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Displaying drugs 51 - 75 of 6669 in total
Octinoxate is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize DNA photodamage. It was originally developed in 1950's as an organic UV-B filter that absorbs UV-B rays from sun. It is often combined with nanoparticles or other water-resistant liposomes in formulations to increase...
Approved
Investigational
Matched Iupac: … 2-ethylhexyl (2E)-3-(4-methoxyphenyl)prop-2-enoate …
Matched Mixtures name: … Soleil Ambre SPF 5 ... Brume Solaire SPF 5 ... SPF 4
Matched Products: … Revitalizing Concealer - Stk 5% ... Revitalizing Liquid Make-UP - 5% ... Lbel Replenishing Foundation SPF 14 (medium 5) - Brown …
Repotrectinib is a next-generation tyrosine kinase inhibitor (TKI) specifically designed to address resistance in the treatment of non-small cell lung cancer (NSCLC), specifically due to mutations in the ROS1 gene. ROS1 mutations are one of the defined oncogenic drives of NSCLC, and the solvent-front mutation ROS1 G2032R is responsible for...
Approved
Investigational
Matched Synonyms: … (3R,6S,)-45-FLUORO-3,6-DIMETHYL-5-OXA-2,8-DIAZA-1(5,3)-PYRAZOLO(1,5-A)PYRIMIDINA-4(1,2)-BENZENANONAPHAN ... Fluoro-7,13-Dimethyl-6,7,13,14-Tetrahydro-1,15-Ethenopyrazolo[4,3-F][1,4,8,10]Benzoxatriazacyclotridecin-4( ... 1,15-ETHENO-1H-PYRAZOLO(4,3-F)(1,4,8,10)BENZOXATRIAZACYCLOTRIDECIN-4(5H)-ONE, 11-FLUORO-6,7,13,14-TETRAHYDRO …
Sapropterin (tetrahydrobiopterin or BH4) is a cofactor in the synthesis of nitric oxide. It is also essential in the conversion of phenylalanine to tyrosine by the enzyme phenylalanine-4-hydroxylase; the conversion of tyrosine to L-dopa by the enzyme tyrosine hydroxylase; and conversion of tryptophan to 5-hydroxytryptophan via tryptophan hydroxylase.
Approved
Investigational
Matched Synonyms: … 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)-pteridinone ... (−)-(6R)-2-amino-6-((1R,2S)-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4(3H)-pteridinone …
Matched Iupac: … (6R)-2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-3,4,5,6,7,8-hexahydropteridin-4-one …
Matched Description: … conversion of tyrosine to L-dopa by the enzyme tyrosine hydroxylase; and conversion of tryptophan to 5- ... It is also essential in the conversion of phenylalanine to tyrosine by the enzyme phenylalanine-4-hydroxylase …
Matched Salts cas: … 69056-38-8
A semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division,...
Approved
Matched Synonyms: … 9-((4,6-O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl ... 4-demethylepipodophyllotoxin β-D-ethylideneglucoside ... )furo(3',4'':6,7)naptho-(2,3-d)-1,3-dioxol-6(5aH)-one …
Matched Iupac: … -{[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-hexahydro-2H-pyrano[3,2-d][1,3]dioxin-6-yl]oxy}-10-(4- ... hydroxy-3,5-dimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1,3(7),8-trien- …
Matched Products: … ETOSID 100 MG/ 5 ML ... ETOPOSIDO 100 MG / 5 ML ... ETOPOSIDO EBEWE 100 MG/5 ML. …
Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conversion into the thromboxane-2 and prostaglandin-2 families.
Approved
Nutraceutical
Matched Mixtures name: … TODAVİT IM/IV ENJEKSİYONLUK/İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 4 ADET …
Matched Products: … FOLSET 5 MG TABLET ... FOLSET 5 MG TABLET, 50 ADET ... FOLAS 5 MG TABLET, 50 ADET …
Perfluorohexyloctane is a semifluorinated alkane that contains six perfluorinated carbon atoms and eight hydrogenated carbon atoms. It is an inert, slightly amphiphilic compound. Because it is a completely non-aqueous liquid, microbial growth is not possible; therefore, its drug products do not need to be combined with any preservative.[A259746, A259751] Perfluorohexyloctane...
Approved
Lorcaserin (previously APD-356), a highly selective 5HT2C receptor agonist, is used for the treatment of obesity. It has been shown to reduce body weight and food intake in animal models of obesity, and it is thought that targeting the 5HT2C receptor may alter body weight by regulating satiety. Lorcaserin is...
Approved
Withdrawn
Matched Iupac: … (1R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine …
Matched Salts cas: … 846589-98-8 ... 856681-05-5
Matched Categories: … Serotonin 5-HT2 Receptor Agonists ... Serotonin 5-HT2C Receptor Agonists …
Acetaminophen (paracetamol), also commonly known as Tylenol, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). It is also used for its antipyretic effects, helping to reduce fever. This drug was initially approved by the U.S. FDA...
