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Displaying drugs 651 - 675 of 1113 in total

Methoxy polyethylene glycol-epoetin beta

Methoxy polyethylene glycol-epoetin beta is a chemically synthesised Erythropoiesis Stimulating Agent (ESA) with a longer half-life than erythropoietin. ESA is used to increase synthesis of red blood cells to treat chronic kidney disease associated anemia.
Approved
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Intercellular Signaling Peptides and Proteins …
Matched Products: … Mircera Solution for Injection 100mcg/0.3ml (Pre-filled Syringe) ... Mircera Solution for Injection 75mcg/0.3ml (Pre-filled Syringe) ... Mircera Solution for Injection 50mcg/0.3ml (Pre-filled Syringe) …

Bemiparin

Bemiparin is an antithrombotic and belongs to the group of drugs known as the low molecular weight heparins (LMWH). Like semuloparin, bemiparin is classified as an ultra-LMH because of its low mean molecular mass of 3600 daltons, which is a unique property of this class . These heparins have lower...
Approved
Investigational
Matched Description: … tumors and diabetic foot ulcers [L1468, A7866]. ... Bemiparin is an antithrombotic and belongs to the group of drugs known as the low molecular weight heparins ... These heparins have lower anti-thrombin activity than the traditional low molecular weight heparins and …
Matched Categories: … Heparin and similars ... Blood and Blood Forming Organs …
Matched Products: … HIBOR 2,500 IU ANTI XA/0.2ML SOLUTION FOR INJECTION IN PRE-FILLED SYRINGES ... HIBOR 10,000 IU ANTI XA/0.4 ML SOLUTION FOR INJECTION IN PRE-FILLED SYRINGES ... HIBOR 3,500 IU ANTI XA/0.2 ML SOLUTION FOR INJECTION IN PRE-FILLED SYRINGES …

Secukinumab

Secukinumab is a fully human monoclonal IgG1/κ antibody against interleukin-17A (IL-17A), a proinflammatory cytokine implicated in various chronic immune-mediated inflammatory disorders, such as plaque psoriasis. By blocking the actions of IL-17A, secukinumab works to inhibit the pro-inflammatory pathways that drive immune-mediated inflammatory disorders. Following its first global approval in Japan...
Approved
Matched Description: … in Japan in December 2014, secukinumab was approved by the European Commission on January 15, 2015, and ... chronic inflammatory conditions, such as plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … SCAPHO (POWDER FOR SOLUTION FOR INJECTION) ... Fraizeron 150mg Powder for Solution for Injection ... COSENTYX POWDER FOR SOLUTION FOR INJECTION 150MG/VIAL …

Bortezomib

Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma and mantle cell lymphoma. The 26S proteasome is a protein complex that degrades ubiquitinated proteins in the ubiquitin-proteasome pathway: reversible inhibition of the 26S proteasome, leading to cell cycle arrest and apoptosis of cancer cells,...
Approved
Investigational
Matched Description: … and mantle cell lymphoma. ... Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma ... ubiquitin-proteasome pathway: reversible inhibition of the 26S proteasome, leading to cell cycle arrest and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Retrox 3.5mg Powder for Solution for Injection ... MYBORTE POWDER FOR SOLUTION FOR INJECTION 3.5MG/VIAL ... BORTESUN POWDER FOR SOLUTION FOR INJECTION 3.5 mg …

Caspofungin

Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug class called the echinocandins, as coined by Merck & Co., Inc. It is typically administered intravenously. It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan of the fungal...
Approved
Matched Description: … It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan ... Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antimycotics for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … FUPASCIN POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 70MG/VIAL ... FUPASCIN POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 50MG/VIAL ... CASPODIN POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 50MG/VIAL …

Fondaparinux

Fondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and a O-methyl group at the reducing end of the molecule. It is structurally similar to polymeric glycosaminoglycan heparin and heparan sulfate (HS) when they are cleaved into monomeric units. The monomeric sequence in heparin and HS...
Approved
Investigational
Matched Description: … The monomeric sequence in heparin and HS is thought to form the high affinity binding site for the natural ... Fondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and ... It is structurally similar to polymeric glycosaminoglycan heparin and heparan sulfate (HS) when they …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … ARIXTRA 12.5MG/ML SOLUTION FOR INJECTION ... ARIXTRA 2.5MG/0.5ML SOLUTION FOR INJECTION ... Arixtra Solution for Injection 7.5 mg/0.6 ml …

