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Displaying drugs 701 - 725 of 5178 in total
Rutin
A flavonol glycoside found in many plants, including buckwheat; tobacco; forsythia; hydrangea; viola, etc. It has been used therapeutically to decrease capillary fragility.
Approved
Experimental
Investigational
Matched Synonyms: … 3-[[6-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy ... 3-Rutinosyl quercetin ... Quercetin 3-rutinoside …
Matched Iupac: … 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5 ... -trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-4H-chromen-4-one …
Matched Description: … A flavonol glycoside found in many plants, including buckwheat; tobacco; forsythia; hydrangea; viola, …
Matched Salts cas: … 250249-75-3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5 ... -trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-4H-chromen-4-one …
Matched Description: … A flavonol glycoside found in many plants, including buckwheat; tobacco; forsythia; hydrangea; viola, …
Matched Salts cas: … 250249-75-3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Aminoglutethimide
An aromatase inhibitor that produces a state of "medical" adrenalectomy by blocking the production of adrenal steroids. It also blocks the conversion of androgens to estrogens. Aminoglutethimide has been used in the treatment of advanced breast and prostate cancer. It was formerly used for its weak anticonvulsant properties. (From Martindale,...
Approved
Investigational
Matched Synonyms: … 2-(p-Aminophenyl)-2-ethylglutarimide ... 3-Ethyl-3-(p-aminophenyl)-2,6-dioxopiperidine …
Matched Iupac: … 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione …
Matched Description: … Aminoglutethimide has been used in the treatment of advanced breast and prostate cancer. ... An aromatase inhibitor that produces a state of "medical" adrenalectomy by blocking the production of …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Iupac: … 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione …
Matched Description: … Aminoglutethimide has been used in the treatment of advanced breast and prostate cancer. ... An aromatase inhibitor that produces a state of "medical" adrenalectomy by blocking the production of …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Bronopol
Bronopol, or 2-Bromo-2-nitro-1,3-propanediol, is an organic compound with wide-spectrum antimicrobial properties. First synthesized in 1897, bronopol was primarily used as a preservative for pharmaceuticals and was registered in the United States in 1984 for use in industrial bactericides, slimicides and preservatives . Bronopol is used as a microbicide or microbiostat...
Approved
Matched Synonyms: … 2-Bromo-2-nitropropane-1,3-diol ... 2-Nitro-2-bromo-1,3-propanediol …
Matched Iupac: … 2-bromo-2-nitropropane-1,3-diol …
Matched Description: … Bronopol, or 2-Bromo-2-nitro-1,3-propanediol, is an organic compound with wide-spectrum antimicrobial ... First synthesized in 1897, bronopol was primarily used as a preservative for pharmaceuticals and was ... Bronopol is used as a microbicide or microbiostat in various commercial and industrial applications, …
Matched Categories: … Indicators and Reagents ... Compounds used in a research, industrial, or household setting …
Matched Iupac: … 2-bromo-2-nitropropane-1,3-diol …
Matched Description: … Bronopol, or 2-Bromo-2-nitro-1,3-propanediol, is an organic compound with wide-spectrum antimicrobial ... First synthesized in 1897, bronopol was primarily used as a preservative for pharmaceuticals and was ... Bronopol is used as a microbicide or microbiostat in various commercial and industrial applications, …
Matched Categories: … Indicators and Reagents ... Compounds used in a research, industrial, or household setting …
Bromotheophylline
Bromotheophylline is the active moiety of pamabrom, a mixture of 2-amino-2-methyl-propanol and bromotheophylline. From this mixture, bromotheophylline acts as a weak diuretic that has been used along with some analgesics to relieve the symptoms of premenstrual syndrome. Bromotheophylline is categorized on the FDA as a drug substance with an inactive...
Approved
Matched Description: … Bromotheophylline is the active moiety of pamabrom, a mixture of 2-amino-2-methyl-propanol and bromotheophylline ... [L1082] It is also approved by Health Canada to be used alone or in combination with [DB00316] in OTC ... [A33018] Bromotheophylline is categorized on the FDA as a drug substance with an inactive state since …
Matched Salts cas: … 606-04-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Salts cas: … 606-04-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Cefotiam
One of the cephalosporins that has a broad spectrum of activity against both gram-positive and gram-negative microorganisms.