Approved
Matched Synonyms: … 4-acetamidophenol ... 4-(Acetylamino)phenol ... 4'-hydroxyacetanilide …
Matched Iupac: … N-(4-hydroxyphenyl)acetamide …
Matched Mixtures name: … Exdol-8 ... Atasol 8 ... Triatec-8
Matched Products: … VOLPAN TABLET, 4 ADET ... VOLPAN KOMPOZE TABLET, 4 ADET ... Tylenol 8 HR …
An alkaloid found in the root of Rauwolfia serpentina, among other plant sources. It is a class Ia antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac action potentials. Ajmaline produces potent sodium channel blocking effects and a very short half-life which makes it a very...
Approved
Experimental
Matched Synonyms: … (5aR,6S,8S,10S,11S,11aS,12aR,13R)-5-methyl-5a,6,8,9,10,11,11a,12-octahydro-5H-6,10:11,12a-dimethanoindolo …
Matched Iupac: … (1R,9R,10S,12R,13S,14R,16S,18R)-13-ethyl-8-methyl-8,15-diazahexacyclo[14.2.1.0^{1,9}.0^{2,7}.0^{10,15 …
Matched Products: … Gilurytmal 5 mg/ml Injektionslösung und Konzentrat zur Herstellung einer Infusionslösung …
Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states including autoimmune disorders. Betamethasone has potent glucocorticoid activity and negligible mineralocorticoid activity.
Approved
Vet approved
Matched Salts cas: … 5593-20-4 ... 151-73-5 ... 2152-44-5
Matched Mixtures name: … เดอมิกซ์-4 ... Betamethasone Dipropionate 0.05% / Niacinamide 4% ... BETNOVATE-C % 0,1 + % 3 KREM, 5 GR …
Matched Products: … XORSONE 1:8 cream ... BETAMETASONA 8 MG/ 2 ML ... NOVOVATE KREM, 5 G …
Povidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It contains from 9.0% to 12.0% available iodine, calculated on a dry basis. This unique complex was discovered in 1955 at the Industrial Toxicology Laboratories in Philadelphia by H. A. Shelanski and M. V. Shelanski. During in...
Approved
Matched Mixtures name: … Pro-C-Dure 4 Kit …
Matched Products: … Betadine Shampoo for Dry Hair 4% ... Povidone Iodine Swabsticks 4 Triple ... Viodin 5%w/w Ointment …
A purine base and a fundamental unit of adenine nucleotides.
Approved
Nutraceutical
Matched International brands: … Leuco-4
Matched Mixtures name: … HEPATAMINE %8 500 ML(SETLI) ... HEPATAMINE %8 500 ML(SETSIZ) ... Blood Bag System with Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) AND OPTISOL (AS-5) …
Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin) is the 5-formyl derivative of tetrahydrofolic acid, a necessary co-factor in the body. Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the...
Approved
Matched Synonyms: … 5-Formyltetrahydrofolate ... 5-formyltetrahydrofolic acid ... 5-Formyl-5,6,7,8-tetrahydrofolic acid …
Matched Iupac: … (2S)-2-[(4-{[(2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}phenyl)formamido …
Matched Description: … Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin) is the 5-formyl derivative of ... anemias due to folic acid deficiency when oral therapy is not feasible and for use in combination with 5- …
Matched Salts cas: … 1492-18-8 ... 163254-40-8
Matched Products: … KALSIYUM FOLINAT EBEWE 50 MG/5 ML ENJEKTABL ÇÖZELTİ İÇEREN AMPUL, 5 ADET ... RESCUVOLIN 5 MG/ML 100 MG ... RESCUVOLIN 5 MG/ML 200 MG …
Approved
Experimental
HIV/AIDS remains an area of concern despite the introduction of numerous successful therapies, mainly due to the emergence of multidrug resistance and patient difficulty in adhering to treatment regimens.[A244170, A244175] Lenacapavir is a first-in-class capsid inhibitor that demonstrates picomolar HIV-1 inhibition as a monotherapy in vitro, little to no cross-resistance...
Approved
Investigational
Matched Iupac: … N-[(1S)-1-{3-[4-chloro-3-methanesulfonamido-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl]-6-(3-methanesulfonyl ... difluorophenyl)ethyl]-2-[(2S,4R)-5,5-difluoro-9-(trifluoromethyl)-7,8-diazatricyclo[4.3.0.0^{2,4}]nona-1(6),8- …
Matched Salts cas: … 2283356-12-5
Duchenne muscular dystrophy (DMD) is an X-linked recessive allelic disorder characterized by a lack of functional dystrophin protein, which leads to progressive impairment of ambulatory, pulmonary, and cardiac function and is invariably fatal. A related, albeit a less severe, form of muscular dystrophy known as Becker muscular dystrophy (BMD) is...
Approved
Investigational
Ephedrine was first described in western literature in 1888, as a naturally occurring component of the ephedra plant, along with pseudoephedrine. Ephedrine acts as both a direct and indirect sympathomimetic. It is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of norepinephrine from sympathetic neurons,...
