Displaying drugs 6326 - 6350 of 8178 in total
Livoletide
Livoletide is under investigation in clinical trial NCT03790865 (Effects of Livoletide (AZP-531) on Food-related Behaviors in Patients With Prader-Willi Syndrome).
Investigational
Matched Description: … Livoletide is under investigation in clinical trial NCT03790865 (Effects of Livoletide (AZP-531) on Food-related …
Chlorotoxin
Chlorotoxin is under investigation in clinical trial NCT00733798 (A Safety and Efficacy Study of Intravenous 131I-TM601 in Adult Patients With Malignant Melanoma).
Investigational
Matched Description: … Chlorotoxin is under investigation in clinical trial NCT00733798 (A Safety and Efficacy Study of Intravenous …
Tirabrutinib
Tirabrutinib is under investigation in clinical trial NCT02626026 (Safety and Pharmacokinetics of GS-4059 in Healthy Volunteers and Subjects With Rheumatoid Arthritis (RA)).
Investigational
Matched Description: … Tirabrutinib is under investigation in clinical trial NCT02626026 (Safety and Pharmacokinetics of GS- …
Panobacumab
Panobacumab is under investigation in clinical trial NCT00851435 (Safety and Pharmacokinetics of KBPA-101 in Hospital Acquired Pneumonia Caused by O11 Pseudomonas Aeruginosa).
Investigational
Matched Description: … Panobacumab is under investigation in clinical trial NCT00851435 (Safety and Pharmacokinetics of KBPA …
Nanatinostat
Nanatinostat is under investigation in clinical trial NCT00697879 (Safety Study of the Histone Deacetylase Inhibitor, CHR-3996, in Patients With Advanced Solid Tumours).
Investigational
Matched Description: … Nanatinostat is under investigation in clinical trial NCT00697879 (Safety Study of the Histone Deacetylase …
REC-994
REC-994 was cleared by the FDA in July, 2018 for a phase I trial for the treatment of cerebral cavernous malformation (CCM).
Investigational
Matched Description: … REC-994 was cleared by the FDA in July, 2018 for a phase I trial for the treatment of cerebral cavernous …
Levophencynonate
Levophencynonate is under investigation in clinical trial NCT02299804 (A Clinical Trial to Evaluate Efficacy and Safety of Levophencynonate Hydrochloride in Patient With Vertigo).
Investigational
Matched Description: … under investigation in clinical trial NCT02299804 (A Clinical Trial to Evaluate Efficacy and Safety of …
4'-Thio-fac
4'-Thio-fac is under investigation in clinical trial NCT02661542 (Study of FF-10502-01 in Patients With Advanced Solid Tumors and Lymphomas).
Investigational
Matched Description: … 4'-Thio-fac is under investigation in clinical trial NCT02661542 (Study of FF-10502-01 in Patients With …
EMB-01
EMB-01 is under investigation in clinical trial NCT03797391 (A Dose Escalation Study of EMB-01 in Participants With Advanced/metastatic Solid Tumors).
Investigational
Matched Description: … EMB-01 is under investigation in clinical trial NCT03797391 (A Dose Escalation Study of EMB-01 in Participants …
Dotinurad
Dotinurad is under investigation in clinical trial NCT03372200 (Febuxostat-controlled, Double-blind, Comparative Study of FYU-981 in Hyperuricemia With or Without Gout).
Investigational
Matched Description: … investigation in clinical trial NCT03372200 (Febuxostat-controlled, Double-blind, Comparative Study of …
Firsocostat
Firsocostat is under investigation in clinical trial NCT02781584 (Safety, Tolerability, and Efficacy of Selonsertib, Firsocostat, and Cilofexor in Adults With Nonalcoholic Steatohepatitis (NASH)).
Investigational
Matched Description: … Firsocostat is under investigation in clinical trial NCT02781584 (Safety, Tolerability, and Efficacy of …
Ivuxolimab
Ivuxolimab is under investigation in clinical trial NCT02554812 (A Study of Avelumab in Combination With Other Cancer Immunotherapies in Advanced Malignancies (JAVELIN Medley)).
Investigational
Matched Description: … Ivuxolimab is under investigation in clinical trial NCT02554812 (A Study of Avelumab in Combination With …
Orticumab
Orticumab is under investigation in clinical trial NCT04776629 (A Proof-of-activity Study With Orticumab in Subjects With Psoriasis and Cardiometabolic Risk Factors).
Investigational
Matched Description: … Orticumab is under investigation in clinical trial NCT04776629 (A Proof-of-activity Study With Orticumab …
Tividenofusp alfa
Tividenofusp alfa, also known as DNL-310, is a brain-penetrant enzyme replacement therapy being investigated for the treatment of Hunter syndrome.
