Displaying drugs 751 - 775 of 1297 in total
Lirentelimab
Lirentelimab is under investigation in clinical trial NCT04856891 (A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Duodenitis).
Investigational
Matched Synonyms: … MONOCLONAL ANTIBODY AK002 ... IMMUNOGLOBULIN G1, ANTI-(HUMAN SIALIC ACID-BINDINGE IG-LIKE LECTIN 8) (HUMAN-MUS MUSCULUS MONOCLONAL ... Recombinant humanized, non-fucosylated IgG1 anti-Siglec-8 monoclonal antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Bevacizumab
There is a great deal of evidence indicating that vascular endothelial growth factor (VEGF) is important for the survival and proliferation of cancer cells.[A192939,A192837,A192891,A193275] VEGF plays an important role in angiogenesis, lymphangiogenesis, and tumor growth, which are all factors that contribute to its attractiveness as a therapeutic target for anti-cancer...
Approved
Investigational
Matched Synonyms: … Anti-VEGF monoclonal antibody ... Anti-VEGF Humanized Monoclonal Antibody …
Matched Description: … [A193272,A193275] It is a humanized monoclonal IgG antibody, and inhibits angiogenesis by binding and ... of evidence indicating that vascular endothelial growth factor (VEGF) is important for the survival and ... [A192939,A192837,A192891,A193275] VEGF plays an important role in angiogenesis, lymphangiogenesis, and …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Vascular Endothelial Growth Factor-directed Antibody Interactions …
Matched Description: … [A193272,A193275] It is a humanized monoclonal IgG antibody, and inhibits angiogenesis by binding and ... of evidence indicating that vascular endothelial growth factor (VEGF) is important for the survival and ... [A192939,A192837,A192891,A193275] VEGF plays an important role in angiogenesis, lymphangiogenesis, and …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Vascular Endothelial Growth Factor-directed Antibody Interactions …
2G7
2G7 is an anti-TGF-beta monoclonal antibody developed by Genentech.
Investigational
Matched Synonyms: … Anti-TGF-beta antibody 2G7 ... Anti-TGF-beta monoclonal antibody 2G7 ... Anti-transforming growth factor-beta monoclonal antibody 2G7 …
Matched Description: … 2G7 is an anti-TGF-beta monoclonal antibody developed by Genentech. …
Matched Description: … 2G7 is an anti-TGF-beta monoclonal antibody developed by Genentech. …
Ammonium tetrathiomolybdate
Investigational
Matched Synonyms: … Ammonium molybdenum sulfide ((nh4)2mos4) …
Matched Iupac: … diammonium (sulfanidyldisulfanylidenemolybdenio)sulfanide …
Matched Iupac: … diammonium (sulfanidyldisulfanylidenemolybdenio)sulfanide …
Human Lactoferrin Peptide hLF1-11
Human Lactoferrin Peptide hLF1-11 is under investigation in clinical trial NCT00509834 (A Study on the Tolerability and Early Efficacy of Hlf1-11 in Patients With Proven Candidaemia).
Investigational
Matched Synonyms: … Human lactoferrin 1-11 ... N-terminal peptide of human lactoferrin 1-11 …
Matched Name: … Human Lactoferrin Peptide hLF1-11 …
Matched Description: … Tolerability and Early Efficacy of Hlf1-11 in Patients With Proven Candidaemia). ... Human Lactoferrin Peptide hLF1-11 is under investigation in clinical trial NCT00509834 (A Study on the …
Matched Name: … Human Lactoferrin Peptide hLF1-11 …
Matched Description: … Tolerability and Early Efficacy of Hlf1-11 in Patients With Proven Candidaemia). ... Human Lactoferrin Peptide hLF1-11 is under investigation in clinical trial NCT00509834 (A Study on the …
Gentian violet cation
A dye that is a mixture of violet rosanilinis with antibacterial, antifungal, and anthelmintic properties.
Approved
Matched Description: … A dye that is a mixture of violet rosanilinis with antibacterial, antifungal, and anthelmintic properties …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Humco Gentian Violet 2% ... Humco Gentian Violet 1% …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Humco Gentian Violet 2% ... Humco Gentian Violet 1% …
Idursulfase
Idursulfase is a purified form of human iduronate-2-sulfatase, a lysosomal enzyme. Idursulfase is produced by recombinant DNA technology in a human cell line. Idursulfase is an enzyme that hydrolyzes the 2-sulfate esters of terminal iduronate sulfate residues from the glycosaminoglycans dermatan sulfate and heparan sulfate in the lysosomes of various...
