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Displaying drugs 626 - 650 of 5178 in total
Influenza A virus A/Cambodia/e0826360/2020 IVR-224 (H3N2) antigen (propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Cambodia/e0826360/2020 IVR-224 (H3N2) antigen (propiolactone inactivated) …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …
Matched Categories: … Inactivated Influenza A Virus Vaccine …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …
Matched Categories: … Inactivated Influenza A Virus Vaccine …
Influenza A virus A/Cambodia/e0826360/2020 IVR-224 (H3N2) antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Cambodia/e0826360/2020 IVR-224 (H3N2) antigen (formaldehyde inactivated) …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …
Matched Categories: … Inactivated Influenza A Virus Vaccine …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …
Matched Categories: … Inactivated Influenza A Virus Vaccine …
Efinaconazole
Efinaconazole is a 14 alpha-demethylase inhibitor indicated in the treatment of fungal infection of the nail, known as onychomycosis. It was approved for use in Canada and the USA in 2014 and is marketed by Valeant Pharmaceuticals North America LLC under the name Jublia.
Approved
Matched Synonyms: … (2R,3R)-2-(2,4-Difluorophenyl)-3-(4-methylene-1-piperidinyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol …
Matched Iupac: … (2R,3R)-2-(2,4-difluorophenyl)-3-(4-methylidenepiperidin-1-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol …
Matched Description: … It was approved for use in Canada and the USA in 2014 and is marketed by Valeant Pharmaceuticals North ... Efinaconazole is a 14 alpha-demethylase inhibitor indicated in the treatment of fungal infection of the …
Matched Categories: … Imidazole and Triazole Derivatives …
Matched Iupac: … (2R,3R)-2-(2,4-difluorophenyl)-3-(4-methylidenepiperidin-1-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol …
Matched Description: … It was approved for use in Canada and the USA in 2014 and is marketed by Valeant Pharmaceuticals North ... Efinaconazole is a 14 alpha-demethylase inhibitor indicated in the treatment of fungal infection of the …
Matched Categories: … Imidazole and Triazole Derivatives …
Cobicistat
Cobicistat, marketed under the name Tybost (formerly GS-9350), indicated for treating infection with human immunodeficiency virus (HIV). Although it does not have any anti-HIV activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and therefore increases the systemic exposure of coadministered agents that are metabolized...
Approved
Matched Synonyms: … 1,3-thiazol-5-ylmethyl [(2R,5R)-5-{[(2S)-2-({[(2-isopropyl-1,3-thiazol-4-yl)methyl](methyl)carbamoyl} ... amino)-4-(morpholin-4-yl)butanoyl]amino}-1,6-diphenylhexan-2-yl]carbamate …
Matched Iupac: … (1,3-thiazol-5-yl)methyl N-[(2R,5R)-5-[(2S)-2-{[methyl({[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl})carbamoyl ... ]amino}-4-(morpholin-4-yl)butanamido]-1,6-diphenylhexan-2-yl]carbamate …
Matched Description: … a decreased side effect profile. ... cytochrome P450 3A isoforms (CYP3A) and therefore increases the systemic exposure of coadministered ... Although it does not have any anti-HIV activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting …
Matched Categories: … darunavir and cobicistat ... atazanavir and cobicistat ... Metabolic Side Effects of Drugs and Substances ... emtricitabine, tenofovir alafenamide, darunavir and cobicistat ... emtricitabine, tenofovir disoproxil, elvitegravir and cobicistat …
Matched Iupac: … (1,3-thiazol-5-yl)methyl N-[(2R,5R)-5-[(2S)-2-{[methyl({[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl})carbamoyl ... ]amino}-4-(morpholin-4-yl)butanamido]-1,6-diphenylhexan-2-yl]carbamate …
Matched Description: … a decreased side effect profile. ... cytochrome P450 3A isoforms (CYP3A) and therefore increases the systemic exposure of coadministered ... Although it does not have any anti-HIV activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting …
Matched Categories: … darunavir and cobicistat ... atazanavir and cobicistat ... Metabolic Side Effects of Drugs and Substances ... emtricitabine, tenofovir alafenamide, darunavir and cobicistat ... emtricitabine, tenofovir disoproxil, elvitegravir and cobicistat …
Prednisone acetate
Approved
Experimental
Investigational
Matched Iupac: … ,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate ... 2-[(1R,3aS,3bS,9aR,9bS,11aS)-1-hydroxy-9a,11a-dimethyl-7,10-dioxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Omacetaxine mepesuccinate
Omacetaxine mepesuccinate (formerly known as HHT or Homoharringtonine), is a cephalotaxine ester and protein synthesis inhibitor with established clinical activity as a single agent in hematological malignancies. Omacetaxine mepesuccinate is synthesized from cephalotaxine, which is an extract from the leaves of the plant, Cephalotaxus species. In October 2005, omacetaxine mepesuccinate...
