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Displaying drugs 676 - 700 of 5087 in total
Ephedrine was first described in western literature in 1888, as a naturally occurring component of the ephedra plant, along with pseudoephedrine. Ephedrine acts as both a direct and indirect sympathomimetic. It is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of norepinephrine from sympathetic neurons,...
Approved
Matched Description: … It is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of ... [A193698] Ephedrine acts as both a direct and indirect sympathomimetic. ... [A193650,L12972] Ephedrine is used for its vasoconstrictive, positive chronotropic, and positive inotropic …
Matched Salts cas: … 1405-94-3
Matched Salts name: … Ephedrine hydrochloride
Matched Categories: … Alpha-and Beta-adrenergic Agonists ... Adrenergic beta-Agonists ... Adrenergic and Dopaminergic Agents ... Alimentary Tract and Metabolism ... Epinephrine and similars …
Matched Products: … Edeline Injection 30 mg/ml ... RINITALMIT LIQUIDE, 30 ML ... EPHEDRINE HYDROCHLORIDE
Experimental
Matched Name: … 3-Amino-3-Oxopropanoic Acid
Matched Iupac: … 2-carbamoylacetic acid
Experimental
Matched Synonyms: … 3-deoxy-α-D-manno-oct-2-ulopyranosonic acid ... α-2-keto-3-deoxyoctulosonic acid pyranose …
Matched Name: … 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid
Matched Iupac: … (2R,4R,5R,6R)-6-[(1R)-1,2-dihydroxyethyl]-2,4,5-trihydroxyoxane-2-carboxylic acid
An inhibitor of nitric oxide synthetase which has been shown to prevent glutamate toxicity. Nitroarginine has been experimentally tested for its ability to prevent ammonia toxicity and ammonia-induced alterations in brain energy and ammonia metabolites. (Neurochem Res 1995:200(4):451-6)
Experimental
Investigational
Matched Synonyms: … omega-Nitroarginine …
Matched Iupac: … (2S)-2-amino-5-(N'-nitrocarbamimidamido)pentanoic acid
Matched Description: … alterations in brain energy and ammonia metabolites. ... Nitroarginine has been experimentally tested for its ability to prevent ammonia toxicity and ammonia-induced …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino …
Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. Their well-characterized anti-inflammatory activity, analgesic property, and established safety record have also made NSAIDs an important tool for optimizing surgical outcomes. Non-ophthalmic formulations of bromfenac were...
Approved
Withdrawn
Matched Synonyms: … 2-amino-3-(4-bromobenzoyl)benzeneacetic acid ... [2-Amino-3-(4-bromo-benzoyl)-phenyl]-acetic acid
Matched Iupac: … 2-[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid
Matched Description: … Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. ... Their well-characterized anti-inflammatory activity, analgesic property, and established safety record …
Matched Salts cas: … 120638-55-3
Methylephedrine is a sympathomimetic amine that appears in various over-the-counter cough and cold medications throughout the world , , . The abuse of methylephedrine-containing medications has been reported in Japan. Methylephedrine is not legally available in the United States, but has been identified in cases of drug abuse .
Approved
Matched International brands: … dl-Methylephedrine Hydrochloride 10% Metal ... dl-Methylephedrine Hydrochloride 10% Maruishi ... dl-Methylephedrine Hydrochloride 10% Sanwa …
Matched Description: … Methylephedrine is a sympathomimetic amine that appears in various over-the-counter cough and cold medications …
Matched Salts name: … DL-Methylephedrine hydrochloride
Investigational
Matched Synonyms: … (3.beta.,22.alpha.,25r)-spirosol-5-en-3-ol ... Solasod-5-en-3.beta.-ol ... Spirosol-5-en-3-ol, (3.beta.,22.alpha.,25r)- …
Atomoxetine is a selective norepinephrine (NE) reuptake inhibitor used for the treatment of attention deficit hyperactivity disorder (ADHD). Also known as the marketed product Strattera, atomoxetine is used with other treatment modalities (psychological, educational, cognitive behaviour therapy, etc) to improve developmentally inappropriate symptoms associated with ADHD including distractibility, short attention...
Approved
Matched Iupac: … methyl[(3R)-3-(2-methylphenoxy)-3-phenylpropyl]amine …
Matched Description: … considered the most effective and first-line treatment for ADHD in adults and children as recommended ... addictive properties, and even amplifies the potency and reinforcing effects of other drugs of abuse ... amphetamines, have a high potential for abuse and dependence. …
Matched Salts name: … Atomoxetine hydrochloride
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … Atomoxetine Hydrochloride ... Atomoxetine hydrochloride ... ATOMOXETIN BETA 10MG …
Gamolenic acid, or gamma-linolenic acid (γ-Linolenic acid) or GLA, is an essential fatty acid (EFA) comprised of 18 carbon atoms with three double bonds that is most commonly found in human milk and other botanical sources . It is an omega-6 polyunsaturated fatty acid (PUFA) also referred to as 18:3n-6;...
