Displaying drugs 801 - 825 of 1126 in total
Valproic acid
Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in 1881 by Beverly S. Burton. It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century. In 1963, a serendipitous discovery was made by George Carraz during his investigations into...
Approved
Investigational
Matched Description: … Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in ... [A178051] It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for ... It is currently a compound of interest in the field of oncology for its anti-proliferative effects and …
Matched Products: … VALPRO BETA 150 ... VALPRO BETA 300 ... VALPRO BETA 600 …
Matched Products: … VALPRO BETA 150 ... VALPRO BETA 300 ... VALPRO BETA 600 …
Entecavir
Entecavir is an oral antiviral drug used in the treatment of hepatitis B infection. It is marketed under the trade name Baraclude (BMS).
Entecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the manufacturer claims that it is more efficacious than previous agents...
Approved
Investigational
Matched Description: … Food and Drug Administration (FDA) in March 2005. ... Entecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the ... manufacturer claims that it is more efficacious than previous agents used to treat hepatitis B (lamivudine and …
Matched Categories: … Nucleosides and Nucleotides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors …
Matched Products: … ENTECAVIR BETA 1 MG ... ENTECAVIR BETA 0.5MG ... ENTECAVIR BETA 0.5 MG …
Matched Categories: … Nucleosides and Nucleotides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors …
Matched Products: … ENTECAVIR BETA 1 MG ... ENTECAVIR BETA 0.5MG ... ENTECAVIR BETA 0.5 MG …
Cysteamine
Cystinosis is a rare disease caused by mutations in the CTNS gene that encodes for cystinosin, a protein responsible for transporting cystine out of the cell lysosome. A defect in cystinosin function is followed by cystine accumulation throughout the body, especially the eyes and kidneys. Several preparations of cysteamine exist...
Approved
Investigational
Matched Synonyms: … beta-aminoethanethiol ... beta-Mercaptoethylamine …
Matched Description: … in cystinosin function is followed by cystine accumulation throughout the body, especially the eyes and ... preparations of cysteamine exist for the treatment of cystinosis manifestations, some in capsule form, and ... L15616] In particular, cystine deposits on the eye can cause significant discomfort throughout the day and …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids and Derivatives ... Sulfur Compounds …
Matched Description: … in cystinosin function is followed by cystine accumulation throughout the body, especially the eyes and ... preparations of cysteamine exist for the treatment of cystinosis manifestations, some in capsule form, and ... L15616] In particular, cystine deposits on the eye can cause significant discomfort throughout the day and …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids and Derivatives ... Sulfur Compounds …
2'-Deoxycytidine
Experimental
Investigational
Matched Synonyms: … 1-(2-deoxy-.beta.-d-ribofuranosyl)cytosine ... 4-amino-1-(2-deoxy-.beta.-d-erythro-pentofuranosyl)-2(1h)-pyrimidinone …
N4-Hydroxycytidine
N4-Hydroxyctidine, or EIDD-1931, is a ribonucleoside analog which induces mutations in RNA virions.[A193008,A193011] N4-hydroxycytidine was first described in the literature in 1980 as a potent mutagen of bacteria and phage. It has shown antiviral activity against Venezuelan equine encephalitis virus, and the human coronavirus HCoV-NL63 in vitro. N4-hydroxycytodine has been...
Experimental
Matched Synonyms: … beta-D-N-4-Hydroxycytidine ... Beta-D-N4-hydroxycytidine …
Matched Description: … in mice and human airway epithelial cells. ... A193011] N4-hydroxycytidine was first described in the literature in 1980 as a potent mutagen of bacteria and ... [A193023] It has shown antiviral activity against Venezuelan equine encephalitis virus,[A193008] and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Description: … in mice and human airway epithelial cells. ... A193011] N4-hydroxycytidine was first described in the literature in 1980 as a potent mutagen of bacteria and ... [A193023] It has shown antiviral activity against Venezuelan equine encephalitis virus,[A193008] and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Ribavirin
Producing a broad-spectrum activity against several RNA and DNA viruses, Ribavirin is a synthetic guanosine nucleoside and antiviral agent that interferes with the synthesis of viral mRNA. It is primarily indicated for use in treating hepatitis C and viral hemorrhagic fevers. HCV is a single-stranded RNA virus that is categorized...
