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Displaying drugs 626 - 650 of 848 in total

Clervonafusp alfa

Investigational
Matched Synonyms: … -glucosidase (human recombinant), disulfide with humanized monoclonal 3e10 .kappa.-chain ... Immunoglobulin g1, (humanized monoclonal 3e10 .gamma.1-chain fab fragment) fusion protein with 67-952 ... cell-penetrating humanized fab fragment targeting the equilibrative nucleoside transporter 2 (ent2), fused with …

Cyclobenzaprine

Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961 and has been available for human use since 1977. It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from Amitriptyline by only a single double bond.[A185039,A184982] Since its approval, it has...
Approved
Matched Description: … Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961[A185039] and has been …
Matched Products: … Comfort Pac With Cyclobenzaprine …

Vibrio cholerae Inaba 48 classical biotype, heat inactivated

Approved
Matched Name: … Vibrio cholerae Inaba 48 classical biotype, heat inactivated …
Matched Mixtures name: … DUKORAL VACCINE AGAINST CHOLERA AND ETEC-DIARRHOEA …

Sotatercept

Sotatercept is an activin signalling inhibitor. It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. On March 26, 2024, sotatercept was approved by the FDA for the treatment of pulmonary arterial hypertension...
Approved
Investigational
Matched Synonyms: … ACTIVIN RECEPTOR TYPE IIA (SYNTHETIC HUMAN EXTRACELLULAR DOMAIN-CONTAINING FRAGMENT) FUSION PROTEIN WITH ... IMMUNOGLOBULIN G1 (SYNTHETIC HUMAN HEAVY CHAIN FC FRAGMENT), DIMER ... HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN HEAVY …
Matched Description: … [L50361] Sotatercept works to resolve the imbalance in activin–growth differentiation factor and BMP …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Povidone

Povidone, also known as polyvinylpyrrolidone (PVP) or polyvidone, is a synthetic water-soluble polymer made from the monomer N-vinylpyrrolidone used as a binder in many pharmaceutical tablets and lubricant in eye drops. It is also used in many technical applications with various roles as an adhesive, additive, and emulsifier. When in...
Approved
Withdrawn
Matched Description: … It is also used in many technical applications with various roles as an adhesive, additive, and emulsifier ... component, mainly contributes to this effect, and povidone acts as a carrier [A32988]. ... water-soluble polymer made from the monomer N-vinylpyrrolidone used as a binder in many pharmaceutical tablets and …
Matched Mixtures name: … Rohto Sun and Sport ... Redness reliever and Lubricant ... Meijer Advanced Redness and Irritation Relief …
Matched Products: … iVizia Lubricant Eye for Severe Night Dry Eyes …

Mecbotamab vedotin

Mecbotamab vedotin is an anti-Axl humanized monoclonal antibody conjugated to monomethyl auristatin E using a cleavable linker (CAB-Axl-ADC).
Investigational
Matched Synonyms: … -CHAIN, DIMER, THIOETHER WITH N-(((4-((N-(6-(3-MERCAPTO-2,5-DIOXO ... HUMAN TYROSINE KINASE RECEPTOR AXL) (HUMAN-MUS MUSCULUS MONOCLONAL BA301 .GAMMA.1-CHAIN), DISULFIDE WITH …

P-BCMA-101

P-BCMA-101 is an autologous CAR-T therapy developed using Poseida’s piggyBac platform technology.
Investigational
Matched Synonyms: … Autologous T-cells transfected with PiggyBac transposon plasmid vector expressing B-cell maturation antigen …

Hepatitis B Vaccine (Recombinant)

Hepatitis B Vaccine is an ingredient in the EMA-withdrawn product Quintanrix. It is marketed in Canada as Engerix B. It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada. The hepatitis B virus induces a severe form of viral hepatitis. Other causative agents are hepatitis...
Approved
Withdrawn
Matched Description: … lifetime (mostly young adults); between 5% and 10% of infections lead to persistent viremia (carrier ... Carriers are at a high risk of developing chronic liver disease which may lead to cirrhosis or primary ... Transmission of the virus occurs through percutaneous contact with contaminated blood, serum or plasma …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Bacterial and viral vaccines, combined ... haemophilus influenzae B and hepatitis B …
Matched Products: … Recombivax HB (with Preservative) ... Recombivax HB (adult Dialysis With Preservative) …