Approved
Investigational
Matched Synonyms: … 3]benzazepin-1-yl] 4-methyl (2R)-2-hydroxy-2-(4-hydroxy-4-methylpentyl)butanedioate ... 1-[(1S,3aR,14bS)-2-Methoxy-1,5,6,8,9,14b-hexahydro-4H-cyclopenta[a][1,3]dioxolo[4,5-H]pyrrolo[2,1-b][ ... CEPHALOTAXINE 4-METHYL (2R)-2-HYDROXY-2-(4-HYDROXY-4-METHYLPENTYL)BUTANEDIOATE (ESTER) …
Matched Iupac: … yl 1-methyl (3R)-3-hydroxy-3-(4-hydroxy-4-methylpentyl)butanedioate ... methoxy-16,18-dioxa-10-azapentacyclo[11.7.0.0^{2,6}.0^{6,10}.0^{15,19}]icosa-1(20),4,13,15(19)-tetraen-3- …
Matched Description: … FDA approved for patients who are intolerant and/or resistant to two or more tyrosine kinase inhibitors ... Omacetaxine mepesuccinate (formerly known as HHT or Homoharringtonine), is a cephalotaxine ester and ... protein synthesis inhibitor with established clinical activity as a single agent in hematological malignancies …
Matched Salts cas: … 457895-79-3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antineoplastic and Immunomodulating Agents …
Matched Iupac: … yl 1-methyl (3R)-3-hydroxy-3-(4-hydroxy-4-methylpentyl)butanedioate ... methoxy-16,18-dioxa-10-azapentacyclo[11.7.0.0^{2,6}.0^{6,10}.0^{15,19}]icosa-1(20),4,13,15(19)-tetraen-3- …
Matched Description: … FDA approved for patients who are intolerant and/or resistant to two or more tyrosine kinase inhibitors ... Omacetaxine mepesuccinate (formerly known as HHT or Homoharringtonine), is a cephalotaxine ester and ... protein synthesis inhibitor with established clinical activity as a single agent in hematological malignancies …
Matched Salts cas: … 457895-79-3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antineoplastic and Immunomodulating Agents …
Cyclothiazide
As a diuretic, cyclothiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. Thiazides like cyclothiazide also inhibit sodium ion transport across the renal tubular epithelium through binding to the thiazide sensitive sodium-chloride transporter....
Approved
Matched Synonyms: … 6-chloro-3-(2-norbornen-5-yl)-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide ... 6-chloro-3,4-dihydro-3-(2-norbornen-5-yl)-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide ... 6-chloro-3,4-dihydro-3-(2-norbornen-5-yl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide …
Matched Iupac: … 3-{bicyclo[2.2.1]hept-5-en-2-yl}-6-chloro-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Matched Description: … As a diuretic, cyclothiazide inhibits active chloride reabsorption at the early distal tubule via the ... corticosteroid and estrogen therapy. ... Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... cyclothiazide and potassium ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Iupac: … 3-{bicyclo[2.2.1]hept-5-en-2-yl}-6-chloro-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Matched Description: … As a diuretic, cyclothiazide inhibits active chloride reabsorption at the early distal tubule via the ... corticosteroid and estrogen therapy. ... Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... cyclothiazide and potassium ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Proparacaine
Proparacaine is a topical anesthetic drug of the amino ester group. It is found in ophthalmic solutions at a concentration of 0.5% as the hydrochloride salt.
