Displaying drugs 751 - 775 of 2496 in total
Mitoguazone
Mitoguazone has been used in trials studying the treatment of Lymphoma, HIV Infections, and Lymphoma, Non-Hodgkin.
Investigational
Matched Synonyms: … Methyl-G …
Matched Description: … Mitoguazone has been used in trials studying the treatment of Lymphoma, HIV Infections, and Lymphoma, …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Description: … Mitoguazone has been used in trials studying the treatment of Lymphoma, HIV Infections, and Lymphoma, …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Dodecyl creatine ester
Investigational
Matched Synonyms: … Glycine, n-(aminoiminomethyl)-n-methyl-, dodecyl ester …
IM-156 free base
Investigational
Matched Synonyms: … 1-pyrrolidinecarboximidamide, n-(imino((4-(trifluoromethoxy)phenyl)amino)methyl)- ... 1-Pyrrolidinecarboximidamide, N-[imino[[4-(trifluoromethoxy)phenyl]amino]methyl]- ... N-(imino((4-(trifluoromethoxy)phenyl)amino)methyl)-1-pyrrolidinecarboximidamide …
Nalidixic acid
Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase.
Approved
Investigational
Matched Synonyms: … 1-Aethyl-7-methyl-1,8-naphthyridin-4-on-3-karbonsaeure ... 3-carboxy-1-ethyl-7-methyl-1,8-naphthyridin-4-one ... 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid …
Matched Iupac: … 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid …
Matched Description: … Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Iupac: … 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid …
Matched Description: … Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Telmisartan
Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to...
Approved
Investigational
Matched Synonyms: … 4'-((4-methyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimidazolyl)methyl)-2-biphenylcarboxylic acid ... 4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acid ... 4'-[(1,7'-dimethyl-2'-propyl-1H,3'H-2,5'-bibenzimidazol-3'-yl)methyl]biphenyl-2-carboxylic acid …
Matched Iupac: … 4'-{[4-methyl-6-(1-methyl-1H-1,3-benzodiazol-2-yl)-2-propyl-1H-1,3-benzodiazol-1-yl]methyl}-[1,1'-biphenyl …
Matched Mixtures name: … CORDIAX D FORTE COMPRIMIDOS ... SYNTHESIS CORDIAX D ... SYNTHESIS CORDIAX® D COMPRIMIDOS …
Matched Categories: … Antihypertensive Agents Indicated for Hypertension ... telmisartan and diuretics ... telmisartan and amlodipine ... rosuvastatin and telmisartan ... Angiotensin II receptor blockers (ARBs) and diuretics …
Matched Products: … Semintra 4mg/ml Oral Solution for Cats …
Matched Iupac: … 4'-{[4-methyl-6-(1-methyl-1H-1,3-benzodiazol-2-yl)-2-propyl-1H-1,3-benzodiazol-1-yl]methyl}-[1,1'-biphenyl …
Matched Mixtures name: … CORDIAX D FORTE COMPRIMIDOS ... SYNTHESIS CORDIAX D ... SYNTHESIS CORDIAX® D COMPRIMIDOS …
Matched Categories: … Antihypertensive Agents Indicated for Hypertension ... telmisartan and diuretics ... telmisartan and amlodipine ... rosuvastatin and telmisartan ... Angiotensin II receptor blockers (ARBs) and diuretics …
Matched Products: … Semintra 4mg/ml Oral Solution for Cats …
Rimantadine
An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza.
Approved
Investigational
Matched Synonyms: … alpha-Methyl-1-adamantanemethylamine …
Matched Description: … An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza …
Matched Categories: … Antiinfectives for Systemic Use ... Nucleic Acid Synthesis Inhibitors …
Matched Description: … An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza …
Matched Categories: … Antiinfectives for Systemic Use ... Nucleic Acid Synthesis Inhibitors …
2-Methoxy-6-{(E)-[(4-methylphenyl)imino]methyl}phenol
TIMBD is an azaresveratrol analog.
