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Displaying drugs 626 - 650 of 849 in total

Mecbotamab vedotin

Mecbotamab vedotin is an anti-Axl humanized monoclonal antibody conjugated to monomethyl auristatin E using a cleavable linker (CAB-Axl-ADC).
Investigational
Matched Synonyms: … -CHAIN, DIMER, THIOETHER WITH N-(((4-((N-(6-(3-MERCAPTO-2,5-DIOXO ... HUMAN TYROSINE KINASE RECEPTOR AXL) (HUMAN-MUS MUSCULUS MONOCLONAL BA301 .GAMMA.1-CHAIN), DISULFIDE WITH …

Didecyldimethylammonium

Approved
Experimental
Matched Mixtures name: … SANIVIR Hands, Body, and Surfaces Sanitizer ... KLEANMANN - Hand Sanitizer and Surface Disinfectant …
Matched Categories: … Antiseptics and Disinfectants …
Matched Products: … Steri Hand sanitizer without washing …

P-BCMA-101

P-BCMA-101 is an autologous CAR-T therapy developed using Poseida’s piggyBac platform technology.
Investigational
Matched Synonyms: … Autologous T-cells transfected with PiggyBac transposon plasmid vector expressing B-cell maturation antigen …

Gresonitamab

Investigational
Matched Synonyms: … PEPTIDE LINKER (GGGGS) FUSION PROTEIN WITH IMMUNOGLOBULIN ANTI-(HUMAN CD3 ANTIGEN .EPSILON. ... 18.2) (HUMAN MONOCLONAL HWZV_KLA_L SINGLE-CHAIN VARIABLE FRAGMENT VH1-(GGGGS)3-VL1) FUSION PROTEIN WITH …

Vepsitamab

Investigational
Matched Synonyms: … PEPTIDE LINKER (GGGGS) FUSION PROTEIN WITH IMMUNOGLOBULIN ANTI-(HUMAN CD3 ANTIGEN .EPSILON. ... 17) (HUMAN MONOCLONAL MUC17_CD3_ALT2 SINGLE-CHAIN VARIABLE FRAGMENT VH1-(GGGGS)3-VL1) FUSION PROTEIN WITH …

Povidone

Povidone, also known as polyvinylpyrrolidone (PVP) or polyvidone, is a synthetic water-soluble polymer made from the monomer N-vinylpyrrolidone used as a binder in many pharmaceutical tablets and lubricant in eye drops. It is also used in many technical applications with various roles as an adhesive, additive, and emulsifier. When in...
Approved
Withdrawn
Matched Description: … It is also used in many technical applications with various roles as an adhesive, additive, and emulsifier ... component, mainly contributes to this effect, and povidone acts as a carrier [A32988]. ... water-soluble polymer made from the monomer N-vinylpyrrolidone used as a binder in many pharmaceutical tablets and …
Matched Mixtures name: … Rohto Sun and Sport ... Redness reliever and Lubricant ... Meijer Advanced Redness and Irritation Relief …
Matched Products: … iVizia Lubricant Eye for Severe Night Dry Eyes …

Asunercept

Asunercept is under investigation in clinical trial NCT02853565 (A Study of CAN008 for Newly Diagnosed Glioblastoma Multiforme).
Investigational
Matched Synonyms: … FAS ANTIGEN (HUMAN EXTRACELLULAR DOMAIN FRAGMENT) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (HUMAN FC FRAGMENT …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Ontorpacept

Investigational
Matched Synonyms: … (human) fusion protein with immunoglobulin g1 (human fc fragment), dimer …

Cosfroviximab

Investigational
Matched Synonyms: … chain), disulfide with human-mus musculus monoclonal c13c6-fr1 .kappa. ... ebolavirus/sudan ebolavirus/tai forest ebolavirus glycoprotein) (human-mus musculus monoclonal c13c6-fr1 heavy …

Levocarnitine

Constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.
Approved
Investigational
Matched Description: … Constituent of striated muscle and liver. ... It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids and Derivatives …
Matched Products: … STEP …

Hepatitis B Vaccine (Recombinant)

Hepatitis B Vaccine is an ingredient in the EMA-withdrawn product Quintanrix. It is marketed in Canada as Engerix B. It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada. The hepatitis B virus induces a severe form of viral hepatitis. Other causative agents are hepatitis...
Approved
Withdrawn
Matched Description: … lifetime (mostly young adults); between 5% and 10% of infections lead to persistent viremia (carrier ... Carriers are at a high risk of developing chronic liver disease which may lead to cirrhosis or primary ... Transmission of the virus occurs through percutaneous contact with contaminated blood, serum or plasma …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Bacterial and viral vaccines, combined ... haemophilus influenzae B and hepatitis B …
Matched Products: … Recombivax HB (with Preservative) ... Recombivax HB (adult Dialysis With Preservative) …

Cyclobenzaprine

Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961 and has been available for human use since 1977. It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from Amitriptyline by only a single double bond.[A185039,A184982] Since its approval, it has...
Approved
Matched Description: … Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961[A185039] and has been …
Matched Products: … Comfort Pac With Cyclobenzaprine …

Sotatercept

Sotatercept is an activin signalling inhibitor. It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. On March 26, 2024, sotatercept was approved by the FDA for the treatment of pulmonary arterial hypertension...
Approved
Investigational
Matched Synonyms: … ACTIVIN RECEPTOR TYPE IIA (SYNTHETIC HUMAN EXTRACELLULAR DOMAIN-CONTAINING FRAGMENT) FUSION PROTEIN WITH ... IMMUNOGLOBULIN G1 (SYNTHETIC HUMAN HEAVY CHAIN FC FRAGMENT), DIMER ... HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN HEAVY …
Matched Description: … [L50361] Sotatercept works to resolve the imbalance in activin–growth differentiation factor and BMP …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Nacystelyn

