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Displaying drugs 726 - 750 of 3110 in total
Drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and penicillin-resistant Streptococcus penumoniae, represent a massive public health threat.[A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the previously approved linezolid and is generally effective against multidrug-resistant Gram-positive bacteria. Tedizolid is indicated for the...
Approved
Matched Synonyms: … Tedizolid phosphate ... Torezolid phosphate ... fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin-5-yl]methyl dihydrogen phosphate
Matched Name: … Tedizolid phosphate
Matched Iupac: … acid ... fluoro-4-[6-(2-methyl-2H-1,2,3,4-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin-5-yl]methoxy}phosphonic
Matched Description: … Tedizolid was approved by the FDA on June 20, 2014, for sale by Cubist Pharmaceuticals as tedizolid phosphate ... ) and is generally more effective and more tolerable than [linezolid]. ... such as methicillin-resistant _Staphylococcus aureus_, vancomycin-resistant _Enterococcus faecium_, and
Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. Their well-characterized anti-inflammatory activity, analgesic property, and established safety record have also made NSAIDs an important tool for optimizing surgical outcomes. Non-ophthalmic formulations of bromfenac were...
Approved
Withdrawn
Matched Synonyms: … [2-Amino-3-(4-bromo-benzoyl)-phenyl]-acetic acid ... 2-amino-3-(4-bromobenzoyl)benzeneacetic acid
Matched Iupac: … 2-[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid
Matched Description: … Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. ... Their well-characterized anti-inflammatory activity, analgesic property, and established safety record …
Matched Salts name: … Bromfenac sodium
Matched Products: … Bromfenac Sodium
Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid class that is marketed by Merck under the brand name Clinoril. Like other NSAIDs, it may be used in the treatment of acute or chronic inflammatory conditions. Sulindac is a prodrug, derived from sulfinylindene, that is converted in vivo...
Approved
Investigational
Matched Synonyms: … (Z)-5-Fluoro-2-methyl-1-((p-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid ... cis-5-Fluoro-2-methyl-1-((p-methylsulfinyl)benzylidene)indene-3-acetic acid ... cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid
Matched Iupac: … 2-[(1Z)-5-fluoro-1-[(4-methanesulfinylphenyl)methylidene]-2-methyl-1H-inden-3-yl]acetic acid
Matched Description: … Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid class that is marketed ... levels of the compound without inducing gastrointestinal effects, where the drug is excreted in the bile and ... is thought to primarily mediate its action by inhibiting prostaglandin synthesis by inhibiting COX-1 and
Matched Salts name: … Sulindac sodium
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Experimental
Matched Synonyms: … Xylitol 5-phosphate
Matched Name: … L-xylitol 5-phosphate
Matched Iupac: … {[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]oxy}phosphonic acid
Matched Categories: … Sugar Phosphates
Experimental
Matched Synonyms: … 2-(Hexadecanoylamino)acetic acid ... Elmiric acid
Matched Iupac: … 2-hexadecanamidoacetic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Fatty Acids
Indometacin, or indomethacin, is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic properties. NSAIDs consist of agents that are structurally unrelated; the NSAID chemical classification of indometacin is an indole-acetic acid derivative with the chemical name 1- (p-chlorobenzoyl)25-methoxy-2-methylindole-3-acetic acid. The pharmacological effect of indometacin is not fully understood,...
Approved
Investigational
Matched Synonyms: … 1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid ... {1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid
Matched Iupac: … 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid
Matched Description: … Drug Administration in 1965, [A486] along with other acetic acid derivatives such as [diclofenac] and ... acid derivative with the chemical name 1- (p-chlorobenzoyl)25-methoxy-2-methylindole-3-acetic acid. ... thromboxane biosynthesis via the arachidonic acid (AA) pathway. …
Matched Salts name: … Indomethacin sodium
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... indometacin and antiinfectives ... Topical Products for Joint and Muscular Pain …
Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.
Approved
Matched Description: … Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 ... peripheral origin, and as an adjuvant in the therapy of epilepsy. ... effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and
Matched Categories: … Calcium-Regulating Hormones and Agents ... Calcium Channel Blockers …
Matched Products: … FLUNARIZIN ACIS 5MG ... FLUNARIZIN ACIS 10MG …
Experimental
Matched Synonyms: … α-D-mannose 6-phosphate ... alpha-D-Mannopyranose 6-phosphate
Matched Name: … alpha-D-mannose 6-phosphate
Matched Iupac: … {[(2R,3S,4S,5S,6S)-3,4,5,6-tetrahydroxyoxan-2-yl]methoxy}phosphonic acid
Magnesium is classified as an alkaline earth metal and has 2 hydration shells. The element can be found in abundance in the hydrosphere and in mineral salts such as dolomite and magnesium carbonate. Common dietary sources of magnesium include nuts (cashews, peanuts, almonds), beans, bananas, apples, carrots, broccoli, and leafy...
