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Displaying drugs 776 - 800 of 3383 in total

Methotrexate

Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. This inhibition leads to suppression of inflammation as well as prevention of cell division. Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases such...
Approved
Matched Synonyms: … N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid ... 4-amino-10-methylfolic acid ... 4-amino-N(10)-methylpteroylglutamic acid …
Matched Iupac: … -[(4-{[(4-amino-2-imino-2,3-dihydropteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic acid …
Matched Description: … of some forms of arthritis and severe psoriasis only if first line treatment has failed or patients ... inflammation caused by arthritis or to control cell division in neoplastic diseases such as breast cancer and ... Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Folic Acid Analogues ... Folic Acid Antagonists ... Nucleic Acid Synthesis Inhibitors …
Matched Products: … Zexate® Solution for Injection or Infusion 25 mg/ml ... TREXOL - Methotrexate Solution for Injection 25 mg/ml ... TREXOL - Methotrexate Solution for Injection 100 mg/ml …

2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid

Experimental
Matched Name: … 2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid …
Matched Iupac: … (2R)-2-[(N-hydroxyformamido)methyl]-4-methylpentanoic acid …

Vildagliptin

Vildagliptin (LAF237) is an orally active antihyperglycemic agent that selectively inhibits the dipeptidyl peptidase-4 (DPP-4) enzyme. It is used to manage type II diabetes mellitus, where GLP-1 secretion and insulinotropic effects are impaired. By inhibiting DPP-4, vildagliptin prevents the degradation of glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP),...
Approved
Investigational
Matched Description: … It is marketed as Galvus. ... It is used to manage type II diabetes mellitus, where GLP-1 secretion and insulinotropic effects are ... Elevated levels of GLP-1 and GIP consequently results in improved glycemic control. …
Matched Mixtures name: … GALVUS MET ... GALVUS MET (50MG/500 MG) ... GALVUS MET (50 MG/850 MG) …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and vildagliptin …
Matched Products: … GALVUS ... Galvus ... GALVUS 50 MG …

Metronidazole benzoate

Experimental
Matched Synonyms: … Benzoyl metronidazole ... Metronidazol benzoilo …
Matched Mixtures name: … METRO FORT ... METRONIDAZOL BENZOILO/ NIFUROXAZIDA 250MG + 200MG/5 ML SUSPENSION …
Matched Products: … METRONIDAZOLE BENZOAT …

RU85053

Experimental
Matched Synonyms: … acid ... Acetamido-3-oxo-3-[[(3S)-2-oxo-1-[(4-phenylphenyl)methyl]azepan-3-yl]amino]propyl]-2-(carboxymethyl)benzoic …
Matched Iupac: … acid ... 3S)-1-({[1,1'-biphenyl]-4-yl}methyl)-2-oxoazepan-3-yl]carbamoyl}-2-acetamidoethyl]-2-(carboxymethyl)benzoic …

Sennosides

Sennosides (also known as senna glycoside or senna) is a medication used to treat constipation[FDA Label] and empty the large intestine before surgery. The medication is taken by mouth or via the rectum[FDA Label]. It typically begins working in minutes when given by rectum and within twelve hours when given...
Experimental
Matched Iupac: … 3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy})-9H,9'H,10H,10'H-[9,9'-bianthracene]-2,2'-dicarboxylic acid …
Matched Description: … also known as senna glycoside or senna) is a medication used to treat constipation[FDA Label][L771] and ... It typically begins working in minutes when given by rectum and within twelve hours when given by mouth …
Matched Mixtures name: … Sennosides and Docusate Sodium ... Senna and Docusate Sodium ... Senna and Docusate Sodium …
Matched Salts name: … Sennosides A and B …
Matched Categories: … Alimentary Tract and Metabolism ... Herbs and Natural Products ... Drugs for Constipation …
Matched Products: … Calcium Sennosides 20% ... Calcium Sennosides 60% ... Lax-Aid for Children …