Approved
Investigational
Matched Synonyms: … (6R,7R)-7-[2-(2-Amino-thiazol-4-yl)-acetylamino]-3-[1-(2-dimethylamino-ethyl)-1H-tetrazol-5-ylsulfanylmethyl ... ]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … (6R,7R)-7-[2-(2-amino-1,3-thiazol-4-yl)acetamido]-3-[({1-[2-(dimethylamino)ethyl]-1H-1,2,3,4-tetrazol ... -5-yl}sulfanyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … One of the cephalosporins that has a broad spectrum of activity against both gram-positive and gram-negative …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … (6R,7R)-7-[2-(2-amino-1,3-thiazol-4-yl)acetamido]-3-[({1-[2-(dimethylamino)ethyl]-1H-1,2,3,4-tetrazol ... -5-yl}sulfanyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … One of the cephalosporins that has a broad spectrum of activity against both gram-positive and gram-negative …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Nefazodone
Nefazodone hydrochloride (trade name Serzone) is an antidepressant drug marketed by Bristol-Myers Squibb. Its sale was discontinued in 2003 in some countries, due to the small possibility of hepatic (liver) injury. Drug-induced hepatic injuries were associated with an risk of elevated need for a liver transplant, or even death, with...
Approved
Withdrawn
Matched Synonyms: … 1-(3-(4-(m-Chlorophenyl)-1-piperazinyl)propyl)-3-ethyl-4-(2-phenoxyethyl)-delta2-1,2,4-triazolin-5-one …
Matched Iupac: … 1-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-3-ethyl-4-(2-phenoxyethyl)-4,5-dihydro-1H-1,2,4-triazol …
Matched Description: … Drug-induced hepatic injuries were associated with an risk of elevated need for a liver transplant, or …
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors ... Serotonin antagonist and reuptake inhibitors (SARIs) …
Matched Iupac: … 1-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-3-ethyl-4-(2-phenoxyethyl)-4,5-dihydro-1H-1,2,4-triazol …
Matched Description: … Drug-induced hepatic injuries were associated with an risk of elevated need for a liver transplant, or …
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors ... Serotonin antagonist and reuptake inhibitors (SARIs) …
Rabies virus inactivated antigen, B
Inactivated rabies virus antigen B is a component of rabies vaccines used for pre- and post-exposure prophylaxis against rabies.
Approved
Matched Description: … Inactivated rabies virus antigen B is a component of rabies vaccines used for pre- and post-exposure …
Matched Categories: … Immune Sera and Immunoglobulins …
Matched Categories: … Immune Sera and Immunoglobulins …
Calcium citrate
Calcium citrate is a salt typically used as a source of calcium in a variety of over the counter supplements.
Approved
Investigational
Matched Iupac: … tricalcium bis(2-hydroxypropane-1,2,3-tricarboxylate) …
Matched Description: … Calcium citrate is a salt typically used as a source of calcium in a variety of over the counter supplements …
Matched Mixtures name: … Mid-life Magnacal 2 ... Calcium Magnesium 2:1 Tablets With Vitamin D ... Calcium and Mag-potass and Zinc Cap …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Diet, Food, and Nutrition ... Alimentary Tract and Metabolism ... ascorbic acid (vit C) and calcium ... Calcium-Regulating Hormones and Agents …
Matched Description: … Calcium citrate is a salt typically used as a source of calcium in a variety of over the counter supplements …
Matched Mixtures name: … Mid-life Magnacal 2 ... Calcium Magnesium 2:1 Tablets With Vitamin D ... Calcium and Mag-potass and Zinc Cap …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Diet, Food, and Nutrition ... Alimentary Tract and Metabolism ... ascorbic acid (vit C) and calcium ... Calcium-Regulating Hormones and Agents …
Berdazimer
Berdazimer is a polymeric substance consisting of a polysiloxane backbone (Si-O-Si bonds) with covalently bound N-diazeniumdiolate nitric oxide (NO) donors. It releases NO through exposure to proton donors like water, which will degrade the N-diazeniumdiolate entity. Berdazimer was previously investigated as a potential treatment for molluscum contagiosum, a viral cutaneous...
