Displaying drugs 726 - 750 of 2901 in total
AVA-4746
Investigational
Matched Synonyms: … 4-methylphenyl)propanoic acid ... )amino)carbonyl)amino)-4-methyl-, (.beta.s)- ... (3s)-3-(((1-(2-chlorobenzyl)-4-hydroxy-5-methyl-2-oxo-1,2-dihydropyridin-3yl)amino)carbonyl)amino-3-( …
Matched Iupac: … methyl]-4-hydroxy-5-methyl-2-oxo-1,2-dihydropyridin-3-yl}carbamoyl)amino]-3-(4-methylphenyl)propanoic acid …
Matched Iupac: … methyl]-4-hydroxy-5-methyl-2-oxo-1,2-dihydropyridin-3-yl}carbamoyl)amino]-3-(4-methylphenyl)propanoic acid …
Clesacostat
Clesacostat is under investigation in clinical trial NCT04321031 (Metabolic Interventions to Resolve Non-alcoholic Steatohepatitis (NASH) With Fibrosis (MIRNA)).
Investigational
Matched Synonyms: … pyridin-2-yl)benzoic acid ... )-1'-yl)carbonyl)-2-pyridinyl)- ... 4-(6-methoxy-4-(7-oxo-1-(propan-2-yl)-1,4,6,7-tetrahydrospiro(indazole-5,4'- piperidine)-1'-carbonyl) …
Orotidylic acid
Experimental
Matched Synonyms: … 6-carboxy-5'-uridylic acid …
Matched Name: … Orotidylic acid …
Matched Iupac: … -dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Name: … Orotidylic acid …
Matched Iupac: … -dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Urea
A compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.
Approved
Investigational
Matched Description: … It is the principal end product of protein catabolism and constitutes about one half of the total urinary ... A compound formed in the liver from ammonia produced by the deamination of amino acids. …
Matched Mixtures name: … Lactic Acid 10% / Urea 40% ... Urea 39.5% with 2% Salicylic Acid ... Hyaluronic Acid Sodium Salt 1% / Tacrolimus 0.1% / Urea 20% …
Matched Categories: … Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Emollients and Protectives …
Matched Products: … UREA ACIS 12% CREME ... Carmol 40 ... Carb-O-Philic …
Matched Mixtures name: … Lactic Acid 10% / Urea 40% ... Urea 39.5% with 2% Salicylic Acid ... Hyaluronic Acid Sodium Salt 1% / Tacrolimus 0.1% / Urea 20% …
Matched Categories: … Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Emollients and Protectives …
Matched Products: … UREA ACIS 12% CREME ... Carmol 40 ... Carb-O-Philic …
Bufexamac
Bufexamac is a non-steroidal anti-inflammatory drug (NSAID) under the market name Droxaryl, Malipuran, Paraderm and Parfenac. It is typically administered topically for the treatment of subacute and chronic eczema of the skin, including atopic eczema and other inflammatory dermatoses, as well as sunburn and other minor burns, and itching. It...
Approved
Withdrawn
Matched Synonyms: … Bufexamic acid ... 4-Butoxyphenylacetohydroxamic acid ... 2-(p-Butoxyphenyl)-acetohydroxamic acid …
Matched Description: … and itching. ... including atopic eczema and other inflammatory dermatoses, as well as sunburn and other minor burns, ... a non-steroidal anti-inflammatory drug (NSAID) under the market name Droxaryl, Malipuran, Paraderm and …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain ... Hydroxy Acids …
Matched Description: … and itching. ... including atopic eczema and other inflammatory dermatoses, as well as sunburn and other minor burns, ... a non-steroidal anti-inflammatory drug (NSAID) under the market name Droxaryl, Malipuran, Paraderm and …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain ... Hydroxy Acids …
Carbenicillin
Broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function.
Approved
Investigational
Matched Synonyms: … N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)hept-6-yl)-2-phenylmalonamic acid ... acid ... (2S,5R,6R)-6-{[carboxy(phenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic …
Matched Iupac: … acid ... (2S,5R,6R)-6-(2-carboxy-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic …
Matched Description: … It is susceptible to gastric juice and penicillinase and may damage platelet function. …
Matched Iupac: … acid ... (2S,5R,6R)-6-(2-carboxy-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic …
Matched Description: … It is susceptible to gastric juice and penicillinase and may damage platelet function. …
Avizakimab
Avizakimab is under investigation in clinical trial NCT03371251 (Study of BOS161721 in Systemic Lupus Erythematosus (SLE) Patients on a Background of Limited Standard of Care).
