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Displaying drugs 676 - 700 of 6895 in total
Golimumab
Golimumab is a human IgG1қ monoclonal antibody derived from immunizing genetically engineered mice with human TNFα. Golimumab binds and inhibits soluble and transmembrane human TNFα. Increased TNFα is associated with chronic inflammation. Thus golimumab is indicated for use in adults (i) as an adjunct to methotrexate treatment in patients with...
Approved
Axicabtagene ciloleucel
Axicabtagene ciloleucel is an anti-CD19 chimeric antigen receptor (CAR) T-cell therapy. The drug has a unique mechanism of action, as it utilizes the patient's own T cells, which play a central role in immune response to cancer. Once T-cells are collected from the patient, they are genetically engineered to express...
Approved
Acetazolamide
One of the carbonic anhydrase inhibitors that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is...
Approved
Vet approved
Matched Synonyms: … 2-acetylamino-1,3,4-thiadiazole-5-sulfonamide ... 5-acetamido-1,3,4-thiadiazole-2-sulfonamide ... 5-acetylamino-1,3,4-thiadiazole-2-sulfonamide …
Matched Iupac: … N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide …
Matched Iupac: … N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide …
Oxacillin
An antibiotic similar to flucloxacillin used in resistant staphylococci infections.
Approved
Investigational
Matched Synonyms: … 5-methyl-3-phenyl-4-isoxazolyl-penicillin ... (5-methyl-3-phenyl-4-isoxazolyl)penicillin ... 6β-(5-methyl-3-phenylisoxazol-4-yl)penicillanic acid …
Matched Iupac: … (2S,5R,6R)-3,3-dimethyl-6-(5-methyl-3-phenyl-1,2-oxazole-4-amido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane …
Matched Iupac: … (2S,5R,6R)-3,3-dimethyl-6-(5-methyl-3-phenyl-1,2-oxazole-4-amido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane …
Pantoprazole
Pantoprazole is a first-generation proton pump inhibitor (PPI) used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison (ZE) Syndrome. It can also be...
Approved
Matched Products: … GASPAZOL 40 MG IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ, 5 FLAKON ... Rixubis 1000 IU/5 ml IV Enjeksiyonluk Çözelti Hazırlamak İçin Liyofilize Toz ve Çözücü, 1 adet toz içeren …
Dactylis glomerata pollen
Dactylis glomerata pollen is the pollen of the Dactylis glomerata plant. Dactylis glomerata pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 8 Southern Grass Mix ... 8 Southern Grass Mix ... GRASS MIX Number 4-S …
Bedaquiline
Bedaquiline is a bactericidal antimycobacterial drug belonging to the class of diarylquinoline. The quinolinic central heterocyclic nucleus with alcohol and amine side chains is responsible for bedaquiline-mediated antimycobacterial activity. Although it is closely related to fluoroquinolones, bedaquiline does not affect DNA gyrase; instead, bedaquiline inhibits the c subunit of ATP...
Approved
Matched Synonyms: … 1-(6-Bromo-2-methoxy-quinolin-3-yl)-4-dimethylamino-2-naphthalen-1-yl-1-phenyl-butan-2-ol …
Matched Iupac: … (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol …
Matched Iupac: … (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol …
Irinotecan
Irinotecan is a topoisomerase inhibitor used for chemotherapy. It is a water-soluble analogue of camptothecin, which is extracted from the Chinese tree Camptotheca acuminate. The bis-piperidine side chain in the structure of irinotecan bestows enhanced water solubility. As an anticancer drug, irinotecan was first commercially available in Japan in 1994...
Approved
Investigational
Matched Synonyms: … -9-yl 4-(2-(5-(3-(2,4-dihydroxy-5-isopropylphenyl)-5-hydroxy-4H-1,2,4-triazol-4-yl)-1H-indol-1-yl)ethyl ... (S)-4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin …
Matched Products: … IRINOX 100 MG/5 ML İNFÜZYON İÇİN KONSANTRE ÇÖZELTİ İÇEREN FLAKON, 5 ADET ... CAMPTOLEM 100 MG/ 5 ML ... IRINOTECAN 100 MG / 5 ML …
Matched Products: … IRINOX 100 MG/5 ML İNFÜZYON İÇİN KONSANTRE ÇÖZELTİ İÇEREN FLAKON, 5 ADET ... CAMPTOLEM 100 MG/ 5 ML ... IRINOTECAN 100 MG / 5 ML …
Ritlecitinib
Ritlecitinib (PF-06651600) is a highly selective inhibitor of Janus kinase 3 (JAK3) and the tyrosine kinase expressed in hepatocellular carcinoma (TEC) kinase family. In June 2023, it was approved by the FDA for the treatment of severe alopecia areata in adults and adolescents 12 years and older.[L47092,L47127] It was further...
