 6 (IL-6) receptor monoclonal IgG1 antibody that binds to …
Matched Categories: … Interleukin Inhibitors ... Interleukin-6 Receptor Antagonist …

Diphenoxylate

A meperidine congener used as an antidiarrheal, usually in combination with atropine. At high doses, it acts like morphine. Its unesterified metabolite difenoxin has similar properties and is used similarly. It has little or no analgesic activity. This medication is classified as a Schedule V under the Controlled Substances Act...
Approved
Illicit
Matched Products: … LOMOTIL 2,5 MG/0.025 MG TABLET, 12 ADET …

Human Rho(D) immune globulin

Human Rho(D) immune globulin is a medicine given by intramuscular or intravenous injection that is used to prevent the immunological condition known as Rh disease (or hemolytic disease of newborn). Rho (D) immune globulin is available as a sterile, lyophilized or liquid gamma globulin (IgG) fraction containing antibodies to the...
Approved
Investigational
Matched Synonyms: … Human anti-D immunoglobulin ... Immunoglobulin human anti-RH ... Rho D immune globulin human …
Matched Name: … Human Rho(D) immune globulin …
Matched Description: … Human Rho(D) immune globulin is a medicine given by intramuscular or intravenous injection that is used ... Immune globullin was purified via ion-exchange chromatography method and prepared from pools of human …
Matched Categories: … Human Immunoglobulin G …

Siltuximab

Siltuximab is a chimeric (human-mouse) monoclonal immunoglobulin G1-kappa antibody produced in a Chinese hamster ovary (CHO) cell line by recombinant DNA technology. Siltuximab prevents the binding of IL-6 to soluble and membrane-bound IL-6 receptors by forming high affinity complexes with human interleukin-6 (IL-6). Its use is indicated for the treatment...
Approved
Investigational
Matched Description: … interleukin-6 (IL-6). ... hamster ovary (CHO) cell line by recombinant DNA technology. ... immunodeficiency virus (HIV) negative and human herpesvirus-8 (HHV-8) negative. …
Matched Categories: … Interleukin Inhibitors ... Interleukin-6 Antagonist …

Carbamoylcholine

Carbamoylcholine, also known as carbachol, is a muscarinic agonist discovered in 1932. Carbamoylcholine was initially used as a treatment for migraines, induction of diuresis, and other parasympathetic effects. Carbamoylcholine was granted FDA approval on 28 September 1972.
Approved
Matched Products: … MIOSTAT %0.01 İNTRAOKÜLER ÇÖZELTİ (12 ADET) …

Foreskin fibroblast (neonatal)

Foreskin fibroblast-like stromal cells (FDSCs) are progenitors isolated from human tissue that can differentiate into various cell types . Also known as Dermagraft, this device is a cryopreserved human fibroblast-derived dermal substitute. Composed of fibroblasts, extracellular matrix, and a bioabsorbable scaffold, it effectively supports wound healing . Dermagraft has only...
Approved
Matched Description: … Also known as Dermagraft, this device is a cryopreserved human fibroblast-derived dermal substitute. ... Foreskin fibroblast-like stromal cells (FDSCs) are progenitors isolated from human tissue that can differentiate ... Interestingly, it has been shown that human foreskin cells possess immunosuppressive properties, which …

Chloramphenicol

An antibiotic first isolated from cultures of Streptomyces venezuelae in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (From Martindale, The Extra Pharmacopoeia, 29th ed, p106)...
Approved
Vet approved
Withdrawn
Matched Products: … KLORA KAPSÜL, 12 ADET ... FENIKOL 250 MG KAPSÜL, 12 ADET ... SENTOKLORİN DRAJE 250 MG, 12 ADET …

Silver

Silver (Ag) is a chemical element that belongs in the family of transition metals in the periodic table. It has a high electrical conductivity, thermal conductivity, and reflectivity. Silver exists as a pure elemental form, alloy with other metals, and mineral. Having critical roles in various applications inducing chemical and...
Approved
Investigational

