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Displaying drugs 776 - 800 of 5394 in total
Alosetron is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable bowel syndrome (IBS) in women. Alosetron has an antagonist action on the 5-HT3 receptors and thus may modulate serotonin-sensitive gastrointestinal (GI) processes. Alosetron was voluntarily withdrawn from the US market in November 2000 by the manufacturer...
Approved
Withdrawn
Matched Synonyms: … 2,3,4,5-Tetrahydro-5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-1H-pyrido(4,3-b)indol-1-one …
Matched Iupac: … 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-1H,2H,3H,4H,5H-pyrido[4,3-b]indol-1-one …
Matched Description: … Alosetron has an antagonist action on the 5-HT3 receptors and thus may modulate serotonin-sensitive gastrointestinal ... reports of severe adverse effects including ischemic colitis, severely obstructed or ruptured bowel, and ... Alosetron is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable …
Matched Salts name: … Alosetron hydrochloride
Matched Categories: … Alimentary Tract and Metabolism ... Serotonin 5-HT3 Receptor Antagonists ... Antiemetic Serotonin 5-HT3 Receptor Antagonists …
Matched Products: … Alosetron Hydrochloride
Methylphenidate is a central nervous system stimulant used most commonly in the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) and for narcolepsy. Also known as the marketed products Ritalin, Concerta, or Biphentin, methylphenidate is used with other treatment modalities (psychological, educational, cognitive behaviour therapy, etc) to improve the following group of developmentally...
Approved
Investigational
Matched Synonyms: … α-phenyl-2-piperidineacetic acid methyl ester …
Matched Description: … Methylphenidate's beneficial effects in sustaining attention have also been shown to be mediated by alpha ... products and amphetamines, have a high potential for abuse and dependence. ... the most effective and widely used treatment for ADHD, and are considered first-line options for children …
Matched Salts name: … Methylphenidate hydrochloride
Matched Categories: … Methylphenidate and isomer ... Respiratory and CNS Stimulants ... Psychostimulants, Agents Used for ADHD and Nootropics ... Acids, Carbocyclic ... Carboxylic Acids
Matched Products: … Methylphenidate Hydrochloride ... Methylphenidate hydrochloride ... Methylphenidate Hydrochloride (CD) …
An acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
Approved
Investigational
Matched Description: … An acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. …
Matched Salts name: … Ganciclovir sodium
Matched Categories: … Ganciclovir and prodrug ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors ... Nucleic Acid Synthesis Inhibitors ... Drugs that are Mainly Renally Excreted …
Matched Products: … Ganciclovir Sodium ... GANCICLOVIR SODIUM FOR INJECTION ... Cytovene, 500 mg …
Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors. Propranolol is used to treat a number of conditions but most commonly is used for hypertension.[L6901,L6904,L6907] Propranolol was granted FDA approval on 13 November 1967.
Approved
Investigational
Matched Description: … Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times ... [L6904] Propranolol is used to treat a number of conditions but most commonly is used for hypertension …
Matched Mixtures name: … Propranolol Hydrochloride and Hydrochlorothiazide ... Propranolol Hydrochloride and Hydrochlorothiazide ... Propranolol Hydrochloride and Hydrochlorothiazide …
Matched Salts name: … Propranolol hydrochloride
Matched Categories: … Beta Blocking Agents and Thiazides ... propranolol and thiazides ... propranolol and other combinations ... Beta Blocking Agents, Non-Selective, and Thiazides ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Products: … Propranolol Hydrochloride ... Propranolol Hydrochloride ER ... Propranolol hydrochloride
Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. Their well-characterized anti-inflammatory activity, analgesic property, and established safety record have also made NSAIDs an important tool for optimizing surgical outcomes. Non-ophthalmic formulations of bromfenac were...