Experimental
Matched Synonyms: … 2-Methoxy-6-[[(4-methylphenyl)imino]methyl]phenol …
Matched Name: … 2-Methoxy-6-{(E)-[(4-methylphenyl)imino]methyl}phenol …
Matched Iupac: … 2-methoxy-6-[(1E)-[(4-methylphenyl)imino]methyl]phenol …
Matched Name: … 2-Methoxy-6-{(E)-[(4-methylphenyl)imino]methyl}phenol …
Matched Iupac: … 2-methoxy-6-[(1E)-[(4-methylphenyl)imino]methyl]phenol …
6-fluoro-9-methyl-9H-pyrido(3,4-B)-indole
Investigational
Matched Synonyms: … 6-fluoro-9-methyl-9H-pyrido[3,4-b]-indole …
Matched Name: … 6-fluoro-9-methyl-9H-pyrido(3,4-B)-indole …
Matched Iupac: … 6-fluoro-9-methyl-9H-pyrido[3,4-b]indole …
Matched Name: … 6-fluoro-9-methyl-9H-pyrido(3,4-B)-indole …
Matched Iupac: … 6-fluoro-9-methyl-9H-pyrido[3,4-b]indole …
Succinylcholine
Succinylcholine is a depolarizing skeletal muscle relaxant consisting of two molecules of the endogenous neurotransmitter acetylcholine (ACh) linked by their acetyl groups. It has been widely used for over 50 years, most commonly in its chloride salt form, as a means of neuromuscular blockade during intubation and surgical procedures. Its...
Approved
Matched Description: … Its rapid onset and offset, with effects beginning within 60 seconds of intravenous administration and ... [A19054] It has been widely used for over 50 years,[A299] most commonly in its chloride salt form, as ... a means of neuromuscular blockade during intubation and surgical procedures. …
Matched Products: … LYSTHENON FORTE %2 ENJEKSİYONLUK ÇÖZELTİ, 25 AMPUL ... Pharmaniaga Suxamethonium Chloride 100mg/2ml Solution for Injection ... MARTINDALE PHARMA SUXAMETHONIUM CHLORIDE SOLUTION FOR INJECTION 50MG/ML …
Matched Products: … LYSTHENON FORTE %2 ENJEKSİYONLUK ÇÖZELTİ, 25 AMPUL ... Pharmaniaga Suxamethonium Chloride 100mg/2ml Solution for Injection ... MARTINDALE PHARMA SUXAMETHONIUM CHLORIDE SOLUTION FOR INJECTION 50MG/ML …
RU84687
RU84687 is a subnanomolar and Src SH2 selective binder.
Experimental
Matched Synonyms: … N-acetyl-N-[1-(1,1'-biphenyl-4-ylmethyl)-2-oxoazepan-3-yl]-3-formyl-O-phosphonotyrosinamide …
Matched Iupac: … {4-[(2S)-2-{[(3S)-1-({[1,1'-biphenyl]-4-yl}methyl)-2-oxoazepan-3-yl]carbamoyl}-2-acetamidoethyl]-2-formylphenoxy …
Matched Description: … RU84687 is a subnanomolar and Src SH2 selective binder. …
Matched Iupac: … {4-[(2S)-2-{[(3S)-1-({[1,1'-biphenyl]-4-yl}methyl)-2-oxoazepan-3-yl]carbamoyl}-2-acetamidoethyl]-2-formylphenoxy …
Matched Description: … RU84687 is a subnanomolar and Src SH2 selective binder. …
(R)-Fluoxetine
An N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine that has R configuration (the antidepressant drug fluoxetine is a racemate comprising equimolar amounts of (R)- and (S)-fluoxetine).