Risedronic acid

Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Investigational
Matched Mixtures name: … RISEPLUS D3 35 MG/2800 IU EFERVESAN TABLET, 12 ADET ... RISEPLUS D3 35 MG/5600 IU EFERVESAN TABLET, 12 ADET …
Matched Products: … ACARA 35MG DUO VITD3 12+72 ... ACARA 35MG TR CA&VITD3 12+ ... ACTEDAY 35 MG FILM KAPLI TABLET, 12 ADET …

Sulpiride

Sulpiride first appeared in published literature in 1967. Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather than positive symptoms at low doses, though the effects are more equal at higher doses. Sulpiride is not approved by the FDA, Health Canada, or the EMA; though...
Approved
Investigational
Matched Products: … DOLPIRID 200 MG TABLET, 12 ADET ... DOGMATIL 200 MG TABLET, 12 ADET …

Methoxsalen

A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA adducts in the presence of ultraviolet A irradiation.
Approved
Matched Products: … UVADEX 20 MG/ML STERIL SOLUSYON ICEREN FLAKON, 12 ADET …

Idursulfase

Idursulfase is a purified form of human iduronate-2-sulfatase, a lysosomal enzyme. Idursulfase is produced by recombinant DNA technology in a human cell line. Idursulfase is an enzyme that hydrolyzes the 2-sulfate esters of terminal iduronate sulfate residues from the glycosaminoglycans dermatan sulfate and heparan sulfate in the lysosomes of various...
Approved
Matched Description: … Idursulfase is produced by recombinant DNA technology in a human cell line. ... Idursulfase is a purified form of human iduronate-2-sulfatase, a lysosomal enzyme. …

Brodalumab

Brodalumab has been used in trials studying the treatment of Asthma, Psoriasis, Crohn's Disease, Psoriatic Arthritis, and Rheumatoid Arthritis. Brodalumab was FDA approved in February, 2017 as Siliq for the treatment of moderate-to-severe plaque psoriasis.
Approved
Investigational
Matched Categories: … Interleukin Inhibitors ... Receptors, Interleukin-17 ... Interleukin-17 Receptor A Antagonist ... Interleukin 17 Receptor A Antagonists …

Canakinumab

Canakinumab is a recombinant, human anti-human-IL-1β monoclonal antibody that belongs to the IgG1/κ isotype subclass. It is expressed in a murine Sp2/0-Ag14 cell line and comprised of two 447- (or 448-) residue heavy chains and two 214-residue light chains, with a molecular mass of 145157 Daltons when deglycosylated. Both heavy...
Approved
Investigational
Matched Description: … Canakinumab is a recombinant, human anti-human-IL-1β monoclonal antibody that belongs to the IgG1/κ isotype ... Canakinumab binds to human IL-1β and neutralizes its inflammatory activity by blocking its interaction ... weeks to be safe and effective, offering a considerable advantage over the existing treatment with the human …
Matched Categories: … Interleukin Inhibitors ... Interleukin-1 Blockers ... Interleukin-1β Blockers ... Interleukin-1beta, antagonists & inhibitors …

Peginterferon alfa-2a

Peginterferon alfa-2a is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Investigational
Matched Description: … Peginterferon alfa-2a is derived from the alfa-2a moeity of recombinant human interferon and acts by ... binding to human type 1 interferon receptors. ... Peginterferon alfa-2a is a form of recombinant interferon used as part of combination therapy to treat …

Imdevimab

Imdevimab is a monoclonal antibody combined with casirivimab in Regeneron's antibody cocktail known as REGEN-COV2 for the treatment of COVID-19. This drug is a combination of antibodies derived from humanized VelocImmune® mice in addition to blood samples from patients who have recovered from COVID-19. These antibodies have been formulated to...
Approved
Experimental
Matched Description: … Casirivimab and imdevimab are investigational recombinant human IgG1 monoclonal antibodies that, at this ... FDA authorized emergency approval of REGN-COV2 to treat mild to moderate COVID-19 in patients aged 12 …