Approved
Matched Salts cas: … 134-72-5
Matched Mixtures name: … BROKSIN 6.66 MG/5 ML+100 MG/5 ML SURUP, 150 ML …
Matched Products: … Ephedrine HCl 8 mg …
Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in 1996. It is considered to be a third generation alpha-2 aadrenergic receptor agonist, since it displays preferential binding at alpha-2 adrenoceptors over alpha-1 receptors. Brimonidine displays a higher selectivity toward the alpha-2 adrenergic receptors than clonidine or...
Approved
Matched Synonyms: … 5-Bromo-6-(2-imidazolin-2-ylamino)quinoxaline …
Matched Iupac: … 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine …
Matched Salts cas: … 70359-46-5
Matched Mixtures name: … Brimonidine Tartrate 0.25% / Ivermectin 1% / Metronidazole 1% / Niacinamide 4% ... BRİMO-TİM 2 MG+5 MG/ML STERİL GÖZ DAMLASI, ÇÖZELTİ, 5 ML ... RIMOSOPT GÖZ DAMLASI, 5 ML …
Matched Products: … Brimonidine Tartrate 0.25% / Potassium Azeloyl Diglycinate 8% ... RİMONAL % 0.2 GÖZ DAMLASI, 5 ML ... BRIMOGUT % 0.2 GÖZ DAMLASI , 5 ML …
Siltuximab is a chimeric (human-mouse) monoclonal immunoglobulin G1-kappa antibody produced in a Chinese hamster ovary (CHO) cell line by recombinant DNA technology. Siltuximab prevents the binding of IL-6 to soluble and membrane-bound IL-6 receptors by forming high affinity complexes with human interleukin-6 (IL-6). Its use is indicated for the treatment...
Approved
Investigational
Matched Description: … (HHV-8) negative. ... Castleman's disease (MCD) who are human immunodeficiency virus (HIV) negative and human herpesvirus-8
Ketotifen is a benzocycloheptathiophene derivative with potent antihistaminic and mast cell stabilizing properties. It has a similar structure to some other first-generation antihistamines such as cyproheptadine and azatadine. Ketotifen was first developed in Switzerland in 1970 by Sandoz Pharmaceuticals and was initially marketed for the treatment of anaphylaxis. In the...
Approved
Matched Iupac: … 2-(1-methylpiperidin-4-ylidene)-6-thiatricyclo[8.4.0.0^{3,7}]tetradeca-1(14),3(7),4,10,12-pentaen-8-one …
Matched Salts cas: … 34580-14-8
Matched Products: … KETEN SYRUP 1 mg/5 ml ... ASMAFEN SYRUP 1 mg/5 ml ... ASTAFEN 1 MG/5 ML ŞURUP …
Tilbroquinol was approved in France, Morocco, and Saudi Arabia but it has been withdrawn in France and Saudi Arabia markets mainly due to its hepatotoxicity risk outweighing the drug benefit . In Morocco, the drug has been limited to use in the treatment of intestinal amoebiasis.
Approved
Matched Iupac: … 7-bromo-5-methylquinolin-8-ol …
Chromium Cr-51 is an isotope of chromium that has been used as a radioactive label for decades. It is used as a diagnostic radiopharmaceutical agent in nephrology to determine glomerular filtration rate,[A249765,A249770] and in hematology to determine red blood cell volume or mass, study the red blood cell survival time...
Approved
Matched Salts cas: … 27849-89-4
Levomefolic acid (INN) is the metabolite of folic acid (Vitamin B9) and it is a predominant active form of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma . It is transported across the membranes including the blood-brain barrier into various tissues...
Approved
Investigational
Matched Synonyms: … N-[4-[[[(6S)-2-Amino-3,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-L-glutamic ... L-5-MTHF ... (6S)-5-MTHF …
Matched Iupac: … (2S)-2-{[4-({[(6S)-2-amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido …
Matched Mixtures name: … Sodium polysulthionate, 5-methyltetrahydrofolate ... Levomefolate Calcium Pyridoxal-5 Phosphate Mecobalamin Algal ... Levomefolate Calcium, Pyridoxal 5-phosphate, Methylcobalamin and Schizochytrium DHA Oil …
Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays...
Approved
Investigational
Nutraceutical
Vet approved
Matched Iupac: … 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium …
Matched Salts cas: … 532-43-4 ... 59-43-8 ... 67-03-8
Matched Mixtures name: … HEPATAMINE %8 500 ML(SETLI) ... HEPATAMINE %8 500 ML(SETSIZ) ... Mvc 9+4 Inj …
Matched Products: … VI-PLEX B1 250 MG/2 ML AMPUL, 5 ADET …
An anthracenedione-derived antineoplastic agent.
Approved
Investigational
Matched Products: … MİTOXANTRON EBEWE 10 MG/5 ML IV İNFÜZYON İÇİN KONSANTRE ÇÖZELTİ İÇEREN FLAKON, 1 ADET …
Displaying drugs 51 - 75 of 6669 in total