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Displaying drugs 7076 - 7100 of 7910 in total
Indatraline is a nonselective monoamine reuptake inhibitor.
Investigational
Matched Synonyms: … (+/-)-trans-3-(3,4-dichlorophenyl)-n-methyl-1-indanamine …
Matched Iupac: … (1R,3S)-3-(3,4-dichlorophenyl)-N-methyl-2,3-dihydro-1H-inden-1-amine …
Matched Description: … Indatraline is a nonselective monoamine reuptake inhibitor.[A253022] …
Matched Salts cas: … 96850-13-4
Lomvastomig is under investigation in clinical trial NCT04785820 (A Study of Lomvastomig (RO7121661) and Tobemstomig (RO7247669) Compared With Nivolumab in Participants With Advanced or Metastatic Squamous Cell Carcinoma of the Esophagus).
Investigational
Matched Synonyms: … Anti-pd-1/tim-3 bispecific antibody ro7121661 …
Matched Description: … and Tobemstomig (RO7247669) Compared With Nivolumab in Participants With Advanced or Metastatic Squamous ... Lomvastomig is under investigation in clinical trial NCT04785820 (A Study of Lomvastomig (RO7121661) …
MMDA, or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant and psychedelic properties. It also acts as an entheogen and an entactogen. MMDA bears resemblance to the psychopharmacologically active essential oils elemicin and myristicin found in nutmeg. The effects of MMDA includes feelings of euphoria and warmth,...
Experimental
Illicit
Matched Synonyms: … 5-Methoxy-3,4-methylenedioxyamphetamine ... 3-Methoxy-4,5-methylenedioxyphenylisopropylamine ... 3-Methoxy-alpha-methyl-4,5-methylenedioxyphenethylamine …
Matched Iupac: … 1-(7-methoxy-2H-1,3-benzodioxol-5-yl)propan-2-amine …
Matched Description: … The effects of MMDA includes feelings of euphoria and warmth, as well as realistic closed-eye visuals ... MMDA, or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant ... It also acts as an entheogen and an entactogen. …
Matched Categories: … Serotonin 5-HT2 Receptor Agonists ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
8-azaguanine is one of the early purine analogs showing antineoplastic activity. It functions as an antimetabolite and is easily incorporated into ribonucleic acids.
Experimental
Matched Synonyms: … 8 AG ... 3-amino-2,4,7,8,9-pentazabicyclo[4.3.0]nona-1,3,6-trien-5-one …
Matched Iupac: … 5-amino-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one …
Matched Description: … It functions as an antimetabolite and is easily incorporated into ribonucleic acids. …
Matched Categories: … Aza Compounds ... Heterocyclic Compounds, 2-Ring ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates …
Tibolone is a synthetic steroid hormone drug, which is mainly non-selective in its binding profile, acting as an agonist primarily at estrogen receptors (ER), with a preference for ER alpha . Tibolone (Livial, Org OD 14), produced by Organon (West Orange, NJ), is a synthetic steroid that possesses estrogenic, androgenic...
Approved
Investigational
Matched Synonyms: … 17-hydroxy-7alpha-methyl-19-nor-17alpha-pregn-5(10)-en-20-yn-3-one …
Matched Iupac: … -en-5-one ... (1S,9R,10R,11S,14R,15S)-14-ethynyl-14-hydroxy-9,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-2(7) …
Matched Description: … Tibolone (Livial, Org OD 14), produced by Organon (West Orange, NJ), is a synthetic steroid that possesses ... Tibolone is approved in 90 countries to manage menopausal symptoms and in 45 countries to prevent the ... as an agonist primarily at estrogen receptors (ER), with a preference for ER alpha [L1874]. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Estrogens, Antiestrogens, and Estrogen Agonist-Antagonists ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … LADYBON 2.5 MG TABLET, 28 ADET ... LIVIAL 2.5 MG TABLET, 28 ADET ... LIVIAL TABLET 2.5 mg …
Manganese is a transition metal that was first described in the 19th and 20th centuries. It is environmentally abundant, being the fifth most abundant metal and the twelfth most abundant element overall on Earth.[A263657, A263667] Manganese intake primarily occurs through the diet, as it is found at low levels in...