Approved
Experimental
Investigational
Matched Description: … and magnesium carbonate. ... Magnesium is classified as an alkaline earth metal and has 2 hydration shells. ... [A32810] Further, the mineral helps regulate blood pressure and is necessary for RNA, DNA and protein …
Matched Mixtures name: … Liquid Calcium Mg Phosphorus and Vit.d-3 ... Calcium Folic Acid Plus D Chewable ... CALCIUM AND MAGNESIUM PLUS C,POTASSIUM AND ZINC TABLET …
Matched Products: … Kordel’s Magnesium Amino Acid Chelate 750 Capsules …
Atractylodes lancea root oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Atractyloides Japonica Root Oil …
Matched Name: … Atractylodes lancea root oil …
Matched Description: … Atractylodes lancea root oil is a plant/plant extract used in some OTC (over-the-counter) products. …
Procysteine has been used in trials studying the treatment of HIV Infections.
Investigational
Matched Synonyms: … (-)-2-OXO-4-THIAZOLIDINECARBOXYLIC ACID ... (R)-2-OXOTHIAZOLIDINE-4-CARBOXYLIC ACID ... 2-OXO-4-THIAZOLIDINECARBOXYLIC ACID, L- …
Matched Name: … Oxothiazolidinecarboxylic acid
Matched Iupac: … (4R)-2-oxo-1,3-thiazolidine-4-carboxylic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Imino Acids ... Amino Acids, Cyclic …
Experimental
Matched Synonyms: … Erythose-4-phosphate
Matched Name: … D-erythrose 4-phosphate
Matched Iupac: … [(2R,3R)-2,3-dihydroxy-4-oxobutoxy]phosphonic acid
Thiosulfuric acid is available in its salt forms sodium thiosulfate and sodium thiosulfate pentahydrate. Sodium thiosulfate is part of the World Health Organization’s list of essential medicines, and it has a variety of industrial uses, including food preservative, water de-chlorinator and paper pulp bleaching agent. Sodium thiosulfate is rapidly degraded...
Approved
Investigational
Matched Synonyms: … Sulfurothioic S-acid ... Monosulfanemonosulfonic acid
Matched Name: … Thiosulfuric acid
Matched Description: … ] and it is frequently used in conjunction with sodium nitrite (a salt form of [nitrous acid]). ... Thiosulfuric acid is available in its salt forms sodium thiosulfate and sodium thiosulfate pentahydrate ... Sodium thiosulfate is part of the World Health Organization’s list of essential medicines, and it has …
Matched Mixtures name: … Sodium polysulthionate and folic acid ... Sodium Polysulthionate and Folic Acid ... Sodium Polysulthionate, 5-mthf …
Matched Salts name: … Sodium thiosulfate ... Sodium thiosulfate pentahydrate …
Matched Categories: … Acids ... Sulfur Acids ... Sulfuric Acids
Matched Products: … Sodum Thiosulfate ... Sodium Thiosulfate ... SODIO TIOSOLFATO MONICO …
The chemical compound calcium acetate is the calcium salt of acetic acid. It has been commonly referred to as the acetate of lime. The anhydrous form is very hygroscopic, therefore the monohydrate is the common form.
Approved
Investigational
Matched Synonyms: … Calcio acetato ... Calcium acetate ... calcium ethanoate …
Matched Name: … Calcium acetate …
Matched Iupac: … calcium diacetate …
Matched Description: … The chemical compound calcium acetate is the calcium salt of acetic acid. …
Matched Salts name: … Calcium acetate monohydrate …
Matched Categories: … calcium acetate and magnesium carbonate ... ascorbic acid (vit C) and calcium ... Phosphate Binder ... Phosphate-removing Agents ... Alimentary Tract and Metabolism …
Matched Products: … Calcium Acetate ... Calcium Acetate 667 mg ... Calcium Acetate Tab 667mg …
Zomepirac, formerly marketed as Zomax tablets, was associated with fatal and near-fatal anaphylactoid reactions. The manufacturer voluntarily removed Zomax tablets from the Canadian, US, and UK markets in March 1983.
Withdrawn
Matched Synonyms: … 5-(4-Chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetic acid
Matched Iupac: … 2-[5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrol-2-yl]acetic acid
Matched Description: … Zomepirac, formerly marketed as Zomax tablets, was associated with fatal and near-fatal anaphylactoid ... The manufacturer voluntarily removed Zomax tablets from the Canadian, US, and UK markets in March 1983 …
Matched Salts name: … Zomepirac sodium ... Zomepirac sodium anhydrous …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Experimental
Matched Synonyms: … (2S)-2-Amino-4-(S-methylsufonimidoyl)butanoic acid ... BUTANOIC ACID, 2-AMINO-4-(S-METHYLSULFONIMIDOYL)-, (2S)- ... METHIONINE-DL-SULFOXIMINE …
Matched Iupac: … (2S)-2-amino-4-[imino(methyl)oxo-lambda6-sulfanyl]butanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Sulfur …
Investigational
Matched Synonyms: … 2-propenoic acid, 3-phenyl- ... Cinnamic acidum ... 3-phenylacrylic acid
Matched Name: … Cinnamic acid
Matched Iupac: … (2E)-3-phenylprop-2-enoic acid
Matched Categories: … Heparin and similars ... Acids, Carbocyclic ... Carboxylic Acids
Tarenflurbil is an investigational drug that was studied in patients with mild Alzheimer's disease. It is a selective amyloid lowering agent (SALA) that reduces levels of the toxic peptide amyloid beta 42 (Aβ42) in cultured human cells and in animal models. Aβ42 is the primary initiator of neurotoxicity and amyloid...