Approved
Matched Synonyms: … Silsesquioxanes, 3-(2-hydroxy-1-methyl-2-nitrosohydrazinyl)propyl 3-(methylamino)propyl, polymers with …
Matched Description: … This decision is based on positive results demonstrated in 2 Phase 3 trials, B-SIMPLE 4 and B-SIMPLE ... 2, where reduced lesion counts were observed with once-a-day uses of berdazimer. ... of adult and pediatric molluscum contagiosum, and it is the first drug to be approved for this condition …
Matched Description: … This decision is based on positive results demonstrated in 2 Phase 3 trials, B-SIMPLE 4 and B-SIMPLE ... 2, where reduced lesion counts were observed with once-a-day uses of berdazimer. ... of adult and pediatric molluscum contagiosum, and it is the first drug to be approved for this condition …
Carvedilol
Carvedilol is a racemic mixture where the S(-) enantiomer is both a beta and alpha-1 adrenoceptor blocker, and the R(+) enantiomer is an alpha-1 adrenoceptor blocker.[L7889,L7892] It is currently used to treat heart failure, left ventricular dysfunction, and hypertension.[L7889,L7892] The dual action of carvedilol is advantageous in combination therapies as...
Approved
Investigational
Matched Synonyms: … (+-)-1-(Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol …
Matched Iupac: … 1-(9H-carbazol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino}propan-2-ol …
Matched Description: … Carvedilol is a racemic mixture where the S(-) enantiomer is both a beta and alpha-1 adrenoceptor blocker ... ,L7892] The dual action of carvedilol is advantageous in combination therapies as moderate doses of 2 ... , and the R(+) enantiomer is an alpha-1 adrenoceptor blocker. …
Matched Salts cas: … 610309-89-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring ... Compounds used in a research, industrial, or household setting ... carvedilol and ivabradine ... Alpha and Beta Blocking Agents …
Matched Iupac: … 1-(9H-carbazol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino}propan-2-ol …
Matched Description: … Carvedilol is a racemic mixture where the S(-) enantiomer is both a beta and alpha-1 adrenoceptor blocker ... ,L7892] The dual action of carvedilol is advantageous in combination therapies as moderate doses of 2 ... , and the R(+) enantiomer is an alpha-1 adrenoceptor blocker. …
Matched Salts cas: … 610309-89-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring ... Compounds used in a research, industrial, or household setting ... carvedilol and ivabradine ... Alpha and Beta Blocking Agents …
Homosalate
Homosalate is an organic compound that belongs to salicylates. It is an ester formed from salicylic acid and 3,3,5-trimethylcyclohexanol, a derivative of cyclohexanol. Salicylates prevent direct skin exposure to the sun’s harmful rays by absorbing ultraviolet (UV) light. Homosalate specifically absorbs short-wave UVB rays, which are associated with DNA damage...
Approved
Investigational
Matched Synonyms: … 3,3,5-Trimethylcyclohexyl 2-hydroxybenzoate …
Matched Iupac: … 3,3,5-trimethylcyclohexyl 2-hydroxybenzoate …
Matched Description: … It is an ester formed from salicylic acid and 3,3,5-trimethylcyclohexanol, a derivative of cyclohexanol ... It is a common ingredient in many commercially available sunscreens. ... Homosalate specifically absorbs short-wave UVB rays, which are associated with DNA damage and increased …
Matched Mixtures name: … Destination Brands International BROAD SPECTRUM SPF 50 Sunscreen ... 2 in 1 Sunscreen and Gradual Self-Tanner ... Hope In A Jar SPF 25 …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Iupac: … 3,3,5-trimethylcyclohexyl 2-hydroxybenzoate …
Matched Description: … It is an ester formed from salicylic acid and 3,3,5-trimethylcyclohexanol, a derivative of cyclohexanol ... It is a common ingredient in many commercially available sunscreens. ... Homosalate specifically absorbs short-wave UVB rays, which are associated with DNA damage and increased …
Matched Mixtures name: … Destination Brands International BROAD SPECTRUM SPF 50 Sunscreen ... 2 in 1 Sunscreen and Gradual Self-Tanner ... Hope In A Jar SPF 25 …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Suprofen
An ibuprofen-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. It is no longer approved for use in the United States.