Approved
Nutraceutical
Matched Synonyms: … MANGANESE(2+) ... MANGANESE ION(2+) ... MANGANESE CATION (2+) …
Matched Iupac: … manganese(2+) ion …
Matched Description: … [A263687, A263662] In humans, manganese regulates several physiological processes by acting as a cofactor ... [A263657] Manganese can be found in over-the-counter nutritional supplements and vitamins. ... [L50667] Apart from its use in human health, has been used in the mining industry, welding, smelting, …
Matched Salts cas: … 7773-01-5 ... 10034-96-5
Matched Mixtures name: … Trace Minerals Et/and B12 Tab ... Calcium and Magnesium 1:1 Plus Tablets ... Magnum-75 Vitamin and Mineral Supplement …
Matched Categories: … Diet, Food, and Nutrition …
Matched Products: … Bio-plex Tab 0.95mg ... Ostrophin Pmg Tab 4mg ... Chelated Manganese Tablets - 5mg
Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin when administered as an implant delivering continuous therapeutic doses. This drug is a synthetic analog of naturally occurring GnRH with a higher potency. Histrelin implants are non-biodegradable, diffusion-controlled, hydrogel polymer reservoirs containing histrelin acetate that...
Approved
Withdrawn
Matched Synonyms: … [(im-Bzl)-D-His6,Pro9-NEt]-gonadotropin releasing hormone ... 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-1-benzyl-D-histidyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide ... 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-Nτ-benzyl-D-histidyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide …
Matched Iupac: … 3-(1H-imidazol-4-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido ... ]-N-ethylpyrrolidine-2-carboxamide; bis(acetic acid) ... (2S)-1-[(2S)-2-[(2S)-2-[(2R)-3-(1-benzyl-1H-imidazol-4-yl)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)- ... ]propanamido]-3-(4-hydroxyphenyl)propanamido]propanamido]-4-methylpentanamido]-5-carbamimidamidopentanoyl …
Matched Description: … (CPP) due to their capacity to reduce LH levels and the concentration of sex steroids. ... histrelin acetate that need to be replaced every 52 weeks. ... [L41715] Vantas was later discontinued by Endo Pharmaceuticals Inc. on September 21, 2021. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones and Related Agents ... Antineoplastic and Immunomodulating Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Pyrrolizidine is under investigation in clinical trial NCT05898373 (Vedicitumomab Alone or in Combination for the Treatment of Locally Advanced or Metastatic SDC).
Investigational
Matched Synonyms: … 1-azabicyclo(3.3.0)octane ... 1h-pyrrolizine, hexahydro- …
Experimental
Matched Synonyms: … Nickel(2+) ... Nickel ion(2+) ... Nickel(2+) ion …
Matched Iupac: … nickel(2+) ion …
A pyrazine that is used therapeutically as an antitubercular agent.