Approved
Withdrawn
Matched Synonyms: … 2-amino-3-(4-bromobenzoyl)benzeneacetic acid ... [2-Amino-3-(4-bromo-benzoyl)-phenyl]-acetic acid
Matched Iupac: … 2-[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid
Matched Description: … Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. ... Their well-characterized anti-inflammatory activity, analgesic property, and established safety record ... Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. …
Matched Salts cas: … 120638-55-3 …
Matched Salts name: … Bromfenac sodium
Matched Products: … Bromfenac Sodium ... Apo-bromfenac …
Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972. Amoxicillin has similar activity to penicillin and ampicillin, but leads to higher serum concentrations than ampicillin. Amoxicillin was granted FDA approval on 18 January 1974.
Approved
Vet approved
Matched International brands: … Apo-Amoxi …
Matched Synonyms: … AX ... ]heptane-2-carboxylic acid ... (2S,5R,6R)-6-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0 …
Matched Iupac: … ]heptane-2-carboxylic acid ... (2S,5R,6R)-6-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0 …
Matched Description: … [A190648] Amoxicillin has similar activity to [penicillin] and [ampicillin], but leads to higher serum ... Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972. …
Matched Mixtures name: … Amoxicillin Sodium and Potassium Clavulanate for Injection ... Amoxicillin Sodium and Potassium Clavulanate for Injection ... Amoxicillin Sodium and Potassium Clavulanate for Injection …
Matched Salts name: … Amoxicillin sodium
Matched Categories: … Drugs for Acid Related Disorders ... Alimentary Tract and Metabolism ... vonoprazan and amoxicillin ... omeprazole, amoxicillin and rifabutin ... vonoprazan, amoxicillin and clarithromycin …
Matched Products: … AMOXICILLIN SODIUM ... AMOXICILLINA SODICA K24 PHARMACEUTICALS ... AMOXICILLINA E ACIDO CLAVULANICO PFIZER …
Experimental
Matched Synonyms: … 3'-Fluoro-3'-deoxythymidine 5'-phosphate ... 5'-Thymidylic acid, 3'-deoxy-3'-fluoro- ... 3'-Fluoro-3'-deoxythymidine 5'-monophosphate …
Matched Name: … 3'-Fluoro-3'-deoxythymidine 5'-monophosphate …
Matched Iupac: … acid ... {[(2R,3S,5R)-3-fluoro-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}phosphonic …
Tomivosertib is under investigation in clinical trial NCT03318562 (A PD Study of Oral eFT508 in Subjects With Advanced TNBC and HCC).
Investigational
Matched Synonyms: … 6'-((6-Amino-4-pyrimidinyl)amino)-8'-methyl-2'H-spiro(cyclohexane-1,3'-imidazo(1,5-a)pyridine)-1',5'- …
Matched Iupac: … 6'-[(6-aminopyrimidin-4-yl)amino]-8'-methyl-2',5'-dihydro-1'H-spiro[cyclohexane-1,3'-imidazo[1,5-a]pyridine ... ]-1',5'-dione …
Matched Description: … With Advanced TNBC and HCC). ... Tomivosertib is under investigation in clinical trial NCT03318562 (A PD Study of Oral eFT508 in Subjects …
Matched Salts name: … Tomivosertib hydrochloride
Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores of lead from the body. It is on the World Health Organization Model List of Essential Medicines. Edetate calcium disodium was granted FDA approval on 16 July 1953.
Approved
Matched Synonyms: … Edetic acid calcium disodium salt …
Matched Description: … Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores …
Matched Categories: … Diet, Food, and Nutrition ... Acids, Acyclic ... Carboxylic Acids ... Compounds used in a research, industrial, or household setting …
Matched Products: … Calcium Edetate de Sodium
Experimental
Matched Synonyms: … 5,6-dihydro-6-oxouridine 5'-phosphate ... 5,6-dihydro-6-oxouridine 5'-monophosphate …
Matched Name: … 6-oxouridine 5'-phosphate
Matched Iupac: … {[(2R,3S,4R,5R)-3,4-dihydroxy-5-(2,4,6-trioxo-1,3-diazinan-1-yl)oxolan-2-yl]methoxy}phosphonic acid
Remlarsen is under investigation in clinical trial NCT03601052 (Efficacy, Safety, and Tolerability of Remlarsen (MRG-201) Following Intradermal Injection in Subjects With a History of Keloids).