Approved
Withdrawn
Matched Synonyms: … 2-(4-(2-Thenoyl)phenyl)propionsäure ... (±)-2-(p-(2-thenoyl)phenyl)propionic acid ... 2-[4-(Thiophene-2-carbonyl)-phenyl]-propionic acid …
Matched Iupac: … 2-[4-(thiophene-2-carbonyl)phenyl]propanoic acid …
Matched Description: … It is no longer approved for use in the United States. ... An ibuprofen-type anti-inflammatory analgesic and antipyretic. ... It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. …
Matched Categories: … Non COX-2 selective NSAIDS ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Iupac: … 2-[4-(thiophene-2-carbonyl)phenyl]propanoic acid …
Matched Description: … It is no longer approved for use in the United States. ... An ibuprofen-type anti-inflammatory analgesic and antipyretic. ... It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. …
Matched Categories: … Non COX-2 selective NSAIDS ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Dexlansoprazole
Dexlansoprazole is a new-generation proton pump inhibitor (PPI) used for the management of symptoms associated with gastroesophageal reflux disease (GERD) and erosive esophagitis. Dexlansoprazole is the R-enantiomer of DB00448, which is composed of a racemic mixture of the R- and S-enantiomers. Compared to the older generation of PPIs (which includes...
Approved
Investigational
Matched Synonyms: … (+)-2-((R)-((3-METHYL-4-(2,2,2-TRIFLUOROETHOXY)PYRIDIN-2-YL)METHYL)SULFINYL)-1H-BENZIMIDAZOLE ... 1H-BENZIMIDAZOLE, 2-((R)-((3-METHYL-4-(2,2,2-TRIFLUOROETHOXY)-2-PYRIDINYL)METHYL)SULFINYL)- ... 2-((R)-((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazole …
Matched Iupac: … 2-[(R)-[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methanesulfinyl]-1H-1,3-benzodiazole …
Matched Description: … Dexlansoprazole is the R-enantiomer of [DB00448], which is composed of a racemic mixture of the R- and ... ] dexlansoprazole has a unique pharmacokinetic profile due to its delayed-release and dual-delivery release ... Dexlansoprazole is a new-generation proton pump inhibitor (PPI) used for the management of symptoms associated …
Matched Categories: … Alimentary Tract and Metabolism ... 2-Pyridinylmethylsulfinylbenzimidazoles ... Heterocyclic Compounds, 2-Ring ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Iupac: … 2-[(R)-[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methanesulfinyl]-1H-1,3-benzodiazole …
Matched Description: … Dexlansoprazole is the R-enantiomer of [DB00448], which is composed of a racemic mixture of the R- and ... ] dexlansoprazole has a unique pharmacokinetic profile due to its delayed-release and dual-delivery release ... Dexlansoprazole is a new-generation proton pump inhibitor (PPI) used for the management of symptoms associated …
Matched Categories: … Alimentary Tract and Metabolism ... 2-Pyridinylmethylsulfinylbenzimidazoles ... Heterocyclic Compounds, 2-Ring ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Sulfinpyrazone
A uricosuric drug that is used to reduce the serum urate levels in gout therapy. It lacks anti-inflammatory, analgesic, and diuretic properties.
Approved
Matched Synonyms: … 1,2-Diphenyl-3,5-dioxo-4-(2-phenylsulfinylethyl)pyrazolidine ... 1,2-Diphenyl-4-(2'-phenylsulfinethyl)-3,5-pyrazolidinedione ... 4-(2-Benzenesulfinylethyl)-1,2-diphenylpyrazolidine-3,5-dione …
Matched Iupac: … 4-[2-(benzenesulfinyl)ethyl]-1,2-diphenylpyrazolidine-3,5-dione …
Matched Description: … It lacks anti-inflammatory, analgesic, and diuretic properties. ... A uricosuric drug that is used to reduce the serum urate levels in gout therapy. …
Matched Iupac: … 4-[2-(benzenesulfinyl)ethyl]-1,2-diphenylpyrazolidine-3,5-dione …
Matched Description: … It lacks anti-inflammatory, analgesic, and diuretic properties. ... A uricosuric drug that is used to reduce the serum urate levels in gout therapy. …
Codeine
The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities. Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease...
