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Displaying drugs 726 - 750 of 2551 in total
Naphazoline is a rapid acting imidazoline sympathomimetic vasoconstrictor of ocular or nasal artierioles[L5804,L5807]. It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations[L5804,L5807]. Naphazoline was first developed in 1942 as a nasal formulation for congestion .
Approved
Investigational
Matched Description: … It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations …
Matched Mixtures name: … OSMOCROM-N ® ... Medics Choice Eye Drops Maximum Redness Relief ... Naphazoline Hydrochloride and Pheniramine Maleate …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … DURAULTRA N SINE …
Hypromellose, or hydroxypropyl methylcellulose (HPMC) , is a semisynthetic, inert, and viscoelastic polymer that forms a colloid solution when dissolved in water. It acts as a thickening agent, coating polymer, bioadhesive, solubility enhancer in solid dispersions, and binder in the process of granulation and in modified release formulations . It...
Approved
Matched Description: … Hypromellose, or hydroxypropyl methylcellulose (HPMC) [L1812], is a semisynthetic, inert, and viscoelastic ... binder in the process of granulation and in modified release formulations [A24840]. ... acts as a thickening agent, coating polymer, bioadhesive, solubility enhancer in solid dispersions, and
Matched Mixtures name: … Rohto Sun and Sport ... NWI Artificial Tears Eye ... Quality Choice Lubricant Tears Eye …
Matched Products: … SIC OPHTAL N
The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class, chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking dopamine receptors. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
Approved
Investigational
Vet approved
Matched Synonyms: … 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethyl-1-propanamine ... 3-(2-chlorophenothiazin-10-yl)-N,N-dimethyl-propan-1-amine ... N-(3-dimethylaminopropyl)-3-chlorophenothiazine …
Matched Description: … Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the …
Ceramide NP is a lipid molecule included in a group of lipid molecules called ceramides. Ceramides are major lipid components in the stratum corneum of the human skin. Ceramide 3 consists of a phytosphingosine backbone N-acylated with a saturated fatty acid (stearic acid) . It is widely used as a...
Experimental
Matched Synonyms: … N-oleoylphytosphingosine ... N-octadecanoylphytosphingosine ... N-oloeoyl-4-hydroxysphinganine …
Matched Name: … Ceramide NP
Matched Iupac: … (9Z)-N-[(2S,3S,4R)-1,3,4-trihydroxyoctadecan-2-yl]octadec-9-enamide …
Matched Description: … It is widely used as a moisturizer in various cosmetic and personal products. ... Ceramide NP is a lipid molecule included in a group of lipid molecules called ceramides. ... Ceramide 3 consists of a phytosphingosine backbone N-acylated with a saturated fatty acid (stearic acid …
This is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (pyridoxamine).
Approved
Investigational
Nutraceutical
Matched Synonyms: … Pyridoxal 5-phosphate ... Pyridoxal 5'-phosphate ... Pyridoxal phosphate anhydrous …
Matched Name: … Pyridoxal phosphate
Matched Description: … phosphate (pyridoxamine). ... During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine …
Matched Mixtures name: … Levomefolate Calcium, Pyridoxal 5-phosphate, Methylcobalamin and Schizochytrium DHA Oil ... Levomefolate Calcium-Pyridoxal Phosphate-Mecobalamin ... Levomefolate Calcium Pyridoxal-5 Phosphate Mecobalamin Algal …
Matched Salts name: … Pyridoxal phosphate hydrate …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... pyridoxal phosphate
Valsartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes telmisartan, candesartan, losartan, olmesartan, and irbesartan. ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of aldosterone...
