Displaying drugs 6876 - 6900 of 8179 in total
MVA-SARS-2-S
MVA-SARS-2-S is a COVID-19 vaccine candidate that contains a Modified Vaccinia Virus Ankara (MVA) vector expressing the SARS-CoV-2 spike protein . MVA is a highly attenuated poxvirus vector that has a high-level of biological safety due to its quality of being a non-replicating virus in mammalian hosts and is used...
Investigational
Matched Description: … MVA is a highly attenuated poxvirus vector[A226603] that has a high-level of biological safety due to ... its quality of being a non-replicating virus in mammalian hosts[L30458] and is used to develop vaccines …
Antipain
Antipain is a serine/cysteine protease inhibitor originally isolated from various strains of actinomycetes. Early studies investigated the potential for antipain to alter DNA damage and chromosomal aberrations in irradiated cells or those treated with chemical mutagens such as N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).[A214484, A214487]
Antipain was used in 2010 to obtain a crystal...
Experimental
Matched Description: … Antipain is a serine/cysteine protease inhibitor originally isolated from various strains of actinomycetes ... [A214484, A214487]
Antipain was used in 2010 to obtain a crystal structure of the _Leishmania major ... [A214490] The binding of antipain to OPB has been used in molecular dynamic studies to identify other …
Aminooxyacetic acid
A compound that inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of gamma-aminobutyric acid in tissues. [PubChem]
Experimental
Matched Description: … A compound that inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of …
Glycocholic acid
The glycine conjugate of cholic acid. It acts as a detergent to solubilize fats for absorption and is itself absorbed.
Experimental
Investigational
Matched Description: … The glycine conjugate of cholic acid. …
ALKS 29
ALKS 29 is a new product candidate for the treatment of alcohol dependence. It is being developed by Alkermes, Inc.
Investigational
Matched Description: … ALKS 29 is a new product candidate for the treatment of alcohol dependence. …
LLL-3348
The botanical drug product LLL-3348 is a once-daily oral formulation for treatment of chronic stable plaque type psoriasis.
Investigational
Matched Description: … The botanical drug product LLL-3348 is a once-daily oral formulation for treatment of chronic stable …
Conatumumab
Conatumumab has been used in trials studying the treatment of Sarcoma, Lymphoma, Oncology, Colon Cancer, and Rectal Cancer, among others.
Investigational
Matched Description: … Conatumumab has been used in trials studying the treatment of Sarcoma, Lymphoma, Oncology, Colon Cancer …
Epacadostat
Epacadostat has been used in trials studying the treatment of HL, Melanoma, Glioblastoma, Mucosal Melanoma, and Ovarian Carcinoma, among others.
Investigational
Matched Description: … Epacadostat has been used in trials studying the treatment of HL, Melanoma, Glioblastoma, Mucosal Melanoma …
Basimglurant
Basimglurant has been used in trials studying the diagnostic and treatment of Depression, Fragile X Syndrome, and Major Depressive Disorder.
Investigational
Matched Description: … Basimglurant has been used in trials studying the diagnostic and treatment of Depression, Fragile X Syndrome …
ZD-6126
ZD6126 has been used in trials studying the treatment of Kidney Neoplasms, Colorectal Neoplasms, Metastases, Neoplasm, and Carcinoma, Renal Cell.
Investigational
Matched Description: … ZD6126 has been used in trials studying the treatment of Kidney Neoplasms, Colorectal Neoplasms, Metastases …
AZD-1236
AZD1236 has been used in trials studying the basic science and treatment of Cystic Fibrosis and Chronic Obstructive Pulmonary Disease.
Investigational
Matched Description: … AZD1236 has been used in trials studying the basic science and treatment of Cystic Fibrosis and Chronic …
TAK-448
TAK-448 has been used in trials studying the treatment of Prostate Cancer, Low Testosterone, Prostatic Neoplasms, and Hypogonadotropic Hypogonadism.
Investigational
Matched Description: … TAK-448 has been used in trials studying the treatment of Prostate Cancer, Low Testosterone, Prostatic …
Dinaciclib
Dinaciclib has been used in trials studying the treatment of rrMM, rrCLL, rrDLBCL, Solid Tumors, and Solid Neoplasm, among others.