Investigational
Matched Synonyms: … Immunoglobulin g1 (251-tyrosine,253-threonine,255-glutamic acid), anti-(human interleukin 21) (human-mus ... musculus monoclonal bos161721 .gamma.1-chain), disulfide with human-mus musculus monoclonal bos161721 …
SLC-0111
Investigational
Matched Synonyms: … 4-[[[(4-Fluorophenyl)amino]carbonyl]amino]benzenesulfonamide ... Benzenesulfonamide, 4-[[[(4-fluorophenyl)amino]carbonyl]amino]- …
Butyric Acid
A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
Experimental
Investigational
Matched Synonyms: … Butanoic acid ... N-butyric acid ... Butyricum acidum …
Matched Name: … Butyric Acid …
Matched Iupac: … butanoic acid …
Matched Description: … A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Name: … Butyric Acid …
Matched Iupac: … butanoic acid …
Matched Description: … A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Lumacaftor
Lumacaftor is a drug used in combination with DB08820 as the fixed dose combination product Orkambi for the management of Cystic Fibrosis (CF) in patients aged 6 years and older. Cystic Fibrosis is an autosomal recessive disorder caused by one of several different mutations in the gene for the Cystic...
Approved
Matched Synonyms: … acid ... 3-(6-{[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-carbonyl]amino}-3-methylpyridin-2-yl)benzoic …
Matched Iupac: … 3-{6-[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropaneamido]-3-methylpyridin-2-yl}benzoic acid …
Matched Description: … [FDA Label] This data has been heavily scrutinized, however, with clinical trials showing only modest ... with CF worldwide, is known as F508del-CFTR, or delta-F508 (ΔF508), in which a deletion in the amino acid ... dose combination product Orkambi for the management of Cystic Fibrosis (CF) in patients aged 6 years and …
Matched Categories: … ivacaftor and lumacaftor …
Matched Iupac: … 3-{6-[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropaneamido]-3-methylpyridin-2-yl}benzoic acid …
Matched Description: … [FDA Label] This data has been heavily scrutinized, however, with clinical trials showing only modest ... with CF worldwide, is known as F508del-CFTR, or delta-F508 (ΔF508), in which a deletion in the amino acid ... dose combination product Orkambi for the management of Cystic Fibrosis (CF) in patients aged 6 years and …
Matched Categories: … ivacaftor and lumacaftor …
Tobevibart
Tobevibart is under investigation in clinical trial NCT05612581 (A Platform Study to Evaluate Investigational Therapies in Chronic Hepatitis B Infection).
Investigational
Matched Synonyms: … Immunoglobulin G1 [238-alanine,332-leucine,334-glutamic acid,430-leucine,436-serine], anti-(hepatitis ... B virus surface antigen) (human monoclonal VIR-3434 γ1-chain), disulfide with human monoclonal VIR-3434 …
Indomethacin
Indometacin, or indomethacin, is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic properties. NSAIDs consist of agents that are structurally unrelated; the NSAID chemical classification of indometacin is an indole-acetic acid derivative with the chemical name 1- (p-chlorobenzoyl)25-methoxy-2-methylindole-3-acetic acid. The pharmacological effect of indometacin is not fully understood,...
Approved
Investigational
Matched Synonyms: … {1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid ... 1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid …
Matched Iupac: … 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid …
Matched Description: … Drug Administration in 1965, [A486] along with other acetic acid derivatives such as [diclofenac] and ... Indometacin was first discovered in 1963 and it was first approved for use in the U.S. by the Food and ... ocular inflammation and pain and/or complications after cataract surgery. …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... indometacin and antiinfectives ... Topical Products for Joint and Muscular Pain …
Matched Iupac: … 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid …
Matched Description: … Drug Administration in 1965, [A486] along with other acetic acid derivatives such as [diclofenac] and ... Indometacin was first discovered in 1963 and it was first approved for use in the U.S. by the Food and ... ocular inflammation and pain and/or complications after cataract surgery. …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... indometacin and antiinfectives ... Topical Products for Joint and Muscular Pain …
Cyclacillin
A cyclohexylamido analog of penicillanic acid.