Investigational
Matched Synonyms: … -cholest-5-en-3-yloxy)hexyl)oxy)-2-hydroxypropyl hydrogen phosphate), complex with rna ((2'-deoxy-2'- ... Rna, (am-am-cm-a-cm-um-g-um-um-um-a-cm-a-a-a-um-g-g-um-cm-cm-um-a), 3'-(3-((6-((3.beta.) ... fluoro)u-a-g-(2'-deoxy-2'-fluoro)c-a-(2'-deoxy-2'-fluoro)c-(2'-de …
Matched Description: … Remlarsen is under investigation in clinical trial NCT03601052 (Efficacy, Safety, and Tolerability of ... Remlarsen (MRG-201) Following Intradermal Injection in Subjects With a History of Keloids). …
Drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and penicillin-resistant Streptococcus penumoniae, represent a massive public health threat.[A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the previously approved linezolid and is generally effective against multidrug-resistant Gram-positive bacteria. Tedizolid is indicated for the...
Approved
Matched Synonyms: … [(5R)-3-{3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin-5-yl]methyl ... Tedizolid phosphate ... Torezolid phosphate
Matched Name: … Tedizolid phosphate
Matched Iupac: … 5-yl]methoxy}phosphonic acid ... {[(5R)-3-{3-fluoro-4-[6-(2-methyl-2H-1,2,3,4-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin- …
Matched Description: … ) and is generally more effective and more tolerable than [linezolid]. ... This product is currently available as both an oral tablet and as a powder for intravenous injection. ... tedizolid phosphate (SIVEXTRO®). …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Ephedrine was first described in western literature in 1888, as a naturally occurring component of the ephedra plant, along with pseudoephedrine. Ephedrine acts as both a direct and indirect sympathomimetic. It is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of norepinephrine from sympathetic neurons,...
Approved
Matched Description: … It is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of ... [A193698] Ephedrine acts as both a direct and indirect sympathomimetic. ... [L12972] Ephedrine and [phenylephrine] are still used to treat hypotension, but their use in other indications …
Matched Salts cas: … 50-98-6 ... 134-72-5
Matched Mixtures name: … BROKSIN 6.66 MG/5 ML+100 MG/5 ML SURUP, 150 ML ... ColdaeWon Cold A ... ColdaeWon Cough A
Matched Salts name: … Ephedrine hydrochloride
Matched Categories: … Alpha-and Beta-adrenergic Agonists ... Adrenergic and Dopaminergic Agents ... Epinephrine and similars ... Alimentary Tract and Metabolism ... Herbs and Natural Products …
Matched Products: … EPHEDRINE HYDROCHLORIDE ... Ephedrine Hydrochloride ... Ephedrine Hydrochloride Tablets 25mg …
Protriptyline hydrochloride is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, protriptyline does not affect mood or arousal, but may cause sedation. In depressed individuals, protriptyline exerts a positive...
Approved
Matched Synonyms: … 3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-1-amine ... 5-(3-methylaminopropyl)-5H-dibenzo[a,d]cycloheptene ... N-methyl-5H-dibenzo[a,d]cycloheptene-5-propanamine …
Matched Description: … TCAs also block histamine H1 receptors, alpha1-adrenergic receptors and muscarinic ... Protriptyline hydrochloride is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA). ... TCAs are potent inhibitors of serotonin and norepinephrine reuptake. …
Matched Salts cas: … 1225-55-4 …
Matched Salts name: … Protriptyline hydrochloride
Matched Products: … Protriptyline Hydrochloride ... Protriptyline hydrochloride
Investigational
Matched Synonyms: … Thiasine
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Compounds used in a research, industrial, or household setting …
Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings. Most known for its approved indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and inpatient setting for atrial fibrillation. Because of its ability to cause serious toxicity and possibly death, amiodarone...