Approved
Vet approved
Matched Iupac: … 2-(diethylamino)ethyl 3-amino-4-propoxybenzoate …
Matched Description: … Proparacaine is a topical anesthetic drug of the amino ester group. ... It is found in ophthalmic solutions at a concentration of 0.5% as the hydrochloride salt. …
Matched Mixtures name: … Fluorescein Sodium and Proparacaine Hydrochloride …
Matched Description: … Proparacaine is a topical anesthetic drug of the amino ester group. ... It is found in ophthalmic solutions at a concentration of 0.5% as the hydrochloride salt. …
Matched Mixtures name: … Fluorescein Sodium and Proparacaine Hydrochloride …
Bithionol
Bithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders. Approvals of the NDA's for bithionol drug products were withdrawn on October 24, 1967 (see the Federal Register of October 31, 1967 (32...
Approved
Withdrawn
Matched Synonyms: … 2-Hydroxy-3,5-dichlorophenyl sulfide ... 2-Hydroxy-3,5-dichlorophenyl sulphide ... Bis(3,5-dichloro-2-hydroxyphenyl) sulfide …
Matched Iupac: … 2,4-dichloro-6-[(3,5-dichloro-2-hydroxyphenyl)sulfanyl]phenol …
Matched Description: … Bithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Matched Iupac: … 2,4-dichloro-6-[(3,5-dichloro-2-hydroxyphenyl)sulfanyl]phenol …
Matched Description: … Bithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Tedizolid phosphate
Drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and penicillin-resistant Streptococcus penumoniae, represent a massive public health threat.[A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the previously approved linezolid and is generally effective against multidrug-resistant Gram-positive bacteria. Tedizolid is indicated for the...
Approved
Matched Synonyms: … [(5R)-3-{3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin-5-yl]methyl …
Matched Iupac: … {[(5R)-3-{3-fluoro-4-[6-(2-methyl-2H-1,2,3,4-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin- …
Matched Description: … previously approved [linezolid] and is generally effective against multidrug-resistant Gram-positive ... This product is currently available as both an oral tablet and as a powder for intravenous injection. ... [L11232, A199086, A199050] Tedizolid was approved by the FDA on June 20, 2014, for sale by Cubist …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Iupac: … {[(5R)-3-{3-fluoro-4-[6-(2-methyl-2H-1,2,3,4-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin- …
Matched Description: … previously approved [linezolid] and is generally effective against multidrug-resistant Gram-positive ... This product is currently available as both an oral tablet and as a powder for intravenous injection. ... [L11232, A199086, A199050] Tedizolid was approved by the FDA on June 20, 2014, for sale by Cubist …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Influenza A virus A/Singapore/INFIMH-16-0019/2016 NIB-104 (H3N2) antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Singapore/INFIMH-16-0019/2016 NIB-104 (H3N2) antigen (formaldehyde inactivated) …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …
Influenza A virus A/Indiana/08/2018 (H3N2) antigen (MDCK cell derived, propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Indiana/08/2018 (H3N2) antigen (MDCK cell derived, propiolactone inactivated) …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …
Influenza A virus A/Darwin/11/2021 (H3N2) antigen (MDCK cell derived, propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Name: … Influenza A virus A/Darwin/11/2021 (H3N2) antigen (MDCK cell derived, propiolactone inactivated) …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection …
Matched Categories: … Inactivated Influenza A Virus Vaccine …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection …
Matched Categories: … Inactivated Influenza A Virus Vaccine …
Rizatriptan
Rizatriptan is a second-generation triptan and a selective 5-HT1B and 5-HT1D receptor agonist. Used in the treatment of migraines, rizatriptan was first approved in the US in 1998. Rizatriptan is available in oral tablets, orally disintegrating tablets (wafers), and oral film formulations.