Approved
Matched Synonyms: … (2S,5R,6R)-6-{[(1-aminocyclohexyl)carbonyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane ... -2-carboxylic acid ... 6-(1-aminocyclohexylcarboxamido)penicillanic acid …
Matched Iupac: … 5R,6R)-6-(1-aminocyclohexaneamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … A cyclohexylamido analog of penicillanic acid. …
Matched Iupac: … 5R,6R)-6-(1-aminocyclohexaneamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … A cyclohexylamido analog of penicillanic acid. …
Natalizumab
Natalizumab is a recombinant humanized IgG4κ monoclonal antibody that binds to α4-integrin. While natalizumab was originally approved by the FDA to treat multiple sclerosis in 2004, it was withdrawn from the market following multiple reports of fatal progressive multifocal leukoencephalopathy (PML). In 2006, the FDA reintroduced the drug to the...
Approved
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4 (HUMAN-MOUSE MONOCLONAL AN100226 4-CHAIN ANTI-HUMAN INTEGRIN 4), DISULFIDE WITH HUMAN-MOUSE ... IMMUNOGLOBULIN G4 (HUMAN-MOUSE MONOCLONAL AN100226 4-CHAIN ANTI-HUMAN INTEGRIN 4), DISULPHIDE WITH HUMAN-MOUSE …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Ticarcillin
An antibiotic derived from penicillin similar to carbenicillin in action.
Approved
Investigational
Vet approved
Matched Synonyms: … ]heptane-2-carboxylic acid ... α-carboxy-3-thienylmethylpenicillin ... (2S,5R,6R)-6-{[(2R)-2-carboxy-2-thiophen-3-ylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0 …
Matched Iupac: … ]heptane-2-carboxylic acid ... (2S,5R,6R)-6-[(2R)-2-carboxy-2-(thiophen-3-yl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0 …
Matched Iupac: … ]heptane-2-carboxylic acid ... (2S,5R,6R)-6-[(2R)-2-carboxy-2-(thiophen-3-yl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0 …
Quisovalimab
Investigational
Matched Synonyms: … Immunoglobulin G4 [230-proline,237-glutamic acid], anti-(human tumor necrosis factor superfamily protein ... TNFSF14) (human-Mus musculus monoclonal SAR252067 γ4-chain), disulfide with human-Mus musculus monoclonal …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Prednisone
A synthetic anti-inflammatory glucocorticoid derived from cortisone. It is biologically inert and converted to prednisolone in the liver. Prednisone was granted FDA approval on 21 February 1955.
Approved
Vet approved
Matched Description: … [A187463] It is biologically inert and converted to [prednisolone] in the liver. …
Matched Categories: … Alimentary Tract and Metabolism ... Prednisolone and Prodrugs ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … PREDNISON ACIS 5MG ... PREDNISON ACIS 20MG ... PREDNISON ACIS 50MG …
Matched Categories: … Alimentary Tract and Metabolism ... Prednisolone and Prodrugs ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … PREDNISON ACIS 5MG ... PREDNISON ACIS 20MG ... PREDNISON ACIS 50MG …
Fotemustine
Investigational
Matched Synonyms: … PHOSPHONIC ACID, (1-((((2-CHLOROETHYL)NITROSOAMINO)CARBONYL)AMINO)ETHYL)-, DIETHYL ESTER ... PHOSPHONIC ACID, P-(1-((((2-CHLOROETHYL)NITROSOAMINO)CARBONYL)AMINO)ETHYL)-, DIETHYL ESTER …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Linoleic acid
Approved
Experimental
Matched Synonyms: … Linolic acid ... acide linoléique ... acide cis-linoléique …
Matched Name: … Linoleic acid …
Matched Iupac: … (9Z,12Z)-octadeca-9,12-dienoic acid …
Matched Categories: … Fatty Acids ... Linoleic Acids ... Fatty Acids, Omega-6 ... Fatty Acids, Essential ... Fatty Acids, Unsaturated …
Matched Name: … Linoleic acid …
Matched Iupac: … (9Z,12Z)-octadeca-9,12-dienoic acid …
Matched Categories: … Fatty Acids ... Linoleic Acids ... Fatty Acids, Omega-6 ... Fatty Acids, Essential ... Fatty Acids, Unsaturated …
Mapatumumab
Mapatumumab is under investigation in clinical trial NCT00094848 (Study of TRM-1 (TRAIL-R1 Monoclonal Antibody) in Subjects With Relapsed or Refractory Non-hodgkin's Lymphoma (NHL)).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human cytokine receptor dr4 (death receceptor 4)) (human monoclonal trm-1 heavy chain), disulfide ... Immunoglobulin g1, anti-(human trail-r1) (human monoclonal trm-1 heavy chain), disulfide with human monoclonal ... Immunoglobulin g1, anti-(human cytokine receptor dr4 (death receceptor 4)) (human monoclonal trm-1 heavy chain), disulphide …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Hyoscyamine
Hyoscyamine is a tropane alkaloid and the levo-isomer of atropine. It is commonly extracted from plants in the Solanaceae or nightshade family. Research into the action of hyoscyamine in published literature dates back to 1826. Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic...