Investigational
Matched Synonyms: … L-lysine, compd. with n-acetyl-l-cysteine …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Porgaviximab

Investigational
Matched Synonyms: … with human-mus musculus monoclonal c2g4 .kappa. ... KAPPA, ANTI-(EBOLAVIRUS GLYCOPROTEIN) CHIMERIC HOMO SAPIENS-MUS MUSCULUS MONOCLONAL ANTIBODY: .GAMMA.1 HEAVY ... Immunoglobulin g1, anti-(ebolavirus glycoprotein) (human-mus musculus monoclonal c2g4 heavy chain), disulfide …

Timolumab

Timolumab is a recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion protein-1 (VAP-1).
Investigational
Matched Synonyms: … recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion …
Matched Description: … Timolumab is a recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Fluvoxamine

Fluvoxamine is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor. Though it is in the same class as other SSRI drugs, it is most often used to treat obsessive-compulsive disorder. Fluvoxamine has been in use in clinical practice since 1983 and has a clinical trial database comprised...
Approved
Investigational
Matched Description: … Fluvoxamine has been in use in clinical practice since 1983 and has a clinical trial database comprised ... As of the end of 1995, more than 10 million patients worldwide have been treated with fluvoxamine. ... It was launched in the US in December 1994 and in Japan in June 1999. …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Matched Products: … VERLIN TABLETAS X 50 MG …

Denecimig

Delpacibart is a humanized, bispecific, bivalent monoclonal antibody against coagulation factor 9.
Investigational
Matched Synonyms: … -lysine], anti-(human blood-coagulation factor IX) (human clone 0365-0001-9985 γ4-chain), disulfide with ... human clone 0365-0001-9985 κ-chain, (228.fwdarw.226′),(231.fwdarw.229′)-bis(disulfide) with anti-(human …

Flavin adenine dinucleotide

A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972) Flavin adenine dinucleotide is approved for use in Japan under the trade name Adeflavin as an ophthalmic treatment for vitamin B2 deficiency.
Approved
Matched Synonyms: … Adenosine 5'-(trihydrogen pyrophosphate), 5'-5'-ester with riboflavine ... Riboflavin 5'-(trihydrogen diphosphate), 5'-5'-ester with adenosine …
Matched Description: … A condensation product of riboflavin and adenosine diphosphate. ... ., D-amino acid oxidase and L-amino acid oxidase. …
Matched Categories: … Enzymes and Coenzymes ... Nucleic Acids, Nucleotides, and Nucleosides …

Vibrio cholerae Inaba 48 classical biotype, heat inactivated

Approved
Matched Name: … Vibrio cholerae Inaba 48 classical biotype, heat inactivated …
Matched Mixtures name: … DUKORAL VACCINE AGAINST CHOLERA AND ETEC-DIARRHOEA …

Retlirafusp alfa

Investigational
Matched Synonyms: … (human isoform 1), disulfide with (85-glutamic acid) human-mus musculus monoclonal SHR-1316 .kappa. ... peptide linker ((ggggs)4g) fusion protein with 20-136-type II transforming growth factor .beta. receptor ... human programmed death-ligand 1) (human-mus musculus monoclonal SHR-1316 .gamma.4-chain) fusion protein with …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Nicardipine

A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents. [PubChem]
Approved
Investigational
Matched Description: … It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents ... It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without ... A potent calcium channel blockader with marked vasodilator action. …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Selective Calcium Channel Blockers With Mainly Vascular Effects …
Matched Products: … VERDIF …

Atracurium besylate

A non-depolarizing neuromuscular blocking agent with short duration of action. Its lack of significant cardiovascular effects and its lack of dependence on good kidney function for elimination provide clinical advantage over alternate non-depolarizing neuromuscular blocking agents.
Approved
Matched Description: … Its lack of significant cardiovascular effects and its lack of dependence on good kidney function for ... A non-depolarizing neuromuscular blocking agent with short duration of action. …
Matched Products: … Atracurium - (for Multiple Dose Vial - With Preservative) …

Neomycin

Neomycin is a broad-spectrum aminoglycoside antibiotic drug that is derived from the metabolic products of Streptomyces fradiae. Neomycin is a complex comprised of three components, neomycin A, B, and C. Neomycin B, also known as framycetin, is the most active component of the complex and neomycin C is the isomer...
Approved
Vet approved
Matched Description: … [L11979] It is also used in combination with [polymyxin B] sulfates and [hydrocortisone] in otic suspensions ... [L10532] Neomycin is also used in combination with [polymyxin B] sulfates and [dexamethasone] in ophthalmic ... [A175042] Neomycin is active against both gram-positive and gram-negative organisms and mediates its …
Matched Mixtures name: … CVS Health Triple Antibiotic with Pain Relief ... health and .beyond Triple Antibiotic ... CVS Health Medication and Topical Refill Pouch …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Antiinfectives and Antiseptics for Local Oral Treatment …
Matched Products: … Single Antibiotic with Neomycin …

Hexylresorcinol

Hexylresorcinol is a substituted dihydroxybenzene. It exhibits antiseptic, anthelmintic, and local anesthetic properties. It can be found in topical applications for minor skin infections and in oral solutions or throat lozenges for pain relief and first aid antiseptic. The compound may also be used commonly in various commercial cosmetic anti-aging...
Approved
Matched Description: … for pain relief and first aid antiseptic. ... It exhibits antiseptic, anthelmintic, and local anesthetic properties. ... It can be found in topical applications for minor skin infections and in oral solutions or throat lozenges …
Matched Products: … Antiseptic Throat Lozenges (with Hexylresorcinol) …
Displaying drugs 626 - 650 of 849 in total