Approved
Investigational
Matched Synonyms: … 2-carbamylpyrazine ... 2-pyrazinecarboxamide ... pyrazine-2-carboxamide …
Matched Iupac: … pyrazine-2-carboxamide …
Matched Description: … A pyrazine that is used therapeutically as an antitubercular agent. …
Matched Mixtures name: … RIFAMPICIN 150 MG/ISONIAZID 75 MG/PYRAZINAMIDE 400 MG/ETHAMBUTOL 275 MG ... RIFAMPICINA 150 MG+ ISONIAZIDA 75 MG + PIRAZINAMIDA 400 MG+ ETAMBUTOL CLORHIDRATO 275 MG TABLETAS RECUBIERTAS ... ไรฟาโฟร์ อี -275
Matched Categories: … rifampicin, pyrazinamide and isoniazid ... rifampicin, pyrazinamide, ethambutol and isoniazid ... Heterocyclic Compounds, 1-Ring ... Drugs that are Mainly Renally Excreted …
Matched Products: … PIRAZINAMIDA TABLETAS BP 500 MG. ... PİRAZİNİD 500 MG TABLET, 200 ADET ... AFT-Pyrazinamide Tablet 500mg …
Experimental
Matched Name: … 1-(CYCLOHEXYLAMINO)-3-(6-METHYL-3,4-DIHYDRO-1H-CARBAZOL-9(2H)-YL)PROPAN-2-OL …
Matched Iupac: … (2S)-1-(cyclohexylamino)-3-(6-methyl-2,3,4,9-tetrahydro-1H-carbazol-9-yl)propan-2-ol …
Experimental
Matched Name: … 6-amino-2-[(1-naphthylmethyl)amino]-3,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one …
Matched Iupac: … 6-amino-2-{[(naphthalen-1-yl)methyl]amino}-3H,7H,8H-imidazo[4,5-g]quinazolin-8-one …
Lutropin alfa is a recombinant human luteinizing hormone produced in yeast with 2 subunits, alpha = 92 residues, beta = 121 residues. It is a heterodimeric glycoprotein made up of monomeric units. Lutropin alfa was the first and only recombinant human form of luteinizing hormone (LH) developed for use in...
Approved
Matched Description: … Lutropin alfa was the first and only recombinant human form of luteinizing hormone (LH) developed for ... Lutropin alfa is a recombinant human luteinizing hormone produced in yeast with 2 subunits, alpha = 92 ... surge, in females triggers ovulation and the development of the corpous luteum. …
Matched Mixtures name: … Pergoveris 150IU/75IU powder and solvent for solution for injection ... Pergoveris Powder and Solvent for Solution for Injection 150iu/75iu ... PERGOVERIS 150 IU/75 IU ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gonadotropins and Antigonadotropins ... Sex Hormones and Modulators of the Genital System …
Matched Products: … LUVERIS 75 IU ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET ... LUVERIS 75 IU ... LUVERIS FOR INJECTION 75 iu/vial (Revised formula) …
Nelarabine is an antineoplastic agent that is typically used to treat acute T-cell lymphoblastic leukemia, particularly T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LBL), in both adult and pediatric patients whose disease has not responded to or has relapsed following at least two chemotherapy regimens. T-cell acute lymphoblastic...
Approved
Investigational
Matched Synonyms: … 2-Amino-9-beta-D-arabinofuranosyl-6-methoxy-9H-purine …
Matched Iupac: … (2R,3S,4S,5R)-2-(2-amino-6-methoxy-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol …
Matched Description: … [A258719] Nelarabine was first granted accelerated approval by the FDA on October 28, 2005, and was ... only 20 to 25% of patients diagnosed with acute lymphoblastic leukemia and 1.7% of patients diagnosed ... nelarabine can yield a 13% complete response (CR) rate in pediatric patients and 18% in adult patients …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … NELARAMAX 250 MG/50 ML IV İNFÜZYONLUK ÇÖZELTİ , 1 ADET ... NELARAMAX 250 MG/50 ML IV İNFÜZYONLUK ÇÖZELTİ , 6 ADET …
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19), which is a respiratory disease that is capable of progressing to viral pneumonia and acute respiratory distress syndrome (ARDS); COVID-19 can be fatal. Like other RNA viruses, SARS-CoV-2 depends on an RNA-dependent RNA polymerase...