Approved
Matched Synonyms: … N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]-ethanamine ... N,N-Dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-3-ethanamine …
Matched Iupac: … dimethyl(2-{5-[(1H-1,2,4-triazol-1-yl)methyl]-1H-indol-3-yl}ethyl)amine …
Matched Description: … Rizatriptan is a second-generation triptan [A258918] and a selective 5-HT1B and 5-HT1D receptor ... [L46018] Used in the treatment of migraines, rizatriptan was first approved in the US in 1998. ... [L46018] Rizatriptan is available in oral tablets, orally disintegrating tablets (wafers), and oral film …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Monoamine Oxidase A Substrates ... Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Products: … MİGREOUT 5 MG EFERVESAN TABLET, 3 ADET ... MİGREOUT 10 MG EFERVESAN TABLET, 3 ADET ... MAXALT 10 MG RAPIDISC TABLET, 3 ADET …
Matched Iupac: … dimethyl(2-{5-[(1H-1,2,4-triazol-1-yl)methyl]-1H-indol-3-yl}ethyl)amine …
Matched Description: … Rizatriptan is a second-generation triptan [A258918] and a selective 5-HT1B and 5-HT1D receptor ... [L46018] Used in the treatment of migraines, rizatriptan was first approved in the US in 1998. ... [L46018] Rizatriptan is available in oral tablets, orally disintegrating tablets (wafers), and oral film …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Monoamine Oxidase A Substrates ... Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Products: … MİGREOUT 5 MG EFERVESAN TABLET, 3 ADET ... MİGREOUT 10 MG EFERVESAN TABLET, 3 ADET ... MAXALT 10 MG RAPIDISC TABLET, 3 ADET …
2-mercaptobenzothiazole
Approved
Experimental
Vet approved
Matched Synonyms: … 2-MBT ... 2-Benzothiazolethiol ... Benzothiazole-2-thiol …
Matched Name: … 2-mercaptobenzothiazole …
Matched Iupac: … 2,3-dihydro-1,3-benzothiazole-2-thione …
Matched Salts name: … Sodium 2-mercaptobenzothiazole …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Name: … 2-mercaptobenzothiazole …
Matched Iupac: … 2,3-dihydro-1,3-benzothiazole-2-thione …
Matched Salts name: … Sodium 2-mercaptobenzothiazole …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Glofitamab
Glofitamab is a full-length bispecific monoclonal antibody with affinity for both CD20 and CD3 surface antigens found on B- and T-cells, respectively. It has a 2:1 configuration, with bivalency towards CD20 and monovalency towards CD3, and works by recruiting T-cells directly to the surface of cancerous B-cells.[L45698,A258488]
Glofitamab was approved...
Approved
Investigational
Matched Description: … It has a 2:1 configuration, with bivalency towards CD20 and monovalency towards CD3, and works by recruiting ... Glofitamab is a full-length bispecific monoclonal antibody with affinity for both CD20 and CD3 surface ... [L45698,A258488]
Glofitamab was approved by Health Canada in March 2023 for the treatment of certain …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Momelotinib
Momelotinib is a Janus Kinase 1 (JAK1) and 2 (JAK2) inhibitor. It is a competitive inhibitor of JAK ATP binding. First approved by the FDA on September 15, 2023, momelotinib is used to treat myelofibrosis. Myelofibrosis (MF) is a group of myeloproliferative neoplasms characterized by abnormal proliferative hematopoietic stem cells,...