Benralizumab

Benralizumab is a humanized recombinant monoclonal antibody of the isotype IgG1k immunoglobulin that specifically binds to the alpha chain of the interleukin 5 receptor (IL-5R) expressed on eosinophils and basophils. It inhibits the binding of IL-5 as well as the hetero-oligomerization of the alpha and beta subunits of the IL-5R,...
Approved
Investigational
Matched Description: … Benralizumab is a humanized recombinant monoclonal antibody of the isotype IgG1k immunoglobulin that ... specifically binds to the alpha chain of the interleukin 5 receptor (IL-5R) expressed on eosinophils …
Matched Categories: … Interleukin Antagonists ... Interleukin-5 Receptor alpha-directed Cytolytic Antibody ... Interleukin 5 Receptor alpha-directed Antibody Interactions …

Panitumumab

Panitumumab (ABX-EGF) is a recombinant human IgG2 monoclonal antibody that binds specifically to the human epidermal growth factor receptor (EGFR). This drug is an antineoplastic agent. Panitumumab was granted FDA approval on 27 September 2006.
Approved
Investigational
Matched Description: … Panitumumab (ABX-EGF) is a recombinant human IgG2 monoclonal antibody that binds specifically to the ... human epidermal growth factor receptor (EGFR). …

Simoctocog alfa

Simoctocog alfa is a recombinant B-domain deleted (BDD) rFVIII produced in genetically modified human embryonic kidney (HEK) 293F cells. The harvested product is concentrated and purified by a series of chromatography steps. It is an antihemorrhagic agent used as a replacement therapy in individuals with Haemophilia A who lack the...
Approved
Matched Description: … Simoctocog alfa is a recombinant B-domain deleted (BDD) rFVIII produced in genetically modified human ... Full human post-translational modifications via elimination of potentially immunogenic glycosylation ... patterns found in non-human cell lines led to decreased immunogenicity and longer half-life [A31525]. …

Cupric Chloride

Cupric chloride, for injection, is a sterile, nonpyrogenic solution intended for use as an additive to solutions for Total Parenteral Nutrition (TPN).
Approved
Investigational

Nicotine

Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
Approved
Matched Products: … NICORETTE FRESHMINT 2 MG NANELI SAKIZ, 12 ADET ... NICORETTE FRESHMINT 4 MG NANELI SAKIZ, 12 ADET ... NICORETTE FRESHFRUIT 2 MG MEYVELI SAKIZ, 12 ADET …

Ioflupane I-123

Ioflupane (I-123) is a radiopharmaceutical used to image dopamine neurons and diagnose Parkinsonian syndromes.
Approved

Brexanolone

As of March 2019, brexanolone - developed and made available commercially by Sage Therapeutics Inc. as the brand name product Zulresso - is the first drug to have ever been approved by the US FDA specifically for the treatment of postpartum depression (PPD) in adult females . Since PPD, like...
Approved
Investigational

Somatrem

Despite the ability of almost all contemporary recombinant growth hormones to cause definite and demonstrable increases in growth rate in patients who are administered the drug, the use of these agents continues to be mired in persistent bioethical debate . Such discussion revolves around whether patients' natural disposition of short...
Approved
Investigational
Withdrawn
Matched Description: … Despite the ability of almost all contemporary recombinant growth hormones to cause definite and demonstrable …

Etranacogene dezaparvovec

Hemophilia B - also called factor IX deficiency or Christmas disease - is an X-linked genetic disorder resulting in an absence or deficiency of clotting factor IX. Clotting factors, including factor IX, are necessary components of the signaling cascade responsible for blood clotting and subsequent wound healing. Symptoms of hemophilia...
Approved
Investigational
Matched Description: … [L44161] Treatment of hemophilia B primarily involves the routine replacement of factor IX using recombinant ... [L44186] In December 2022, the EMA's Committee for Medicinal Products for Human Use (CHMP) recommended ... of a viral vector carrying a codon-optimized DNA sequence of the gain-of-function Padua variant of human …
Displaying drugs 601 - 625 of 3040 in total