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Displaying drugs 726 - 750 of 3569 in total
Investigational
Matched Synonyms: … Acido ippurico ... Benzamidoacetic acid ... Benzoylaminoacetic acid
Matched Name: … Hippuric acid
Matched Iupac: … 2-(phenylformamido)acetic acid
Matched Categories: … Benzamides and benzamide derivatives ... Acids, Carbocyclic ... Keto Acids ... Carboxylic Acids
Cilastatin is an inhibitor of renal dehydropeptidase, an enzyme responsible for both the metabolism of thienamycin beta-lactam antibiotics as well as conversion of leukotriene D4 to leukotriene E4. Since the antibiotic, imipenem, is one such antibiotic that is hydrolyzed by dehydropeptidase, cilastatin is used in combination with imipenem to prevent...
Approved
Investigational
Matched Synonyms: … (L)-7-(2-Amino-2-carboxy-ethylsulfanyl)-2-[(2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acid ... (R)-2-Amino-2-carboxy-ethylsulfanyl)-2-[((S)-2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acid
Matched Iupac: … )-7-{[(2R)-2-amino-2-carboxyethyl]sulfanyl}-2-{[(1S)-2,2-dimethylcyclopropyl]formamido}hept-2-enoic acid
Matched Mixtures name: … IMIPENEM MONOHYDRATE - CILASTATIN SODIUM ... IMIPENEM MONOHYDRATE / CILASTATIN SODIUM ... IMIPEMEM CILASTATINA SODICA
Matched Salts name: … Cilastatin sodium
Matched Categories: … imipenem and cilastatin ... imipenem, cilastatin and relebactam …
Matched Products: … Cilastatin Sodium Sterile …
Fondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and a O-methyl group at the reducing end of the molecule. It is structurally similar to polymeric glycosaminoglycan heparin and heparan sulfate (HS) when they are cleaved into monomeric units. The monomeric sequence in heparin and HS...
Approved
Investigational
Matched Iupac: … -hydroxy-6-methoxy-5-(sulfoamino)-2-[(sulfooxy)methyl]oxan-3-yl]oxy}-5-(sulfooxy)oxane-2-carboxylic acid
Matched Description: … It is structurally similar to polymeric glycosaminoglycan heparin and heparan sulfate (HS) when they ... Fondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and ... The monomeric sequence in heparin and HS is thought to form the high affinity binding site for the natural …
Matched Salts name: … Fondaparinux sodium
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … ARIXTRA (12.5 MG/ML) ... Fondaparinux Sodium ... FONDAPARINUX SODIUM
Ioxaglic acid is marketed as Hexabrix. This drug is an ionic tri-iodinated benzoate used as a low-osmolality contrast agent during diagnostic imaging procedures. Like other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray film, improving the visualization of important structures and organs during...
Approved
Investigational
Matched Synonyms: … Ioxaglic acid ... acido ioxaglico …
Matched Name: … Ioxaglic acid
Matched Iupac: … triiodo-5-(2-{[2,4,6-triiodo-3-(methylcarbamoyl)-5-(N-methylacetamido)phenyl]formamido}acetamido)benzoic acid
Matched Description: … Like other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray ... Ioxaglic acid has a low osmolarity and is associated with fewer side effects compared to older contrast ... , arthrography, cholangiography, urography, and computed tomography [L1889]. …
Matched Salts name: … Ioxaglate sodium
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... ioxaglic acid ... Triiodobenzoic Acids
Acetrizoic acid presents the molecular formula of 3-acetamidol-2,4,6-triiodobenzoic acid and it is the first monomeric ionic compound used as an X-ray contrast agent. It was first synthesized by Wallingford in 1953 and it was filled in the FDA by the Johnson & Johnson subsidiary, Cilag Chemie AG, on February 8th,...