Approved
Investigational
Matched Synonyms: … N-(P-(O-1H-Tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valine ... (S)-N-Valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine ... N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine …
Matched Iupac: … (2S)-3-methyl-2-(N-{[2'-(2H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}pentanamido)butanoic acid …
Matched Description: … However, this does not prevent the formation of all angiotensin II within the body. ... aldosterone and ADH, cardiac stimulation, and renal reabsorption of sodium, among others. ... and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of …
Matched Mixtures name: … VARTERAL NF® 320 MG / 5 MG ... VARTERAL NF® 320 MG / 5 MG ... VARTERAL HCT NF® 160/10/12.5 …
Matched Categories: … Angiotensin II Antagonists and Calcium Channel Blockers ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... Angiotensin II Antagonists and Diuretics ... valsartan and nebivolol ... valsartan and diuretics …
Experimental
Matched Synonyms: … L-N-Carbamoylaspartic acid ... N-Carbamoylaspartic acid ... N-Carbamoyl-S-aspartic acid …
Matched Name: … N-Carbamoylaspartic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Cariprazine is an atypical antipsychotic agent and a piperazine derivative that was first developed in Hungary. It works as a partial agonist at central dopamine D2, dopamine D3, and serotonin 5-HT1A receptors and as an antagonist at serotonin 5-HT2A receptors. Cariprazine has been investigated in a variety of psychiatric disorders,...
Approved
Investigational
Matched Synonyms: … trans-N-{4-[2-[4-(2,3-dichlorophenyl)piperazine-1-yl]ethyl]cyclohexyl}-N’,N’-dimethylurea hydrochloride …
Matched Description: … [L41670] It is currently used to treat schizophrenia, and manic or mixed episodes and depressive episodes ... Cariprazine is an atypical antipsychotic agent and a piperazine derivative that was first developed in ... receptors and as an antagonist at serotonin 5-HT2A receptors. …
Nitenpyram is an insecticide used in agriculture and veterinary medicine to kill external parasites of pets. It is a neonicotinoid, a neurotoxin that blocks neural messages and binds particularly tightly in the central nervous system of insects, causing rapid death.
Experimental
Vet approved
Matched Synonyms: … (1E)-N-((6-chloro-3-pyridinyl)methyl)-N-ethyl-N'-methyl-2-nitro-1,1-ethenediamine …
Matched Description: … Nitenpyram is an insecticide used in agriculture and veterinary medicine to kill external parasites of ... It is a neonicotinoid, a neurotoxin that blocks neural messages and binds particularly tightly in the …
LY-2183240 is an inhibitor of endocannabinoid reuptake/breakdown.
Investigational
Matched Synonyms: … 1h-tetrazole-1-carboxamide, 5-((1,1'-biphenyl)-4-ylmethyl)-n,n-dimethyl- ... 5-(biphenyl-4-ylmethyl)-n,n-dimethyl-1h-tetrazole-1-carboxamide …
Matched Iupac: … 5-({[1,1'-biphenyl]-4-yl}methyl)-N,N-dimethyl-1H-1,2,3,4-tetrazole-1-carboxamide …
Experimental
Matched Name: … N-Cyclohexyl-N'-(4-Iodophenyl)Urea …
Experimental
Matched Name: … N-Cyclohexyl-N'-(Propyl)Phenyl Urea …
4-Phenylfentanyl is a sythetic opioid derived from fentanyl. 4-Phenylfentanyl is around 8x the potency of fentanyl in analgesic tests on animals, but more complex 4-heteroaryl derivatives such as substituted thiophenes and thiazoles are more potent still, as they are closer bioisosteres to the 4-carbomethoxy group of carfentanil.
Illicit
Matched Synonyms: … N-(1-Phenethyl-4-phenyl-4-piperidyl)-N-phenyl-propanamide …
Matched Iupac: … N-phenyl-N-[4-phenyl-1-(2-phenylethyl)piperidin-4-yl]propanamide …
Matched Description: … analgesic tests on animals, but more complex 4-heteroaryl derivatives such as substituted thiophenes and
Methylephedrine is a sympathomimetic amine that appears in various over-the-counter cough and cold medications throughout the world , , . The abuse of methylephedrine-containing medications has been reported in Japan. Methylephedrine is not legally available in the United States, but has been identified in cases of drug abuse .
Approved
Matched Synonyms: … (+/-)-N-methylephedrine ... N-methylephedrine DL-form …
Matched Description: … Methylephedrine is a sympathomimetic amine that appears in various over-the-counter cough and cold medications ... Methylephedrine is not legally available in the United States, but has been identified in cases of drug …
A vasodilator agent found to be effective in a variety of peripheral circulation disorders. It has various other potentially useful pharmacological effects. Its mechanism may involve block of calcium channels.