Approved
Illicit
Matched Synonyms: … morphine 3-methyl ether ... morphine-3-methyl ether ... 7,8-didehydro-4,5α-epoxy-3-methoxy-17-methylmorphinan-6α-ol …
Matched Description: … Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease ... The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for ... [A175096] Codeine is utilized as a central analgesic, sedative, hypnotic, antinociceptive, and antiperistaltic …
Matched Mixtures name: … A-FERİN 300 MG/2 MG/10 MG KAPSÜL, 20 ADET ... A-FERİN 300 MG/2 MG/10 MG KAPSÜL, 30 ADET ... A-FERİN 300 MG/2 MG/10 MG KAPSÜL, 500 ADET …
Matched Categories: … Cough and Cold Preparations ... codeine and ibuprofen ... codeine and paracetamol ... Opium Alkaloids and Derivatives ... codeine and acetylsalicylic acid …
Matched Description: … Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease ... The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for ... [A175096] Codeine is utilized as a central analgesic, sedative, hypnotic, antinociceptive, and antiperistaltic …
Matched Mixtures name: … A-FERİN 300 MG/2 MG/10 MG KAPSÜL, 20 ADET ... A-FERİN 300 MG/2 MG/10 MG KAPSÜL, 30 ADET ... A-FERİN 300 MG/2 MG/10 MG KAPSÜL, 500 ADET …
Matched Categories: … Cough and Cold Preparations ... codeine and ibuprofen ... codeine and paracetamol ... Opium Alkaloids and Derivatives ... codeine and acetylsalicylic acid …
Carbocisteine
Dyspnea and cough are common symptoms of chronic obstructive pulmonary disease (COPD) and other respiratory conditions characterized by increased mucus production. Individuals with COPD have a greater risk of pulmonary infection due to the growth and accumulation of viruses and bacteria in thick bronchial mucus. Carbocisteine is a mucolytic drug...
Approved
Investigational
Matched Synonyms: … (L)-2-Amino-3-(carboxymethylthio)propionic acid ... L-3-((carboxymethyl)thio)alanine …
Matched Iupac: … (2R)-2-amino-3-[(carboxymethyl)sulfanyl]propanoic acid …
Matched Description: … Individuals with COPD have a greater risk of pulmonary infection due to the growth and accumulation of ... Carbocisteine is a mucolytic drug that alleviates respiratory symptoms and infections by reducing the ... [A230993] Carbocisteine is currently not FDA or Health Canada approved, but is approved for use in Asia …
Matched Categories: … Cough and Cold Preparations ... Amino Acids, Peptides, and Proteins …
Matched Products: … RHINATHIOL 2% CHILDREN SYRUP ... PAXJARABE PARA LA TOS 2% NIÑOS ... PAX JARABE PARA LA TOS (SIN AZUCAR) 2% NIÑOS …
Matched Iupac: … (2R)-2-amino-3-[(carboxymethyl)sulfanyl]propanoic acid …
Matched Description: … Individuals with COPD have a greater risk of pulmonary infection due to the growth and accumulation of ... Carbocisteine is a mucolytic drug that alleviates respiratory symptoms and infections by reducing the ... [A230993] Carbocisteine is currently not FDA or Health Canada approved, but is approved for use in Asia …
Matched Categories: … Cough and Cold Preparations ... Amino Acids, Peptides, and Proteins …
Matched Products: … RHINATHIOL 2% CHILDREN SYRUP ... PAXJARABE PARA LA TOS 2% NIÑOS ... PAX JARABE PARA LA TOS (SIN AZUCAR) 2% NIÑOS …
Allopurinol
Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially around joints . This disease has been well-documented in historical medical records and appears in the biographies of several prominent, historically recognized individuals .
Allopurinol is a xanthine oxidase enzyme inhibitor that...
Approved
Matched Description: … It was initially approved by the FDA in 1966 [L5674] and is now formulated by several manufacturers [ ... Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially ... Allopurinol is a xanthine oxidase enzyme inhibitor that is considered to be one of the most effective …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Olipudase alfa
Olipudase alfa is recombinant human acid sphingomyelinase. It is the first and only enzyme replacement therapy in the world for the treatment of Acid Sphingomyelinase Deficiency (ASMD), also known as Niemann–Pick disease. ASMD is a rare lysosomal storage disease caused by mutations in the SMPD1 gene, leading to a deficiency...
