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Displaying drugs 676 - 700 of 3144 in total
Frexalimab is under investigation in clinical trial NCT06141486 (Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary Progressive Multiple Sclerosis).
Investigational
Matched Synonyms: … Immunoglobulin G1 (272-arginine,325-alanine), anti-(human CD40 ligand) (human-mus musculus monoclonal …
Matched Description: … Frexalimab is under investigation in clinical trial NCT06141486 (Efficacy and Safety Study of Frexalimab …
Iopanoic acid contains iodine and is useful as a contrast medium in cholecystography.
Approved
Withdrawn
Matched Synonyms: … Iopanoic acid ... Iodopanoic acid ... Acidum iopanoicum …
Matched Name: … Iopanoic acid
Matched Iupac: … 2-[(3-amino-2,4,6-triiodophenyl)methyl]butanoic acid
Matched Description: … Iopanoic acid contains iodine and is useful as a contrast medium in cholecystography. …
Matched Categories: … iopanoic acid
Levothyroxine is a synthetically produced form of thyroxine, a major endogenous hormone secreted by the thyroid gland. Also known as L-thyroxine or the brand name product Synthroid, levothyroxine is used primarily to treat hypothyroidism, a condition where the thyroid gland is no longer able to produce sufficient quantities of the...
Approved
Matched Synonyms: … 4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodo-L-phenylalanine ... O-(4-Hydroxy-3,5-diidophenyl)-3,5-diiodo-L-tyrosine ... O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine
Matched Iupac: … (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid
Matched Description: … produce sufficient quantities of the thyroid hormones T4 (tetraiodothyronine or thyroxine) and ... hypothyroidism begin to develop such as fatigue, increased heart rate, depression[A179620], dry skin and ... hair, muscle cramps, constipation, weight gain, memory impairment, and poor tolerance to cold temperatures …
Matched Mixtures name: … Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... levothyroxine sodium and iodine compounds ... Amino Acids
Experimental
Matched Synonyms: … (2S)-2-amino-3-(4-hydroxy-3-nitrophenyl)propanoic acid ... 3-Nitro-L-tyrosine
Matched Name: … 3-nitro-L-tyrosine
Matched Iupac: … (2S)-2-amino-3-(4-hydroxy-3-nitrophenyl)propanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Investigational
Matched Synonyms: … -methyl-l-tryptophan C-11 ... L-tryptophan, .alpha.-(methyl-11c)- …
Phenol is an antiseptic and disinfectant. It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly effective against spores. Phenol has been used to disinfect skin and to relieve itching. Phenol is also used as an oral analgesic or anesthetic in products...
Approved
Experimental
Matched Synonyms: … Acide phénique ... Acide carbolique ... Carbolic acid
Matched Description: … Phenol is an antiseptic and disinfectant. ... Phenol has been used to disinfect skin and to relieve itching. ... It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly …
Matched Mixtures name: … Premier Value Instant Antiseptic Pain Relief ... Major Camphor and Phenol ... CAMPHOR (SYNTHETIC) and PHENOL …
Matched Categories: … Antiseptics and Disinfectants ... Phenol and Derivatives …
Bupropion (also known as the brand name product Wellbutrin®) is a norepinephrine/dopamine-reuptake inhibitor (NDRI) used most commonly for the management of Major Depressive Disorder (MDD), Seasonal Affective Disorder (SAD), and as an aid for smoking cessation. Bupropion exerts its pharmacological effects by weakly inhibiting the enzymes involved in the uptake...