Approved
Investigational
Matched Synonyms: … N-(CYANOMETHYL)-4-(2-(4-MORPHOLINOANILINO)PYRIMIDIN-4-YL)BENZAMIDE …
Matched Iupac: … N-(cyanomethyl)-4-(2-{[4-(morpholin-4-yl)phenyl]amino}pyrimidin-4-yl)benzamide …
Matched Description: … Momelotinib is a Janus Kinase 1 (JAK1) and 2 (JAK2) inhibitor. ... [A261566] First approved by the FDA on September 15, 2023,[L48206] momelotinib is used to treat myelofibrosis ... It is a competitive inhibitor of JAK ATP binding. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … N-(cyanomethyl)-4-(2-{[4-(morpholin-4-yl)phenyl]amino}pyrimidin-4-yl)benzamide …
Matched Description: … Momelotinib is a Janus Kinase 1 (JAK1) and 2 (JAK2) inhibitor. ... [A261566] First approved by the FDA on September 15, 2023,[L48206] momelotinib is used to treat myelofibrosis ... It is a competitive inhibitor of JAK ATP binding. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
CL-315555
CL-315555 is the C isomer of Verteporfin.
Approved
Matched Iupac: … 3-[(23S,24R)-14-ethenyl-5-(3-methoxy-3-oxopropyl)-22,23-bis(methoxycarbonyl)-4,10,15,24-tetramethyl-25,26,27,28 …
Buprenorphine
Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist used for the treatment of severe pain.[A186283,A186292] It is also commonly used as an alternative to methadone for the treatment of severe opioid addiction. Buprenorphine is commercially available as the brand name product Suboxone which is...
Approved
Illicit
Investigational
Vet approved
Matched Synonyms: … 2-(N-cyclopropylmethyl-4,5α-epoxy-3-hydroxy-6-methoxy-6,14-endo-ethanomorphinan-6α-yl)-3,3-dimethyl-2 ... 2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(14R)-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12 ... ]icosa-7,9,11-trien-16-yl]-3,3-dimethyl-2-butanol …
Matched Iupac: … (1S,2R,6S,14R,15R,16R)-3-(cyclopropylmethyl)-16-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-15-methoxy-13 ... -oxa-3-azahexacyclo[13.2.2.1^{2,8}.0^{1,6}.0^{6,14}.0^{7,12}]icosa-7,9,11-trien-11-ol …
Matched Description: … Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist ... with a lower risk of overdose and respiratory depression. ... Buprenorphine has a number of unique pharmacokinetic and pharmacodynamic properties that make it a preferred …
Matched Mixtures name: … Suboxone 8 mg/2 mg sublingual tablets ... Suboxone 2 mg/0.5 mg sublingual tablets ... SUBOXONE 8 MG/2 MG DILALTI TABLET, 7 ADET …
Matched Products: … BUPENSAN 2 MG ... BUPRENORPHIN-NEURAX 2 MG ... SUBUTEX SUBLINGUAL TABLETS 2 mg …
Matched Iupac: … (1S,2R,6S,14R,15R,16R)-3-(cyclopropylmethyl)-16-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-15-methoxy-13 ... -oxa-3-azahexacyclo[13.2.2.1^{2,8}.0^{1,6}.0^{6,14}.0^{7,12}]icosa-7,9,11-trien-11-ol …
Matched Description: … Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist ... with a lower risk of overdose and respiratory depression. ... Buprenorphine has a number of unique pharmacokinetic and pharmacodynamic properties that make it a preferred …
Matched Mixtures name: … Suboxone 8 mg/2 mg sublingual tablets ... Suboxone 2 mg/0.5 mg sublingual tablets ... SUBOXONE 8 MG/2 MG DILALTI TABLET, 7 ADET …
Matched Products: … BUPENSAN 2 MG ... BUPRENORPHIN-NEURAX 2 MG ... SUBUTEX SUBLINGUAL TABLETS 2 mg …
Carindacillin
Carindacillin or Carbenicillin isdanyl was an oral penicillin prodrug of carbenicillin marketed by Pfizer as Geocillin. It is no longer marketed in the United States.