Balsalazide

Balsalazide is an anti-inflammatory drug used in the treatment of Inflammatory Bowel Disease. It is sold under the name "Colazal" in the US and "Colazide" in the UK. The chemical name is (E)-5-[[-4-(2-carboxyethyl) aminocarbonyl] phenyl]azo] -2-hydroxybenzoic acid. It is usually administered as the disodium salt. Balsalazide works by deliverying mesalazine...
Approved
Investigational
Matched Synonyms: … 5-[4-(2-carboxy-ethylcarbamoyl)-phenylazo]-2-hydroxy-benzoic acid ... (E)-5-({p-[(2-carboxyethyl)carbamoyl]phenyl}azo)-2-salicylic acid ... (E)-5-((4-(((2-carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxybenzoic acid …
Matched Iupac: … 5-[(1E)-2-{4-[(2-carboxyethyl)carbamoyl]phenyl}diazen-1-yl]-2-hydroxybenzoic acid …
Matched Description: … It is sold under the name "Colazal" in the US and "Colazide" in the UK. ... Mesalazine is also known as 5-aminosalicylic acid, or 5-ASA. ... The chemical name is (E)-5-[[-4-(2-carboxyethyl) aminocarbonyl] phenyl]azo] -2-hydroxybenzoic acid. …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Carbocyclic ... Hydroxy Acids ... Aminosalicylic Acids ... Carboxylic Acids …

Calcium citrate

Calcium citrate is a salt typically used as a source of calcium in a variety of over the counter supplements.
Approved
Investigational
Matched Name: … Calcium citrate …
Matched Description: … Calcium citrate is a salt typically used as a source of calcium in a variety of over the counter supplements …
Matched Mixtures name: … Derma-force ... Calcium and Mag-potass and Zinc Cap ... Calcium, Magnesium, Zinc and D …
Matched Salts name: … Calcium citrate malate ... Calcium citrate tetrahydrate …
Matched Categories: … ascorbic acid (vit C) and calcium ... Calcium-Regulating Hormones and Agents ... Alimentary Tract and Metabolism ... Diet, Food, and Nutrition ... Acids, Acyclic …
Matched Products: … Calcium 350 Mg (calcium Citrate) - Caplet ... Calcium 350 Mg (calcium Citrate) Caplet ... Calcium Citrate …

7-methyl-5'-guanylic acid

Experimental
Matched Synonyms: … 7-methylguanosine 5'-phosphate ... 7-methylguanosine 5'-(dihydrogen phosphate) …
Matched Name: … 7-methyl-5'-guanylic acid …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Nucleic Acids …

1,6-Fructose Diphosphate (Linear Form)

Experimental
Matched Name: … 1,6-Fructose Diphosphate (Linear Form) …
Matched Iupac: … {[(3S,4S,5R)-3,4,5-trihydroxy-2-oxo-6-(phosphonooxy)hexyl]oxy}phosphonic acid …

Pralatrexate

Pralatrexate is an antifolate for the treatment of relapsed or refractory peripheral T-cell lymphoma . Pralatrexate was developed in response due to the inferior responses of patients using the standard therapy for their B-cells counterparts. Compared to methotrexate, pralatrexate has better accumulation in cancer cells. Pralatrexate is designed to have...
Approved
Investigational
Matched Synonyms: … N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acid ... (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}amino)pentanedioic acid ... (2S)-2-((4-((1RS)-1-((2,4-Diaminopteridin-6-yl)methyl)but-3-ynyl)benzoyl)amino)pentanedioic acid …
Matched Iupac: … (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]phenyl}formamido)pentanedioic acid …
Matched Description: … [L37674] It is also being studied for other types of lymphoma and solid malignancy such as non-small-cell ... lung cancer, breast cancer, and bladder cancer. ... that is overexpressed in malignant cells and is upregulated by oncogenes. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Folic Acid Analogues ... Folic Acid Antagonists …
Matched Products: … SOLUTION FOR INFUSION 20MG/ML ... Folotyn 20mg/ml Solution for Infusion …