Approved
Matched Synonyms: … Alpha-L-iduronate sulfate sulfatase …
Matched Description: … from the glycosaminoglycans dermatan sulfate and heparan sulfate in the lysosomes of various cell types ... Idursulfase is produced by recombinant DNA technology in a human cell line. ... Idursulfase is a purified form of human iduronate-2-sulfatase, a lysosomal enzyme. …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Description: … from the glycosaminoglycans dermatan sulfate and heparan sulfate in the lysosomes of various cell types ... Idursulfase is produced by recombinant DNA technology in a human cell line. ... Idursulfase is a purified form of human iduronate-2-sulfatase, a lysosomal enzyme. …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Amphetamine
Amphetamine, a compound discovered over 100 years ago, is one of the more restricted controlled drugs. It was previously used for a large variety of conditions and this changed until this point where its use is highly restricted. Amphetamine, with the chemical formula alpha-methylphenethylamine, was discovered in 1910 and first...
Approved
Illicit
Investigational
Matched Description: … After being proven to reduce drug-induced anesthesia and produce arousal and insomnia, amphetamine racemic ... Amphetamine structure presents one chiral center and it exists in the form of dextro- and levo-isomers ... mix was registered by Smith, Kline and French in 1935. …
Matched Mixtures name: … Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, and Amphetamine Sulfate ... Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, and Amphetamine Sulfate ... Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, and Amphetamine Sulfate …
Matched Salts name: … Amphetamine sulfate …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … Amphetamine Sulfate ... Amphetamine sulfate …
Matched Mixtures name: … Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, and Amphetamine Sulfate ... Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, and Amphetamine Sulfate ... Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, and Amphetamine Sulfate …
Matched Salts name: … Amphetamine sulfate …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … Amphetamine Sulfate ... Amphetamine sulfate …
Ongericimab
Ongericimab is under investigation in clinical trial NCT05325203 (A Study to Evaluate the Efficacy and Safety of JS002 in Patients With Heterozygous Familial Hypercholesterolemia (Hefh).).
Investigational
Matched Synonyms: … ), disulfide with human monoclonal js002 .kappa. ... apoptosis-regulated convertase 1, narc1, narc-1, proprotein convertase 9, pc9)), humanized monoclonal antibody ... Immunoglobulin g4, anti-(neural apoptosis-regulated convertase 1) (human monoclonal js002 .gamma.4-chain …
Matched Description: … Ongericimab is under investigation in clinical trial NCT05325203 (A Study to Evaluate the Efficacy and …
Matched Description: … Ongericimab is under investigation in clinical trial NCT05325203 (A Study to Evaluate the Efficacy and …
Human vaccinia virus immune globulin
Human vaccinia immune globulin (VIG) is a sterile solution containing the purified gamma globulin (IgG) fraction of plasma taken from healthy donors previously vaccinated with live vaccinia virus vaccine who possess high titers of anti-vaccinia virus antibody [FDA Label, A33814]. The IgG fraction is purified by the anion-exchange column chromatography...
Approved
Matched Synonyms: … Human vaccinia immune globulin ... Vaccinia Immune Globulin (Human) Intravenous ... Vaccinia immune globulin intravenous (human) …
Matched Name: … Human vaccinia virus immune globulin …
Matched Description: … Nevertheless, VIG by virtue of the way it is produced is a poorly characterized and highly variable human ... The IgG fraction is purified by the anion-exchange column chromatography method and the solution is solvent ... is only available in very limited quantities - all factors that may intervene with its availability and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Human Immunoglobulin G …
Matched Name: … Human vaccinia virus immune globulin …
Matched Description: … Nevertheless, VIG by virtue of the way it is produced is a poorly characterized and highly variable human ... The IgG fraction is purified by the anion-exchange column chromatography method and the solution is solvent ... is only available in very limited quantities - all factors that may intervene with its availability and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Human Immunoglobulin G …
Iratumumab
Immunoglobulin G1, anti-(human CD30 (antigen)) (human monoclonal MDX-060 heavy chain), disulfide with human monoclonal MDX-060 light chain, dimer. Molecular weight is approximately 170,000 daltons. In phase I/II clinical trials for treatment of CD30+ lymphomas.
Investigational
Matched Synonyms: … 5F11 monoclonal antibody …
Matched Description: … Immunoglobulin G1, anti-(human CD30 (antigen)) (human monoclonal MDX-060 heavy chain), disulfide with ... human monoclonal MDX-060 light chain, dimer. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Immunoglobulin G1, anti-(human CD30 (antigen)) (human monoclonal MDX-060 heavy chain), disulfide with ... human monoclonal MDX-060 light chain, dimer. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Cefuroxime
Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Approved
Matched Description: … It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus …
Matched Categories: … cefuroxime and metronidazole …
Matched Products: … Cefuroxime and Dextrose …
Matched Categories: … cefuroxime and metronidazole …
Matched Products: … Cefuroxime and Dextrose …
Mezagitamab
Mezagitamab is under investigation in clinical trial NCT04278924 (Study to Evaluate Safety, Tolerability, and Efficacy of TAK-079 in Participants With Persistent/chronic Primary Immune Thrombocytopenia).
