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Displaying drugs 51 - 75 of 12032 in total
Sotorasib, also known as AMG-510, is an acrylamide-derived KRAS inhibitor developed by Amgen.[A187547,A187556] It is indicated in the treatment of adult patients with KRAS G12C mutant non-small cell lung cancer. This mutation makes up >50% of all KRAS mutations. Mutant KRAS discovered in 1982 but was not considered a druggable...
Approved
Investigational
Matched Synonyms: … Kras G12C inhibitor 9 ... 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-(1M)-1-[4-methyl-2-(propan-2-yl)pyridin-3-yl]-4-[(2S)-2- methyl ... -4-(prop-2-enoyl)piperazin-1-yl]pyrido[2,3-d]pyrimidin-2(1H)-one …
Matched Iupac: … 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(propan-2-yl)pyridin-3-yl]-4-[(2S)-2-methyl-4-(prop ... -2-enoyl)piperazin-1-yl]-1H,2H-pyrido[2,3-d]pyrimidin-2-one …
Matched Description: … granted FDA approval on May 28, 2021,[L34288] followed by the European Commission's approval on January 10
Thiohexam is a rubber cure accelerator. It is also a known allergen and dermatological sensitizer. Sensitivity to Thiohexam may be identified with a clinical patch test.
Approved
Experimental
Matched Synonyms: … 2-(Cyclohexylaminothio)benzothiazole ... Benzothiazyl-2-cyclohexylsulfenamide ... N-cyclohexyl-2-Benzothiazosulfenamide …
Matched Iupac: … N-(1,3-benzothiazol-2-ylsulfanyl)cyclohexanamine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Glycol salicylate, also known as 2-hydroxyethyl salicylate, is a benzoate ester formed from the condensation of the carboxy group of salicylic acid with one of the hydroxy groups of ethylene glycol. It is found as an active ingredient and topical analgesic in patches used to provide relief for mild to...
Approved
Matched Synonyms: … 2-hydroxyethyl 2-oxidanylbenzoate ... 2-hydroxybenzoic acid 2-hydroxyethyl ester ... 2-hydroxyethyl salicylate …
Matched Iupac: … 2-hydroxyethyl 2-hydroxybenzoate …
An analog of deoxyuridine that inhibits viral DNA synthesis. The drug is used as an antiviral agent.
Approved
Investigational
Matched Synonyms: … (+)-5-Iodo-2'-deoxyuridine ... 2'-Deoxy-5-iodouridine ... 5-iodo-2'-deoxyuridine …
Matched Iupac: … 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Valaciclovir (valacyclovir), also known as Valtrex, is an antiviral drug that has been used to manage and treat various herpes infections for more than 2 decades. It was initially approved by the FDA in 1995 [FDA label] and marketed by GlaxoSmithKline . Valacyclovir is the L-valine ester of aciclovir. It...
Approved
Investigational
Matched Synonyms: … L-Valine, 2-((2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)ethyl ester ... L-Valine ester with 9-((2-hydroxyethoxy)methyl)guanine …
Matched Iupac: … 2-[(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)methoxy]ethyl (2S)-2-amino-3-methylbutanoate …
Matched Description: … is an antiviral drug that has been used to manage and treat various herpes infections for more than 2
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … VIROMED 500 MG FILM TABLET,10 ADET ... VALTREX 500 MG FILM KAPLI TABLET, 10 ADET ... VAXVIRE 500MG FILM KAPLI TABLET, 10 TABLET …
Famotidine is a competitive histamine-2 (H2) receptor antagonist that works to inhibit gastric acid secretion. It is commonly used in gastrointestinal conditions related to acid secretion, such as gastric ulcers and gastroesophageal reflux disease (GERD), in adults and children. Compared to other H2 receptor antagonists, famotidine displays high selectivity towards...