Experimental
Matched Synonyms: … (R)-N-methyl-3-(4-trifluoromethylphenoxy)-3-phenylpropylamine ... (R)-N-methyl-γ-(4-trifluoromethylphenoxy)-3-phenylpropylamine ... (R)-N-methyl-3-(4-trifluoromethylphenyloxy)-3-(phenyl)propylamine …
Matched Iupac: … methyl[(3R)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]amine …
Matched Description: … drug fluoxetine is a racemate comprising equimolar amounts of (R)- and (S)-fluoxetine). ... An N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine that has R configuration (the antidepressant …
Matched Iupac: … methyl[(3R)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]amine …
Matched Description: … drug fluoxetine is a racemate comprising equimolar amounts of (R)- and (S)-fluoxetine). ... An N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine that has R configuration (the antidepressant …
Calmangafodipir
Investigational
Matched Synonyms: … Calcium,n,n'-1,2-ethanediylbis(n-((3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinyl)methyl)glycine …
Matched Iupac: … ]-3-hydroxy-2-methylpyridin-4-yl}methyl)amino]ethyl})amino]methyl}-5-hydroxy-6-methylpyridin-3-yl)methyl ... tetracalcium manganese(2+) pentakis((4-{[(carboxymethyl)({2-[(carboxymethyl)({5-[(hydrogen phosphonatooxy)methyl …
Matched Categories: … Enzymes and Coenzymes …
Matched Iupac: … ]-3-hydroxy-2-methylpyridin-4-yl}methyl)amino]ethyl})amino]methyl}-5-hydroxy-6-methylpyridin-3-yl)methyl ... tetracalcium manganese(2+) pentakis((4-{[(carboxymethyl)({2-[(carboxymethyl)({5-[(hydrogen phosphonatooxy)methyl …
Matched Categories: … Enzymes and Coenzymes …
Thioridazine
A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the control of severely disturbed or agitated behavior. It has little antiemetic activity. Thioridazine has a higher incidence of antimuscarinic effects, but a lower incidence of extrapyramidal symptoms, than chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed,...
Approved
Withdrawn
Matched Synonyms: … 10-[2-(1-methyl-2-piperidyl)ethyl]-2-methylsulfanyl-phenothiazine ... 2-Methylmercapto-10-(2-(N-methyl-2-piperidyl)ethyl)phenothiazine ... 3-Methylmercapto-N-(2'-(N-methyl-2-piperidyl)ethyl)phenothiazine …
Matched Description: … A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the …
Matched Description: … A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the …
Profadol
Investigational
Matched Synonyms: … M-(1-methyl-3-propyl-3-pyrrolidinyl)phenol ... Phenol, 3-(1-methyl-3-propyl-3-pyrrolidinyl)- ... Phenol, m-(1-methyl-3-propyl-3-pyrrolidinyl)- …
Matched Iupac: … 3-(1-methyl-3-propylpyrrolidin-3-yl)phenol …
Matched Iupac: … 3-(1-methyl-3-propylpyrrolidin-3-yl)phenol …
Methylchloroisothiazolinone
Methylchloroisothiazolinone (MCI) is an isothiazolinone commonly used as a preservative with antibacterial and antifungal properties. It is found within many commercially available cosmetics, lotions, and makeup removers. It is also a known dermatological sensitizer and allergen; some of its side effects include flaky or scaly skin, breakouts, redness or itchiness,...
Approved
Experimental
Matched Synonyms: … 5-Chloro-2-methyl-3(2H)-isothiazolone ... 4-Isothiazolin-3-one, 5-chloro-2-methyl- …
Matched Iupac: … 5-chloro-2-methyl-2,3-dihydro-1,2-thiazol-3-one …
Matched Description: … American Contact Dermatitis Society named Methylchloroisothiazolinone the Contact Allergen of the Year for ... It is found within many commercially available cosmetics, lotions, and makeup removers. ... scaly skin, breakouts, redness or itchiness, and moderate to severe swelling in the eye area. …
Matched Iupac: … 5-chloro-2-methyl-2,3-dihydro-1,2-thiazol-3-one …
Matched Description: … American Contact Dermatitis Society named Methylchloroisothiazolinone the Contact Allergen of the Year for ... It is found within many commercially available cosmetics, lotions, and makeup removers. ... scaly skin, breakouts, redness or itchiness, and moderate to severe swelling in the eye area. …
(2R)-3-[(tetrahydroxyphosphoranyl)oxy]-1,2-propanediyl dibutanoate
Experimental
Matched Synonyms: … 2-(butyryloxy)-1-{[(tetrahydroxyphosphoranyl)oxy]methyl}ethyl butyrate …
Indatraline
Indatraline is a nonselective monoamine reuptake inhibitor.