Experimental
Matched Synonyms: … 3-((1-Benzylcycloheptyl)oxy)-N,N-dimethylpropylamin …
Matched Description: … Its mechanism may involve block of calcium channels. …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Hydrocarbons, Cyclic ... Calcium Channel Blockers …
Decanoic acid is a solid. This compound belongs to the straight chain fatty acids. These are fatty acids with a straight aliphatic chain. The proteins that decanoic acid targets include furin, octanoyltransferase, 3-oxoacyl-[acyl-carrier-protein] synthase 1, peptostreptococcal albumin-binding protein, and putative uncharacterized protein tcp14.
Experimental
Matched Synonyms: … n-capric acid ... n-decylic acid ... n-decanoic acid …
Matched Description: … octanoyltransferase, 3-oxoacyl-[acyl-carrier-protein] synthase 1, peptostreptococcal albumin-binding protein, and
Celiprolol is indicated for the management of mild to moderate hypertension and effort-induced angina pectoris. It is simultaneously a selective β1 receptor antagonist, a β2 receptor partial agonist and a weak α2 receptor antagonist. In 2010 a clinical trial has suggested a use for this medication in the prevention of...
Approved
Investigational
Matched Synonyms: … RS)-N'-{3-acetyl-4-[3-(tert-butylamino)-2-hydroxypropoxy]phenyl}-N,N-diethylurea …
Matched Description: … Celiprolol is indicated for the management of mild to moderate hypertension and effort-induced angina ... It is simultaneously a selective β1 receptor antagonist, a β2 receptor partial agonist and a weak α2 ... Celiprolol is not approved for use by the FDA in the treatment of vascular Ehlers–Danlos syndrome. …
Matched Categories: … Hydrocarbons, Cyclic
Experimental
Matched Name: … 7-thionicotinamide-adenine-dinucleotide phosphate
Experimental
Illicit
Matched Synonyms: … n-ethyl MDA ... 3,4-methylenedioxy-N-ethylamphetamine …
An N-methylated indoleamine derivative, a serotonergic hallucinogen found in several plants, especially Prestonia amazonica (Apocynaceae) and in mammalian brain, blood, and urine. It apparently acts as an agonist at some types of serotonin receptors and an antagonist at others.
Experimental
Illicit
Matched Synonyms: … N,N-dimethyltryptamine ... N,N-dimethyl-1H-indole-3-ethylamine …
Matched Description: … An N-methylated indoleamine derivative, a serotonergic hallucinogen found in several plants, especially ... Prestonia amazonica (Apocynaceae) and in mammalian brain, blood, and urine. ... It apparently acts as an agonist at some types of serotonin receptors and an antagonist at others. …
Experimental
Matched Synonyms: … N-isopropyl-N'-hydroxyguanidine …
Matched Iupac: … (E)-N-hydroxy-N''-(propan-2-yl)guanidine …
A colorless liquid made by oxidation of aliphatic hydrocarbons that is used as a solvent and chemical intermediate.
Approved
Matched Synonyms: … N-propanol ... N-propyl alcohol …
Matched Description: … A colorless liquid made by oxidation of aliphatic hydrocarbons that is used as a solvent and chemical …
Matched Categories: … Antiseptics and Disinfectants …
Experimental
Matched Synonyms: … N-Methylcytosine …
Experimental
Matched Synonyms: … 5-methyluridine 5'-phosphate ... ribothymidine 5'-phosphate ... ribosylthymine 5'-phosphate
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Investigational
Matched Synonyms: … Furo(2,3-d)pyrimidin-4-amine, n-(4-methoxyphenyl)-n,2,6-trimethyl- ... N-(4-methoxyphenyl)-n,2,6-trimethylfuro(2,3-d) pyrimidin-4-amine …
Matched Iupac: … N-(4-methoxyphenyl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine …
Displaying drugs 726 - 750 of 2551 in total