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Displaying drugs 776 - 800 of 4620 in total
norUrsodeoxycholic acid is under investigation in clinical trial NCT03872921 (Norursodeoxycholic Acid vs Placebo in PSC).
Investigational
Matched Synonyms: … Norucholic acid ... 24-norursodeoxycholic acid ... Nor-ursodeoxycholic acid
Matched Name: … norUrsodeoxycholic acid
Matched Iupac: … [a]phenanthren-1-yl]butanoic acid ... (3R)-3-[(1R,3aS,3bR,4S,5aS,7R,9aS,9bS,11aR)-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta …
Matched Description: … norUrsodeoxycholic acid is under investigation in clinical trial NCT03872921 (Norursodeoxycholic Acid
Matched Categories: … Bile Acids and Salts ... Cholic Acids
Porphobilinogen is a pyrrole involved in porphyrin metabolism. It is generated by the enzyme ALA dehydratase, and converted into hydroxymethyl bilane by the enzyme porphobilinogen deaminase.
Experimental
Matched Synonyms: … 5-(Aminomethyl)-4-(carboxymethyl)-1H-pyrrole-3-propionic acid
Matched Iupac: … 3-[5-(aminomethyl)-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid
Matched Description: … It is generated by the enzyme ALA dehydratase, and converted into hydroxymethyl bilane by the enzyme …
Ziltivekimab is under investigation in clinical trial NCT06200207 (A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation).
Investigational
Matched Synonyms: … Immunoglobulin g1 (255-tyrosine,257-threonine,259-glutamic acid), anti-(human interleukin 6) (human monoclonal …
Matched Description: … Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Balsalazide is an anti-inflammatory drug used in the treatment of Inflammatory Bowel Disease. It is sold under the name "Colazal" in the US and "Colazide" in the UK. The chemical name is (E)-5-[[-4-(2-carboxyethyl) aminocarbonyl] phenyl]azo] -2-hydroxybenzoic acid. It is usually administered as the disodium salt. Balsalazide works by deliverying mesalazine...
Approved
Investigational
Matched Synonyms: … (E)-5-({p-[(2-carboxyethyl)carbamoyl]phenyl}azo)-2-salicylic acid ... 5-[4-(2-carboxy-ethylcarbamoyl)-phenylazo]-2-hydroxy-benzoic acid ... (E)-5-((4-(((2-carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxybenzoic acid
Matched Iupac: … 5-[(1E)-2-{4-[(2-carboxyethyl)carbamoyl]phenyl}diazen-1-yl]-2-hydroxybenzoic acid
Matched Description: … Mesalazine is also known as 5-aminosalicylic acid, or 5-ASA. ... It is sold under the name "Colazal" in the US and "Colazide" in the UK. ... The chemical name is (E)-5-[[-4-(2-carboxyethyl) aminocarbonyl] phenyl]azo] -2-hydroxybenzoic acid. …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Carbocyclic ... Hydroxy Acids ... Aminosalicylic Acids ... Carboxylic Acids
Experimental
Matched Synonyms: … 3-Hydroxypropanoic acid ... 3-Hydroxypropionic acid ... β-hydroxypropionic acid
Matched Name: … Hydracrylic acid
Matched Iupac: … 3-hydroxypropanoic acid
Matched Categories: … Hydroxy Acids ... Carboxylic Acids
Experimental
Matched Synonyms: … Phosphomethylphosphonic acid adenosyl ester ... Adenosine 5'-(hydrogen (phosphonomethyl)phosphonate) ... Adenosine, 5'-(trihydrogen methylenebis(phosphonate)) …
Matched Name: … Adenosine 5'-methylenediphosphate …
Matched Iupac: … ]phosphonic acid ... [({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)methyl …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... 5'-Nucleotidase, antagonists & inhibitors …
Ropinirole, also known as ReQuip, is a non-ergoline dopamine agonist used in Parkinson's disease and restless legs syndrome [FDA label], . It is manufactured by GlaxoSmithKline Pharmaceuticals. Ropinirole was initially approved in 1997 by the FDA [FDA label] for the management of Parkinson's disease. In 2005, it was the first...