Approved
Investigational
Matched Synonyms: … 2-propen-1-one, 1-((2S,5R)-2-methyl-5-(7H-pyrrolo(2,3-D)pyrimidin-4-ylamino)-1-piperidinyl)- …
Matched Iupac: … 1-[(2S,5R)-2-methyl-5-({7H-pyrrolo[2,3-d]pyrimidin-4-yl}amino)piperidin-1-yl]prop-2-en-1-one …
Matched Iupac: … 1-[(2S,5R)-2-methyl-5-({7H-pyrrolo[2,3-d]pyrimidin-4-yl}amino)piperidin-1-yl]prop-2-en-1-one …
Gemcitabine
Gemcitabine is a nucleoside analog and a chemotherapeutic agent. It was originally investigated for its antiviral effects, but it is now used as an anticancer therapy for various cancers. Gemcitabine is a cytidine analog with two fluorine atoms replacing the hydroxyl on the ribose. As a prodrug, gemcitabine is transformed...
Approved
Matched Synonyms: … 4-amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one …
Matched Iupac: … 4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one …
Matched Products: … GESITA 200 MG/5 ML IV INFÜZYON IÇIN KONSANTRE ÇÖZELTI IÇEREN FLAKON ,5 ADET ... GEMCITABINA 200 MG/5 ML ... GEMFUL 200 MG/5 ML İ.V. İNFÜZYONLUK KONSANTRE ÇÖZELTİ …
Matched Iupac: … 4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one …
Matched Products: … GESITA 200 MG/5 ML IV INFÜZYON IÇIN KONSANTRE ÇÖZELTI IÇEREN FLAKON ,5 ADET ... GEMCITABINA 200 MG/5 ML ... GEMFUL 200 MG/5 ML İ.V. İNFÜZYONLUK KONSANTRE ÇÖZELTİ …
Leniolisib
Leniolisib is a potent and selective inhibitor of phosphoinositide 3-kinase δ (PI3Kδ). The FDA approved leniolisib on March 24, 2023, making it the first treatment for activated phosphoinositide 3-kinase delta syndrome (APDS). APDS is a primary immunodeficiency caused by mutations in genes encoding the PI3Kδ, thereby increasing the activity of...
Approved
Investigational
Matched Iupac: … 1-[(3S)-3-({6-[6-methoxy-5-(trifluoromethyl)pyridin-3-yl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-4-yl}amino …
Betrixaban
Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa . It was selected among all lead compounds due to its low hERG channel affinity while sustaining its factor Xa inhibition capacity . Betrixaban, now developed by Portola Pharmaceuticals...
Approved
Investigational
Matched Synonyms: … N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide ... N-(5-chloropyridin-2-yl)-2-[[4-(N,N-dimethylcarbamimidoyl)benzoyl]amino]-5-methoxybenzamide …
Matched Iupac: … N-(5-chloropyridin-2-yl)-2-[4-(N,N-dimethylcarbamimidoyl)benzamido]-5-methoxybenzamide …
Matched Iupac: … N-(5-chloropyridin-2-yl)-2-[4-(N,N-dimethylcarbamimidoyl)benzamido]-5-methoxybenzamide …
Promethazine
Promethazine, originally known as 3,277 R.P., is an N-dimethylaminopropyl derivative of phenothiazine that was developed in France in 1946. Promethazine antagonizes a variety of receptors, allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and vomiting.[A189907,A190153,A190159,A190150,A190171]
Promethazine was granted FDA approval before 29...
Approved
Investigational
Matched Salts cas: … 17693-51-5 …
Matched Products: … XEPAGAN-5 ELIXIR 5 mg/5 ml ... PROMAGEN 5 ORAL MIXTURE 5 mg/5 ml ... PROMETHAZINE 5 MG SYRUP 5 mg/5 ml …
Matched Products: … XEPAGAN-5 ELIXIR 5 mg/5 ml ... PROMAGEN 5 ORAL MIXTURE 5 mg/5 ml ... PROMETHAZINE 5 MG SYRUP 5 mg/5 ml …
Furosemide
Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It...