Approved
Investigational
Matched Synonyms: … 18:3 (n-6) ... gamoleic acid ... Gamolenic acid
Matched Name: … Gamolenic acid
Matched Iupac: … (6Z,9Z,12Z)-octadeca-6,9,12-trienoic acid
Matched Description: … It is an omega-6 polyunsaturated fatty acid (PUFA) also referred to as 18:3n-6; 6,9,12-octadecatrienoic ... acid; and cis-6, cis-9, cis-12- octadecatrienoic acid [F27]. ... Gamolenic acid, or gamma-linolenic acid (γ-Linolenic acid) or GLA, is an essential fatty acid (EFA) comprised …
Matched Mixtures name: … Beta-carotene 10000I.U. With Borage Oil Cap …
Matched Categories: … Fatty Acids, Omega-6 ... Fatty Acids ... Fatty Acids, Essential ... Fatty Acids, Unsaturated ... gamolenic acid
Lonidamine (LND) is a drug that interferes with energy metabolism of cancer cells, principally inhibiting aerobic glycolytic activity, by its effect on mitochondrially-bound hexokinase (HK). In such way LND could impair energy-requiring processes, as recovery from potentially lethal damage, induced by radiation treatment and by some cytotoxic drugs.
Investigational
Matched Synonyms: … 1-(2,4-dichlorbenzyl)-indazole-3-carboxylic acid ... diclondazolic acid
Matched Iupac: … 1-[(2,4-dichlorophenyl)methyl]-1H-indazole-3-carboxylic acid
Matched Description: … energy-requiring processes, as recovery from potentially lethal damage, induced by radiation treatment and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of acetaminophen overdose.[L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.[A228158,A228163,A228168] Acetylcysteine was granted FDA approval on 14 September 1963.
Approved
Investigational
Matched Synonyms: … (2R)-2-acetylamino-3-sulfanylpropanoic acid ... (R)-2-acetylamino-3-mercaptopropanoic acid ... Mercapturic acid
Matched Iupac: … (2R)-2-acetamido-3-sulfanylpropanoic acid
Matched Description: … Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment …
Matched Mixtures name: … Levomefolate Calcium Acetylcysteine and Mecobalamin Algal ... Levomefolate Calcium, Acetylcysteine, Mecobalamin and Algal ... ASIST C 600 MG-300 MG TOZ IÇEREN SAŞE,30 SAŞE …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Sulfur ... Cough and Cold Preparations …
Matched Products: … XPECTO 300 MG SAŞE, 30 ADET ... N-ACETILCISTEINA 300 MG/3 ML ... SISTECS 300 MG/3 ML ÇÖZELTI, 10 ADET …
Scopolamine is a tropane alkaloid isolated from members of the Solanaceae family of plants, similar to atropine and hyoscyamine, all of which structurally mimic the natural neurotransmitter acetylcholine.[A228423, A228763] Scopolamine was first synthesized in 1959, but to date, synthesis remains less efficient than extracting scopolamine from plants. As an acetylcholine...
Approved
Investigational
Matched Synonyms: … alpha-(Hydroxymethyl)benzeneacetic acid 9-methyl-3-oxa-9-azatricyclo(3.3.1.0(2.4))non-7-yl ester ... 6-beta,7-beta-Epoxy-3-alpha-tropanyl S-(-)-tropate ... (1S,3S,5R,6R,7S)-6,7-Epoxytropan-3-yl (2S)-3-hydroxy-2-phenylpropanoate …
Matched Iupac: … (1R,2R,4S,5S,7S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0^{2,4}]nonan-7-yl (2S)-3-hydroxy-2-phenylpropanoate …
Matched Description: … [A228773, L31578] Scopolamine was first approved by the FDA on December 31, 1979, and is currently ... nervous system and cholinergic signalling. ... tropane alkaloid isolated from members of the _Solanaceae_ family of plants, similar to [atropine] and
Matched Mixtures name: … Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide …
Matched Categories: … Alimentary Tract and Metabolism ... Antiemetics and Antinauseants ... Hypnotics and Sedatives ... Mydriatics and Cycloplegics …
A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
Approved
Matched Synonyms: … 4-(p-bis(beta-chloroethyl)aminophenyl)butyric acid ... Phenylbutyric acid nitrogen mustard ... 4-(p-bis(β-chloroethyl)aminophenyl)butyric acid
Matched Iupac: … 4-{4-[bis(2-chloroethyl)amino]phenyl}butanoic acid
Matched Description: … nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Imipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, imipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, imipramine exerts...