Approved
Matched Description: … [A6399,A178840] Lack of activity at these receptors results in a more tolerable side effect profile; ... commonly for the management of Major Depressive Disorder (MDD), Seasonal Affective Disorder (SAD), and ... effects by weakly inhibiting the enzymes involved in the uptake of the neurotransmitters norepinephrine and
Matched Mixtures name: … Naltrexone Hydrochloride and Bupropion Hydrochloride Extended-Release …
Matched Salts name: … Bupropion hydrochloride
Matched Categories: … bupropion and naltrexone ... Dopamine And Norepinephrine Reuptake Inhibitors ... bupropion and dextromethorphan ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … Bupropion Hydrochloride ... BuPROPion Hydrochloride ... Bupropion hydrochloride
An inhibitor of nitric oxide synthetase which has been shown to prevent glutamate toxicity. Nitroarginine has been experimentally tested for its ability to prevent ammonia toxicity and ammonia-induced alterations in brain energy and ammonia metabolites. (Neurochem Res 1995:200(4):451-6)
Experimental
Investigational
Matched Synonyms: … Ngamma-Nitro-L-arginine ... N(gamma)-nitro-L-arginine
Matched Iupac: … (2S)-2-amino-5-(N'-nitrocarbamimidamido)pentanoic acid
Matched Description: … alterations in brain energy and ammonia metabolites. ... Nitroarginine has been experimentally tested for its ability to prevent ammonia toxicity and ammonia-induced …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Arginine ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino …
Lauric acid is an inexpensive, non-toxic and safe to handle compound often used in laboratory investigations of melting-point depression. Lauric acid is a solid at room temperature but melts easily in boiling water, so liquid lauric acid can be treated with various solutes and used to determine their molecular masses.
Approved
Experimental
Matched Synonyms: … C12 fatty acid ... Dodecoic acid ... Dodecanoic acid
Matched Name: … Lauric acid
Matched Iupac: … dodecanoic acid
Matched Description: … Lauric acid is an inexpensive, non-toxic and safe to handle compound often used in laboratory investigations ... be treated with various solutes and used to determine their molecular masses. ... Lauric acid is a solid at room temperature but melts easily in boiling water, so liquid lauric acid can …
Matched Categories: … Fatty Acids
An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma. (Martindale, The Extra Pharmacopoeia, 30th ed)
Approved
Matched Synonyms: … α-methyl-p-tyrosine ... (–)-α-methyl-L-tyrosine ... α-methyl-L-p-tyrosine
Matched Iupac: … (2S)-2-amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid
Matched Description: … An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Tyrosine Hydroxylase Inhibitors ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
Approved
Investigational
Nutraceutical
Matched Synonyms: … 2-ketopropionic acid ... 2-oxopropanoic acid ... acide pyruvique …
Matched Name: … Pyruvic acid
Matched Iupac: … 2-oxopropanoic acid
Matched Description: … An intermediate compound in the metabolism of carbohydrates, proteins, and fats. ... In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous …
Matched Categories: … Keto Acids ... Carboxylic Acids
Experimental
Matched Synonyms: … Glycine amide …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids
The phosphoric acid ester of serine.
Experimental
Matched Synonyms: … Serine phosphate …
Matched Iupac: … (2S)-2-amino-3-(phosphonooxy)propanoic acid
Matched Description: … The phosphoric acid ester of serine. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Neutral ... Phosphoamino Acids
Experimental
Matched Synonyms: … Arginine L-aspartate ... L-Arginine aspartate ... L-Arginine-L-aspartate …
Matched Name: … Arginine aspartate …
Matched Iupac: … (2S)-2-amino-5-carbamimidamidopentanoic acid; (2S)-2-aminobutanedioic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino …
Levoleucovorin is the enantiomerically active form of Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin). Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the levo-isomer has been shown to be...
Approved
Investigational
Matched Synonyms: … N-[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic ... acid ... L-Folinic acid
Matched Iupac: … -amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid
Matched Description: … and methionine before incorporation into DNA or protein. ... This important pathway, which is required for de novo synthesis of nucleic acids and amino acids, is ... acid or leucovorin). …
Matched Categories: … Folic Acid and Derivatives ... Enzymes and Coenzymes ... Folic Acid Analogues …
Bufexamac is a non-steroidal anti-inflammatory drug (NSAID) under the market name Droxaryl, Malipuran, Paraderm and Parfenac. It is typically administered topically for the treatment of subacute and chronic eczema of the skin, including atopic eczema and other inflammatory dermatoses, as well as sunburn and other minor burns, and itching. It...