Approved
Vet approved
Matched Synonyms: … 2-Furfurylamino-4-chloro-5-sulfamoylbenzoic acid ... 4-Chloro-5-sulfamoyl-N-furfuryl-anthranilic acid ... 4-Chloro-N-furfuryl-5-sulfamoylanthranilic acid …
Matched Iupac: … 4-chloro-2-{[(furan-2-yl)methyl]amino}-5-sulfamoylbenzoic acid …
Matched Salts cas: … 41733-55-5 …
Matched Mixtures name: … Lasitace 5 mg/40 mg Kapseln ... Lasitace 5 mg/20 mg Kapseln …
Matched Products: … FUROSON 40 MG/4 ML IM/IV AMPUL, 5 ADET ... Lasix 40 mg/4 ml Ampullen ... FUROSON 20 MG/2 ML IM/IV AMPUL, 5 ADET …
Matched Iupac: … 4-chloro-2-{[(furan-2-yl)methyl]amino}-5-sulfamoylbenzoic acid …
Matched Salts cas: … 41733-55-5 …
Matched Mixtures name: … Lasitace 5 mg/40 mg Kapseln ... Lasitace 5 mg/20 mg Kapseln …
Matched Products: … FUROSON 40 MG/4 ML IM/IV AMPUL, 5 ADET ... Lasix 40 mg/4 ml Ampullen ... FUROSON 20 MG/2 ML IM/IV AMPUL, 5 ADET …
Phenylalanine
Phenylalanine is an essential aromatic amino acid that is a precursor of melanin, dopamine, noradrenalin (norepinephrine), and thyroxine.
Approved
Investigational
Nutraceutical
Matched Mixtures name: … AMINOSTERIL N-HEPA 8% ... NUTRINEAL PD-4 PERITONEAL DIALYSIS SOLUTION WITH 1.1% AMINO ACIDS ... NUTRINEAL PD]4 Peritoneal Dialysis Solution with 1.1% Amino Acids …
Idecabtagene vicleucel
Multiple myeloma is a cancer where plasma cells rapidly divide out of control. These cancerous cells generally express the B-cell maturation antigen, while it is rarely expressed on non-cancerous cells. Multiple myeloma is typically treated with an immunomodulatory agent like lenalidomide, a proteasome inhibitor like bortezomib, or an anti-CD38 monoclonal...
Approved
Matched Description: … includes an anti-B-cell maturation antigen scFv-targeting domain, CD3ζ T-cell activation domain, and 4- …
Peppermint
Peppermint allergenic extract is used in allergenic testing.
Approved
Matched Mixtures name: … Bio-strath No. 8 Gouttes …
Pegcetacoplan
Pegcetacoplan is a complement inhibitor indicated in the treatment of paroxysmal nocturnal hemoglobinuria (PNH).[A235000,L34095] Prior to its FDA approval, patients with PNH were typically treated with the C5 inhibiting monoclonal antibody eculizumab. Patients given eculizumab experienced less hemolysis caused by the membrane attack complex, but were still somewhat susceptible to...
Approved
Idebenone
Idebenone is a synthetic analogue of ubiquinone (also known as Coenzyme Q10), a vital cell antioxidant and essential component of the Electron Transport Chain (ETC). It has been proposed that by interacting with the ETC, idebenone increases ATP production required for mitochondrial function, reduces free radicals, inhibits lipid peroxidation, and...
Approved
Investigational
Matched Synonyms: … 6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-p-benzoquinone ... 6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone ... 2,3-dimethoxy-5-methyl-6-(10'-hydroxydecyl)-1,4-benzoquinone …
Matched Mixtures name: … EVERON 90/5 MG FILM KAPLI TABLET ,50 TABLET ... EVERON 90/5 MG FILM KAPLI TABLET ,100 TABLET ... BERMAXIN 90/10/5 MG FILM TABLET ,FILM TABLET, 28 ADET …
Matched Mixtures name: … EVERON 90/5 MG FILM KAPLI TABLET ,50 TABLET ... EVERON 90/5 MG FILM KAPLI TABLET ,100 TABLET ... BERMAXIN 90/10/5 MG FILM TABLET ,FILM TABLET, 28 ADET …
Dorzolamide
Dorzolamide is a non-bacteriostatic sulfonamide derivative and topical carbonic anhydrase (CA) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and ocular hypertension. It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes. Unlike oral CA inhibitors, dorzolamide...