Approved
Matched Synonyms: … 1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide ... 1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide …
Matched Description: … The dual therapy was administered for 48 weeks in patients with genotype 1, 4, 5, and 6, and 24 weeks ... in patients with genotype 2 and 3 [A19626]. ... nucleoside and antiviral agent that interferes with the synthesis of viral mRNA. …
Matched Mixtures name: … Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules) …
Matched Categories: … Nucleosides and Nucleotides ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Description: … The dual therapy was administered for 48 weeks in patients with genotype 1, 4, 5, and 6, and 24 weeks ... in patients with genotype 2 and 3 [A19626]. ... nucleoside and antiviral agent that interferes with the synthesis of viral mRNA. …
Matched Mixtures name: … Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules) …
Matched Categories: … Nucleosides and Nucleotides ... Nucleic Acids, Nucleotides, and Nucleosides …
Cefixime
Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Investigational
Matched Description: … [A262894,A263011 ,L49293] Cephalosporins are beta-lactam antibiotics and can be used to treat gram-positive ... , and meningitis. ... a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and …
Matched Categories: … cefixime and ornidazole ... cefixime and azithromycin ... Sulfur Compounds ... beta-Lactams ... beta Lactam Antibiotics …
Matched Products: … HELIXIM …
Matched Categories: … cefixime and ornidazole ... cefixime and azithromycin ... Sulfur Compounds ... beta-Lactams ... beta Lactam Antibiotics …
Matched Products: … HELIXIM …
(S)-3-phenyllactic acid
Experimental
Matched Synonyms: … L-beta-Phenyllactic acid ... alpha-hydroxy-beta-phenyl-propionic acid …
Polaprezinc
Polaprezinc is a chelated form of zinc and L-carnosine. It is a zinc-related medicine approved for the first time in Japan, which has been clinically used to treat gastric ulcers [L1307, L1308]. It was determined that polaprezinc may be effective in pressure ulcer treatment . A study in 2013 showed...
Experimental
Matched Synonyms: … beta-Alanyl-L-histidinato zinc …
Matched Description: … Polaprezinc is a chelated form of zinc and L-carnosine. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Polaprezinc is a chelated form of zinc and L-carnosine. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Dofetilide
Dofetilide is a class III antiarrhythmic agent that is approved by the Food and Drug Administration (FDA) for the maintenance of sinus rhythm in individuals prone to the formation of atrial fibrillation and flutter, and for the chemical cardioversion to sinus rhythm from atrial fibrillation and flutter.
Approved
Investigational
Matched Synonyms: … beta-((p-Methanesulfonamidophenethyl)methylamino)methanesulfono-p-phenetidide …
Matched Description: … flutter, and for the chemical cardioversion to sinus rhythm from atrial fibrillation and flutter. ... Dofetilide is a class III antiarrhythmic agent that is approved by the Food and Drug Administration ( ... FDA) for the maintenance of sinus rhythm in individuals prone to the formation of atrial fibrillation and …
Matched Categories: … Sulfur Compounds …
Matched Description: … flutter, and for the chemical cardioversion to sinus rhythm from atrial fibrillation and flutter. ... Dofetilide is a class III antiarrhythmic agent that is approved by the Food and Drug Administration ( ... FDA) for the maintenance of sinus rhythm in individuals prone to the formation of atrial fibrillation and …
Matched Categories: … Sulfur Compounds …
beta-D-galactose 6-phosphate
Experimental
Matched Synonyms: … beta-galactose-6-phosphate …
Matched Name: … beta-D-galactose 6-phosphate …
Matched Name: … beta-D-galactose 6-phosphate …
6-o-Capryloylsucrose
Experimental
Matched Synonyms: … alpha-D-Glucopyranoside, 6-O-(1-oxooctyl)-beta-D-fructofuranosyl …
(3S)-3-methyl-D-aspartic acid
Experimental
Investigational
Matched Synonyms: … 3-methyl-beta-D-aspartic acid …
Beta-D-Glucopyranose Spirohydantoin
Experimental
Matched Name: … Beta-D-Glucopyranose Spirohydantoin …
beta-(1->4)-galactotriose
Experimental
Matched Synonyms: … beta-1,4-galactotrioside …
Matched Name: … beta-(1->4)-galactotriose …
Matched Name: … beta-(1->4)-galactotriose …
ORTHONITROPHENYL-BETA-D-FUCOPYRANOSIDE
Experimental
Matched Name: … ORTHONITROPHENYL-BETA-D-FUCOPYRANOSIDE …
Sumatriptan
Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches.[L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines. Sumatriptan was granted FDA approval on 28 December 1992.
