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Displaying drugs 7476 - 7500 of 11861 in total

Haloxon

Vet approved
Matched Iupac: … 3-chloro-4-methyl-2-oxo-2H-chromen-7-yl bis(2-chloroethyl) phosphate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Zelavespib

Zelavespib (PU-H71) has been used in trials studying the treatment of LYMPHOMA, Solid Tumors, Metastatic Solid Tumor, and Myeloproliferative Neoplasms (MPN).
Investigational
Matched Iupac: … 8-[(6-iodo-2H-1,3-benzodioxol-5-yl)sulfanyl]-9-{3-[(propan-2-yl)amino]propyl}-9H-purin-6-amine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

MK-0873

MK-0873 has been used in trials studying the treatment of Rheumatoid Arthritis.
Investigational
Matched Iupac: … 3-(2-{3-[3-(cyclopropylcarbamoyl)-4-oxo-1,4-dihydro-1,8-naphthyridin-1-yl]phenyl}ethynyl)pyridin-1-ium …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Ambroxol acefyllinate

Experimental
Investigational
Matched Iupac: … (1r,4r)-4-{[(2-amino-3,5-dibromophenyl)methyl]amino}cyclohexan-1-ol; 2-(1,3-dimethyl-2,6-dioxo-2,3,6,7 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

AZD-8186

AZD-8186 is under investigation in clinical trial NCT03218826 (PI3Kbeta Inhibitor AZD8186 and Docetaxel in Treating Patients Advanced Solid Tumors With PTEN or PIK3CB Mutations That Are Metastatic or Cannot Be Removed by Surgery).
Investigational
Matched Iupac: … 8-[(1R)-1-[(3,5-difluorophenyl)amino]ethyl]-N,N-dimethyl-2-(morpholin-4-yl)-4-oxo-4H-chromene-6-carboxamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Chrysin

Experimental
Matched Iupac: … 5,7-dihydroxy-2-phenyl-4H-chromen-4-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

TRX-E-002-1

Investigational
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Ocaperidone

Investigational
Matched Iupac: … 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-2,9-dimethyl-4H-pyrido[1,2-a]pyrimidin-4- …

(3S,5E)-3-propyl-3,4-dihydrothieno[2,3-f][1,4]oxazepin-5(2H)-imine

Experimental

Coproporphyrinogen III

Experimental
Matched Iupac: … 3-[9,14,20-tris(2-carboxyethyl)-5,10,15,19-tetramethyl-21,22,23,24-tetraazapentacyclo[16.2.1.1^{3,6}.1 …

Poloxamer 237

Experimental

Troriluzole

Troriluzole is under investigation in clinical trial NCT03701399 (Troriluzole in Adult Subjects With Spinocerebellar Ataxia).
Investigational
Matched Iupac: … 2-amino-N-{[methyl({[6-(trifluoromethoxy)-1,3-benzothiazol-2-yl]carbamoyl}methyl)carbamoyl]methyl}acetamide …

Ifenprodil

N-methyl-D-aspartate (NMDA) receptors (NMDARs) are members of the ionotropic glutamate receptor family, with key roles in brain development and neurological function.[A220118, A220128] NMDARs are heterotetramers that typically involve a dimer of dimers of both GluN1 and GluN2A-D subunits, with each subunit itself composed of an N-terminal domain (NTD), a ligand-binding...
Investigational
Withdrawn
Matched Iupac: … 4-[2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl]phenol …

Sofinicline

Sofinicline has been used in trials studying the treatment of ADHD, Neuralgia, Diabetic, Diabetic Neuropathies, Diabetic Polyneuropathy, and Diabetic Neuropathic Pain, among others.
Investigational

2,2'-{[9-(HYDROXYIMINO)-9H-FLUORENE-2,7-DIYL]BIS(OXY)}DIACETIC ACID

Experimental
Matched Iupac: … 2-{[7-(carboxymethoxy)-9-(hydroxyimino)-9H-fluoren-2-yl]oxy}acetic acid …

S-Adenosyl-1,8-Diamino-3-Thiooctane

Experimental
Matched Iupac: … (2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-{[(1,8-diaminooct-2-en-3-yl)sulfanyl]methyl}oxolane-3,4-diol …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

5'-Fluoro-5'-Deoxyadenosine

Experimental
Matched Iupac: … (2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-(fluoromethyl)oxolane-3,4-diol …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Isatoribine

Isatoribine is a selective agonist of TLR7.
Investigational
Matched Iupac: … 5-amino-3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2H,3H,4H,7H-[1,3]thiazolo[4,5-d] …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Pavinetant

Pavinetant has been used in trials studying the basic science and treatment of Safety and Schizophrenia.
Investigational
Matched Iupac: … 3-methanesulfonamido-2-phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Epicatechin

Epicatechin has been used in trials studying the treatment of Pre-diabetes.
Investigational
Matched Iupac: … (2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Ibodutant

Ibodutant has been used in trials studying the treatment of Irritable Bowel Syndrome and Irritable Bowel Syndrome With Diarrhea.
Investigational
Matched Iupac: … }cyclopentyl)-1-benzothiophene-2-carboxamide ... 6-methyl-N-(1-{[(1R)-1-[({1-[(oxan-4-yl)methyl]piperidin-4-yl}methyl)carbamoyl]-2-phenylethyl]carbamoyl …
Matched Categories: … Receptors, Neurokinin-2, antagonists & inhibitors …

Iguratimod

Iguratimod is under investigation in Rheumatoid Arthritis.
Investigational
Matched Categories: … Heterocyclic Compounds, 2-Ring …

GDC-0810

ARN-810 has been used in trials studying the basic science and treatment of Breast Cancer.
Investigational
Matched Iupac: … (2E)-3-{4-[(1E)-2-(2-chloro-4-fluorophenyl)-1-(1H-indazol-5-yl)but-1-en-1-yl]phenyl}prop-2-enoic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Toreforant

Toreforant has been used in trials studying the treatment of Asthma, Psoriasis, Hepatic Impairment, and Rheumatoid Arthritis.
Investigational
Matched Iupac: … 5-(4,6-dimethyl-1H-1,3-benzodiazol-2-yl)-4-methyl-N-[3-(1-methylpiperidin-4-yl)propyl]pyrimidin-2-amine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Setipiprant

Setipiprant has been investigated for the treatment of Seasonal Allergic Rhinitis.
Investigational
Matched Iupac: … 2-[8-fluoro-2-(naphthalene-1-carbonyl)-1H,2H,3H,4H,5H-pyrido[4,3-b]indol-5-yl]acetic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Displaying drugs 7476 - 7500 of 11861 in total