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Displaying drugs 776 - 800 of 5758 in total
Sodium Lauryl Sulfate (SLS) is an anionic surfactant naturally derived from coconut and/or palm kernel oil. It usually consists of a mixture of sodium alkyl sulfates, mainly the lauryl. SLS lowers surface tension of aqueous solutions and is used as fat emulsifier, wetting agent, and detergent in cosmetics, pharmaceuticals and...
Experimental
Matched Synonyms: … Sodium laurilsulfate ... Sodium dodecyl sulfate ... Sodium dodecylsulfate …
Matched Name: … Sodium lauryl sulfate …
Matched Iupac: … sodium dodecyl sulfate …
Matched Description: … Sodium Lauryl Sulfate (SLS) is an anionic surfactant naturally derived from coconut and/or palm kernel ... SLS lowers surface tension of aqueous solutions and is used as fat emulsifier, wetting agent, and detergent ... It is also used in creams and pastes to properly disperse the ingredients and as research tool in protein …
Experimental
Matched Name: … 1-(5-Tert-Butyl-2-Methyl-2h-Pyrazol-3-Yl)-3-(4-Chloro-Phenyl)-Urea …
Matched Iupac: … 3-(3-tert-butyl-1-methyl-1H-pyrazol-5-yl)-1-(4-chlorophenyl)urea …
Bisoprolol is a cardioselective β1-adrenergic blocking agent used to treat high blood pressure.[A180472,L7219] It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs. Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor...
Approved
Matched Synonyms: … (RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol ... (+-)-1-((alpha-(2-Isopropoxyethoxy)-p-tolyl)oxy)-3-(isopropylamino)-2-propanol …
Matched Iupac: … 1-[(propan-2-yl)amino]-3-(4-{[2-(propan-2-yloxy)ethoxy]methyl}phenoxy)propan-2-ol …
Matched Description: … A180472] Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor selectivity and ... alternative to non-selective β-blocker drugs in the treatment of hypertension such as [Carvedilol] and ... It may be used alone or in combination with other drugs to manage hypertension[L7219] and can be useful …
Matched Mixtures name: … BISOPROLOL DURA P10/25MG ... BISOPROLOL DURA P10/25MG ... BISOPROLOL DURA P10/25MG …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates ... Beta Blocking Agents and Thiazides ... P-glycoprotein inhibitors …
Matched Products: … PMS-bisoprolol ... PHL-bisoprolol ... Prz-bisoprolol …
DMP-777 is a selective inhibitor of polymorphonuclear leukocyte (PMN) elastase.
Investigational
Matched Synonyms: … 1-AZETIDINECARBOXAMIDE, N-((1R)-1-(1,3-BENZODIOXOL-5-YL)BUTYL)-3,3-DIETHYL-2-(4-((4-METHYL-1-PIPERAZINYL ... )CARBONYL)PHENOXY)-4-OXO-, (2S)- …
Matched Iupac: … (2S)-N-[(1R)-1-(2H-1,3-benzodioxol-5-yl)butyl]-3,3-diethyl-2-[4-(4-methylpiperazine-1-carbonyl)phenoxy ... ]-4-oxoazetidine-1-carboxamide …
Matched Description: … DMP-777 is a selective inhibitor of polymorphonuclear leukocyte (PMN) elastase. …
Ethotoin is a hydantoin derivative and anticonvulsant. Ethotoin exerts an antiepileptic effect without causing general central nervous system depression. The mechanism of action is probably very similar to that of phenytoin. The latter drug appears to stabilize rather than to raise the normal seizure threshold, and to prevent the spread...
Approved
Matched Synonyms: … 1-ethyl-2,5-dioxo-4-phenylimidazolidine ... 3-ethyl-5-phenyl-2,4-imidazolidinedione ... 3-Ethyl-5-phenyl-imidazolidine-2,4-dione …
Matched Iupac: … 3-ethyl-5-phenylimidazolidine-2,4-dione …
Matched Description: … Ethotoin is a hydantoin derivative and anticonvulsant. ... The latter drug appears to stabilize rather than to raise the normal seizure threshold, and to prevent …
Matched Categories: … Cytochrome P-450 CYP3A Inducers ... Cytochrome P-450 CYP3A4 Inducers ... Cytochrome P-450 Enzyme Inducers ... Sodium Channel Blockers ... Voltage-Gated Sodium Channel Blockers …
Peldesine is a potent inhibitor of human CCRF-CEM T-cell proliferation. It has undergone phase I trials for the treatment of Human Immunodeficiency Virus (HIV) infections.