Approved
Matched Synonyms: … 5-[3-(dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine …
Matched Iupac: … (3-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-yl}propyl)dimethylamine …
Matched Description: … and clomipramine. ... TCAs are potent inhibitors of serotonin and norepinephrine reuptake. ... than secondary amine TCAs, such as nortriptyline and desipramine. …
Matched Salts name: … Imipramine hydrochloride
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Heterocyclic Compounds, 3-Ring …
Matched Products: … SILEDX-3 ... Imipramine Hydrochloride ... Imipramine hydrochloride
Procysteine has been used in trials studying the treatment of HIV Infections.
Investigational
Matched Synonyms: … (-)-2-OXO-4-THIAZOLIDINECARBOXYLIC ACID ... (R)-2-OXOTHIAZOLIDINE-4-CARBOXYLIC ACID ... L-2-OXO-4-THIAZOLIDINECARBOXYLIC ACI
Matched Name: … Oxothiazolidinecarboxylic acid
Matched Iupac: … (4R)-2-oxo-1,3-thiazolidine-4-carboxylic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Imino Acids ... Amino Acids, Cyclic …
Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old. Due to concerns about the risk of hepatotoxicity, nimesulide has...
Approved
Investigational
Withdrawn
Matched Description: … primary dysmenorrhoea in adolescents and adults above 12 years old. ... Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and ... Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and
Matched Mixtures name: … FRENAG PLUS JEL, 30 GRAM ... DOLOFAST PLUS %1+%5 JEL, 30 GRAM ... THERMO SULIDIN %1 + %0,025 LIKIT JEL, 30 G …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Matched Products: … AULIN BETA ... NİMEJEL %3 JEL, 30 G ... SULJEL JEL % 3 JEL, 30 G …
Experimental
Matched Synonyms: … (S)-2-amino-3-(3-hydroxy-isoxazol-4-yl)propionic acid
Matched Iupac: … (2S)-2-amino-3-(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)propanoic acid
Ataluren is a novel, orally administered drug that targets nonsense mutations. Ataluren is approved for use by the European Medicines Agency to treat Duchenne Muscular Dystrophy in patients aged 5 years and older who are able to walk. More specifically, ataluren is used in the small group of patients whose...
Approved
Investigational
Matched Synonyms: … 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid
Matched Iupac: … 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid
Matched Description: … use by the European Medicines Agency to treat Duchenne Muscular Dystrophy in patients aged 5 years and ... This drug does not yet have approval by the US Food and Drug Administration or by Health Canada for any …
Experimental
Matched Synonyms: … Adenylyl-(3'-5')-3'-uridylic acid ... Adenylyl-3'-5'-phospho-uridine-3'-monophosphate …
Matched Name: … Adenylyl-(3'-5')-uridine 3'-monophosphate …
Matched Iupac: … yl]oxy}phosphonic acid ... {[(2R,3S,4R,5R)-2-{[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl ... ]oxy}(hydroxy)phosphoryl)oxy]methyl}-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-hydroxyoxolan-3- …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Experimental
Matched Name: … 3-(CARBOXYMETHOXY)THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID
Matched Iupac: … 3-(carboxymethoxy)thieno[2,3-b]pyridine-2-carboxylic acid
Mecapegfilgrastim is under investigation in clinical trial NCT05463601 (Mecapegfilgrastim for the Prevention of Dalpiciclib -Induced Neutropenia in Advanced Breast Cancer).
Investigational
Matched Synonyms: … -.omega. ... .-(((2-((3-(3-((3-aminopropyl)thio)-2,5-dioxo-1-pyrrolidinyl)-1-oxopropyl)amino)ethyl)amino)carbonyl) …
Experimental
Matched Synonyms: … 3-Deoxy-arabino-hexonic acid ... D-2-keto-3-deoxygluconate …
Matched Name: … 3-deoxy-D-arabino-hexonic acid
Matched Iupac: … (2S,4S,5R)-2,4,5,6-tetrahydroxyhexanoic acid
Matched Categories: … Acids, Acyclic ... Hydroxy Acids ... Carboxylic Acids
Alclofenac is a non-steroidal anti-inflammatory drug. It was withdrawn from the market in the United Kingdom in 1979.
Approved
Withdrawn
Matched Synonyms: … [4-(allyloxy)-3-chlorophenyl]acetic acid ... 3-Chloro-4-(2-propenyloxy)benzeneacetic acid ... (4-Allyloxy-3-chlorphenyl)essigsäure …
Matched Iupac: … 2-[3-chloro-4-(prop-2-en-1-yloxy)phenyl]acetic acid
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Acids, Carbocyclic ... Carboxylic Acids ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Investigational
Matched Synonyms: … acid ... acid ... acid
Matched Iupac: … acid ... 2-{3-[(3R)-3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)butoxy]phenyl}acetic …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids
Zorubicin is a drug of the anthracycline class - a class of medications that have historically demonstrated effective chemotherapy for a variety of cancer types.
Experimental
Matched Synonyms: … Benzoic acid hydrazide, 3-hydrazone with daunorubicin …
Matched Salts name: … Zorubicin hydrochloride
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Displaying drugs 676 - 700 of 5087 in total