Approved
Investigational
Matched Description: … [A251590] It was later approved by the European Commission on June 28, 2022 [L42740] and by the FDA on ... [L42740] ASMD is a rare lysosomal storage disease caused by mutations in the SMPD1 gene, leading to a ... [A251590] It is the first and only enzyme replacement therapy in the world for the treatment of Acid …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Ingenol mebutate
Ingenol mebutate was approved by the FDA in January 2012, and it is marketed under the name Picato®. Picato gel is indicated for the topical treatment of actinic keratosis. Before approval, ingenol mebutate was called PEP005 as an investigational drug. PEP005 is a selective small molecule activator of protein kinase...
Approved
Matched Synonyms: … 3-Angeloylingenol ... 3-Ingenyl angelate ... Ingenol 3-angelate …
Matched Iupac: … methylbut-2-enoate ... hydroxymethyl)-3,11,11,14-tetramethyl-15-oxotetracyclo[7.5.1.0^{1,5}.0^{10,12}]pentadeca-2,7-dien-4-yl (2Z)-2- …
Matched Description: … Ingenol mebutate was approved by the FDA in January 2012, and it is marketed under the name Picato®. ... warts and cancer. ... peplus, whose sap has been used as a traditional medicine for the treatment of skin conditions including …
Matched Categories: … Skin and Mucous Membrane Agents …
Matched Iupac: … methylbut-2-enoate ... hydroxymethyl)-3,11,11,14-tetramethyl-15-oxotetracyclo[7.5.1.0^{1,5}.0^{10,12}]pentadeca-2,7-dien-4-yl (2Z)-2- …
Matched Description: … Ingenol mebutate was approved by the FDA in January 2012, and it is marketed under the name Picato®. ... warts and cancer. ... peplus, whose sap has been used as a traditional medicine for the treatment of skin conditions including …
Matched Categories: … Skin and Mucous Membrane Agents …
Tipiracil
Tipiracil is a thymidine phosphorylase inhibitor. It is used in combination with trifluridine, in a ratio of 1:0.5, to form TAS-102. The main function of Tipiracil in TAS-102 is to increase trifluridine bioavailability by inhibiting its catabolism. TAS-102 is indicated for the treatment of metastatic colorectal cancer which has been...
Approved
Investigational
Matched Synonyms: … 5-chloro-6-(2-iminopyrrolidin-1-yl)methyl-2,4(1H,3H)-pyrimidinedione ... 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1H-pyrimidine-2,4-dione …
Matched Iupac: … 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … Tipiracil is a thymidine phosphorylase inhibitor. ... metastatic colorectal cancer which has been previously treated with fluoropyrimidine-, oxaliplatin- and ... It is used in combination with trifluridine, in a ratio of 1:0.5, to form TAS-102. …
Matched Categories: … MATE 1 Substrates with a Narrow Therapeutic Index ... OCT2 Substrates with a Narrow Therapeutic Index …
Matched Iupac: … 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … Tipiracil is a thymidine phosphorylase inhibitor. ... metastatic colorectal cancer which has been previously treated with fluoropyrimidine-, oxaliplatin- and ... It is used in combination with trifluridine, in a ratio of 1:0.5, to form TAS-102. …
Matched Categories: … MATE 1 Substrates with a Narrow Therapeutic Index ... OCT2 Substrates with a Narrow Therapeutic Index …
Phenobarbital
A barbituric acid derivative that acts as a nonselective central nervous system depressant. It promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
Approved
Investigational
Matched Description: … A barbituric acid derivative that acts as a nonselective central nervous system depressant. ... It promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents …
Matched Mixtures name: … Phenaphen No 3 Cap ... Phenaphen No 2 Cap ... Phenaphen No.3 Cap …
Matched Categories: … Barbiturates and Derivatives ... Hypnotics and Sedatives ... Phenobarbital and similars ... Metabolic Side Effects of Drugs and Substances ... P-glycoprotein substrates with a Narrow Therapeutic Index …
Matched Mixtures name: … Phenaphen No 3 Cap ... Phenaphen No 2 Cap ... Phenaphen No.3 Cap …
Matched Categories: … Barbiturates and Derivatives ... Hypnotics and Sedatives ... Phenobarbital and similars ... Metabolic Side Effects of Drugs and Substances ... P-glycoprotein substrates with a Narrow Therapeutic Index …
Chlormezanone
A non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.