Sodium cellulose phosphate

Sodium cellulose phosphate is used to treat hypercalcemia and hypercalciuria. It has been used to prevent kidney stones. This compound is an ion-exchange resin that can not be absorbed by the body. However, it can be used to restore normal intestinal calcium absorption.
Approved
Matched Synonyms: … Cellulose sodium phosphate ... Cellulose disodium phosphate ... Cellulose dihydrogen phosphate, disodium salt …
Matched Name: … Sodium cellulose phosphate …
Matched Description: … Sodium cellulose phosphate is used to treat hypercalcemia and hypercalciuria. ... However, it can be used to restore normal intestinal calcium absorption. ... [A31694] This compound is an ion-exchange resin that can not be absorbed by the body. …
Matched Categories: … Cation Exchange Resins ... sodium cellulose phosphate ... Drugs for Treatment of Hypercalcemia ... Calcium Binder ... Calcium Chelating Activity …

Mebendazole

A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. [PubChem]
Approved
Vet approved
Matched Synonyms: … (5-benzoyl-1H-benzimidazol-2-yl)-carbamic acid methyl ester …
Matched Iupac: … methyl N-(6-benzoyl-1H-1,3-benzodiazol-2-yl)carbamate …
Matched Description: … A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Acids, Acyclic ... Carboxylic Acids …

Alpha-D-mannose 1-phosphate

Investigational
Matched Synonyms: … -d-mannose 1-phosphate ... Mannose 1-phosphate, .alpha.-d- ... -d-mannopyranose, 1-(dihydrogen phosphate) …
Matched Name: … Alpha-D-mannose 1-phosphate …
Matched Iupac: … {[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phosphonic acid …

Fenoprofen

An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.
Approved
Matched Synonyms: … (+/-)-m-phenoxyhydratropic acid ... 3-phenoxyhydratropic acid ... 2-(3-phenoxyphenyl)propionic acid …
Matched Iupac: … 2-(3-phenoxyphenyl)propanoic acid …
Matched Description: … An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. …
Matched Salts name: … Fenoprofen calcium …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Carbocyclic ... Carboxylic Acids ... Arylpropionic acid NSAIDS …
Matched Products: … Fenoprofen Calcium …

PLX51107

PLX51107 is a potent and selective inhibitor of the bromodomain and extraterminal (BET) protein family.[A257246,A257251] PLX51107 is under investigation in clinical trial NCT04022785 (PLX51107 and Azacitidine in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome).
Investigational
Matched Synonyms: … Benzoic acid, 4-(6-(3,5-dimethyl-4-isoxazolyl)-1-((1s)-1-(2-pyridinyl)ethyl)-1h-pyrrolo(3,2-b)pyridin …
Matched Iupac: … 4-[6-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[1-(pyridin-2-yl)ethyl]-1H-pyrrolo[3,2-b]pyridin-3-yl]benzoic acid …
Matched Description: … PLX51107 is a potent and selective inhibitor of the bromodomain and extraterminal (BET) protein family ... [A257246,A257251] PLX51107 is under investigation in clinical trial NCT04022785 (PLX51107 and Azacitidine …

Vasopressin

Vasopressin (arginine-vasopressin or antidiuretic hormone) is a nonapeptide primarily produced in the hypothalamus that exhibits diverse physiological functions related to diuresis, hemodynamic modulation, and behaviour.[A110, A111, A112, A113, A228008] Vasopressin is very similar to oxytocin, differing in the third and eighth amino acids. Despite a wide variety of functions, exogenous...
Approved
Matched Synonyms: … Vasopressin, unspecified …
Matched Description: … eighth amino acids. ... insipidus, and, more recently, vasodilatory shock. ... hypothalamus that exhibits diverse physiological functions related to diuresis, hemodynamic modulation, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Vasopressin and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Pyridoxamine-5'-Phosphate