Approved
Matched Synonyms: … Daturin ... [3(S)-endo]-α-(hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester …
Matched Description: … Hyoscyamine is a tropane alkaloid and the levo-isomer of [atropine]. ... [A228713] Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic …
Matched Mixtures name: … Phenazopyridine Hydrochloride, Hyoscyamine Hydrobromide, and Butabarbital ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide …
Matched Categories: … Alimentary Tract and Metabolism ... Belladonna and Derivatives, Plain ... hyoscyamine and psycholeptics …
Matched Description: … Hyoscyamine is a tropane alkaloid and the levo-isomer of [atropine]. ... [A228713] Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic …
Matched Mixtures name: … Phenazopyridine Hydrochloride, Hyoscyamine Hydrobromide, and Butabarbital ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide …
Matched Categories: … Alimentary Tract and Metabolism ... Belladonna and Derivatives, Plain ... hyoscyamine and psycholeptics …
Iodoxamic acid
Radiopaque medium used in the diagnosis of gall bladder & bile duct diseases, usually as meglumine salt.
Experimental
Matched Synonyms: … Iodoxamic acid ... Acidum iodoxamicum …
Matched Name: … Iodoxamic acid …
Matched Iupac: … acid ... 3-{1-[(3-carboxy-2,4,6-triiodophenyl)carbamoyl]-3,6,9,12-tetraoxapentadecan-15-amido}-2,4,6-triiodobenzoic …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... iodoxamic acid …
Matched Name: … Iodoxamic acid …
Matched Iupac: … acid ... 3-{1-[(3-carboxy-2,4,6-triiodophenyl)carbamoyl]-3,6,9,12-tetraoxapentadecan-15-amido}-2,4,6-triiodobenzoic …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... iodoxamic acid …
Isosorbide mononitrate
Isosorbide mononitrate is an organic nitrate with vasodilating properties. It is an anti-anginal agent that works by relaxing the smooth muscles of both arteries and veins, but but predominantly veins to reduce cardiac preload.[L11698, L11743] Isosorbide mononitrate is an active metabolite of isosorbide dinitrate. Like other organic nitrates, isosorbide mononitrate...
Approved
Matched Synonyms: … Isosorbide 5-nitrate …
Matched Iupac: … (3R,3aS,6S,6aR)-6-hydroxy-hexahydrofuro[3,2-b]furan-3-yl nitrate …
Matched Description: … [L11698] It is available in oral tablets generically and under the brand name ISMO and Monoket. ... It is an anti-anginal agent that works by relaxing the smooth muscles of both arteries and veins, but ... mononitrate has a longer duration of action than [nitroglycerin] due to its slow onset of absorption and …
Matched Categories: … Nitrates and Nitrites ... Organic Nitrates ... Nitrate Vasodilator …
Matched Products: … NITRARD …
Matched Iupac: … (3R,3aS,6S,6aR)-6-hydroxy-hexahydrofuro[3,2-b]furan-3-yl nitrate …
Matched Description: … [L11698] It is available in oral tablets generically and under the brand name ISMO and Monoket. ... It is an anti-anginal agent that works by relaxing the smooth muscles of both arteries and veins, but ... mononitrate has a longer duration of action than [nitroglycerin] due to its slow onset of absorption and …
Matched Categories: … Nitrates and Nitrites ... Organic Nitrates ... Nitrate Vasodilator …
Matched Products: … NITRARD …
Sotigalimab
Sotigalimab is under investigation in clinical trial NCT03123783 (CD40 Agonistic Antibody APX005M in Combination With Nivolumab).
Investigational
Matched Synonyms: … CUNICULUS MONOCLONAL APX005M .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-ORYCTOLAGUS CUNICULUS MONOCLONAL ... IMMUNOGLOBULIN G1 (270-GLUTAMIC ACID, C-TERMINAL-LYSINE-CLIPPED), ANTI-(HUMAN CD40 ANTIGEN) (HUMAN-ORYCTOLAGUS …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Exlinkibart
Investigational
Matched Synonyms: … Immunoglobulin G1 (de-236-glycine,267-glutamic acid,de-C-terminal lysine), anti-(human tumor necrosis ... factor receptor TNFRSF9) (human-mus musculus monoclonal lvgn6051 .hamma.1-chain), disulfide with human-mus …
Displaying drugs 726 - 750 of 2901 in total