Approved
Investigational
Matched Synonyms: … 2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran …
Matched Description: … indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and ... Because of its ability to cause serious toxicity and possibly death, amiodarone use should be reserved ... Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings. …
Matched Salts name: … Amiodarone hydrochloride
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... Sodium Channel Blockers ... alpha-Galactosidase, antagonists & inhibitors ... BSEP/ABCB11 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index …
Matched Products: … Ava-amiodarone ... AMIODARON AL 200 ... Amiodarone Hydrochloride
Tizanidine is a fast-acting drug used for the management of muscle spasm, which may result from the effects of multiple sclerosis, stroke, an acquired brain injury, or a spinal cord injury . It may also be caused by musculoskeletal injury . Regardless of the cause, muscle spasticity can be an...
Approved
Investigational
Matched Synonyms: … 5-Chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazole …
Matched Iupac: … 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine …
Matched Description: … Regardless of the cause, muscle spasticity can be an extremely painful and debilitating condition. ... Initially approved by the FDA in 1996, tizanidine is an Alpha-2 adrenergic receptor agonist reducing ... of multiple sclerosis, stroke, an acquired brain injury, or a spinal cord injury [T574]. …
Matched Mixtures name: … ALERTADINA® A TABLETAS RECUBIERTAS …
Matched Salts name: … Tizanidine hydrochloride
Matched Categories: … Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Adrenergic alpha-Agonists ... Adrenergic alpha-2 Receptor Agonists ... Central alpha-2 Adrenergic Agonist …
Matched Products: … Apo-tizanidine ... Tizanidine Hydrochloride ... Tizanidine hydrochloride
Experimental
Matched Synonyms: … alpha-Toluenesulfonic acid ... Toluene-alpha-sulphonic acid ... Benzylsulfinic acid
Matched Name: … Benzylsulfonic acid
Matched Iupac: … phenylmethanesulfonic acid
Matched Categories: … Sulfur Acids ... Sulfonic Acids ... Alkanesulfonic Acids
Phentermine is a sympathomimetic amine anorectic agent and it was introduced in 1959 as part of an anti-obesity combination drug.[A174361, A174364] It is chemically related to amphetamine and it is commonly referred to as an atypical amphetamine. Phentermine has not been reported an addictive potential which allows this agent to...
Approved
Illicit
Matched Synonyms: … alpha,alpha-Dimethylphenethylamine …
Matched Description: … Phentermine is a sympathomimetic amine anorectic agent and it was introduced in 1959 as part of an anti-obesity ... [A174361, A174364] It is chemically related to amphetamine and it is commonly referred to as an atypical ... [A174376, T403] Later on, phentermine was approved alone and in combination with topiramate in 2012 as
Matched Salts name: … Phentermine hydrochloride
Matched Categories: … Alimentary Tract and Metabolism ... phentermine and topiramate ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Products: … ACXION AP. ... Phentermine Hydrochloride ... Phentermine hydrochloride
Cardioactive derivative of lanatoside A or of digitoxin used for fast digitalization in congestive heart failure.