Nacystelyn

Investigational
Matched Synonyms: … L-lysine, compd. with n-acetyl-l-cysteine …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Nicardipine

A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents. [PubChem]
Approved
Investigational
Matched Description: … It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents ... It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without ... A potent calcium channel blockader with marked vasodilator action. …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Selective Calcium Channel Blockers With Mainly Vascular Effects …
Matched Products: … VERDIF …

Adipose-Derived Mesenchymal Stem Cells: Autologous or Allogeneic Origins

Adipose mesenchymal stem cells (AMSCs) are MSCs derived from adipose tissue, which is more accessible and less painful than stem cells extracted from most other sources. Autologous stem cells are those derived from a patient’s own cells while allogeneic stem cells are derived from that of a donor. Lipoaspiration, also...
Investigational
Matched Name: … Adipose-Derived Mesenchymal Stem Cells: Autologous or Allogeneic Origins …
Matched Description: … and less painful than stem cells extracted from most other sources. ... bone, muscle, neural, and chondrocyte. ... This is followed by purification and expansion of the cells in vitro. …

Atracurium besylate

A non-depolarizing neuromuscular blocking agent with short duration of action. Its lack of significant cardiovascular effects and its lack of dependence on good kidney function for elimination provide clinical advantage over alternate non-depolarizing neuromuscular blocking agents.
Approved
Matched Description: … Its lack of significant cardiovascular effects and its lack of dependence on good kidney function for ... A non-depolarizing neuromuscular blocking agent with short duration of action. …
Matched Products: … Atracurium - (for Multiple Dose Vial - With Preservative) …

Neomycin

Neomycin is a broad-spectrum aminoglycoside antibiotic drug that is derived from the metabolic products of Streptomyces fradiae. Neomycin is a complex comprised of three components, neomycin A, B, and C. Neomycin B, also known as framycetin, is the most active component of the complex and neomycin C is the isomer...
Approved
Vet approved
Matched Description: … [L11979] It is also used in combination with [polymyxin B] sulfates and [hydrocortisone] in otic suspensions ... [L10532] Neomycin is also used in combination with [polymyxin B] sulfates and [dexamethasone] in ophthalmic ... [A175042] Neomycin is active against both gram-positive and gram-negative organisms and mediates its …
Matched Mixtures name: … CVS Health Triple Antibiotic with Pain Relief ... health and .beyond Triple Antibiotic ... CVS Health Medication and Topical Refill Pouch …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Antiinfectives and Antiseptics for Local Oral Treatment …
Matched Products: … Single Antibiotic with Neomycin …

Hexylresorcinol

Hexylresorcinol is a substituted dihydroxybenzene. It exhibits antiseptic, anthelmintic, and local anesthetic properties. It can be found in topical applications for minor skin infections and in oral solutions or throat lozenges for pain relief and first aid antiseptic. The compound may also be used commonly in various commercial cosmetic anti-aging...
Approved
Matched Description: … for pain relief and first aid antiseptic. ... It exhibits antiseptic, anthelmintic, and local anesthetic properties. ... It can be found in topical applications for minor skin infections and in oral solutions or throat lozenges …
Matched Products: … Antiseptic Throat Lozenges (with Hexylresorcinol) …

Fluvoxamine

Fluvoxamine is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor. Though it is in the same class as other SSRI drugs, it is most often used to treat obsessive-compulsive disorder. Fluvoxamine has been in use in clinical practice since 1983 and has a clinical trial database comprised...
Approved
Investigational
Matched Description: … Fluvoxamine has been in use in clinical practice since 1983 and has a clinical trial database comprised ... As of the end of 1995, more than 10 million patients worldwide have been treated with fluvoxamine. ... It was launched in the US in December 1994 and in Japan in June 1999. …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Matched Products: … VERLIN TABLETAS X 50 MG …