Approved
Investigational
Matched Synonyms: … 6β-{2-[(2,3-dihydro-1H-inden-5-yloxy)carbonyl]-2-phenylacetamido}-2,2-dimethylpenam-3α-carboxylic acid …
Matched Iupac: … (2S,5R,6R)-6-[3-(2,3-dihydro-1H-inden-5-yloxy)-3-oxo-2-phenylpropanamido]-3,3-dimethyl-7-oxo-4-thia-1 ... -azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … (2S,5R,6R)-6-[3-(2,3-dihydro-1H-inden-5-yloxy)-3-oxo-2-phenylpropanamido]-3,3-dimethyl-7-oxo-4-thia-1 ... -azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Vadadustat
One of the most common symptoms of advanced renal disease is anemia, caused primarily by the inability of the kidney to respond to anemic conditions with a corresponding increase in erythropoietin (EPO) production. The treatment of anemia associated with chronic kidney disease (CKD) has traditionally involved the administration of exogenous...
Approved
Investigational
Matched Synonyms: … N-(5-(3-Chlorophenyl)-3-hydroxypyridine-2-carbonyl)glycine ... Glycine, N-((5-(3-chlorophenyl)-3-hydroxy-2-pyridinyl)carbonyl)- …
Matched Iupac: … 2-{[5-(3-chlorophenyl)-3-hydroxypyridin-2-yl]formamido}acetic acid …
Matched Description: … [A244145,A244155] It was first approved in Japan in 2020,[L50371] and in April 2023, it was approved ... [A244165] A relatively new and alternative treatment option for patients with anemia associated with ... [A244165] Vadadustat is an orally administered inhibitor of HIF-PH with a safety and efficacy profile …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Iupac: … 2-{[5-(3-chlorophenyl)-3-hydroxypyridin-2-yl]formamido}acetic acid …
Matched Description: … [A244145,A244155] It was first approved in Japan in 2020,[L50371] and in April 2023, it was approved ... [A244165] A relatively new and alternative treatment option for patients with anemia associated with ... [A244165] Vadadustat is an orally administered inhibitor of HIF-PH with a safety and efficacy profile …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Empagliflozin
Empagliflozin is an inhibitor of sodium-glucose co-transporter-2 (SGLT2), the transporters primarily responsible for the reabsorption of glucose in the kidney. It is used clinically as an adjunct to diet and exercise, often in combination with other drug therapies,[L13673,L13679,L11479] for the management of type 2 diabetes mellitus. The first known inhibitor...
Approved
Matched Synonyms: … 1-chloro-4-(glucopyranos-1-yl)-2-(4-(tetrahydrofuran-3-yloxy)benzyl)benzene ... (1S)-1,5-anhydro-1-(4-chloro-3-{4-[(3S)-tetrahydrofuran-3-yloxy]benzyl}phenyl)-D-glucitol …
Matched Iupac: … (2S,3R,4R,5S,6R)-2-[4-chloro-3-({4-[(3S)-oxolan-3-yloxy]phenyl}methyl)phenyl]-6-(hydroxymethyl)oxane- …
Matched Description: … the first and only approved treatment in Europe and Canada for adults with symptomatic chronic heart ... Empagliflozin was further approved by the EMA in March 2022 and Health Canada in April 2022, making it ... therapies,[L13673,L13679,L11479] for the management of type 2 diabetes mellitus. …
Matched Categories: … Sodium-Glucose Transporter 2 Inhibitors ... Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors ... Alimentary Tract and Metabolism ... metformin and empagliflozin ... linagliptin and empagliflozin …
Matched Iupac: … (2S,3R,4R,5S,6R)-2-[4-chloro-3-({4-[(3S)-oxolan-3-yloxy]phenyl}methyl)phenyl]-6-(hydroxymethyl)oxane- …
Matched Description: … the first and only approved treatment in Europe and Canada for adults with symptomatic chronic heart ... Empagliflozin was further approved by the EMA in March 2022 and Health Canada in April 2022, making it ... therapies,[L13673,L13679,L11479] for the management of type 2 diabetes mellitus. …
Matched Categories: … Sodium-Glucose Transporter 2 Inhibitors ... Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors ... Alimentary Tract and Metabolism ... metformin and empagliflozin ... linagliptin and empagliflozin …
Bromhexine
Bromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased mucus secretion. It is derived from the Adhatoda vasica plant and aids in the clearance of excess mucus, improving breathing and reducing cough. It was introduced into the market in 1963, and is widely available as...