Azithromycin

Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration . It was initially approved by the FDA in 1991 . It is primarily used for the treatment of respiratory, enteric and genitourinary infections and may be used instead of other macrolides for...
Approved
Matched Description: … It is primarily used for the treatment of respiratory, enteric and genitourinary infections and may be ... used instead of other macrolides for some sexually transmitted and enteric infections. ... Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue …
Matched Categories: … cefixime and azithromycin ... Macrolides, Lincosamides and Streptogramins ... azithromycin, fluconazole and secnidazole ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Zithrolide 500mg Powder for Solution for Infusion ... Azithromycin powder for solution for injection 500mg ... ZITHROMAX IV POWDER FOR SOLUTION FOR INFUSION 500 mg/vial …

Cyclophosphamide

Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active aldophosphamide. It has been used in the treatment of lymphoma and leukemia. Its side effect, alopecia, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects,...
Approved
Investigational
Matched Description: … It has been used in the treatment of lymphoma and leukemia. ... Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer. ... Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated …
Matched Mixtures name: … Procytox for Injection 2000mg Pws IV …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Cytoxan Pws for Inj 1000mg/vial ... Cytoxan Pws for Inj 2000mg/vial ... CYCRAM FOR INJECTION 1 g/vial …

Anifrolumab

Anifrolumab, or MEDI-546, is a type 1 interferon receptor (IFNAR) inhibiting IgG1κ monoclonal antibody indicated in the treatment of adults with moderate to severe systemic lupus erythematosus.[A237074,L34929] The standard therapy for systemic lupus erythematosus consists of antimalarials like hydroxychloroquine, glucocorticoids like dexamethasone, and disease modifying antirheumatic drugs like methotrexate.[A237079,L34929] Three...
Approved
Investigational
Matched Description: … [hydroxychloroquine], glucocorticoids like [dexamethasone], and disease modifying antirheumatic drugs ... [A237079,L34929] Three monoclonal antibodies (anifrolumab, [rontalizumab], and [sifalimumab]) that ... The design of early clinical trials of anti-interferon treatments such as anifrolumab, rontalizumab, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … SAPHNELO 300MG CONCENTRATE FOR SOLUTION FOR INFUSION …

Dexmedetomidine

An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
Approved
Vet approved
Matched Description: … An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and …
Matched Categories: … Hypnotics and Sedatives ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … ICUNES® 100mcg/ml Concentrate for Solution for Infusion ... PRECEDEX CONCENTRATE FOR SOLUTION FOR INFUSION 100 mcg/ml (Vial) ... Dexmedetomidine Hydrochloride for Injection …

Eptinezumab

Eptinezumab is a fully-humanized IgG1 antibody manufactured using yeast (Pichia pastoris) and developed by Lundbeck Seattle Biopharmaceuticals. Eptinezumab has been specifically designed to bind to both alpha and beta forms of the human calcitonin gene-related peptide (CGRP).[F94,A33105,A33106,A33108] It was approved by the FDA in February 2020 for the preventive treatment...
Approved
Investigational
Matched Description: … [L12318] Eptinezumab has been specifically designed to bind to both alpha and beta forms of the human ... Eptinezumab is a fully-humanized IgG1 antibody manufactured using yeast (_Pichia pastoris_) and developed ... [F94,A33105,A33106,A33108] It was approved by the FDA in February 2020 for the preventive treatment of …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … VYEPTI CONCENTRATE FOR SOLUTION FOR INFUSION 100MG/ML …

Amivantamab

Amivantamab, also known as JNJ-61186372, is an anti-EGFR-MET bispecific antibody, derived from Chinese hamster ovary cells, approved for the treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 20 insertion mutations, as detected by an FDA-approved test, whose...
Approved
Investigational
Matched Description: … [A235103,L34193] Patients with NSCLC often develop resistance to drugs that target EGFR and MET individually ... FDA approval on 21 May 2021,[L34193] followed by the approval by the EMA on 9 December 2021 [L41474] and ... Patients with NSCLC with exon 20 insertion mutations in EGFR do not respond to tyrosine kinase inhibitors, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … RYBREVANT 350mg/7mL Concentrate for Solution for Infusion …