Investigational
Matched Synonyms: … 2-Amino-3,5-dihydro-7-(3-pyridylmethyl)-4H-pyrrolo(3,2-d)pyrimidin-4-one …
Matched Iupac: … 2-amino-7-[(pyridin-3-yl)methyl]-1H,4H,5H-pyrrolo[3,2-d]pyrimidin-4-one …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates …
Sinapic acid is a matrix for matrix-assisted laser desorption technique for protein MW determination. It is also a constituent of propolis.
Experimental
Matched Synonyms: … (E)-3-(4-Hydroxy-3,5-dimethoxyphenyl)-2-propenoic acid …
Matched Iupac: … (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoic acid …
Matched Categories: … Indicators and Reagents …
Sodium oxybate (Xyrem) is a central nervous system (CNS) depressant used to treat cataplexy or excessive daytime sleepiness associated with narcolepsy. It is a sodium salt of gamma-Hydroxybutyric acid, an endogenous cerebral inhibitory neurotransmitter and a metabolite of the inhibitory neurotransmitter GABA. Due to its physiological effects, sodium oxybate is...
Approved
Matched Synonyms: … Oxybate sodium ... Sodium oxybate …
Matched Name: … Sodium oxybate …
Matched Iupac: … sodium 4-hydroxybutanoate …
Matched Description: … Sodium oxybate has been misused to stimulate body growth and to induce euphoria, disinhibition, and sexual ... [L46302] In some countries, sodium oxybate has been investigated and used in alcohol withdrawal syndrome ... and abuse. …
Matched Categories: … sodium oxybate ... sodium oxybate …
Matched Products: … Sodium Oxybate ... SODIO OXIBATO ACCORD ... SODIO OXIBATO ARISTO …
Investigational
Matched Synonyms: … (r)-1-(1-(4-acetoxy-3,3-dimethyl-2-oxo-butyl)-2-oxo-5-(pyridin-2-yl)-2,3-dihydro-1h-benzo(e)(1,4)diazepin ... -3-yl)-3-(3-methylamino-phenyl)-urea ... -3-yl)-n'-(3-(methylamino)phenyl)- …
Matched Iupac: … 2,2-dimethyl-4-[(3R)-3-({[3-(methylamino)phenyl]carbamoyl}amino)-2-oxo-5-(pyridin-2-yl)-2,3-dihydro-1H ... -1,4-benzodiazepin-1-yl]-3-oxobutyl acetate …
Approved
Matched Synonyms: … Sodium iodohippurate (123 I) ... sodium iodohippurate (123I) …
Matched Name: … Iodohippurate sodium I-123 …
Matched Iupac: … sodium 2-{[2-(¹²³I)iodophenyl]formamido}acetate …
Matched Categories: … sodium iodohippurate (123I) …
Approved
Experimental
Matched Synonyms: … Sodium vanadate ... Sodium vanadate(V) ... Sodium trioxovanadate …
Matched Name: … Sodium metavanadate …
Matched Iupac: … sodium vanadiumoylolate …
Matched Mixtures name: … Milltrium Senior Vitamin and Mineral Supplement ... Multivitamins and Minerals Tablets ... Spectrum Performa Multivitamins and Minerals Tablets …
Matched Salts name: … Sodium metavanadate tetrahydrate …
Matched Categories: … Ions
Human interferon beta (166 residues), glycosylated, MW=22.5kD. It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta gene has been introduced. The amino acid sequence is identical to that of natural human interferon beta.
Approved
Investigational
Matched Categories: … Cytochrome P-450 CYP1A2 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP1A2 Inhibitors (strength unknown) ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … REBIF 44 MCG (12MIU) KULLANIMA HAZIR SIRINGADA ENJEKSİYONLUK ÇÖZELTİ, 3 ADET ... AVONEX 30 MCG/0,5 ML KULLANIMA HAZIR DOLU ENJEKSIYON KALEMI ICINDE ENJEKSIYONLUK COZELTI, 4 ADET ... Avonex Pen
Acenocoumarol is a coumarin derivative used as an anticoagulant. Coumarin derivatives inhibit the reduction of vitamin K by vitamin K reductase. This prevents carboxylation of vitamin K-dependent clotting factors, II, VII, IX and X, and interferes with coagulation. Hematocrit, hemoglobin, international normalized ratio and liver panel should be monitored. Patients...