Withdrawn
Matched Synonyms: … Urokonic acid ... Acide acetrizoique …
Matched Name: … Acetrizoic acid
Matched Iupac: … 3-acetamido-2,4,6-triiodobenzoic acid
Matched Description: … Acetrizoic acid presents the molecular formula of 3-acetamidol-2,4,6-triiodobenzoic acid[L1702] and it ... [A32135] It was first synthesized by Wallingford in 1953[A32136] and it was filled in the FDA by the ... [L1704] Acetrizoic acid presents, in the FDA records, a category of drug substance with an inactive status …
Matched Salts cas: … 129-63-5 …
Matched Salts name: … Acetrizoate sodium
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... acetrizoic acid ... Triiodobenzoic Acids
Investigational
Matched Synonyms: … 2-[4-(1-Methyl-4-pyridin-4-yl-lH-pyrazol-3-yl)-phenoxymethyl]-quinoline succinic acid
Trimetazidine is a piperazine derivative indicated for the symptomatic treatment of stable angina pectoris in patients inadequately controlled or intolerant to first line therapies. Trimetazidine has been studied as a treatment for angina pectoris since the late 1960s.[A233255,A233260] Acidic conditions, caused by anaerobic metabolism and fatty acid oxidation, in response...
Approved
Investigational
Matched Synonyms: … 1-[2,3,4-trimethoxybenzyl] piperazine dihydrochloride
Matched Description: … to myocardial ischemia, activate sodium-hydrogen and sodium-calcium antiport systems. ... [A233255,A233260] Acidic conditions, caused by anaerobic metabolism and fatty acid oxidation, in response ... oxidation but not glucose metabolism, preventing the acidic conditions that exacerbate ischemic injury …
Matched Salts name: … Trimetazidine dihydrochloride
Matched Products: … TRIMETAZIDINE DIHYDROCHLORIDE ... Trime MR (Trimetazidine Dihydrochloride MR Tablets 35mg) ... CARVIDON-MR (Trimetazidine Dihydrochloride Modified-Release Tablets 35 mg) …
A pyranoquinolone derivative that inhibits activation of inflammatory cells which are associated with asthma, including eosinophils, neutrophils, macrophages, mast cells, monocytes, and platelets.
Approved
Investigational
Matched Synonyms: … 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano(3,2-g)quinoline-2,8-dicarboxylic acid
Matched Iupac: … 9-ethyl-4,6-dioxo-10-propyl-4H,6H,9H-chromeno[7,6-b]pyridine-2,8-dicarboxylic acid
Matched Description: … are associated with asthma, including eosinophils, neutrophils, macrophages, mast cells, monocytes, and
Matched Salts name: … Nedocromil sodium
Matched Categories: … Decongestants and Antiallergics ... Decreased Histamine Release …
Matched Products: … Nedocromil Sodium
AMT-101 is a recombinant human interleukin-10 fusion protein.
Investigational
Matched Synonyms: … Recombinant human interleukin-10 fusion protein …
Matched Description: … AMT-101 is a recombinant human interleukin-10 fusion protein. …
Experimental
Matched Synonyms: … Acide nitrique ... Acido nitrico ... Nitric acid, anhydrous …
Matched Name: … Nitric acid
Matched Iupac: … nitric acid
Matched Categories: … Acids ... Acids, Noncarboxylic …
Tiaprofenic acid is a non-steroidal anti-inflammatory drug employed in the treatment of pain, particularly arthritis pain. It belongs to the arylpropionic acid (profen) group of nonsteroidal anti-inflammatory drugs (NSAIDs).