Necitumumab

Necitumumab is an intravenously administered recombinant monoclonal IgG1 antibody used in the treatment of non-small cell lung cancer (NSCLC) as an EGFR antagonist. It functions by binding to epidermal growth factor receptor (EGFR) and prevents binding of its ligands, a process that is involved in cell proliferation, metastasis, angiogenesis, and...
Approved
Investigational
Matched Description: … Necitumumab is approved for use in combination with cisplatin and gemcitabine as a first-line treatment ... for metastatic squamous non-small cell lung cancer (NSCLC). ... It functions by binding to epidermal growth factor receptor (EGFR) and prevents binding of its ligands …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … PORTRAZZA CONCENTRATE FOR SOLUTION FOR INFUSION 800MG/50ML …

Tetrakis(2-methoxyisobutylisocyanide)copper(I) tetrafluoroborate

Tetrakis (2-methoxyisobutylisocyanide) copper (I) tetrafluoroborate is a component of Cardiolite, a technetium Tc99m-based imaging agent used for assessing myocardial perfusion.
Approved
Matched Description: … copper (I) tetrafluoroborate is a component of Cardiolite, a technetium Tc99m-based imaging agent used for …
Matched Products: … Kit for the Preparation of Technetium Tc99m Sestamibi ... Stamicis Kit for Radiopharmaceutical Preparation 1mg ... STAMICIS 1 mg Kit for Radiopharmaceutical Preparation …

Benzylpenicillin

Benzylpenicillin (Penicillin G) is narrow spectrum antibiotic used to treat infections caused by susceptible bacteria. It is a natural penicillin antibiotic that is administered intravenously or intramuscularly due to poor oral absorption. Penicillin G may also be used in some cases as prophylaxis against susceptible organisms. Natural penicillins are considered...
Approved
Vet approved
Matched Description: … *, and *Enterococcus faecalis*. ... Resistance patterns, susceptibility and treatment guidelines vary across regions. ... group D streptococci, viridans group streptococci, and non-penicillinase producing staphylococcus. …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Penicillin G Sodium for Injection ... Penicillin G Sodium for Injection, USP ... Penicillin G K for Inj,usp 5000000u/vial …

Busulfan

Busulfan is a bifunctional alkylating agent, having a selective immunosuppressive effect on bone marrow. It is not a structural analog of the nitrogen mustards. It has been used in the palliative treatment of chronic myeloid leukemia (myeloid leukemia, chronic), but although symptomatic relief is provided, no permanent remission is brought...
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Busulfan Kabi Injection 6mg/ml Concentrate for Solution for Infusion ... Busulfan for Injection ... CANBUSUL- Busulfan Injection 6 mg/ml Concentrate for Solution for Infusion …

Agalsidase alfa

Agalsidase alfa is a recombinant human α-galactosidase A similar to agalsidase beta. While patients generally do not experience a clinically significant difference in outcomes between the two drugs, some patients may experience greater benefit with agalsidase beta.[A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa,...
Approved
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Products: … REPLAGAL CONCENTRATE FOR SOLUTION FOR INFUSION 1 MG/ML …

Fulvestrant

Fulvestrant is a drug treatment of hormone receptor (HR)-positive metastatic breast cancer in post-menopausal women with disease progression following anti-estrogen therapy. It is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor. While it is used as monotherapy for the...
Approved
Investigational
Matched Description: … It is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and ... While it is used as monotherapy for the treatment of breast cancers, it is also used in combination with ... [alpelisib] for the treatment of HR-positive, human epidermal growth factor receptor 2 (HER2)-negative …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … FASLODEX SOLUTION FOR INJECTION 250MG/5 ML ... FEMCORD SOLUTION FOR INJECTION 250 MG/5 ML ... Faslodex Solution For Injection 250 mg/5ml …

Dihydrocodeine

Dihydrocodeine is an opioid analgesic used as an alternative or adjunct to codeine to treat moderate to severe pain, severe dyspnea, and cough. It is semi-synthetic, and was developed in Germany in 1908 during an international search to find a more effective antitussive agent to help reduce the spread of...
Approved
Illicit
Matched International brands: … DF-118 Forte …
Matched Description: … analgesic used as an alternative or adjunct to codeine to treat moderate to severe pain, severe dyspnea, and ... It is semi-synthetic, and was developed in Germany in 1908 during an international search to find a more …
Matched Mixtures name: … dihydrocodeine bitartrate and aspirin and caffeine DC ... Acetaminophen, Caffeine and Dihydrocodeine Bitartrate ... Dihydrocodeine Bitartrate, Acetaminophen and Caffeine …
Matched Categories: … dihydrocodeine and paracetamol ... dihydrocodeine and acetylsalicylic acid …