Ceftriaxone

Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic. It has a very long half-life compared to other cephalosporins and is high penetrable into the meninges , eyes , and inner ear . Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins, but worse activity against methicillin-susceptible S.aureus. Ceftriaxone...
Approved
Matched Description: … [A215582] It has a very long half-life compared to other cephalosporins and is high penetrable into the ... meninges[A215582], eyes[A215647], and inner ear[A215627]. ... Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins …
Matched Mixtures name: … Hovid Ceftriaxone 1g with Lidocaine 1% ... Hovid-Ceftriaxone 0.5g with Lidocaine 1% …
Matched Products: … Ceftriaxone and Dextrose …

Dequalinium

Dequalinium is an antibacterial agent with multi-targeted actions. It also possesses antifungal, antiparasitic, antiviral, anticancer, and neuroprotective properties. It is a quaternary ammonium compound, as it consists of an amphipathic cation with two aminoquinaldinium rings at both ends of a long hydrophobic hydrocarbon chain. Due to its flexible structure, dequalinium...
Approved
Investigational
Matched Description: … It also possesses antifungal, antiparasitic, antiviral, anticancer, and neuroprotective properties. ... various OTC products to treat conditions of oral infections and inflammation. ... Due to its flexible structure, dequalinium was investigated to build drug and gene delivery systems. …
Matched Categories: … Antiseptics and Disinfectants ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … CORYFIN GOLA …

Asunercept

Asunercept is under investigation in clinical trial NCT02853565 (A Study of CAN008 for Newly Diagnosed Glioblastoma Multiforme).
Investigational
Matched Synonyms: … FAS ANTIGEN (HUMAN EXTRACELLULAR DOMAIN FRAGMENT) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (HUMAN FC FRAGMENT …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Ontorpacept

Investigational
Matched Synonyms: … (human) fusion protein with immunoglobulin g1 (human fc fragment), dimer …

Vibrio cholerae Ogawa 50 classical biotype, heat inactivated

Approved
Matched Name: … Vibrio cholerae Ogawa 50 classical biotype, heat inactivated …
Matched Mixtures name: … DUKORAL VACCINE AGAINST CHOLERA AND ETEC-DIARRHOEA …

Cosfroviximab

Investigational
Matched Synonyms: … chain), disulfide with human-mus musculus monoclonal c13c6-fr1 .kappa. ... ebolavirus/sudan ebolavirus/tai forest ebolavirus glycoprotein) (human-mus musculus monoclonal c13c6-fr1 heavy …

Edobacomab

Investigational
Matched Synonyms: … -chain), disulfide with mouse monoclonal xmmen-0e5 light chain, pentameric dimer ... Immunoglobulin m (mouse monoclonal xmmen-0e5 anti-endotoxin), disulfide with mouse monoclonal xmmen-0e5 ... Immunoglobulin m (mouse monoclonal xmmen-oe5 anti-endotoxin), disulfide with mouse monoclonal xmmen-oe5 …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Levocarnitine

Constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.
Approved
Investigational
Matched Description: … Constituent of striated muscle and liver. ... It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids and Derivatives …
Matched Products: … STEP …

Hyoscyamine

Hyoscyamine is a tropane alkaloid and the levo-isomer of atropine. It is commonly extracted from plants in the Solanaceae or nightshade family. Research into the action of hyoscyamine in published literature dates back to 1826. Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic...
Approved
Matched Synonyms: … Hyoscyamin …
Matched Description: … Hyoscyamine is a tropane alkaloid and the levo-isomer of [atropine]. ... [A228713] Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic …
Matched Mixtures name: … Phenazopyridine Hydrochloride, Hyoscyamine Hydrobromide, and Butabarbital ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide …
Matched Categories: … Alimentary Tract and Metabolism ... Belladonna and Derivatives, Plain ... hyoscyamine and psycholeptics …

BS-001

BS-001 is a recombinant oncolytic herpes simplex virus type II (OH2) therapeutic injection (Vero cell) for human use (rHSV2hGM-CSF).
Investigational
Matched Synonyms: … Recombinant Oncolytic Herpes Simplex Virus Type II (OH2) Therapeutic Injection (Vero Cell) for Human …
Matched Description: … BS-001 is a recombinant oncolytic herpes simplex virus type II (OH2) therapeutic injection (Vero cell …
Displaying drugs 626 - 650 of 848 in total