Investigational
Matched Description: … Dinaciclib has been used in trials studying the treatment of rrMM, rrCLL, rrDLBCL, Solid Tumors, and …
Ganetespib
Ganetespib is under investigation for the treatment of BREAST CANCER, Small Cell Lung Cancer, Acute Myeloid Leukaemia, and Myelodysplastic Syndrome.
Investigational
Matched Description: … Ganetespib is under investigation for the treatment of BREAST CANCER, Small Cell Lung Cancer, Acute Myeloid …
UK-396,082
UK-396,082 has been used in trials studying the basic science of Safety, Phase 1, Toleration, Multiple Dose, and Pharmacokinetic.
Investigational
Matched Description: … UK-396,082 has been used in trials studying the basic science of Safety, Phase 1, Toleration, Multiple …
Eplivanserin
Eplivanserin has been used in trials studying the treatment of Sleep, Insomnia, Chronic Pain, Fibromyalgia, and Primary Insomnia, among others.
Investigational
Matched Description: … Eplivanserin has been used in trials studying the treatment of Sleep, Insomnia, Chronic Pain, Fibromyalgia …
AZD-4547
AZD4547 has been used in trials studying the treatment of Cancer, LYMPHOMA, Gastric Cancer, Adenocarcinoma, and Solid Neoplasm, among others.
Investigational
Matched Description: … AZD4547 has been used in trials studying the treatment of Cancer, LYMPHOMA, Gastric Cancer, Adenocarcinoma …
Derenofylline
Derenofylline has been used in trials studying the treatment of Congestive Heart Failure and Acute Decompensated Heart Failure; Renal Dysfunction.
Investigational
Matched Description: … Derenofylline has been used in trials studying the treatment of Congestive Heart Failure and Acute Decompensated …
WNT-974
WNT974 has been used in trials studying the treatment of Metastatic Colorectal Cancer and Squamous Cell Carcinoma, Head And Neck.
Investigational
Matched Description: … WNT974 has been used in trials studying the treatment of Metastatic Colorectal Cancer and Squamous Cell …
Ozarelix
Ozarelix has been used in trials studying the treatment of Prostate Cancer, Benign Prostatic Hypertrophy, and Benign Prostatic Hyperplasia (BPH).
Investigational
Matched Description: … Ozarelix has been used in trials studying the treatment of Prostate Cancer, Benign Prostatic Hypertrophy …
WP-1066
WP1066 has been used in trials studying the treatment of Melanoma, Brain Cancer, Solid Tumors, and Central Nervous System Neoplasms.
Investigational
Matched Description: … WP1066 has been used in trials studying the treatment of Melanoma, Brain Cancer, Solid Tumors, and Central …
N-sulfoglucosamine sulfohydrolase recombinant
N-sulfoglucosamine sulfohydrolase recombinant is under investigation for the treatment of Mucopolysaccharidosis III and Sanfilippo Syndrome Type A (MPS IIIA).
Investigational
Matched Description: … N-sulfoglucosamine sulfohydrolase recombinant is under investigation for the treatment of Mucopolysaccharidosis …
Condoliase
Condoliase has been used in trials studying the treatment of Lumbar Disc Disease, Lumbar Vertebra Hernia, and Intervertebral Disc Disease.
Investigational
Matched Description: … Condoliase has been used in trials studying the treatment of Lumbar Disc Disease, Lumbar Vertebra Hernia …
Ozanezumab
Ozanezumab has been used in trials studying the treatment of Multiple Sclerosis, Amyotrophic Lateral Sclerosis, and Multiple Sclerosis, Relapsing-Remitting.
Investigational
Matched Description: … Ozanezumab has been used in trials studying the treatment of Multiple Sclerosis, Amyotrophic Lateral …
Emicerfont
Emicerfont has been used in trials studying the diagnostic and treatment of Social Anxiety Disorder and Irritable Bowel Syndrome (IBS).
Investigational
Matched Description: … Emicerfont has been used in trials studying the diagnostic and treatment of Social Anxiety Disorder and …
Displaying drugs 6876 - 6900 of 8179 in total