Sufentanil

Sufentanil is an opioid analgesic that is used as an adjunct in anesthesia, in balanced anesthesia, and as a primary anesthetic agent. It is administered by the intravenous, epidural and sublingual routes. Also known as Dsuvia, the sublingual form is used for the management of acute pain in adults that...
Approved
Investigational
Matched International brands: … Sufenta Forte …
Matched Description: … It is administered by the intravenous, epidural and sublingual routes. ... Sufentanil is an opioid analgesic that is used as an adjunct in anesthesia, in balanced anesthesia, and ... analgesic in certified medically supervised healthcare settings, including hospitals, surgical centers, and …
Matched Categories: … Fentanyl and fentanyl analogues …

Cilastatin

Cilastatin is an inhibitor of renal dehydropeptidase, an enzyme responsible for both the metabolism of thienamycin beta-lactam antibiotics as well as conversion of leukotriene D4 to leukotriene E4. Since the antibiotic, imipenem, is one such antibiotic that is hydrolyzed by dehydropeptidase, cilastatin is used in combination with imipenem to prevent...
Approved
Investigational
Matched Description: … Cilastatin is an inhibitor of renal dehydropeptidase, an enzyme responsible for both the metabolism of …
Matched Mixtures name: … Imipenem and Cilastatin for Injection ... Imipenem and Cilastatin for Injection ... Imipenem and Cilastatin for Injection USP …
Matched Categories: … imipenem and cilastatin ... imipenem, cilastatin and relebactam …
Matched Products: … IMCIL POWDER FOR SOLUTION FOR INJECTION OR INFUSION 500MG/500MG PER VIAL …

Bortezomib D-mannitol

Approved
Matched Products: … Bortezomib for Injection ... Bortezomib for Injection Sdz …

Ramucirumab

Ramucirumab is a human monoclonal antibody (IgG1) against vascular endothelial growth factor receptor 2 (VEGFR2), a type II trans-membrane tyrosine kinase receptor expressed on endothelial cells. By binding to VEGFR2, ramucirumab prevents binding of its ligands (VEGF-A, VEGF-C, and VEGF-D), thereby preventing VEGF-stimulated receptor phosphorylation and downstream ligand-induced proliferation, permeability,...
Approved
Investigational
Matched Description: … VEGFR stimulation also mediates downstream signalling required for angiogenesis and is postulated to ... , and migration of human endothelial cells. ... By binding to VEGFR2, ramucirumab prevents binding of its ligands (VEGF-A, VEGF-C, and VEGF-D), thereby …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … CYRAMZA CONCENTRATE FOR SOLUTION FOR INFUSION 100MG/10ML ... CYRAMZA CONCENTRATE FOR SOLUTION FOR INFUSION 500MG/50ML ... Cyramza 100mg/10ml concentrate for solution for infusion …

Rituximab

Rituximab is a genetically engineered chimeric murine/human monoclonal antibody directed against the CD20 antigen found on the surface of normal and malignant B lymphocytes. The antibody is an IgG1 kappa immunoglobulin containing murine light and heavy-chain variable region sequences and human constant region sequences , [FDA label]. It was originally...
Approved
Matched Description: … sequences and human constant region sequences [A40017], [FDA label]. ... chimeric murine/human monoclonal antibody directed against the CD20 antigen found on the surface of normal and ... The antibody is an IgG1 kappa immunoglobulin containing murine light and heavy-chain variable region …
Matched Categories: … Amino Acids, Peptides, and Proteins ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Biologics for Rheumatoid Arthritis Treatment …
Matched Products: … Mabthera Concentrate for Solution for Infusion 100mg/10ml ... TRUXIMA® CONCENTRATE FOR SOLUTION FOR INFUSION 10MG/ML ... MABTHERA CONCENTRATE FOR SOLUTION FOR INFUSION 500 mg/50ml …

Tedizolid

Drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and penicillin-resistant Streptococcus penumoniae, represent a massive public health threat.[A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the previously approved linezolid and is generally effective against multidrug-resistant Gram-positive bacteria. Tedizolid is indicated for the...
Approved
Investigational
Matched Description: … Tedizolid is indicated for the treatment of acute bacterial skin and skin structure infections (ABSSSI ... This product is currently available as both an oral tablet and as a powder for intravenous injection. ... ) and is generally more effective and more tolerable than [linezolid]. …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Products: … SIVEXTRO LYOPHILIZED POWDER FOR SOLUTION FOR INFUSION 200MG PER VIAL …
Displaying drugs 651 - 675 of 1113 in total