Approved
Withdrawn
Matched Synonyms: … Bufexamic acid ... 2-(p-Butoxyphenyl)-acetohydroxamic acid ... 4-Butoxyphenylacetohydroxamic acid
Matched Description: … and itching. ... a non-steroidal anti-inflammatory drug (NSAID) under the market name Droxaryl, Malipuran, Paraderm and ... including atopic eczema and other inflammatory dermatoses, as well as sunburn and other minor burns, …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain ... Hydroxy Acids
Experimental
Matched Synonyms: … (2S)-1-((2R)-2-Methyl-3-sulfanylpropanoyl)pyrrolidine-2-carboxylic acid ... 2-D-Methyl-3-mercaptopropanoyl-L-proline
Matched Iupac: … (2S)-1-[(2R)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Imino Acids ... Amino Acids, Cyclic …
Investigational
Matched Synonyms: … Glycine, L-prolyl-L-prolyl-L-leucyl-L-seryl-L-glutaminyl-L-alpha-glutamyl-L-threonyl-Lphenylalanyl- L-seryl-L-alpha-aspartyl-L-leucyl-L-tryptophyl-L-lysyl-L-leucyl-L-leucyl-L-lysyl-Llysyl ... - L-tryptophyl-L-lysyl-L-methionyl-L-arginyl-L-arginyl-L-asparaginy …
A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
Experimental
Investigational
Matched Synonyms: … Butanoic acid ... Butyricum acidum ... N-butyric acid
Matched Name: … Butyric Acid
Matched Iupac: … butanoic acid
Matched Description: … A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the …
Matched Categories: … Histamine Agents ... Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class, chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking dopamine receptors. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
Approved
Investigational
Vet approved
Matched Description: … Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the …
Matched Salts name: … Chlorpromazine hydrochloride
Matched Categories: … Histamine Antagonists ... Histamine H1 Antagonists …
Matched Products: … PROZIN ... Chlorpromazine Hydrochloride ... Chlorpromazine hydrochloride
Investigational
Matched Synonyms: … L-glutamic acid, n-(4-(3-amino-1,2,5,6,6a,7-hexahydro-1-oxoimidazo(1,5-f)pteridin-8(9h)-yl)benzoyl)- ... 5,10-methylene-(6rs)-tetrahydrofolic acid ... 5,10-methylenetetrahydrofolic acid
Matched Iupac: … 4-{3-amino-1-oxo-1H,2H,5H,6H,6aH,7H,8H,9H-imidazo[1,5-f]pteridin-8-yl}phenyl)formamido]pentanedioic acid
Matched Categories: … Enzymes and Coenzymes …
Experimental
Matched Synonyms: … Phenylalanine amide ... L-phenylalanine amide …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Captopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Captopril may be used in the treatment of hypertension.
Approved
Matched Synonyms: … (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid ... D-2-methyl-3-mercaptopropanoyl-L-proline ... D-3-mercapto-2-methylpropanoyl-L-proline
Matched Iupac: … (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid
Matched Description: … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS …
Matched Mixtures name: … Captopril and Hydrochlorothiazide ... Captopril and Hydrochlorothiazide ... Captopril and Hydrochlorothiazide …
Matched Categories: … Amino Acids, Peptides, and Proteins ... ACE Inhibitors and Diuretics ... captopril and diuretics ... Amino Acids ... Imino Acids
Matched Products: … HISTIDIN C CAPTOPRIL ITALMEX ... HISTIDIN C (CAPTOPRIL) TABLETAS 50 MG …
Approved
Experimental
Matched Synonyms: … Zirconium hydroxychloride ... Zirconyl hydroxychloride
A synthetic anti-inflammatory glucocorticoid derived from cortisone. It is biologically inert and converted to prednisolone in the liver. Prednisone was granted FDA approval on 21 February 1955.
Approved
Vet approved
Matched Description: … [A187463] It is biologically inert and converted to [prednisolone] in the liver. …
Matched Categories: … Alimentary Tract and Metabolism ... Prednisolone and Prodrugs ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … PREDNISON ACIS 5MG ... PREDNISON ACIS 20MG ... PREDNISON ACIS 50MG …
Displaying drugs 676 - 700 of 3144 in total