Experimental
Matched Synonyms: … Pyridoxamine phosphate …
Matched Name: … Pyridoxamine-5'-Phosphate …
Matched Iupac: … {[4-(aminomethyl)-5-hydroxy-6-methylpyridin-3-yl]methoxy}phosphonic acid …

Hydrocortisone phosphate

Approved
Vet approved
Matched Synonyms: … Cortisol 21-phosphate ... Hydrocortisone 21-phosphate …
Matched Name: … Hydrocortisone phosphate …
Matched Iupac: … 3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethoxy}phosphonic acid …
Matched Salts name: … Hydrocortisone sodium phosphate …
Matched Categories: … Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Clobetasol propionate

Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors. It has demonstrated superior activity compared to fluocinonide and was first described in the literature in 1974. Clobetasol Propionate was granted FDA approval on 27 December 1985.
Approved
Matched Description: … [L11815] It has demonstrated superior activity compared to [fluocinonide][A190963] and was first described ... Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors …
Matched Mixtures name: … Clobetasol Propionate 0.05% / Coal Tar 8% / Salicylic Acid 6% ... Ciclopirox Olamine 0.77% / Clobetasol Propionate 0.05% / Salicylic Acid 3%. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Clobetasol Propionate ANDA ... CLOBETASOL ACIS CREME ... CLOBETASOL ACIS SALBE …

RU84687

RU84687 is a subnanomolar and Src SH2 selective binder.
Experimental
Matched Synonyms: … N-acetyl-N-[1-(1,1'-biphenyl-4-ylmethyl)-2-oxoazepan-3-yl]-3-formyl-O-phosphonotyrosinamide …
Matched Iupac: … 1,1'-biphenyl]-4-yl}methyl)-2-oxoazepan-3-yl]carbamoyl}-2-acetamidoethyl]-2-formylphenoxy}phosphonic acid …
Matched Description: … RU84687 is a subnanomolar and Src SH2 selective binder. …

Fluconazole

Fluconazole, commonly known as Diflucan, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues. It was initially approved by the FDA in 1990. This drug is an azole antifungal, in the same drug family as ketoconazole and itraconazole. Fluconazole...
Approved
Investigational
Matched Description: … and superficial fungal infections in a variety of tissues. ... This drug is an _azole_ antifungal, in the same drug family as [ketoconazole] and [itraconazole]. ... Fluconazole, commonly known as _Diflucan_, is an antifungal drug used for the treatment of both systemic …
Matched Mixtures name: … Extra Strength Clotrimazole Extra Fort -fluconazole Combi …
Matched Categories: … Imidazole and Triazole Derivatives ... Triazole and tetrazole derivatives ... azithromycin, fluconazole and secnidazole ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Antifungals for Topical Use …
Matched Products: … FLUCONAZOL ACIS 50MG ... FLUCONAZOL ACIS 150MG ... FUZOLPAULY 200 MG CAPSULA …

(2r)-2-{[Formyl(Hydroxy)Amino]Methyl}Hexanoic Acid

Experimental
Matched Name: … (2r)-2-{[Formyl(Hydroxy)Amino]Methyl}Hexanoic Acid …
Matched Iupac: … (2R)-2-[(N-hydroxyformamido)methyl]hexanoic acid …

Liquidambar styraciflua resin

Experimental
Matched Synonyms: … Liquidambar macrophylla resin ... Liquidambar styraciflua resin …
Matched Name: … Liquidambar styraciflua resin …
Matched Mixtures name: … Benzoin ... Compound Benzoin Tincture ... Friar's Balsam Benzoin Tincture …

Karaya gum

Karaya gum allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Karaya resin ... Sterculia resin ... Sterculia urens resin …
Matched Categories: … Alimentary Tract and Metabolism ... Equipment and Supplies ... Bulk-Forming Laxatives ... Drugs for Constipation …
Displaying drugs 776 - 800 of 3383 in total