Approved
Investigational
Matched Description: … Ropinirole, also known as _ReQuip_, is a non-ergoline dopamine agonist used in Parkinson's disease and ... offering a similar side effect profile and efficacy to previous formulations of ropinirole [A35711]. ... capsules of ropinirole were approved, allowing for less frequent dosing, therefore increased compliance, and
Matched Salts name: … Ropinirole Hydrochloride
Matched Products: … ROPINIROL ACIS 2MG ... Ropinirole Hydrochloride ... ROPINIROL DURA 5MG
Experimental
Matched Synonyms: … 2-Ureidobutanedioic acid ... Ureidosuccinic acid ... L-N-Carbamoylaspartic acid
Matched Name: … N-Carbamoylaspartic acid
Matched Iupac: … (2S)-2-(carbamoylamino)butanedioic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Amino Acids, Dicarboxylic ... Excitatory Amino Acids
Commonly found in salts with sodium and calcium. Gluconic acid or gluconate is used to maintain the cation-anion balance on electrolyte solutions.
Approved
Investigational
Matched Synonyms: … D-Gluconic Acid ... Dextronic acid ... Maltonic acid
Matched Name: … Gluconic Acid
Matched Iupac: … (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoic acid
Matched Description: … Commonly found in salts with sodium and calcium. ... Gluconic acid or gluconate is used to maintain the cation-anion balance on electrolyte solutions. …
Matched Salts cas: … 527-07-1 …
Matched Mixtures name: … Plasma-Lyte 148 and dextrose ... Normosol-R and Dextrose ... Normosol-R and Dextrose …
Matched Categories: … Acids, Acyclic ... Sugar Acids ... Hydroxy Acids ... Carboxylic Acids
Investigational
Matched Synonyms: … Undecoic acid ... Hendecanoic acid ... Undecylic acid
Matched Name: … Undecanoic acid
Matched Iupac: … undecanoic acid
Investigational
Matched Synonyms: … HEME IRON
Matched Iupac: … lambda2-iron(2+) 4,20-bis(2-carboxyethyl)-10,15-diethenyl-5,9,14,19-tetramethyl-21,22,23,24-tetraazapentacyclo …
Experimental
Matched Synonyms: … Phloretic acid ... Phloretinic acid ... Dihydro-p-coumaric acid
Matched Name: … Phloretic acid
Matched Iupac: … 3-(4-hydroxyphenyl)propanoic acid
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Approved
Experimental
Matched Synonyms: … (+)-lactic acid ... (S)-(+)-lactic acid ... (S)-lactic acid
Matched Name: … L-Lactic acid
Matched Iupac: … (2S)-2-hydroxypropanoic acid
Matched Categories: … Hydroxy Acids ... Carboxylic Acids
An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia.
Approved
Matched Synonyms: … 5-Allyl-5-(3-hexyn-2-yl)-1-methylbarbituric acid ... (±)-5-allyl-1-methyl-5-(1-methyl-2-pentynyl)barbituric acid ... α-DL-1-methyl-5-allyl-5-(1'-methylpentyn-2-yl)barbituric acid
Matched Iupac: … 5-(hex-3-yn-2-yl)-1-methyl-5-(prop-2-en-1-yl)-1,3-diazinane-2,4,6-trione …
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … Brietal 500 mg - Trockenstechampulle …
Ataluren is a novel, orally administered drug that targets nonsense mutations. Ataluren is approved for use by the European Medicines Agency to treat Duchenne Muscular Dystrophy in patients aged 5 years and older who are able to walk. More specifically, ataluren is used in the small group of patients whose...
Approved
Investigational
Matched Synonyms: … 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid
Matched Iupac: … 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid
Matched Description: … years and older who are able to walk. ... This drug does not yet have approval by the US Food and Drug Administration or by Health Canada for any ... approved for use by the European Medicines Agency to treat Duchenne Muscular Dystrophy in patients aged 5
Experimental
Matched Synonyms: … Ketomalonic acid ... Oxomalonic acid ... alpha-Ketomalonic acid
Matched Name: … Mesoxalic acid
Matched Iupac: … 2-oxopropanedioic acid
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids
Experimental
Matched Synonyms: … (-)-Tartaric acid ... (−)-D-tartaric acid ... D-tartaric acid
Matched Name: … D-tartaric acid
Matched Iupac: … (2S,3S)-2,3-dihydroxybutanedioic acid
Experimental
Matched Synonyms: … (−)-3-hydroxymyristic acid ... (3R)-hydroxymyristic acid ... β-hydroxymyristic acid
Matched Name: … (R)-3-hydroxytetradecanoic acid
Matched Iupac: … (3R)-3-hydroxytetradecanoic acid
Originally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability and was soon repurposed. Hydralazine is a hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hypertension and only as adjunct therapy in the treatment of heart failure.[A186820,L8782,L8785] Hydralazine is no longer a...