Investigational
Matched Synonyms: … Anti-Cd38 monoclonal antibody TAK-079 ... IMMUNOGLOBULIN G1, ANTI-(HUMAN CD38 ANTIGEN) (HUMAN MONOCLONAL AB79 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN …
Matched Description: … Mezagitamab is under investigation in clinical trial NCT04278924 (Study to Evaluate Safety, Tolerability, and …
Matched Description: … Mezagitamab is under investigation in clinical trial NCT04278924 (Study to Evaluate Safety, Tolerability, and …
humanized SMART Anti-IL-12 Antibody
The humanized anti-IL-12 antibody is an important addition to PDL's already strong pipeline of humanized antibodies being developed for the treatment of autoimmune diseases. SMART Anti-IL-12 Antibody was humanized at PDL from a murine anti-IL-12 antibody that was licensed, together with certain intellectual property related to anti-IL-12 therapy, from Hoffmann-La...
Investigational
Matched Name: … humanized SMART Anti-IL-12 Antibody …
Matched Description: … SMART Anti-IL-12 Antibody was humanized at PDL from a murine anti-IL-12 antibody that was licensed, together ... The humanized anti-IL-12 antibody is an important addition to PDL's already strong pipeline of humanized …
Matched Description: … SMART Anti-IL-12 Antibody was humanized at PDL from a murine anti-IL-12 antibody that was licensed, together ... The humanized anti-IL-12 antibody is an important addition to PDL's already strong pipeline of humanized …
Bertilimumab
Bertilimumab is a fully human anti-eotaxin monoclonal antibody with potential in the treatment of allergic disorders, has moved into pre-clinical development. It is developed by MedImmune for the treatment of Allergic Rhinitis.
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4, ANTI-(HUMAN EOTAXIN 1) (HUMAN MONOCLONAL CAT-213 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN …
Matched Description: … Bertilimumab is a fully human anti-eotaxin monoclonal antibody with potential in the treatment of allergic …
Matched Description: … Bertilimumab is a fully human anti-eotaxin monoclonal antibody with potential in the treatment of allergic …
Nipocalimab
Nipocalimab is under investigation in clinical trial NCT04119050 (Efficacy and Safety of M281 in Adults With Warm Autoimmune Hemolytic Anemia).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human neonatal fc receptor) (human monoclonal m281 .gamma.-1 chain), disulfide ... with human monoclonal m281 .lambda. …
Matched Description: … Nipocalimab is under investigation in clinical trial NCT04119050 (Efficacy and Safety of M281 in Adults …
Matched Description: … Nipocalimab is under investigation in clinical trial NCT04119050 (Efficacy and Safety of M281 in Adults …
Remestemcel-L
Remestemcel-L is a third-party, off-the-shelf suspension of ex-vivo cultured adult human mesenchymal stem cells intended for intravenous infusion. The mesenchymal stem cells are derived from the bone marrow of unrelated and human leukocyte antigen (HLA)–unmatched healthy adult donors and have the ability to differentiate into different tissue cells. It was...
Approved
Investigational
Matched Synonyms: … Adult human mesenchymal stem cells ... Allogeneic human mesenchymal stem cell …
Matched Description: … The mesenchymal stem cells are derived from the bone marrow of unrelated and human leukocyte antigen ... Human mesenchymal stem cells (hMSCs) serve to down-regulate inflammatory responses and produce anti-inflammatory ... cytokines and growth factors to promote tissue repair [A31818]. …
Matched Description: … The mesenchymal stem cells are derived from the bone marrow of unrelated and human leukocyte antigen ... Human mesenchymal stem cells (hMSCs) serve to down-regulate inflammatory responses and produce anti-inflammatory ... cytokines and growth factors to promote tissue repair [A31818]. …
Endothelin-1
Endothelin 1 is under investigation in clinical trial NCT00745693 (The Effects of Diesel Exhaust Inhalation on Vascular Function - the Role of Endothelin).
Investigational
Matched Synonyms: … Human endothelin ... Endothelin 1 (human) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Atibuclimab
Atibuclimab (IC14) is a chimeric CD14 antibody investigated for the treatment of patients with severe sepsis.