Investigational
Matched Description: … known as DNL-310, is a brain-penetrant enzyme replacement therapy being investigated for the treatment of …
Aphidicolin
Aphidicolin is an antimitotic and antiviral metabolite of the mould Cephalosporium aphidicola. It inhibits DNA polymerase alpha and blocks DNA replication.[A259157, A259162]
Investigational
Matched Description: … Aphidicolin is an antimitotic and antiviral metabolite of the mould _Cephalosporium aphidicola_. …
TRK-001
TRK-001 is an autologous regulatory T-cell therapy. It is being investigated for the prevention of graft rejection following solid organ transplantation.
Investigational
Matched Description: … It is being investigated for the prevention of graft rejection following solid organ transplantation. …
ADL-5859
ADL-5859 is under investigation in clinical trial NCT00626275 (Study Evaluating the Analgesic Efficacy and Safety of ADL5859 in Participants With Rheumatoid Arthritis).
Investigational
Matched Description: … under investigation in clinical trial NCT00626275 (Study Evaluating the Analgesic Efficacy and Safety of …
Semzuvolimab
Semzuvolimab is under investigation in clinical trial NCT03149211 (To Investigate the Efficacy and Safety of UB-421 Monotherapy in HIV-1 Infected Adults).
Investigational
Matched Description: … Semzuvolimab is under investigation in clinical trial NCT03149211 (To Investigate the Efficacy and Safety of …
Frexalimab
Frexalimab is under investigation in clinical trial NCT06141486 (Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary Progressive Multiple Sclerosis).
Investigational
Matched Description: … Frexalimab is under investigation in clinical trial NCT06141486 (Efficacy and Safety Study of Frexalimab …
Sunobinop
Sunobinop is under investigation in clinical trial NCT04035200 (Safety, Tolerability and Efficacy Study of V117957 in Subjects With Insomnia Associated With Alcohol Cessation).
Investigational
Matched Description: … Sunobinop is under investigation in clinical trial NCT04035200 (Safety, Tolerability and Efficacy Study of …
Rimiducid
Rimiducid is a lipid-permeable tacrolimus analogue and a protein dimerizer. It was designed to overcome limitations of current cellular immunotherapies used for cancer and other blood disorders by enhancing the control of the immune cell activity and function. When administered via chemically-inducible dimerization (CID) technologies, rimiducid binds to switch proteins...
Investigational
Matched Description: … blood disorders by enhancing the control of the immune cell activity and function. ... It was designed to overcome limitations of current cellular immunotherapies used for cancer and other ... [A187496,L9521] The combination use of rimiducid with immunotherapies for enhanced therapeutic effectiveness …
Tyramine
Tyramine (4-hydroxyphenethylamine; para-tyramine, mydrial or uteramin) is a naturally occurring monoamine compound and trace amine derived from the amino acid tyrosine. Tyramine acts by inducing the release of catecholamine. An important characteristic of this product is its impediment to cross the blood-brain barrier which restrains its side effects to only...
Investigational
Nutraceutical
Matched Description: … Tyramine acts by inducing the release of catecholamine. ... An important characteristic of this product is its impediment to cross the blood-brain barrier which ... There have been reports of hypertensive crisis in patients ingesting tyramine-rich diet in conjunction …
Paquinimod
Paquinimod is developed for the treatment of SLE (Systemic Lupus Erythematosus), which is an autoimmune disease. The disease affects mainly women of fertile age and progresses in flares with relatively symptom free periods in between. Current treatments of SLE are NSAID (nonsteroidal anti-inflammatory drugs), corticosteroids, antimalarians or cytotoxic drugs like...
Investigational
Matched Description: … Paquinimod is developed for the treatment of SLE (Systemic Lupus Erythematosus), which is an autoimmune ... The disease affects mainly women of fertile age and progresses in flares with relatively symptom free ... Current treatments of SLE are NSAID (nonsteroidal anti-inflammatory drugs), corticosteroids, antimalarians …
Theobromine
Theobromine (3,7-dimethylxanthine) is the principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than theophylline and is also a less powerful stimulant of smooth muscle. It has practically no...
Investigational
Matched Description: … It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. ... It has a weaker diuretic activity than theophylline and is also a less powerful stimulant of smooth muscle …
XL820
XL820 is investigated for use/treatment in solid tumors. XL820 is a solid. The proteins that XL820 inhibit include platelet-derived growth factor receptor beta (PDGFR), mast/stem cell growth factor receptor KIT, vascular endothelial growth factor receptor 2, and platelet-derived growth factor receptor alpha, clinically validated targets implicated in a variety of...
Investigational
Matched Description: … XL820 exhibits dose-dependent growth inhibition in models of breast carcinoma, gliomas and leukemia. ... platelet-derived growth factor receptor alpha, clinically validated targets implicated in a variety of …
Displaying drugs 6326 - 6350 of 8178 in total