Investigational
Matched Synonyms: … (+/-)-trans-3-(3,4-dichlorophenyl)-n-methyl-1-indanamine …
Matched Iupac: … (1R,3S)-3-(3,4-dichlorophenyl)-N-methyl-2,3-dihydro-1H-inden-1-amine …
Matched Iupac: … (1R,3S)-3-(3,4-dichlorophenyl)-N-methyl-2,3-dihydro-1H-inden-1-amine …
2-Methoxyestradiol
2-Methoxyestradiol (2ME2) is a drug that prevents the formation of new blood vessels that tumors need in order to grow (angiogenesis). It has undergone Phase 1 clinical trials against breast cancers and preclinical studies suggest that 2ME2 could also be effective against inflammatory diseases such as rheumatoid arthritis.
Investigational
Matched Synonyms: … 2-Hydroxyestradiol 2-methyl ether ... 2-Hydroxyestradol 2-methyl ether …
Matched Iupac: … (1S,3aS,3bR,9bS,11aS)-8-methoxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene …
Matched Description: … It has undergone Phase 1 clinical trials against breast cancers and preclinical studies suggest that …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Iupac: … (1S,3aS,3bR,9bS,11aS)-8-methoxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene …
Matched Description: … It has undergone Phase 1 clinical trials against breast cancers and preclinical studies suggest that …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Thenalidine
Withdrawn from the Canadian, US, and UK markets in 1963 due to concerns involving neutropenia.
Approved
Withdrawn
Matched Synonyms: … 1-Methyl-4-N-2-thenylanilinopiperidine ... 1-Methyl-4-amino-N-phenyl-N-(2-thenyl)piperidine …
Matched Iupac: … 1-methyl-N-phenyl-N-[(thiophen-2-yl)methyl]piperidin-4-amine …
Matched Description: … Withdrawn from the Canadian, US, and UK markets in 1963 due to concerns involving neutropenia. …
Matched Categories: … Antihistamines for Systemic Use ... Antihistamines for Topical Use …
Matched Iupac: … 1-methyl-N-phenyl-N-[(thiophen-2-yl)methyl]piperidin-4-amine …
Matched Description: … Withdrawn from the Canadian, US, and UK markets in 1963 due to concerns involving neutropenia. …
Matched Categories: … Antihistamines for Systemic Use ... Antihistamines for Topical Use …
Flubendazole
Flubendazole is an anthelmintic that is used to treat worm infection in humans. It is available OTC in Europe.
Experimental
Withdrawn
Matched Synonyms: … methyl 5-(p-fluorobenzoyl)-2-benzimidazolecarbamate ... (5-(4-fluorobenzoyl)-1H-benzimidazole-2-yl)carbamic acid methyl ester …
Matched Iupac: … methyl N-[5-(4-fluorobenzoyl)-1H-1,3-benzodiazol-2-yl]carbamate …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Matched Iupac: … methyl N-[5-(4-fluorobenzoyl)-1H-1,3-benzodiazol-2-yl]carbamate …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Defactinib
Defactinib has been investigated for the treatment of Malignant Pleural Mesothelioma.
Investigational
Matched Synonyms: … N-methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin …
Matched Iupac: … N-methyl-4-{[4-({[3-(N-methylmethanesulfonamido)pyrazin-2-yl]methyl}amino)-5-(trifluoromethyl)pyrimidin …
Matched Description: … Defactinib has been investigated for the treatment of Malignant Pleural Mesothelioma. …
Matched Iupac: … N-methyl-4-{[4-({[3-(N-methylmethanesulfonamido)pyrazin-2-yl]methyl}amino)-5-(trifluoromethyl)pyrimidin …
Matched Description: … Defactinib has been investigated for the treatment of Malignant Pleural Mesothelioma. …
Secnidazole
Secnidazole is a second-generation 5-nitroimidazole antimicrobial agent. It is structurally related to other 5-nitroimidazoles, including DB00916 and DB00911, but displays improved oral absorption and a longer terminal elimination half-life than other drugs in this class. Secnidazole is selective against many anaerobic Gram-positive and Gram-negative bacteria as well as protozoa. Once...