Approved
Matched Synonyms: … N-cyclohexyl-N-methyl-(2-amino-3,5-dibrombenzyl)amine ... 3,5-dibromo-N(alpha)-cyclohexyl-N(alpha)-methyltoluene-alpha-2-diamine …
Matched Description: … Bromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased ... and reducing cough. ... prevention and treatment of COVID-19 due to their interactions with cell receptors in the lungs. …
Matched Mixtures name: … BRONCODEX JARABE (GUAIFENESIN 2 G + BROMHEXINA HCI 0.08 G) …
Matched Categories: … Cough and Cold Preparations …
Matched Products: … DEXHEXINE 2% W/W WATER SOLUBLE POWDER …
Matched Description: … Bromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased ... and reducing cough. ... prevention and treatment of COVID-19 due to their interactions with cell receptors in the lungs. …
Matched Mixtures name: … BRONCODEX JARABE (GUAIFENESIN 2 G + BROMHEXINA HCI 0.08 G) …
Matched Categories: … Cough and Cold Preparations …
Matched Products: … DEXHEXINE 2% W/W WATER SOLUBLE POWDER …
Methohexital
An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia.
Approved
Matched Synonyms: … 5-Allyl-5-(3-hexyn-2-yl)-1-methylbarbituric acid ... (±)-5-allyl-1-methyl-5-(1-methyl-2-pentynyl)barbituric acid ... α-DL-1-methyl-5-allyl-5-(1'-methylpentyn-2-yl)barbituric acid …
Matched Iupac: … 5-(hex-3-yn-2-yl)-1-methyl-5-(prop-2-en-1-yl)-1,3-diazinane-2,4,6-trione …
Matched Description: … An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia …
Matched Categories: … Hypnotics and Sedatives …
Matched Iupac: … 5-(hex-3-yn-2-yl)-1-methyl-5-(prop-2-en-1-yl)-1,3-diazinane-2,4,6-trione …
Matched Description: … An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia …
Matched Categories: … Hypnotics and Sedatives …
Obeticholic acid
Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury often resulting in end-stage liver failure that requires liver transplantation. Obeticholic acid is a farnesoid-X receptor (FXR) agonist used to treat this condition, possibly allowing for increased survival. In 2016, it was granted approval...
Approved
Matched Iupac: … 3aS,3bS,4R,5R,5aS,7R,9aS,9bS,11aR)-5-ethyl-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a] …
Matched Description: … The NDA from Intercept Pharmaceuticals was approved in November 2019 and obeticholic acid is expected ... Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury ... advanced cirrhosis (e.g. those with portal hypertension or hepatic decompensation) due to a risk of …
Matched Categories: … Bile Acids and Salts ... Bile and Liver Therapy ... Bile acids and derivatives ... Alimentary Tract and Metabolism …
Matched Description: … The NDA from Intercept Pharmaceuticals was approved in November 2019 and obeticholic acid is expected ... Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury ... advanced cirrhosis (e.g. those with portal hypertension or hepatic decompensation) due to a risk of …
Matched Categories: … Bile Acids and Salts ... Bile and Liver Therapy ... Bile acids and derivatives ... Alimentary Tract and Metabolism …
Displaying drugs 626 - 650 of 5178 in total