Advanced Filter

Filter by Group

Filter by Market Availability

Clear
Displaying drugs 51 - 75 of 426 in total

Moroctocog alfa

Moroctocog alfa, also known as BDDrFVIII (B domain deleted recombinant factor VIII), is a recombinant DNA-based drug with functional characteristics comparable to those of endogenous coagulation Factor VIII, the essential human blood clotting protein that is impaired in Hemophilia A. Moroctocog alfa is identical in sequence to endogenously produced Factor...
Approved
Matched Description: … purified Factor VIII from human pooled blood and contains both A- and B-subunits, and [DB11607], which ... Moroctocog alfa is approved by Health Canada and by the European Medicines Agency for the control and ... prevention of hemorrhagic episodes and for routine and surgical prophylaxis in patients with hemophilia …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Xyntha 250 IU Powder and Solvent for Solution for Injection ... Xyntha 1000 IU Powder and Solvent for Solution for Injection ... Xyntha 500 IU Powder and Solvent for Solution for Injection …

Antihemophilic factor (recombinant), PEGylated

Antihemophilic Factor (Recombinant), PEGylated, was approved by the FDA in December 2016 as the product Adynovate [FDA label]. Antihemophilic Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor VIII (2,332 amino acids with a molecular weight (MW) of approximately 280 kDa) covalently conjugated with at least one molecule of...
Approved
Investigational
Matched Description: … PEGylation decreases factor VIII clearance and allowing for an increased duration of drug circulation ... It has been created to increase the half-life of factor VIII, which decreases dose frequency and decreases …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ADYNOVATE 3000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 250 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 1000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …

Reteplase

Human tissue plasminogen activator, purified, glycosylated, 355 residues purified from CHO cells. Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA. Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA. Retavase...
Approved
Investigational
Matched Synonyms: … Human t-PA (residues 1-3 and 176-527) …
Matched Description: … Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains ... the activity-related kringle-2 and serine protease domains of human tPA. ... Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …

Colestipol

Bile acid sequestrants like colestipol have been in use since the 1970s.[FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia, colestipol is still generally only employed as...
Approved
Matched Synonyms: … Copolymer of bis(2-aminoethyl)amine and 2-(chloromethyl)oxirane …
Matched Description: … [FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated ... , colestipol is still generally only employed as an adjunct therapy and the relatively physical nature ... cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia …

Smallpox and Monkeypox Vaccine, Live, Non-replicating

Approved
Matched Name: … Smallpox and Monkeypox Vaccine, Live, Non-replicating …

Calcium ascorbate

Approved
Nutraceutical
Matched Mixtures name: … and Succinic Acid ... Threonate and Succinic Acid ... Vitamin C and Calcium Tab …
Matched Categories: … Diet, Food, and Nutrition ... Vitamin C and analogues …
Matched Products: … Ester-C With Non-medicinal Bioflavonoids, Quercetin, and Grape Seed Extract …

Degarelix

Degarelix is used for the treatment of advanced prostate cancer. Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH. This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately causes testosterone suppression. Reduction in...
Approved
Matched Description: … derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and ... This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents …
Matched Products: … Firmagon 120mg Powder and Solvent for Solution for Injection ... Firmagon 80mg Powder and Solvent for Solution for Injection ... FIRMAGON Powder and Solvent for Solution for Injection 120 mg …

Pasireotide

Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Approved
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Somatostatin and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … SIGNIFOR LAR(60 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... SIGNIFOR LAR (20 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... Signifor LAR 20mg powder and solvent for suspension for injection …

Goflikicept

Goflikicept is under investigation in clinical trial NCT04380519 (Study of the Efficacy and Safety of a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-cov-2) Infection (COVID-19)).
Investigational
Matched Synonyms: … a mutant Fc fragment of human IGg1 and part of human IL1 receptor accessory protein ... Heterodimeric fusion protein that binds to IL-1 beta consisting of human extracellular domain of IL1 receptor and …
Matched Description: … Goflikicept is under investigation in clinical trial NCT04380519 (Study of the Efficacy and Safety of ... a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe …

Lonoctocog alfa

Approved
Investigational
Matched Products: … AFSTYLA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 250IU/VIAL ... AFSTYLA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500IU/VIAL ... AFSTYLA 250IU powder and solvent for solution for injection …

Carboxymethylcellulose

Carboxymethylcellulose is a cellulose derivative that consists of the cellulose backbone made up of glucopyranose monomers and their hydroxyl groups bound to carboxymethyl groups. It is added in food products as a viscosity modifier or thickener and emulsifier. It is also one of the most common viscous polymers used in...
Approved
Investigational
Matched Description: … It is added in food products as a viscosity modifier or thickener and emulsifier. ... is a cellulose derivative that consists of the cellulose backbone made up of glucopyranose monomers and ... in the treatment of aqueous tear-deficient dry eye symptoms and ocular surface staining [A33029]. …
Matched Mixtures name: … Equate Day and Night Restore Tears ... Refresh Trial Pack (refresh Tears, Refresh Liquigel and Refresh Ultra) ... Refresh Trial Pack (refresh Tears, Refresh Liquigel and Refresh Ultra) …
Matched Categories: … Anorexigenic Agents & Respiratory and CNS Stimulants …
Matched Products: … Up and Up Lubricant ... Up and Up Lubricant Refreshing ... Up and Up Lubricant Refreshing Tears …

Albutrepenonacog alfa

Albutrepenonacog alfa (rIX-RFP) is a recombinant fusion protein that links a recombinant coagulation factor IX (rFIX) with a recombinant human albumin (rAlbumin). It was developed by CSL Behring Canada, Inc and approved by Health Canada on April 26, 2017. It was also approved by FDA and EMA in 2016. It...
Approved
Matched Description: … It was also approved by FDA and EMA in 2016. ... It is currently marketed in the forms of 250, 500, 1000 and 2000 IU/vial.[L2305] ... [A32547] It was developed by CSL Behring Canada, Inc and approved by Health Canada on April 26, 2017. …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Products: … IDELVION 250 IU powder and solvent for solution for injection ... IDELVION 500 IU powder and solvent for solution for injection ... IDELVION 1000 IU powder and solvent for solution for injection …

Rurioctocog alfa pegol

Rurioctocog alfa pegol is a pegylated recombinant human coagulation factor VIII or antihemophilic factor. Factor VIII is an essential protein involved in normal blood clotting; thus, a deficient level of functional factor VIII is associated with an elevated risk for excessive bleeding caused by spontaneous or secondary events like trauma...
Approved
Experimental
Matched Description: … Bleeding in joints is a common manifestation of hemophilia A, and bleeding episodes can be severe and ... alfa pegol aims to restore functional levels of factor VIII in patients with hemophilia A to manage and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ADYNOVATE 1500IU Powder and Solvent for Solution for Injection ... ADYNOVATE 2000IU Powder and Solvent for Solution for Injection ... ADYNOVATE 1000IU Powder and Solvent for Solution for Injection …

DCVAC/OvCa

DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo. It is under investigation for the treatment of ovarian cancer.
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo …
Matched Description: … DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and …

CHF5633

CHF5633 is a fully synthetic pulmonary surfactant preparation comprising DPPC (dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and a synthetic SP-B analogue.
Investigational
Matched Synonyms: … Synthetic surfactant comprised of DPPC, POPG Na, synthetic SP-C analogue and synthetic SP-B analogue …
Matched Description: … dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

VOR33

VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking the CD33 protein.
Investigational
Matched Synonyms: … allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking …
Matched Description: … VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy …

Petrolatum

A colloidal system of semisolid hydrocarbons obtained from petroleum. It is used as an ointment base, topical protectant, and lubricant.
Approved
Investigational
Matched Description: … It is used as an ointment base, topical protectant, and lubricant. …
Matched Mixtures name: … Coppertone Sport Lip Balm SPF 50 ... Alexander's Rash Ease - Sport Cream ... A and D Diaper Rash and Skin Protectant …
Matched Categories: … Basic Ointments and Protectants …
Matched Products: … Procurevitamin A and D Vitamin A and D ... A and D ... Vitamin A and D …