Approved
Matched Synonyms: … 1-(2 hydroxypropyl)-2-methyl-5-nitroimidazole ... 1-(2-methyl-5-nitro-1H-imidazol-1-yl) propan-2 ol …
Matched Iupac: … 1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol …
Matched Description: … to form a radical anion, thereby damaging and killing the target pathogen. ... Africa for decades. ... treatment of trichomoniasis and bacterial vaginosis. …
Matched Categories: … azithromycin, fluconazole and secnidazole ... Antiparasitic Products, Insecticides and Repellents ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Iupac: … 1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol …
Matched Description: … to form a radical anion, thereby damaging and killing the target pathogen. ... Africa for decades. ... treatment of trichomoniasis and bacterial vaginosis. …
Matched Categories: … azithromycin, fluconazole and secnidazole ... Antiparasitic Products, Insecticides and Repellents ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Alogabat
Investigational
Matched Synonyms: … 3-pyridazinecarboxamide, 6-((5-methyl-3-(6-methyl-3-pyridinyl)-4-isoxazolyl)methoxy)-n-(tetrahydro-2h-pyran …
Matched Iupac: … 6-{[5-methyl-3-(6-methylpyridin-3-yl)-1,2-oxazol-4-yl]methoxy}-N-(oxan-4-yl)pyridazine-3-carboxamide …
Matched Iupac: … 6-{[5-methyl-3-(6-methylpyridin-3-yl)-1,2-oxazol-4-yl]methoxy}-N-(oxan-4-yl)pyridazine-3-carboxamide …
Elimusertib
Elimusertib is under investigation in clinical trial NCT05071209 (Elimusertib for the Treatment of Relapsed or Refractory Solid Tumors).
Investigational
Matched Synonyms: … 1,7-naphthyridine, 2-((3r)-3-methyl-4-morpholinyl)-4-(1-methyl-1h-pyrazol-5-yl)-8-(1h-pyrazol-3-yl)- …
Matched Description: … Elimusertib is under investigation in clinical trial NCT05071209 (Elimusertib for the Treatment of Relapsed …
Matched Description: … Elimusertib is under investigation in clinical trial NCT05071209 (Elimusertib for the Treatment of Relapsed …
Reserpine
An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool,...
Approved
Investigational
Withdrawn
Matched Synonyms: … 3,4,5-trimethoxybenzoyl methyl reserpate ... 17alpha,18beta,20alpha)-11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid methyl …
Matched Iupac: … methyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-(3,4,5-trimethoxybenzoyloxy)-3,13-diazapentacyclo[11.8.0.0 …
Matched Description: … The FDA withdrew its approval for the use of all oral dosage form drug products containing more than ... serotonin from central and peripheral axon terminals. ... An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. …
Matched Categories: … Antihypertensive Agents Indicated for Hypertension ... reserpine and diuretics ... reserpine and diuretics, combinations with other drugs ... reserpine and diuretics, combinations with psycholeptics …
Matched Iupac: … methyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-(3,4,5-trimethoxybenzoyloxy)-3,13-diazapentacyclo[11.8.0.0 …
Matched Description: … The FDA withdrew its approval for the use of all oral dosage form drug products containing more than ... serotonin from central and peripheral axon terminals. ... An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. …
Matched Categories: … Antihypertensive Agents Indicated for Hypertension ... reserpine and diuretics ... reserpine and diuretics, combinations with other drugs ... reserpine and diuretics, combinations with psycholeptics …
Displaying drugs 751 - 775 of 2496 in total