Approved
Investigational
Matched Synonyms: … 3-(alpha-Acetonyl-p-nitrobenzyl)-4-hydroxycoumarin ... 3-(alpha-(p-Nitrophenol)-beta-acetylethyl)-4-hydroxycoumarin ... 3-(alpha-p-Nitrophenyl-beta-acetylethyl)-4-hydroxycoumarin …
Matched Iupac: … 4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one …
Matched Description: … This prevents carboxylation of vitamin K-dependent clotting factors, II, VII, IX and X, and interferes ... [A188739] Hematocrit, hemoglobin, international normalized ratio and liver panel should be monitored. …
Matched Categories: … Blood and Blood Forming Organs ... Warfarin and isomers ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates ... Cytochrome P-450 CYP2C19 Substrates …
Matched Products: … Sintrom 4 mg Tabletten …
Sepantronium is a compound that suppresses survivin expression in a dose and time-dependent manner, and causes broad-range apoptosis.
Investigational
Matched Synonyms: … 1h-naphth(2,3-d)imidazolium, 4,9-dihydro-1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(2-pyrazinylmethyl)- ... Sepantronium ion
Matched Iupac: … 3-(2-methoxyethyl)-2-methyl-4,9-dioxo-1-[(pyrazin-2-yl)methyl]-1H,4H,9H-naphtho[2,3-d]imidazol-3-ium …
Matched Description: … Sepantronium is a compound that suppresses survivin expression in a dose and time-dependent manner, and
Matched Salts name: … Sepantronium bromide
Guanfacine, or BS 100-141,[A189838,A189841] is a selective alpha-A2 adrenergic receptor agonist initially indicated for the treatment of hypertension but is now indicated as an extended release tablet for the treatment of ADHD. Guanfacine was first described in the literature in 1974. Guanfacine was granted FDA approval on 27 October 1986.
Approved
Investigational
Matched Description: … alpha-A2 adrenergic receptor agonist initially indicated for the treatment of hypertension[L11274] but
Matched Salts cas: … 29110-48-3
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates ... Cytochrome P-450 CYP2C19 Substrates …
Matched Products: … Pro-guanfacine XR ... GUAGO 4 MG UZATILMIŞ SALIMLI TABLET, 28 ADET ... ARİSLOW ER 4 MG UZATILMIŞ SALIMLI TABLET, 28 TABLET …
Ligustrazine is under investigation in clinical trial NCT05942352 (Clinical Study of Ligustrazine in Treating Alcohol Addiction).
Investigational
Matched Synonyms: … 2,3,5,6-tetramethylpyrazine ... Pyrazine, 2,3,5,6-tetramethyl- …
A sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide.
Approved
Investigational
Matched Synonyms: … 4-(p-Tolylsulfonyl)-1,1-hexamethylenesemicarbazide ... 1-(Hexahydro-1-azepinyl)-3-p-tolylsulfonylurea ... 1-(Hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)urea …
Matched Iupac: … 1-(azepan-1-yl)-3-(4-methylbenzenesulfonyl)urea …
Matched Description: … A sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide. …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Substrates ... Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Methylprednisolone is a prednisolone derivative glucocorticoid with higher potency than prednisone. It was first described in the literature in the late 1950s.[A188811,A188814] Methylprednisolone was granted FDA approval on 24 October 1957. In the outbreak of COVID-19, low dose methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with...
Approved
Vet approved
Matched Iupac: … ,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one ... (1R,3aS,3bS,5S,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH
Matched Description: … methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with long-term
Matched Salts cas: … 53-36-1 …
Matched Mixtures name: … Dyural 40 Kit ... Dyural 40 Kit ... Methylprednisolone Sodium Succinate for Injection, USP …
Matched Categories: … Sex Hormones and Insulins ... methylprednisolone and antibiotics ... methylprednisolone and antiinfectives ... methylprednisolone and antiinfectives ... Ophthalmological and Otological Preparations …
Matched Products: … PREDNOL-L 40 MG LİYOFİLİZE ENJEKTABL AMPUL, 3 ADET ... METILPREDNISOLONA SODIO SUCCINATO. METIL PREDNISOLONA 500 MG. PARA RECONSTITUIR A 4 ML. ... Urbason solubile 32 mg Trockenampullen mit Lösungsmittel …
Cholesteryl chloride, also known as 3-chlorocholest-5-ene, is an organochloride derivative of cholesterol. It is presented as a liquid crystal that forms clockwise liquid crystals.