Coagulation factor VIIa Recombinant Human

Recombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the extrinsic pathway of the coagulation cascade. NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form.
Approved
Matched Description: … Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … NOVOSEVEN 2MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... powder and solvent for solution for injection 2mg ... powder and solvent for solution for injection 1mg …

Coagulation Factor IX (Recombinant)

Recombinant Coagulation Factor IX is a purified Factor IX glycoprotein produced by recombinant DNA technology. It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, and has structural and functional characteristics similar to those of endogenous factor IX. It is not...
Approved
Investigational
Matched Description: … Recombinant Factor IX is indicated for the control and prevention of bleeding episodes in adult and pediatric ... has structural and functional characteristics similar to those of endogenous factor IX. ... has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, and …
Matched Products: … BeneFIX , powder and solvent for solution for injection, 250 IU/Vial. ... BeneFIX Powder and Solvent for Solution for Injection 250iu/vial ... BeneFIX Powder and Solvent for Solution for Injection 1000iu/vial …

Dimethicone

Dimethicone is a silicone oil that is also known as polydimethylsiloxane (PDMS). It has viscoelastic properties. Dimethicone is used as a surfactant, antifoaming agent, carminative in various products such as medical devices, food products, and lubricants. It is used in a number of health and beauty products including hair care...
Approved
Matched Description: … for children and may serve as less toxic and less resistance-prone alternative to pesticide-containing ... , leave-in conditioner, and de-tangling products. ... surfactant, antifoaming agent, carminative in various products such as medical devices, food products, and …
Matched Mixtures name: … ChapStick Active Sport Ready ... Mentholatum Natural Ice Sport SPF 30 ... Silk and Shine …
Matched Categories: … Basic Ointments and Protectants ... Scabicides and Pediculicides ... Skin and Mucous Membrane Agents ... Antiparasitic Products, Insecticides and Repellents ... Scabicides, Insecticides and Repellents …
Matched Products: … Fresh Green Tea Seed Serum ... Hydropel Sports ... Truffle EX Retinol Spot …

ARGX-119

ARGX-119 is a monoclonal antibody that targets and activates muscle-specific kinase (MuSK).
Investigational
Matched Synonyms: … humanized immunoglobulin gamma 1 (IgG1) agonistic monoclonal antibody (mAb) that specifically targets and …
Matched Description: … ARGX-119 is a monoclonal antibody that targets and activates muscle-specific kinase (MuSK). …

Anbenitamab

Investigational
Matched Synonyms: … FC-fusion bispecific antibody targeting extracellular domains II and IV of HER 2 and FC-fusion bispecific ... IgG1 antibody inhibiting PD-L1 and CTLA-4 …

Linvoseltamab

Linvoseltamab is an investigational bispecific antibody. It promotes the interaction of B-cell maturation antigen (BCMA) on multiple myeloma cells with CD3-expressing T cells.
Investigational
Matched Synonyms: … human IgG4-based anti-CD3 x anti-BCMA bispecific monoclonal antibody that binds to CD3 and BCMA …

GTP-506

GTP-506 is a gene therapy formed by two vectors, a nuclease vector targeting gene editing in the well-characterized PCSK9 gene locus and a therapeutic donor vector that inserts the OTC gene to provide the desired genetic correction.
Investigational
Matched Synonyms: … Non-replicating recombinant adeno-associated virus serotype rh79 (AAVrh.79) vectors: AAVrh79.TBG.M2PCSK9.WPRE.bGH and …
Matched Description: … by two vectors, a nuclease vector targeting gene editing in the well-characterized PCSK9 gene locus and …

CVac

Approved
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with recombinant human fusion protein (MUCIN1 and Glutathione S Transferase …
Displaying drugs 51 - 75 of 426 in total