Approved
Matched Synonyms: … Tiaprofenic acid ... Acido tiaprofenico ... Acide tiaprofenique …
Matched Name: … Tiaprofenic acid
Matched Iupac: … 2-(5-benzoylthiophen-2-yl)propanoic acid
Matched Description: … Tiaprofenic acid is a non-steroidal anti-inflammatory drug employed in the treatment of pain, particularly ... It belongs to the _arylpropionic acid_ (profen) group of nonsteroidal anti-inflammatory drugs (NSAIDs …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Acyclic ... Fatty Acids ... Carboxylic Acids
Matched Products: … Teva-tiaprofenic Acid
A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
Experimental
Investigational
Matched Synonyms: … Butanoic acid ... Butyricum acidum ... N-butyric acid
Matched Name: … Butyric Acid
Matched Iupac: … butanoic acid
Matched Description: … A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the …
Matched Salts name: … Sodium butyrate …
Matched Categories: … Histamine Agents ... Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Products: … Sodium Butyrate …
Experimental
Matched Iupac: … 3,3-dimethyl-7-oxo-6-[(2R)-2-phenyl-2-sulfoacetamido]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Matched Salts name: … Sulbenicillin sodium
Matched Categories: … Sulfur Compounds …
Matched Products: … SULBENICILLIN SODIUM
Experimental
Matched Synonyms: … para-toluene sulfonate ... Tosic acid ... Tosylic acid
Matched Name: … p-Toluenesulfonic acid
Matched Iupac: … 4-methylbenzene-1-sulfonic acid
Matched Categories: … Sulfur Acids ... Sulfur Compounds ... Arylsulfonic Acids ... Sulfonic Acids
Pabinafusp alfa is under investigation in clinical trial NCT03568175 (A Study of JR-141 in Patients With Mucopolysaccharidosis II).
Investigational
Matched Synonyms: … ) FUSION PROTEIN WITH PEPTIDE (SYNTHETIC 2-AMINO ACID LINKER) FUSION PROTEIN WITH HUMAN IDURONATE-2-SULFATASE ... IMMUNOGLOBULIN G1, ANTI-(HUMAN TRANSFERRIN RECEPTOR) (HUMAN-MUS MUSCULUS MONOCLONAL JR-141 .GAMMA.1-CHAIN ... with human iduronate-2-sulfatase, glycoform alfa: …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Hydroxyethyl starch (HES/HAES) is a nonionic starch derivative. Hydroxyethyl starches (HES) are synthetic colloids commonly used for fluid resuscitation to replace intravascular volume. HES is a general term and can be sub-classified according to average molecular weight, molar substitution, concentration, C2/C6 ratio and Maximum Daily Dose.
Approved
Matched Description: … , concentration, C2/C6 ratio and Maximum Daily Dose. ... HES is a general term and can be sub-classified according to average molecular weight, molar substitution …
Matched Mixtures name: … Hydroxyethyl Starch in Sodium Chloride ... NEOHES %6 HES % 0.9 SODYUM KLORÜR İV İNFÜZYON İÇİN ÇÖZELTİ, 500 ML SETLİ ... NEOHES %6 HES % 0.9 SODYUM KLORÜR İV İNFÜZYON İÇİN ÇÖZELTİ, 500 ML SETSİZ …
Matched Categories: … Blood and Blood Forming Organs ... Blood and Related Products ... Blood Substitutes and Perfusion Solutions ... Blood Substitutes and Plasma Protein Fractions ... Blood Substitutes …
Matched Products: … Hetastarch in Sodium Chloride ... 6% Hetastarch In 0.9% Sodium Chloride …
Lormatazepam is an orally available benzodiazepine used in the UK for the treatment of short-term insomnia . It is marketed by Auden Mckenzie (Pharma Division) in 0.5 and 1 mg tablet formulations.
Approved
Matched Description: … It is marketed by Auden Mckenzie (Pharma Division) in 0.5 and 1 mg tablet formulations. …
Matched Categories: … Benzodiazepines and benzodiazepine derivatives ... Hypnotics and Sedatives …
Matched Products: … LORMETAZEPAM ACIS 0.5MG ... LORMETAZEPAM ACIS 1.0MG ... LORMETAZEPAM ACIS 2.0MG …
Avasopasem manganese, also known as GC4419, is a highly-selective small molecule mimetic of superoxide dismutase (SOD) being investigated for the reduction of radiation-induced severe oral mucositis.[L27246, L27256] This drug has potential application for radiation-induced esophagitis and oral mucositis, in addition to being currently tested against COVID-19.