Approved
Investigational
Withdrawn
Matched Synonyms: … 2-(p-chlorphenyl)-3-methyl-1,3-perhydrothiazin-4-on-1,1-dioxide ... 2-(p-chlorophenyl)tetrahydro-3-methyl-4H-1,3-thiazin-4-one 1,1-dioxide …
Matched Iupac: … 2-(4-chlorophenyl)-3-methyl-1lambda6,3-thiazinane-1,1,4-trione …
Matched Description: … A non-benzodiazepine that is used in the management of anxiety. …
Matched Categories: … Oxazol, Thiazine, and Triazine Derivatives …
Matched Iupac: … 2-(4-chlorophenyl)-3-methyl-1lambda6,3-thiazinane-1,1,4-trione …
Matched Description: … A non-benzodiazepine that is used in the management of anxiety. …
Matched Categories: … Oxazol, Thiazine, and Triazine Derivatives …
Estriol
A hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3-beta, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen. During pregnancy, large amount of estriol is produced by the placenta. Isomers with inversion of the hydroxyl group or groups are called epiestriol. Though estriol is...
Approved
Investigational
Vet approved
Matched Iupac: … (1R,2R,3aS,3bR,9bS,11aS)-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene …
Matched Description: … It has also been approved and marketed throughout Europe and Asia for approximately 40 years for the ... A hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3-beta, 16-alpha, and ... Estriol is a major urinary estrogen. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Natural and Semisynthetic Estrogens, Plain ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … It has also been approved and marketed throughout Europe and Asia for approximately 40 years for the ... A hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3-beta, 16-alpha, and ... Estriol is a major urinary estrogen. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Natural and Semisynthetic Estrogens, Plain ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Entrectinib
Entrectinib is a tropomyosin receptor tyrosine kinase (TRK) TRKA, TRKB, TRKC, proto-oncogene tyrosine-protein kinase ROS1, and anaplastic lymphoma kinase (ALK) inhibitor. It was approved by the FDA in August 2019 for use in the treatment of ROS1-positive metastatic non-small cell lung cancer and NTRK gene fusion positive solid tumors. Entrectinib's...
Approved
Investigational
Matched Synonyms: … N-[5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl]-4-(4-methylpiperazin-1-yl)-2-(oxan-4-ylamino)benzamide …
Matched Iupac: … N-{5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl}-4-(4-methylpiperazin-1-yl)-2-[(oxan-4-yl)amino]benzamide …
Matched Description: … [L8207] Entrectinib's approved use is meant as a last line of therapy due to its accelerated approval ... ] due to a wider range of targets. ... kinase ROS1, and anaplastic lymphoma kinase (ALK) inhibitor. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Iupac: … N-{5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl}-4-(4-methylpiperazin-1-yl)-2-[(oxan-4-yl)amino]benzamide …
Matched Description: … [L8207] Entrectinib's approved use is meant as a last line of therapy due to its accelerated approval ... ] due to a wider range of targets. ... kinase ROS1, and anaplastic lymphoma kinase (ALK) inhibitor. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Bumetanide
Bumetanide is a sulfamyl diuretic.
Approved
Matched Synonyms: … 3-butylamino-4-(phenoxy)-5-sulfamoylbenzoic acid ... 3-butylamino-4-phenoxy-5-sulfamoyl-benzoic acid ... 3-butylamino-4-phenoxy-5-sulfamoylbenzoic acid …
Matched Iupac: … 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid …
Matched Description: … Bumetanide is a sulfamyl diuretic. …
Matched Categories: … bumetanide and potassium ... Genito Urinary System and Sex Hormones ... bumetanide and potassium-sparing agents ... Gynecological Antiinfectives and Antiseptics ... High-Ceiling Diuretics and Potassium-Sparing Agents …
Matched Products: … Burinex 2 mg - Ampullen …
Matched Iupac: … 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid …
Matched Description: … Bumetanide is a sulfamyl diuretic. …
Matched Categories: … bumetanide and potassium ... Genito Urinary System and Sex Hormones ... bumetanide and potassium-sparing agents ... Gynecological Antiinfectives and Antiseptics ... High-Ceiling Diuretics and Potassium-Sparing Agents …
Matched Products: … Burinex 2 mg - Ampullen …
Displaying drugs 701 - 725 of 5178 in total