Approved
Investigational
Matched Iupac: … 2-ethylbutyl (2S)-2-{[(S)-{[(2R,3S,4R,5R)-5-{4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl}-5-cyano-3,4-dihydroxyoxolan ... -2-yl]methoxy}(phenoxy)phosphoryl]amino}propanoate …
Matched Description: … 2019 (COVID-19), which is a respiratory disease that is capable of progressing to viral pneumonia and ... _, _Paramyxoviridae_, _Pneumoviridae_, and _Coronaviridae_ viral families. ... 2 and the related SARS-CoV and MERS-CoV,[A222398] and has been investigated in multiple COVID-19 clinical …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Nucleosides and Nucleotides ... Nucleic Acids, Nucleotides, and Nucleosides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors ... MATE 1 Inhibitors …
Matched Products: … VEKLURY 100 MG İNFÜZYONLUK ÇÖZELTİ KONSANTRESİ İÇİN TOZ, 1 ADET …
Ursodeoxycholic acid (UDCA), also known as ursodiol, is a naturally-occurring bile acid that constitutes a minor fraction of the human bile acid pool.[A256272,A256277] UDCA has been used to treat liver disease for decades: its first use in traditional medicine dates back more than a hundred years.[A256267,A256463] UDCA was first characterized...
Approved
Investigational
Matched Synonyms: … (3α,,)-3,7-dihydroxycholan-24-oic acid ... 3alpha,7beta-Dihydroxy-5beta-cholan-24-oic acid ... (3alpha,5beta,7beta)-3,7-dihydroxycholan-24-oic acid …
Matched Iupac: … (4R)-4-[(1R,3aS,3bR,4S,5aS,7R,9aS,9bS,11aR)-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta ... [a]phenanthren-1-yl]pentanoic acid …
Matched Description: … [A256267,A256463] UDCA was first characterized in the bile of the Chinese black bear and is formed by ... [A256272] UDCA was first approved by the FDA in 1987 for dissolution of gallstones and for primary ... a minor fraction of the human bile acid pool. …
Matched Categories: … Bile Acids and Salts ... Bile and Liver Therapy ... Alimentary Tract and Metabolism ... Bile acids and derivatives ... Cholagogues and Choleretics …
Matched Products: … URSOKOL 750 MG FİLM TABLET, 50 ADET ... URSOKOL 750 MG FİLM TABLET, 100 ADET ... URSOVEF 750 MG FILM KAPLI TABLET, 100 ADET …
Experimental
Matched Name: … (1S,4S,5S)-1,4,5-TRIHYDROXY-3-[3-(PHENYLTHIO)PHENYL]CYCLOHEX-2-ENE-1-CARBOXYLIC ACID …
Matched Iupac: … (1R,4R,5R)-1,4,5-trihydroxy-3-[3-(phenylsulfanyl)phenyl]cyclohex-2-ene-1-carboxylic acid …
Approved
Investigational
Matched Mixtures name: … Plasma-lyte 56 and Dextrose ... Normosol-M and Dextrose ... Normosol-M and Dextrose …
Matched Categories: … Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Drugs that are Mainly Renally Excreted …
Matched Products: … DBL POTASSIUM ACETATE CONCENTRATED INJECTION 2.45 g/5 ml …
A homolog of ergonovine containing one more CH2 group. (Merck Index, 11th ed)
Approved
Matched Synonyms: … D-lysergic acid 1-butanolamide ... 9,10-Didehydro-N-[1-(hydroxymethyl)-propyl]-D-lysergamide …
Matched Iupac: … (4R,7R)-N-[(2S)-1-hydroxybutan-2-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1 ... (16),2,9,12,14-pentaene-4-carboxamide …
Matched Description: … A homolog of ergonovine containing one more CH2 group. (Merck Index, 11th ed) …
Matched Categories: … Ergot Alkaloids and Derivatives ... methylergometrine and oxytocin ... Genito Urinary System and Sex Hormones ... Cytochrome P-450 CYP3A Inhibitors ... Cytochrome P-450 Substrates …
Matched Products: … UTERJİN 0,2 MG IM AMPUL, 100 ADET ... METILER 0,25 MG/ML DAMLA, ÇÖZELTİ, 10 ML ... UTERJIN 20 DRAJE …
Investigational
Matched Synonyms: … N,N-Diethyl-8,8-dipropyl-2-azaspiro(4.5)decane-2-propanamine …
Matched Iupac: … (3-{8,8-dipropyl-2-azaspiro[4.5]decan-2-yl}propyl)diethylamine …
Matched Salts cas: … 183063-72-1
Hydroxystilbamidine isethionate is used in the therapy of some patients with nonprogressive blastomycosis of the skin, and pulmonary or systemic blastomycosis in children, with fewer side effects than amphotericin B. Hydroxystilbamidine isethionate is also used in pathology for diagnostic purposes.