Approved
Investigational
Matched Description: … Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches ... [L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available …
Matched Mixtures name: … Sumatriptan and Naproxen Sodium ... Sumatriptan Succinate and Naproxen Sodium ... Sumatriptan and Naproxen Sodium …
Matched Categories: … Sulfur Compounds ... Genito Urinary System and Sex Hormones ... sumatriptan and naproxen ... Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Products: … SUMATRIPTAN BETA 50MG ... SUMATRIPTAN BETA 100MG …
Matched Mixtures name: … Sumatriptan and Naproxen Sodium ... Sumatriptan Succinate and Naproxen Sodium ... Sumatriptan and Naproxen Sodium …
Matched Categories: … Sulfur Compounds ... Genito Urinary System and Sex Hormones ... sumatriptan and naproxen ... Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Products: … SUMATRIPTAN BETA 50MG ... SUMATRIPTAN BETA 100MG …
Ambrisentan
Ambrisentan is an orally active selective type A endothelin receptor antagonist indicated for the treatment of pulmonary arterial hypertension. It is approved in Europe, Canada and the United States for use as a single agent to improve exercise ability and delay clinical worsening. In addition, it is approved in the...
Approved
Investigational
Matched Description: … Patients studied displayed symptoms and etiologies predominantly of WHO Functional Class II-III. ... ability and delay clinical worsening. ... It is approved in Europe, Canada and the United States for use as a single agent to improve exercise …
Matched Categories: … ambrisentan and tadalafil …
Matched Products: … AMBRISENTAN BETA 5 MG FTA ... AMBRISENTAN BETA 10 MG FTA …
Matched Categories: … ambrisentan and tadalafil …
Matched Products: … AMBRISENTAN BETA 5 MG FTA ... AMBRISENTAN BETA 10 MG FTA …
Cyproterone acetate
An anti-androgen that, in the form of its acetate (cyproterone acetate), also has progestational properties. It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females.
Approved
Investigational
Matched Description: … in combination with estrogen, for the therapy of severe acne and hirsutism in females. ... It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, …
Matched Categories: … Antiandrogens and Estrogens ... cyproterone and estrogen ... Combination Contraceptives (with Estrogen and derivatives) ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System …
Matched Products: … Andro - Diane 10 mg - Tabletten ... CYPROTERONACETAT BETA 50MG …
Matched Categories: … Antiandrogens and Estrogens ... cyproterone and estrogen ... Combination Contraceptives (with Estrogen and derivatives) ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System …
Matched Products: … Andro - Diane 10 mg - Tabletten ... CYPROTERONACETAT BETA 50MG …
Ohmefentanyl
Ohmefentanyl is an extremely potent opioid analgesic drug which selectively binds to the µ-opioid receptor. The Chinese have recorded ohmefentanyl as having a potency that is 6,300 times morphine. Ohmefentanyl is one of the most potent μ -receptor agonists known, comparable to super-potent opioids such as carfentanil and etorphine which...
Illicit
Matched Synonyms: … Beta-hydroxy-3-methylfentanyl …
Matched Description: … the most potent μ -receptor agonists known, comparable to super-potent opioids such as carfentanil and ... In mice, ohmefentanyl was 28 times more powerful than fentanyl and 6300 times more effective than morphine ... Ohmefentanyl has three stereogenic centers and hence, it can derive into eight stereoisomers, currently …
Matched Description: … the most potent μ -receptor agonists known, comparable to super-potent opioids such as carfentanil and ... In mice, ohmefentanyl was 28 times more powerful than fentanyl and 6300 times more effective than morphine ... Ohmefentanyl has three stereogenic centers and hence, it can derive into eight stereoisomers, currently …
Vestronidase alfa
Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that is a purified enzyme produced by recombinant DNA technology in a Chinese hamster ovary cell line. The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid sequence as...
Approved
Investigational
Matched Synonyms: … Recombinant human beta-glucuronidase …
Matched Description: … spleen, heart valve abnormalities, and narrowed airways which can lead to lung infections and trouble ... sequence as human beta-glucuronidase (GUS) [FDA Label]. ... The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Lysosomal beta Glucuronidase …
Matched Description: … spleen, heart valve abnormalities, and narrowed airways which can lead to lung infections and trouble ... sequence as human beta-glucuronidase (GUS) [FDA Label]. ... The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Lysosomal beta Glucuronidase …
Ribaxamase
Ribaxamase is under investigation in clinical trial NCT02563106 (A Study of SYN-004 for the Prevention of c.diff in Patients With a LRTI).
Investigational
Matched Synonyms: … .beta.-lactamase (synthetic bacillus licheniformis isoenzyme syn-004) …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Displaying drugs 801 - 825 of 1126 in total