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4, ANTI-(HUMAN CD14 ANTIGEN) (HUMAN-MUS MUSCULUS MONOCLONAL IC14 .GAMMA.4-CHAIN), DISULFIDE ... IC14, (RECOMBINANT CHIMERIC MAB AGAINST HUMAN CD14) ... WITH HUMAN-MUS MUSCULUS MONOCLONAL IC14 .KAPPA. …
Matched Description: … Atibuclimab (IC14) is a chimeric CD14 antibody investigated for the treatment of patients with severe …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Atibuclimab (IC14) is a chimeric CD14 antibody investigated for the treatment of patients with severe …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Hepatitis C immune globulin (human)
Investigational
Matched Synonyms: … Hepatitis C immune globulin (human) ... Hepatitis C human polyclonal immune globulin ... Hepatitis C virus immune globulin (human) …
Matched Name: … Hepatitis C immune globulin (human) …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Name: … Hepatitis C immune globulin (human) …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Elotuzumab
Elotuzumab is a humanized IgG1 (Immunoglobulin G) monoclonal antibody indicated in combination with lenalidomide and dexamethasone for the treatment of patients with multiple myeloma who have received one to three prior therapies. Elotuzumab targets SLAMF7, also known as Signaling Lymphocytic Activation Molecule Family member 7, a cell surface glycoprotein. Elotuzumab...
Approved
Matched Synonyms: … Immunoglobulin G1, anti-(human protein CS1) (human-mouse HuLuc63 heavy chain), disulfide with human-mouse …
Matched Description: … onto human IgG1 heavy and kappa light chain frameworks. ... Food and Drug Administration. ... and dexamethasone for the treatment of patients with multiple myeloma who have received one to three …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... SLAMF7-directed Antibody Interactions ... SLAMF7-directed Immunostimulatory Antibody …
Matched Description: … onto human IgG1 heavy and kappa light chain frameworks. ... Food and Drug Administration. ... and dexamethasone for the treatment of patients with multiple myeloma who have received one to three …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... SLAMF7-directed Antibody Interactions ... SLAMF7-directed Immunostimulatory Antibody …
Garadacimab
Garadacimab is under investigation in clinical trial NCT04281524 (A Clinical Study to Test the Efficacy and Safety of CSL312 on Catheter-associated Blood Clot Formation in Subjects With Cancer Who Receive Chemotherapy Through a PICC Line).
Investigational
Matched Synonyms: … Immunoglobulin G4, anti-(human blood-coagulation factor viia) (human monoclonal CSL312 gamma4-chain), ... disulfide with human monoclonal CSL312 lambda-chain, dimer …
Matched Description: … Garadacimab is under investigation in clinical trial NCT04281524 (A Clinical Study to Test the Efficacy and …
Matched Description: … Garadacimab is under investigation in clinical trial NCT04281524 (A Clinical Study to Test the Efficacy and …
Socazolimab
Socazolimab is under investigation in clinical trial NCT04878016 (A Study of Carboplatin Plus Etoposide With or Without ZKAB001 (Anti-pd-l1 Antibody) in Patients With ES-SCLC).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human programmed death-ligand 1) (human monoclonal zkab001 .gamma.1-chain), ... disulfide with human monoclonal zkab001 .lambda. …
Matched Description: … clinical trial NCT04878016 (A Study of Carboplatin Plus Etoposide With or Without ZKAB001 (Anti-pd-l1 Antibody …
Matched Description: … clinical trial NCT04878016 (A Study of Carboplatin Plus Etoposide With or Without ZKAB001 (Anti-pd-l1 Antibody …
Ginisortamab
Ginisortamab is under investigation in clinical trial NCT04393298 (A Study to Assess the Safety, Pharmacokinetics and Anti Tumor Activity of UCB6114 Administered Intravenously to Participants With Advanced Solid Tumors).
Investigational
Matched Synonyms: … Immunoglobulin g4 (232-proline), anti-(human gremlin 1) (human monoclonal ucb6114 .gamma.4-chain), disulfide ... with human monoclonal ucb6114 .kappa. …
Matched Description: … is under investigation in clinical trial NCT04393298 (A Study to Assess the Safety, Pharmacokinetics and …
Matched Description: … is under investigation in clinical trial NCT04393298 (A Study to Assess the Safety, Pharmacokinetics and …
Sibeprenlimab
Sibeprenlimab is under investigation in clinical trial NCT05248659 (Phase 2/3 Open-label Trial of Sibeprenlimab in the Treatment of Immunoglobulin a Nephropathy).
Investigational
Matched Synonyms: … Immunoglobulin g2, anti-(human proliferation-inducing ligand protein) (human monoclonal vis649 .gamma ... .2-chain), disulfide with human monoclonal vis649 .kappa. …
Displaying drugs 751 - 775 of 1297 in total