Approved
Matched Synonyms: … 2-Hydroxy-4,4'-diguanylstilbene ... 2-Hydroxy-4,4'-stilbenedicarboxamidine …
Matched Iupac: … 4-[(1E)-2-(4-carbamimidoylphenyl)ethenyl]-3-hydroxybenzene-1-carboximidamide …
Matched Description: … isethionate is used in the therapy of some patients with nonprogressive blastomycosis of the skin, and ... pulmonary or systemic blastomycosis in children, with fewer side effects than amphotericin B. …
Matched Salts cas: … 533-22-2
Verteporfin, marketed as Visudyne, is a benzoporphyrin derivative comprising a 50:50 mixture of two isomers: CL-315555 and CL-315585. It is used as a photosensitizer in photodynamic therapy to eliminate abnormal blood vessels in wet form macular degeneration. Verteporfin accumulates in these abnormal blood vessels and, when stimulated by nonthermal red...
Approved
Investigational
Matched Description: … : [CL-315555] and [CL-315585]. ... Verteporfin accumulates in these abnormal blood vessels and, when stimulated by nonthermal red light ... Verteporfin, marketed as Visudyne, is a benzoporphyrin derivative comprising a 50:50 mixture of two isomers …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings ... Heterocyclic Compounds, 1-Ring …
Matched Products: … VISUDYNE FOR INJECTION 15 mg/vial ... VISUDYNE INFÜZYON SOLÜSYONU İÇİN TOZ, 1 ADET ... VISUDYNE 15 MG INFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ …
Investigational
Matched Synonyms: … -OCTADECAOXA-57-AZA-19,39-DIPHOSPHAOCTAPENTACONT-1-YL HYDR ... -CHOLEST-5-EN-3-YLOXY)-19,39,42-TRIHYDROXY-19,39-DIOXIDO-58-OXO-3,6,9,12,15,18,20,23,26,29,32,35,38,40,44,47,50,53 ... DNA, D(P-THIO)(T-C-G-T-C-G-T-T-T-T-G-T-C-G-T-T-T-T-G-T-C-G-T-T), 3'-(58-((3.BETA.) …
Experimental
Matched Synonyms: … 2-Methylpropanoate ... 2-methyl-propionic acid ... 2-Methylpropionsäure …
Matched Iupac: … 2-methylpropanoic acid …
Methylphenidate is a central nervous system stimulant used most commonly in the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) and for narcolepsy. Also known as the marketed products Ritalin, Concerta, or Biphentin, methylphenidate is used with other treatment modalities (psychological, educational, cognitive behaviour therapy, etc) to improve the following group of developmentally...
Approved
Investigational
Matched Synonyms: … methyl phenyl(piperidin-2-yl)acetate ... methyl α-phenyl-α-(2-piperidyl)acetate ... methyl α-phenyl-α-2-piperidinylacetate …
Matched Iupac: … methyl 2-phenyl-2-(piperidin-2-yl)acetate …
Matched Description: … gene (DAT1), the D4 receptor gene (DRD-4), and/or the D2 receptor gene that may be at least partly overcome ... Oral Delivery (OROS) system where 22% of the dose is provided as an immediate release and 78% is provided ... system (MLRTM) where 40% of the dose is provided as an immediate release and 60% is provided through …
Matched Salts cas: … 23655-65-4
Matched Categories: … Methylphenidate and isomer ... Respiratory and CNS Stimulants ... Psychostimulants, Agents Used for ADHD and Nootropics ... Heterocyclic Compounds, 1-Ring …
Matched Products: … Bar-methylphenidate HCl CR ... Apo-methylphenidate ER ... Act Methylphenidate ER
Displaying drugs 7076 - 7100 of 7910 in total