Displaying drugs 7601 - 7625 of 12049 in total
4-(4-FLUOROBENZYL)PIPERIDINE
Experimental
Matched Name: … 4-(4-FLUOROBENZYL)PIPERIDINE …
Matched Iupac: … 4-[(4-fluorophenyl)methyl]piperidine …
Matched Iupac: … 4-[(4-fluorophenyl)methyl]piperidine …
PEN-866
PEN-866 is under investigation in clinical trial NCT03221400 (PEN-866 in Patients With Advanced Solid Malignancies).
Investigational
Matched Iupac: … 21),2,4,6,8,10,15(20)-heptaen-7-yl 4-[2-(5-{3-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-5-oxo-4,5-dihydro ... -1H-1,2,4-triazol-4-yl}-1H-indol-1-yl)ethyl]piperidine-1-carboxylate ... diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1( …
Recombinant human CD4 immunoglobulin G
Investigational
Alvocidib
Alvocidib is a synthetic flavonoid based on an extract from an Indian plant for the potential treatment of cancer. It works by inhibiting cyclin-dependent kinases, arresting cell division and causing apoptosis in non-small lung cancer cells.
Experimental
Investigational
Matched Iupac: … 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]-4H-chromen-4-one …
Matched Salts cas: … 131740-09-5 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Salts cas: … 131740-09-5 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Reproterol
Reproterol has been used in trials studying the treatment of Asthma, Exercise-Induced.
Investigational
5-Formyl-2'-deoxy-cytidine-5'-monophosphate
Experimental
Matched Name: … 5-Formyl-2'-deoxy-cytidine-5'-monophosphate …
Matched Iupac: … {[(2R,3S,5R)-5-(4-amino-5-formyl-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}phosphonic …
Matched Iupac: … {[(2R,3S,5R)-5-(4-amino-5-formyl-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}phosphonic …
Elsamitrucin
The cytostatic agent Elsamitrucin is a new fermentation product active in a variety of in vivo tumor models of murine and human origin. (PMID: 8150873)
Investigational
Matched Iupac: … 3-{[(2S,3R,4S,5S,6R)-3-{[(2R,3R,4R,5S,6R)-3-amino-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-4,5-dihydroxy ... dimethyloxan-2-yl]oxy}-8-hydroxy-15-methyl-11,18-dioxapentacyclo[10.6.2.0^{2,7}.0^{9,19}.0^{16,20}]icosa-1( …
Human Recombinant Bone Morphogenetic Protein 4
Investigational
Matched Synonyms: … RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN 4 …
Matched Name: … Human Recombinant Bone Morphogenetic Protein 4 …
Matched Name: … Human Recombinant Bone Morphogenetic Protein 4 …
Brotizolam
Brotizolam is a sedative-hypnotic thienodiazepine drug which is a benzodiazepine analog. It demonstrates anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant effects. Brotizolam has similar effects to short-acting benzodiazepines such as triazolam. Brotizolam is indicated for 2-4 weeks of treatment for severe or debilitating insomnia. Brotizolam is an extremely potent...
Investigational
Withdrawn
Matched Iupac: … 4-bromo-7-(2-chlorophenyl)-13-methyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12 …
Matched Description: … Brotizolam is indicated for 2-4 weeks of treatment for severe or debilitating insomnia. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Brotizolam is indicated for 2-4 weeks of treatment for severe or debilitating insomnia. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
(4R)-7-Aza-7,8-dihydrolimonene
Experimental
Matched Iupac: … (1R)-N,N,4-trimethylcyclohex-3-en-1-amine …
Mibenratide
Mibenratide is under investigation in clinical trial NCT01798745 (A Study to Assess the Pharmacokinetics and Pharmacodynamics of JNJ-54452840 in Participants With Heart Failure and Anti-beta1-adrenergic Receptor Autoantibodies).
Investigational
Matched Iupac: … 3-[(1R,4S,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R,40S,43S,49S,52S,55S)-40-(4-aminobutyl)-28-benzyl ... carbamimidamidopropyl)-22-(2-carbamoylethyl)-52-(carbamoylmethyl)-16,31,49-tris(carboxymethyl)-34-(hydroxymethyl)-55-[(4- …
Atabecestat
Atabecestat is under investigation in clinical trial NCT02211079 (A Study to Assess Effect of JNJ-54861911 on Pharmacokinetics of Cocktail Representatives for Cytochrome P450 (CYP) 3A4, CYP2B6, CYP2C9, and CYP1A2 Substrates).
Investigational
Matched Iupac: … N-{3-[(4S)-2-amino-4-methyl-4H-1,3-thiazin-4-yl]-4-fluorophenyl}-5-cyanopyridine-2-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
AVI-7537
AVI-7537 is an antisense molecule that binds to the Ebola virus mRNA to prevent the viral replication. AVI-7537 is under investigation in clinical trial NCT01593072 (A Study to Assess the Safety, Tolerability and Pharmacokinetics of AVI-7537 in Healthy Adult Volunteers).
Investigational
Matched Synonyms: … 5'-GCCATGGTTTTTTCTCAGG-3' …
BB-301
BB-301 is a modified AAV serotype 9 (AAV9) capsid expressing a unique, single bifunctional construct promoting co-expression of both codon-optimized Poly-A Binding Protein Nuclear-1 (PABPN1) and two small inhibitory RNAs (siRNAs) against mutant PABPN1. Developed by Benitec Biopharma, BB-301 is being investigated for the treatment of Oculopharyngeal Muscular Dystrophy (OPMD).