Approved
Matched Synonyms: … 3-(((2-((Diaminomethylene)amino)-4-thiazolyl)methyl)thio)-N(sup 2)-sulfamoylpropionamidine ... N-Sulfamoyl-3-((2-guanidinothiazol-4-yl)methylthio)propionamide ... (1-Amino-3-(((2-((diaminomethylene)amino)-4-thiazolyl)methyl)thio)propylidene)sulfamide …
Matched Iupac: … 3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-yl}methyl)sulfanyl]-N'-sulfamoylpropanimidamide …
Matched Description: … Famotidine is a competitive histamine-2 (H2) receptor antagonist that works to inhibit gastric ... [L11166] Compared to other H2 receptor antagonists, famotidine displays high selectivity towards …
Matched Mixtures name: … ACİDPASS 10 MG/800 MG/165 MG ÇİĞNEME TABLETİ, 2 ADET ... TRIGAST 10 MG/800 MG/165 MG ÇİĞNEME TABLETİ, 6 ADET ... ACİDPASS 10 MG/800 MG/165 MG ÇİĞNEME TABLETİ, 6 ADET …
Matched Products: … FABOS 20 MG/2 ML ENJEKSIYONLUK ÇÖZELTI IÇEREN AMPUL, 2 ADET ... 2 ADET ÇÖZÜCÜ AMPUL ... Famotidine 10 mg …
Atenolol is a cardioselective beta-blocker used in a variety of cardiovascular conditions. Sir James Black, a Scottish pharmacologist, pioneered the use of beta-blockers for the management of angina pectoris in 1958 for which he received the Nobel Prize. Beta-blockers quickly became popular in clinical use and where subsequently investigated for...
Approved
Matched Synonyms: … 2-(p-(2-Hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide ... 1-p-Carbamoylmethylphenoxy-3-isopropylamino-2-propanol ... 4-(2-Hydroxy-3-((1-methylethyl)amino)propoxy)benzeneacetamide …
Matched Iupac: … 2-(4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)acetamide …
Matched Products: … TENORMIN INYECTABLE 5 MG /10 ML. …
Manganese is a transition metal that was first described in the 19th and 20th centuries. It is environmentally abundant, being the fifth most abundant metal and the twelfth most abundant element overall on Earth.[A263657, A263667] Manganese intake primarily occurs through the diet, as it is found at low levels in...
Approved
Nutraceutical
Matched Synonyms: … MANGANESE(2+) ... MANGANESE ION(2+) ... MANGANESE CATION (2+) …
Matched Iupac: … manganese(2+) ion …
Matched Salts cas: … 13446-34-9
Matched Mixtures name: … 24 Multivitamins + Minerals ... For-2 ... TRACUTIL® 10 ML AMPOLLAS …
Nicorandil is an orally efficacious vasodilatory drug and antianginal agent marketed in the UK, Australia, most of Europe, India, Philippines, Japan, South Korea, and Taiwan. It is not an approved drug by FDA. It is a niacinamide derivative that induces vasodilation of arterioles and large coronary arteries by activating potassium...
Approved
Investigational
Matched Synonyms: … 2-Nicotinamidoethyl nitrate ... N-(2-Hydroxyethyl)nicotinamide nitrate ... N-(2-Hydroxyethyl)nicotinamide nitrate (ester) …
Matched Iupac: … 2-[(pyridin-3-yl)formamido]ethyl nitrate …
Matched Products: … Dancor 10 mg - Tabletten ... Nicolan 10 mg - Tabletten ... IKOREL 10 MG TABLET, 30 ADET …
Withdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing tyrosine.
Approved
Withdrawn
Matched Synonyms: … 1-(2-(Benzylcarbamoyl)ethyl)-2-isonicotinoylhydrazine ... 2-(2-(Benzylcarbamoyl)ethyl)hydrazide isonicotinic acid ... 2-(2-(Benzylcarbamyl)ethyl)hydrazide isonicotinic acid …
Pixantrone is an aza-anthracenedione and DNA intercalator which inhibits topoisomerase II. It is similar in structure to anthracyclines such as mitoxantrone, but exerts fewer toxic effects on cardiac tissue. [2] The lower cardio-toxic effects of pixantrone may be explained, in part, by its redox inactivity [3]. Pixantrone does not bind...
Approved
Investigational
Matched Synonyms: … 6,9-bis((2-aminoethyl)amino)benzo(g)isoquinoline-5,10-dione …
Matched Iupac: … 6,9-bis[(2-aminoethyl)amino]-5H,10H-benzo[g]isoquinoline-5,10-dione …
Matched Description: … It will compare pixantrone efficacy to that of gemcitabine. [2] ... structure to anthracyclines such as mitoxantrone, but exerts fewer toxic effects on cardiac tissue. [2] ... It is currently being tested in Phase III trials. [2] Although pixantrone has not yet received FDA …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Gadoteric acid, commonly used in the salt form gadoterate meglumine, is a macrocyclic, ionic gadolinium-based contrast agent (GBCA). It is composed of the organic acid DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) used for its chelating properties, and gadolinium (Gd3+). Gadoterate meglumine has one of the highest thermodynamic stability, apparent stability, and kinetic stability,...