Investigational
Matched Synonyms: … Avasopasem manganese
Matched Name: … Avasopasem manganese
Matched Description: … [L27246, L27256] This drug has potential application for radiation-induced esophagitis and oral mucositis ... Avasopasem manganese, also known as GC4419, is a highly-selective small molecule mimetic of superoxide …
Matched Salts name: … Avasopasem manganese
Experimental
Matched Synonyms: … alpha-Hydroxy-gamma-(methylthio)butyric acid ... alpha-Hydroxy-gamma-(methylmercapto)butyric acid ... 2-Hydroxy-4-(methylthio) butanoic acid
Matched Iupac: … 2-hydroxy-4-(methylsulfanyl)butanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Sulfur ... Sulfur Compounds ... Amino Acids ... Amino Acids, Neutral …
Experimental
Matched Synonyms: … (2S)-2-amino-3-(1-methyl-1H-imidazol-4-yl)propanoic acid ... 1-methyl-L-histidine ... N(tele)-methyl-L-histidine
Matched Iupac: … (2S)-2-amino-3-(1-methyl-1H-imidazol-4-yl)propanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic …
Investigational
Matched Synonyms: … human interleukin 2 fragment (1-59), variant (Cys125>Ser51), fused via peptidyl linker (60GG61) to human ... 75-133-interleukin 2 (125-serine) (human) fusion protein with peptide linker (gg) fusion protein with ... 75-133-Interleukin 2 [125-serine] (human) fusion protein with peptide linker (GG) fusion protein with …
Used as water softener, peptizing agent, emulsifier & dispersing agent; ingredient of cleansers; meat preservative.
Experimental
Matched Synonyms: … acide triphosphorique ... catena-triphosphoric acid ... tripolyphosphoric acid
Matched Name: … Triphosphoric acid
Matched Iupac: … {[hydroxy(phosphonooxy)phosphoryl]oxy}phosphonic acid
Matched Categories: … Acids ... Phosphoric Acids ... Acids, Noncarboxylic ... Phosphorus Acids
Flavoring agent sweeter than sugar, metabolized as phenylalanine and aspartic acid.
Investigational
Nutraceutical
Matched Synonyms: … 3-Amino-N-(α-methoxycarbonylphenethyl) succinamic acid ... 3-Amino-N-(alpha-methoxycarbonylphenethyl) succinamic acid ... 3-Amino-N-(α-carboxyphenethyl)succinamic acid N-methyl ester …
Matched Iupac: … (3S)-3-amino-3-{[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]carbamoyl}propanoic acid
Matched Description: … Flavoring agent sweeter than sugar, metabolized as phenylalanine and aspartic acid. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Diet, Food, and Nutrition …
Muplestim is under investigation in clinical trial NCT00002258 (A Phase I, Open Label Trial to Evaluate the Safety, Tolerance and Biological Effects of SDZ ILE-964 (Recombinant Human Interleukin-3, RhIL-3) in HIV Infected Patients With Cytopenia).
Investigational
Matched Synonyms: … Interleukin 3 (human) ... Human interleukin-3 (nonglycosylated) ... Interleukin-3 human (recombinant) …
Matched Description: … investigation in clinical trial NCT00002258 (A Phase I, Open Label Trial to Evaluate the Safety, Tolerance and ... Biological Effects of SDZ ILE-964 (Recombinant Human Interleukin-3, RhIL-3) in HIV Infected Patients …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Interleukins ... Interleukin-3 …
Investigational
Matched Name: … Autologous Human Peripheral Blood Lymphocytes …
Displaying drugs 726 - 750 of 3569 in total