Investigational
Matched Description: … bifunctional construct promoting co-expression of both codon-optimized Poly-A Binding Protein Nuclear-1 …
Etilamfetamine
Etilamfetamine is also known as N-ethylamphetamine and is in the Canadian Legislation - The Controlled Drugs and Substances Act, and is a Schedule 1 controlled drug. Like other amphetamines, this amphetamine analog was used as an appetite suppressant in the 1950s. However, being on the controlled drug and substance act...
Experimental
Matched Iupac: … ethyl(1-phenylpropan-2-yl)amine …
Matched Description: … N-ethylamphetamine and is in the Canadian Legislation - The Controlled Drugs and Substances Act, and is a Schedule 1 …
Matched Description: … N-ethylamphetamine and is in the Canadian Legislation - The Controlled Drugs and Substances Act, and is a Schedule 1 …
L-thioproline
Experimental
Matched Synonyms: … 4-thiaproline ... (4R)-4-Thiazolidinecarboxylic acid ... (R)-4-Thiazolidinecarboxylic acid …
Matched Iupac: … (4R)-1,3-thiazolidine-4-carboxylic acid …
Matched Iupac: … (4R)-1,3-thiazolidine-4-carboxylic acid …
4-Deoxy-4-Amino-Beta-D-Glucose
Experimental
Matched Name: … 4-Deoxy-4-Amino-Beta-D-Glucose …
Matched Iupac: … (2S,3R,4S,5S,6S)-5-amino-6-(hydroxymethyl)oxane-2,3,4-triol …
Matched Iupac: … (2S,3R,4S,5S,6S)-5-amino-6-(hydroxymethyl)oxane-2,3,4-triol …
PYM50018
PYM50018 is a patented, orally active, neuroprotective and neuroregenerative compound. It is developed for the treatment of amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease). In pre-clinical models, PYM50018 has been observed to protect against neuronal damage, increase neurite outgrowth, reverse oxidative damage and reverse neuronal apoptosis in...
Investigational
Naporafenib
Naporafenib is under investigation in clinical trial NCT06346067 (A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With Nras-mutant Melanoma (SEACRAFT-2)).
Investigational
Matched Synonyms: … 4-pyridinecarboxamide, n-(3-(2-(2-hydroxyethoxy)-6-(4-morpholinyl)-4-pyridinyl)-4-methylphenyl)-2-(trifluoromethyl ... N-(3-(2-(hydroxyethoxy)-6-(morpholin-4-yl) pyridin-4-yl)-4-methylphenyl)-2-(trifluoromethyl)pyridine- ... 4-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Furazolidone
A nitrofuran derivative with antiprotozoal and antibacterial activity. Furazolidone binds bacterial DNA which leads to the gradual inhibition of monoamine oxidase. (From Martindale, The Extra Pharmacopoeia, 30th ed, p514)
Experimental
Vet approved
Matched Synonyms: … 3-(5'-Nitrofurfuralamino)-2-oxazolidone ... 3-[(5-Nitrofurylidene)amino]-2-oxazolidone ... 3-[(5-Nitrofurfurylidene)amino]-2-oxazolidone …
Matched Iupac: … 3-[(E)-[(5-nitrofuran-2-yl)methylidene]amino]-1,3-oxazolidin-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 3-[(E)-[(5-nitrofuran-2-yl)methylidene]amino]-1,3-oxazolidin-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
VP025
VP025, a novel drug formulation based on phospholipid microparticles incorporating phosphatidylglycerol, can inhibit neuroinflammation. VP025 may inhibit immune system activation and protect motoneurons from injury. It also shows the ability to reduce inflammation across the blood-brain barrier and improve correlates of memory and learning function. It is being developed to...
Investigational
Guanosine tetraphosphate
Guanosine tetraphosphate is a guanine nucleotide containing four phosphate groups. Two phosphate groups are esterified to the sugar moiety in the 5' position and the other two in the 2' or 3' position. This nucleotide serves as a messenger to turn off the synthesis of ribosomal RNA when amino acids...
Experimental
Matched Synonyms: … Guanosine-5',3'-tetraphosphate …
Matched Iupac: … {[hydroxy({[(2R,3S,4R,5R)-4-hydroxy-3-{[hydroxy(phosphonooxy)phosphoryl]oxy}-5-(6-hydroxy-2-imino-3,9 …
Matched Description: … Two phosphate groups are esterified to the sugar moiety in the 5' position and the other two in the 2 …
Matched Iupac: … {[hydroxy({[(2R,3S,4R,5R)-4-hydroxy-3-{[hydroxy(phosphonooxy)phosphoryl]oxy}-5-(6-hydroxy-2-imino-3,9 …
Matched Description: … Two phosphate groups are esterified to the sugar moiety in the 5' position and the other two in the 2 …
2'-Deoxycytidine 5'-triphosphate
Experimental
Matched Synonyms: … Deoxycytidine 5'-triphosphate ... 2'-Deoxycytidine-5'-Triphosphate …
Matched Name: … 2'-Deoxycytidine 5'-triphosphate …
Matched Iupac: … ({[({[(2R,3S,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Name: … 2'-Deoxycytidine 5'-triphosphate …
Matched Iupac: … ({[({[(2R,3S,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Sevasemten
Sevasemten is under investigation in clinical trial NCT05291091 (Phase 2 Study of EDG-5506 in Becker Muscular Dystrophy (GRAND CANYON)).
Investigational
Matched Synonyms: … 2-[(5-fluoropyridin-3-yl)methyl]-6-[2-(2,2,2- trifluoroethoxy)pyrimidin-5-yl]pyridazin-3(2H)-one …
Displaying drugs 7601 - 7625 of 12049 in total