Approved
Matched Synonyms: … [2,2',2'',2'''-(1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrayl-κ4N1,N4,N7,N10)tetraacetato(3−)]gadolinium …
Matched Iupac: … gadolinium(3+) ion 2-[4,7-bis(carboxylatomethyl)-10-(carboxymethyl)-1,4,7,10-tetraazacyclododecan-1-yl …
Matched Description: … imaging (MRI) in the brain (intracranial), spine, and associated tissues in adult and pediatric patients (2
Matched Products: … CLARİSCAN 0.5 MMOL/ML ENJEKSİYONLUK ÇÖZELTİ, 10 ML ... DOTAREM 0,5 MMOL/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 10 ML ... DOTAGRAF 0.5 MMOL/ML ENJEKSIYON IÇIN COZELTI ICEREN FLAKON , 10 ML …
Miconazole is a broad-spectrum azole antifungal with some activity against Gram-positive bacteria as well. It is widely used to treat mucosal yeast infections, including both oral and vaginal infections; although intravenous miconazole is no longer available, a wide variety of suppositories, creams, gels, and tablet-based products are available.[L14021, L14024, L14027,...
Approved
Investigational
Vet approved
Matched Synonyms: … 1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole …
Matched Iupac: … 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole …
Matched Mixtures name: … PERS-MANT %19 + %2 JEL (30 G) ... EKZE-MANT %0,1 + %2 EMÜLSİYON JEL 30 GR …
Matched Products: … ZARIN CREAM 2% ... MICON CREAM 2% ... TINAZOL CREAM 2% …
Approved
Experimental
Matched Synonyms: … 2-(4-Morpholino)thiobenzothiazole ... 2-Benzothiazolylsulfenylmorpholine ... 4-(1,3-benzothiazol-2-ylsulfanyl)morpholine …
Matched Iupac: … 2-(morpholin-4-ylsulfanyl)-1,3-benzothiazole …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Cefdinir, also known as Omnicef, is a semi-synthetic, broad-spectrum antibiotic belonging to the third generation of the cephalosporin class. It has been proven to be effective for the treatment of common bacterial infections in the ear, sinus, throat, lungs, and skin. Cefdinir was approved by the FDA in 1997 to...
Approved
Matched Synonyms: … ]oct-2-ene-2-carboxylic acid ... [4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R,Z)-7-(2-(2-aminothiazol-4-yl)-2-(hydroxyimino)acetamido)-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4.2.0 …
Matched Iupac: … [4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(N-hydroxyimino)acetamido]-3-ethenyl-8-oxo-5-thia-1-azabicyclo …
Matched Mixtures name: … ELUCEF PLUS 500/125 MG EFERVESAN TABLET, 10 ADET ... ELUCEF PLUS 600/125 MG EFERVESAN TABLET, 10 ADET ... FULLCEF PLUS 600/125 MG EFERVESAN TABLET, 10 ADET …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … NUAX 300 MG KAPSÜL,10 ADET ... ENCEF 300 MG KAPSUL, 10 ADET ... CLASEM 300 MG KAPSUL, 10 ADET …
A parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia.
Approved
Matched Synonyms: … 2-(dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate ... 2-phenyl-2-(1-hydroxycyclopentyl)ethanoic acid β-(dimethylamino)ethyl ester ... 2-(dimethylamino)ethyl 1-hydroxy-α-phenylcyclopentaneacetate …
Matched Iupac: … 2-(dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate …
Pioglitazone is an antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications to manage type 2 diabetes mellitus.[L11416,L11419,L11422,L11425] It is administered as a racemic mixture, though there is no pharmacologic difference between the enantiomers and they appear to interconvert in vivo with little consequence. The thiazolidinedione class...
Approved
Investigational
Matched Synonyms: … 5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione ... (±)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione …
Matched Iupac: … 5-({4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl}methyl)-1,3-thiazolidine-2,4-dione …
Matched Description: … antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications to manage type 2 ... bladder cancer) and the availability of safer and more effective alternatives for patients with type 2
Matched Mixtures name: … DUERID 30/2 MG TABLET, 30 ADET ... DUERID 30/2 MG TABLET, 90 ADET …
Cabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree. As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules and induces tumour cell death. Due to its low affinity for the P-glycoprotein (P-gp) efflux pump, cabazitaxel can more readily penetrate the blood–brain barrier compared to...