Experimental
Matched Synonyms: … Cholesterol chloride ... 3-Chlorocholestene ... 3-Chlorocholest-5-ene …
Matched Name: … Cholesteryl chloride
Matched Iupac: … (1R,3aS,3bS,7S,9aR,9bS,11aR)-7-chloro-9a,11a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-1H,2H,3H,3aH,3bH,4H
Matched Description: … Cholesteryl chloride, also known as 3-chlorocholest-5-ene, is an organochloride derivative of cholesterol …
Investigational
Matched Synonyms: … (5-amino-1-(4-fluoro-phenyl)-1h-pyrazol-4-yl)-(3-(2,3-dihydroxy-propoxy)-phenyl)-methanone ... [5-Amino-1-(4-fluoro-phenyl)-1H-pyrazol-4-yl]-[3-(2,3-dihydroxy-propoxy)-phenyl]-methanone ... Methanone, (5-amino-1-(4-fluorophenyl)-1h-pyrazol-4-yl)(3-(2,3-dihydroxypropoxy)phenyl)- …
Matched Iupac: … 3-{3-[5-amino-1-(4-fluorophenyl)-1H-pyrazole-4-carbonyl]phenoxy}propane-1,2-diol
Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972. Amoxicillin has similar activity to penicillin and ampicillin, but leads to higher serum concentrations than ampicillin. Amoxicillin was granted FDA approval on 18 January 1974.
Approved
Vet approved
Matched Synonyms: … (2S,5R,6R)-6-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0 ... p-Hydroxyampicillin ... α-amino-p-hydroxybenzylpenicillin …
Matched Iupac: … (2S,5R,6R)-6-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0 …
Matched Description: … [A190648] Amoxicillin has similar activity to [penicillin] and [ampicillin], but leads to higher serum …
Matched Mixtures name: … PMS-amclav-400 ... BROMIXEN ... BROMIXEN
Matched Salts name: … Amoxicillin sodium
Matched Categories: … Cytochrome P-450 CYP2C8 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP2C8 Inhibitors (weak) ... Alimentary Tract and Metabolism ... vonoprazan and amoxicillin …
Matched Products: … AMOXICILLIN SODIUM ... AMOKSILIN 250 MG KAPSÜL, 30 ADET ... MOXYLIN 3 G POLVO PARA SUSPENSION …
Experimental
Matched Synonyms: … EDTA sodium ... Edetate sodium ... Sodium edetate …
Matched Name: … Edetate sodium
Matched Categories: … sodium edetate …
N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine is a component of black rubber. It is also a dermatological sensitizer and allergen. Sensitivity to N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine may be identified with a clinical patch test.
Approved
Matched Synonyms: … N-Cyclohexyl-N'-phenyl-p-phenylendiamine ... N-cyclohexyl-N'-phenyl-p-phenylenediamine ... N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine …
Matched Name: … N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine …
Matched Description: … It is also a dermatological sensitizer and allergen. ... N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine is a component of black rubber. ... Sensitivity to N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine may be identified with a clinical patch test …
Imatinib is a small molecule kinase inhibitor that revolutionized the treatment of cancer, particularly chronic myeloid leukemia, in 2001. It was deemed a "miracle drug" due to its clinical success, as oncologist Dr. Brian noted that "complete hematologic responses were observed in 53 of 54 patients with CML treated with...
Approved
Matched Synonyms: … α-(4-methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-p-toluidide …
Matched Iupac: … N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)-4-[(4-methylpiperazin-1-yl)methyl]benzamide …
Matched Description: … mg or more and typically occurred in the first four weeks of therapy". ... [L42220] Imatinib was approved on February 1st ,2001 by the FDA and November 7th, 2001 by the EMA ... complete hematologic responses were observed in 53 of 54 patients with CML treated with a daily dosage of 300
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Benzamides and benzamide derivatives ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates ... Cytochrome P-450 CYP2C8 Substrates …
Matched Products: … PMS-imatinib ... IMANIVEC 100MG DISP TBL ... IMANIVEC 400MG DISP TBL …
Indigofera tinctoria leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Indigo Leaf ... Nila Leaf ... Nili Leaf
Matched Name: … Indigofera tinctoria leaf
Matched Description: … Indigofera tinctoria leaf is a plant/plant extract used in some OTC (over-the-counter) products. …
Displaying drugs 776 - 800 of 5758 in total