Investigational
Matched Synonyms: … (R)-2-fluoro-α-methyl(1,1'-biphenyl)-4-acetic acid ... (−)-(2R)-2-(2-fluorobiphenyl-4-yl)propanoic acid ... (2R)-2-(2-fluorobiphenyl-4-yl)propanoic acid
Matched Iupac: … (2R)-2-{2-fluoro-[1,1'-biphenyl]-4-yl}propanoic acid
Matched Description: … agent (SALA) that reduces levels of the toxic peptide amyloid beta 42 (Aβ42) in cultured human cells and ... Aβ42 is the primary initiator of neurotoxicity and amyloid plaque development in the brains of Alzheimer's …
Matched Categories: … Gamma Secretase Inhibitors and Modulators ... Acids, Acyclic ... Carboxylic Acids
Experimental
Matched Synonyms: … N-(indole-3-acetyl)aspartic acid ... N-(indol-3-ylacetyl)-L-aspartic acid ... N-(indol-3-ylacetyl)aspartic acid
Matched Name: … N-(indole-3-acetyl)-L-aspartic acid
Matched Iupac: … (2S)-2-[2-(1H-indol-3-yl)acetamido]butanedioic acid
Matched Categories: … Acids, Heterocyclic …
Experimental
Matched Synonyms: … Guanosine 3'-(dihydrogen phosphate) 5'-(trihydrogen diphosphate) …
Matched Iupac: … ]oxy}phosphonic acid ... ,5R)-4-hydroxy-5-(6-hydroxy-2-imino-3,9-dihydro-2H-purin-9-yl)-3-(phosphonooxy)oxolan-2-yl]methoxy})phosphoryl
Investigational
Matched Synonyms: … 5-Fluoro-2-methyl-1-((Z)-p-(methylsulfonyl)benzylidene)indene-3-acetic acid ... cis-5-Fluoro-2-methyl-1-(p-methylsulfonylbenzylidenyl)indene-3-acetic acid
Matched Iupac: … 2-[(1Z)-5-fluoro-1-[(4-methanesulfonylphenyl)methylidene]-2-methyl-1H-inden-3-yl]acetic acid
Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of acetaminophen overdose.[L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.[A228158,A228163,A228168] Acetylcysteine was granted FDA approval on 14 September 1963.
Approved
Investigational
Matched Synonyms: … N-acetyl-L-cysteine ... N-acetyl-L-(+)-cysteine ... (R)-mercapturic acid
Matched Iupac: … (2R)-2-acetamido-3-sulfanylpropanoic acid
Matched Description: … Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment …
Matched Mixtures name: … Levomefolate Calcium Acetylcysteine and Mecobalamin Algal ... Levomefolate Calcium, Acetylcysteine, Mecobalamin and Algal ... Levomefolate Calcium Acetylcysteine Mecobalamin Algal …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Sulfur …
Matched Products: … ACETIN ... ACETIN-200 ... ACETIN 200 …
A broad spectrum antimycotic with some action against Gram positive bacteria. It is used topically in dermatomycoses also orally and parenterally.
Approved
Matched Description: … It is used topically in dermatomycoses also orally and parenterally. …
Matched Mixtures name: … Econazole Nitrate 1% / Niacinamide 4% ... 071023 Econazole Nitrate 1% / Niacinamide 4% …
Matched Salts name: … Econazole nitrate
Matched Categories: … Genito Urinary System and Sex Hormones ... Imidazole and Triazole Derivatives ... Gynecological Antiinfectives and Antiseptics ... Metabolic Side Effects of Drugs and Substances ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Econazole Nitrate ... Econazole Nitrate Cream ... Econazole Nitrate Topical Foam, 1% …
Prednisolone is a glucocorticoid similar to cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone was granted FDA approval on 21 June 1955.
Approved
Vet approved
Matched Description: … glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and
Matched Categories: … Alimentary Tract and Metabolism ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Antineoplastic and Immunomodulating Agents ... Prednisolone and Prodrugs ... Sex Hormones and Insulins …
Matched Products: … PREDNISOLON ACIS 5MG ... PREDNISOLON ACIS 10MG ... PREDNISOLON ACIS 20MG …
Experimental
Matched Synonyms: … (+/-)-alpha-amino-4-hydroxybenzeneacetic acid ... dl-p-hydroxyphenylglycine …
Matched Iupac: … 2-amino-2-(4-hydroxyphenyl)acetic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids
Displaying drugs 726 - 750 of 3110 in total