Approved
Matched Synonyms: … .,10.BETA.-DIMETHOXY-9-OXO-5.BETA.,20-EPOXYTAX-11-ENE-2.ALPHA.,4,13.ALPHA. ... -TRIYL 4-ACETATE 2-BENZOATE 13-((2R,3S)-3-(((TERT-BUTOXY)CARBONYL)AMINO)-2-HYDROXY-3-PHENYLPROPANOATE …
Matched Iupac: … (1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-(acetyloxy)-15-{[(2R,3S)-3-{[(tert-butoxy)carbonyl]amino}-2-hydroxy ... 9,12-dimethoxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^{3,10}.0^{4,7}]heptadec-13-en-2- …
Matched Description: … Cabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree …
Matched Products: … Cabazitaxel EVER Pharma 10 mg/ml Konzentrat zur Herstellung einer Infusionslösung ... Cabazitaxel ratiopharm 10 mg/ml Konzentrat zur Herstellung einer Infusionslösung …
An antibiotic that is produced by Stretomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.
Approved
Investigational
Matched Synonyms: … 2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose ... 2-Deoxy-2-(((methylnitrosoamino)carbonyl)amino)-D-glucopyranose ... N-D-Glucosyl-(2)-N'-nitrosomethylurea …
Riociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for the treatment of patients with inoperable CTEPH (chronic thromboembolic pulmonary hypertension), or persistent/recurrent PH (pulmonary hypertension)...
Approved
Matched Synonyms: … Methyl N-[4,6-Diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-N-methyl-carbaminate …
Matched Iupac: … methyl N-(4,6-diamino-2-{1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl}pyrimidin-5-yl)-N-methylcarbamate …
Matched Products: … Adempas 2 mg film-coated tablet ... PULLMOGUAT® 2 MG TABLETA RECUBIERTA ... ADEMPAS 2 MG FILM KAPLI TABLET , 84 ADET …
Salicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl. Salicylamide is a non-prescription drug with analgesic and antipyretic properties. It has similar medicinal uses to aspirin. Salicylamide is used in combination with both aspirin and caffeine in the over-the-counter pain remedies
Approved
Matched Synonyms: … 2-Carbamoylphenol ... 2-Hydroxybenzamide ... 2-Carboxamidophenol …
Matched Iupac: … 2-hydroxybenzamide …
Matched Categories: … Non COX-2 selective NSAIDS …
The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class, chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking dopamine receptors. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
Approved
Investigational
Vet approved
Matched Synonyms: … 3-(2-chlorophenothiazin-10-yl)-N,N-dimethyl-propan-1-amine ... 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethyl-1-propanamine …
Matched Iupac: … [3-(2-chloro-10H-phenothiazin-10-yl)propyl]dimethylamine …
Matched Products: … ยาฉีดคลอร์โปรมาซีน 50 มิลลิกรัม/2 มิลลิลิตร ... ไบร์-คลอโปร 10 ... LARGACTİL 25MG ENJEKSİYONLUK/İNFÜZYONLUK ÇÖZELTİ İÇEREN AMPUL, 10 ADET …
Everolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian target of rapamycin) inhibitor. It is currently used as an immunosuppressant to prevent rejection of organ transplants. In a similar fashion to other mTOR inhibitors Everolimus' effect is solely on the mTORC1 protein and...
Approved
Matched Synonyms: … 40-O-(2-hydroxyethyl)-rapamycin ... 42-O-(2-Hydroxyethyl)rapamycin …
Matched Iupac: … 1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-(2- ... hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa …
Matched Products: … AFINITOR (2 MG DISPERSIBLE TABLETS) ... EVERONAT 10 ... AFINITOR (10 MG) …
2-Substituted benzimidazole first introduced in 1962. It is active against a variety of nematodes and is the drug of choice for strongyloidiasis. It has CNS side effects and hepatototoxic potential. (From Smith and Reynard, Textbook of Pharmacology, 1992, p919)
Approved
Vet approved
Matched Synonyms: … 4-(2-benzimidazolyl)thiazole ... 2-(thiazol-4-yl)benzimidazole ... 2-(4-thiazolyl)-1H-benzimidazole …
Matched Iupac: … 2-(1,3-thiazol-4-yl)-1H-1,3-benzodiazole …
Matched Description: … 2-Substituted benzimidazole first introduced in 1962. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Tolnaftate is a synthetic over-the-counter anti-fungal agent. It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot and ringworm. It is sold under several brand names, most notably Tinactin and Odor Eaters.
Approved
Investigational
Vet approved
Matched Synonyms: … 2-Naphthyl N-methyl-N-(3-tolyl)thionocarbamate ... O-2-Naphthyl m,N-dimethylthiocarbanilate ... m,N-Dimethylthiocarbanilic acid O-2-naphthyl ester …
Matched Iupac: … N-methyl-N-(3-methylphenyl)-1-(naphthalen-2-yloxy)methanethioamide …
Matched Products: … FungaBlend 10 ... ครีมโทนาฟ 2% ... Opti-Nail 2-in-1 …
Displaying drugs 51 - 75 of 12032 in total