Approved
Matched Synonyms: … Desglucolanatoside A ... Acetyl-digitoxin-alpha ... alpha-Acetyldigitoxin …
Matched Iupac: … 11a-dimethyl-1-(5-oxo-2,5-dihydrofuran-3-yl)-hexadecahydro-1H-cyclopenta[a]phenanthren-7-yl]oxy}-4-hydroxy ... (2R,3R,4S,6S)-6-{[(2R,3S,4S,6S)-6-{[(2R,3S,4S,6R)-6-{[(1R,3aS,3bR,5aR,7S,9aS,9bS,11aR)-3a-hydroxy-9a, …
Matched Description: … Cardioactive derivative of lanatoside A or of digitoxin used for fast digitalization in congestive heart …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Experimental
Matched Synonyms: … (5-oxo-5,6-dihydro-indolo[1,2-a]quinazolin-7-yl)-acetic acid
Matched Name: … (5-hydroxyindolo[1,2-a]quinazolin-7-yl)acetic acid
Matched Iupac: … 2-{5-oxo-5H,6H-indolo[1,2-a]quinazolin-7-yl}acetic acid
Vasopressin (arginine-vasopressin or antidiuretic hormone) is a nonapeptide primarily produced in the hypothalamus that exhibits diverse physiological functions related to diuresis, hemodynamic modulation, and behaviour.[A110, A111, A112, A113, A228008] Vasopressin is very similar to oxytocin, differing in the third and eighth amino acids. Despite a wide variety of functions, exogenous...
Approved
Matched Iupac: … -dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl]pyrrolidin-2-yl}formamido)-N-(carbamoylmethyl)-5- …
Matched Description: … V1 and V2 cellular receptors. ... eighth amino acids. ... hypothalamus that exhibits diverse physiological functions related to diuresis, hemodynamic modulation, and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Vasopressin and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Vasopressin in 0.9% Sodium Chloride ... Pressyn Ar
Experimental
Matched Synonyms: … (2R,3R,4S)-2,3,4-Trihydroxy-5-(hydroxyamino)-5-oxopentyl dihydrogen phosphate
Matched Name: … 5-phospho-D-arabinohydroxamic acid
Matched Iupac: … [(2R,3R,4S)-2,3,4-trihydroxy-4-(hydroxycarbamoyl)butoxy]phosphonic acid
Ambroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. The substance is a mucoactive drug with several properties including secretolytic and secretomotoric actions that restore the physiological clearance mechanisms of the...
Approved
Investigational
Matched Description: … its transport and in providing protection against infection and irritating agents. ... The substance is a mucoactive drug with several properties including secretolytic and secretomotoric ... It stimulates synthesis and release of surfactant by type II pneumocytes. …
Matched Mixtures name: … AMBROXOL 7.5MG + CLEMBUTEROL 5µG/5ML ... ETOLEX 7.5 - 5.0 ... AMBROXOL 15 MG+ CLENBUTEROL 10 MCG /5 ML …
Matched Salts name: … Ambroxol hydrochloride
Matched Categories: … Cough and Cold Preparations ... clenbuterol and ambroxol …
Matched Products: … AMBROXOL HYDROCHLORIDE ... AMBROXOLHCL AL 30MG/5ML ... AMBROXOL AL 15MG/5ML SAFT …
Tiaprofenic acid is a non-steroidal anti-inflammatory drug employed in the treatment of pain, particularly arthritis pain. It belongs to the arylpropionic acid (profen) group of nonsteroidal anti-inflammatory drugs (NSAIDs).
Approved
Matched Synonyms: … 2-(5-Benzoyl-thiophen-2-yl)-propionic acid ... 5-benzoyl-α-methyl-2-thiopheneacetic acid ... 5-benzoyl-α-methylthiophene-2-acetic acid
Matched Name: … Tiaprofenic acid
Matched Iupac: … 2-(5-benzoylthiophen-2-yl)propanoic acid
Matched Description: … Tiaprofenic acid is a non-steroidal anti-inflammatory drug employed in the treatment of pain, particularly ... It belongs to the _arylpropionic acid_ (profen) group of nonsteroidal anti-inflammatory drugs (NSAIDs …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Acyclic ... Fatty Acids ... Carboxylic Acids
Matched Products: … Teva-tiaprofenic Acid ... Apo-tiaprofenic Tablets-200mg ... Apo-tiaprofenic Tablets -300mg …
Displaying drugs 776 - 800 of 5394 in total