Approved
Matched Synonyms: … (4S,6S)-4-ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic ... (4S,trans)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide ... 4-Ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic acid …
Matched Iupac: … (2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H-1lambda6-thieno[2,3-b]thiopyran-6-sulfonamide …
Matched Mixtures name: … DORZOLAMID/TIMOL MICRO20+5 ... DORZOLAMID/TIMOL MICRO20+5 ... DORZOLAMID/TIMOL MICRO20+5 …
Matched Products: … XOLADOR %2 GÖZ DAMLASI ,5 ML, 1 ŞIŞE …
Matched Iupac: … (2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H-1lambda6-thieno[2,3-b]thiopyran-6-sulfonamide …
Matched Mixtures name: … DORZOLAMID/TIMOL MICRO20+5 ... DORZOLAMID/TIMOL MICRO20+5 ... DORZOLAMID/TIMOL MICRO20+5 …
Matched Products: … XOLADOR %2 GÖZ DAMLASI ,5 ML, 1 ŞIŞE …
Clobetasol propionate
Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors. It has demonstrated superior activity compared to fluocinonide and was first described in the literature in 1974. Clobetasol Propionate was granted FDA approval on 27 December 1985.
Approved
Matched Mixtures name: … Clobetasol Propionate 0.05% / Coal Tar 8% / Salicylic Acid 6% ... Clobetasol Propionate 0.05% / Niacinamide 4% ... Clobetasol Propionate 0.05% / Niacinamide 4% …
Oxaprozin
Oxaprozin is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID), used to relieve the inflammation, swelling, stiffness, and joint pain associated with osteoarthritis and rheumatoid arthritis.
Approved
Matched Iupac: … 3-(4,5-diphenyl-1,3-oxazol-2-yl)propanoic acid …
Matched Salts cas: … 174064-08-5 …
Matched Salts cas: … 174064-08-5 …
Metoclopramide
Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to...
Approved
Investigational
Matched Synonyms: … 2-methoxy-4-amino-5-chloro-N,N-(dimethylaminoethyl)benzamide ... 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-o-anisamide ... 4-amino-5-chloro-2-methoxy-N-(β-diethylaminoethyl)benzamide …
Matched Iupac: … 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide …
Matched Salts cas: … 7232-21-5 …
Matched Products: … METOCLOPRAMIDA 4 MG/ML GOTAS ... METOCLOPRAMIDA 4 MG / ML GOTAS ... METOCLOPRAMIDE SYRUP 5 mg/5 ml …
Matched Iupac: … 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide …
Matched Salts cas: … 7232-21-5 …
Matched Products: … METOCLOPRAMIDA 4 MG/ML GOTAS ... METOCLOPRAMIDA 4 MG / ML GOTAS ... METOCLOPRAMIDE SYRUP 5 mg/5 ml …
Cangrelor
Cangrelor is an intravenous, direct-acting, reversible P2Y12 inhibitor for patients undergoing percutaneous coronary intervention (PCI) who have not been yet treated by oral P2Y12 inhibitors. An advantage Cangrelor provides over oral P2Y12 inhibitors (such as prasugrel, ticagrelor, and clopidogrel) is that it is an active drug not requiring metabolic conversion...
Approved
Matched Synonyms: … [dichloro-[[[(2R,3S,4R,5R)-3,4-dihydroxy-5-[6-(2-methylsulfanylethylamino)-2-(3,3,3-trifluoropropylsulfanyl …
Matched Iupac: … [dichloro({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-{[2-(methylsulfanyl)ethyl]amino}-2-[(3,3,3-trifluoropropyl …
Matched Iupac: … [dichloro({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-{[2-(methylsulfanyl)ethyl]amino}-2-[(3,3,3-trifluoropropyl …
Aprocitentan
Aprocitentan is a dual antagonist of endothelin receptors A and B used for treatment-resistant hypertension. It is the active metabolite of macitentan.
Approximately 10-15% of patients with hypertension have resistant hypertension, defined as uncontrolled high blood pressure despite the combined use of a renin-angiotensin system blocker, a calcium channel blocker,...
Approved
Investigational
Matched Iupac: … N-[5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl]aminosulfonamide …
Displaying drugs 676 - 700 of 6895 in total