Approved
Matched Description: … Originally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability and ... hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hypertension and ... [T691] Hydralazine hydrochloride was FDA approved on 15 January 1953.[L8779] …
Matched Mixtures name: … TRI NORMIN 50 ... Isosorbide dinitrate and hydralazine hydrochloride ... Isosorbide Dinitrate and Hydralazine Hydrochloride
Matched Salts name: … Hydralazine hydrochloride
Matched Categories: … hydralazine and diuretics ... Hydrazinophthalazine Derivatives and Diuretics ... Medications that reduce magnesium levels …
Matched Products: … ไดลาซิน 50 ... ไฮดรา 50 เอฟซี ... Hydralazine-50 Tab …
Experimental
Matched Synonyms: … 2-methyl-propionic acid ... iso-butyric acid ... 2-Methylpropanoic acid
Matched Name: … Isobutyric acid
Matched Iupac: … 2-methylpropanoic acid
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
Buspirone is a novel anxiolytic agent with a unique structure and a pharmacological profile. Belonging to the azaspirodecanedione drug class, buspirone is a serotonin 5-HT1A receptor agonist that is not chemically or pharmacologically related to benzodiazepines, barbiturates, and other sedative/anxiolytic drugs. Unlike many drugs used to treat anxiety, buspirone does...
Approved
Investigational
Matched Description: … Buspirone is a novel anxiolytic agent with a unique structure and a pharmacological profile. ... , such as generalized anxiety disorder (GAD), and relieve symptoms of anxiety. ... receptor agonist that is not chemically or pharmacologically related to benzodiazepines, barbiturates, and
Matched Salts name: … Buspirone hydrochloride
Matched Categories: … Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … Buspirone Hydrochloride ... BusPIRone Hydrochloride ... Buspirone hydrochloride
Experimental
Matched Synonyms: … Ethylenesulfonic acid ... Vinylsulphonic acid
Matched Name: … Vinylsulfonic acid
Matched Iupac: … ethenesulfonic acid
Matched Categories: … Acids ... Sulfur Acids ... Acids, Noncarboxylic …
An antitubercular agent often administered in association with isoniazid. The sodium salt of the drug is better tolerated than the free acid.
Approved
Matched Synonyms: … Aminosalicylic acid ... 4-aminosalicylic acid ... p-aminosalicylic acid
Matched Name: … Aminosalicylic acid
Matched Iupac: … 4-amino-2-hydroxybenzoic acid
Matched Description: … The sodium salt of the drug is better tolerated than the free acid. …
Matched Salts cas: … 133-09-5 ... 6018-19-5
Matched Salts name: … Aminosalicylate calcium ... Calcium aminosalicylate trihydrate …
Matched Categories: … Aminosalicylic Acid and Derivatives ... calcium aminosalicylate ... Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids
Experimental
Matched Name: … 3-(Phosphonomethyl)Pyridine-2-Carboxylic Acid
Matched Iupac: … 3-(phosphonomethyl)pyridine-2-carboxylic acid
In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614]. The result of doing so allows cGMP present in both the penis and pulmonary vasculature to...
Approved
Investigational
Matched Synonyms: … 1-((3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl) …
Matched Iupac: … 5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1H,4H,7H-pyrazolo[4,3-d]pyrimidin …
Matched Description: … breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 ... it to grow in size and become erect and rigid [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614 ... The result of doing so allows cGMP present in both the penis and pulmonary vasculature to elicit smooth …
Matched Mixtures name: … DAPOKSEL 30 MG/50 MG FILM TABLET ,3 FILM TABLET ... DAPOKSEL 30 MG/50 MG FILM TABLET ,6 FILM TABLET ... DAPOXIL 30/50 MG FILM KAPLI TABLET,18 FILM KAPLI TABLET …
Matched Salts name: … Sildenafil citrate
Matched Categories: … Phosphodiesterase 5 Inhibitors …
Matched Products: … SIFE 50 SILDENAFIL CITRATE FILM COATED TABLETS 50 MG ... GIAGRA 50 (SILDENAFIL CITRATE TABLETS 50MG) ... Sildenafil Citrate
Displaying drugs 776 - 800 of 4620 in total