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Displaying drugs 801 - 825 of 5460 in total
Imidazole derivative anesthetic and hypnotic with little effect on blood gases, ventilation, or the cardiovascular system. It has been proposed as an induction anesthetic.
Approved
Matched Synonyms: … (R)-1-(1-phenylethyl)-1H-imidazole-5-carboxylic acid ethyl ester ... (R)-(+)-1-(α-methylbenzyl)imidazole-5-carboxylic acid ethyl ester ... 3-((R)-1-Phenyl-ethyl)-3H-imidazole-4-carboxylic acid ethyl ester …
Matched Iupac: … ethyl 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate …
Matched Description: … Imidazole derivative anesthetic and hypnotic with little effect on blood gases, ventilation, or the cardiovascular ... It has been proposed as an induction anesthetic. …
Matched Categories: … Hypnotics and Sedatives ... Heterocyclic Compounds, 1-Ring ... Drugs that are Mainly Renally Excreted …
Matched Products: … ETOMIDATE-LIPURO INJECTION 20 mg/10 ml ... HYPNOMIDATE 2 MG /10 ML AMPUL, 5 ADET ... ETOMIDE LIPURO 20MG/10ML IV ENJEKSIYONLUK EMULSIYON ICEREN AMPUL, 10 ADET …
Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
Approved
Vet approved
Matched Synonyms: … AP ... Ampicillin acid ... D-(−)-6-(α-aminophenylacetamido)penicillanic acid
Matched Iupac: … carboxylic acid ... (2S,5R,6R)-6-[(2R)-2-amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2- …
Matched Description: … Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum …
Matched Mixtures name: … Ampicillin and Sulbactam ... Ampicillin and Sulbactam ... Ampicillin and Sulbactam …
Matched Categories: … Drugs that are Mainly Renally Excreted …
Matched Products: … Jaa Amp Tab 125mg ... Apo Ampi Liq 125mg/5ml ... Apo Ampi Liq 250mg/5ml …
Investigational
Matched Synonyms: … 4-((4-AMINO-3-(4-CYCLOHEXYLPIPERAZIN-1-YL)-9,10-DIOXO-9,10-DIHYDROANTHRACEN-1-YL)AMINO)BENZOIC ACID ... 4-{[4-Amino-3-(4-cyclohexylpiperazin-1-yl)-9,10-dioxo-9,10-dihydroanthracen-1-yl]amino}benzoic acid ... BENZOIC ACID, 4-((4-AMINO-3-(4-CYCLOHEXYL-1-PIPERAZINYL)-9,10-DIHYDRO-9,10-DIOXO-1-ANTHRACENYL)AMINO) …
Matched Iupac: … 4-{[4-amino-3-(4-cyclohexylpiperazin-1-yl)-9,10-dioxo-9,10-dihydroanthracen-1-yl]amino}benzoic acid
Fazpilodemab is under investigation in clinical trial NCT04171765 (A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of BFKB8488A Compared With Placebo in Participants With Non-alcoholic Steatohepatitis).
Investigational
Matched Synonyms: … immunoglobulin G1-kappa, anti-[Homo sapiens KLB (klotho beta, b-Klotho)] and anti-[Homo sapiens FGFR1 ... anti-KLB (1-450) [VH (Homo sapiens IGHV3-66*01 ( ... (fibroblast growth factor receptor 1, FLT2, KAL2)], monoclonal antibody, bispecific; gamma1 heavy chain …
Matched Description: … Safety, and Pharmacokinetics of BFKB8488A Compared With Placebo in Participants With Non-alcoholic Steatohepatitis ... Fazpilodemab is under investigation in clinical trial NCT04171765 (A Study to Evaluate the Efficacy, …
Investigational
Matched Synonyms: … A-2205 free base ... M-(1-methyl-3-propyl-3-pyrrolidinyl)phenol ... Phenol, 3-(1-methyl-3-propyl-3-pyrrolidinyl)- …
Matched Iupac: … 3-(1-methyl-3-propylpyrrolidin-3-yl)phenol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Investigational
Matched Synonyms: … 1h-pyrazole-4-carboxylic acid, 1-(3-cyano-1-(1-methylethyl)-1h-indol-5-yl)- …
Bufexamac is a non-steroidal anti-inflammatory drug (NSAID) under the market name Droxaryl, Malipuran, Paraderm and Parfenac. It is typically administered topically for the treatment of subacute and chronic eczema of the skin, including atopic eczema and other inflammatory dermatoses, as well as sunburn and other minor burns, and itching. It...
Approved
Withdrawn
Matched Synonyms: … Bufexamic acid ... 4-Butoxyphenylacetohydroxamic acid ... 2-(p-Butoxyphenyl)-acetohydroxamic acid
Matched Description: … and itching. ... including atopic eczema and other inflammatory dermatoses, as well as sunburn and other minor burns, ... , Paraderm and Parfenac. …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Hydroxy Acids
Pemlimogene merolisbac is under investigation in clinical trial NCT03371381 (An Efficacy and Safety Study of JNJ-64041757, a Live Attenuated Listeria Monocytogenes Immunotherapy, in Combination With Nivolumab Versus Nivolumab Monotherapy in Participants With Advanced Adenocarcinoma of the Lung).
Investigational
Matched Synonyms: … copies of a 21 amino acid fr ... fusion protein comprising the n-terminal 100 amino acids of the lm acta protein (actan100), 5 tandem ... live-attenuated double-deleted (ladd) strain of listeria monocytogenes (lm .delta.acta/.delta.inlb) expressing a
Matched Description: … Pemlimogene merolisbac is under investigation in clinical trial NCT03371381 (An Efficacy and Safety Study ... of JNJ-64041757, a Live Attenuated Listeria Monocytogenes Immunotherapy, in Combination With Nivolumab …
Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and -resistant Staphylococcus aureus (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE).[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked...
Approved
Investigational
Matched Iupac: … -2-[(2S)-2-decanamido-3-(1H-indol-3-yl)propanamido]propanamido]propanoic acid ... (3S)-3-{[(3S,6S,9R,15S,18R,21S,24S,30S,31R)-3-[2-(2-aminophenyl)-2-oxoethyl]-24-(3-aminopropyl)-15,21 ... -decaoxo-1-oxa-4,7,10,13,16,19,22,25,28-nonaazacyclohentriacontan-30-yl]carbamoyl}-3-[(2R)-3-carbamoyl ... -bis(carboxymethyl)-6-[(2R)-1-carboxypropan-2-yl]-9-(hydroxymethyl)-18,31-dimethyl-2,5,8,11,14,17,20,23,26,29 …
Matched Description: … and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked ring and the N-terminal ... [A231379] Daptomycin was approved by the FDA on September 12, 2003, and is marketed under the name ... bacteria, including methicillin-susceptible and -resistant _Staphylococcus aureus_ (MSSA/MRSA) and vancomycin-resistant …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Drugs that are Mainly Renally Excreted …
Matched Products: … CUBICIN® 350 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... XAPTO 350 MG ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET ... XAPTO 500 MG ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET …
2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a is under investigation in clinical trial NCT01668823 (Photodynamic Therapy in Treating Patients With Lung Cancer).
Investigational
Matched Synonyms: … 3-PHORBINEPROPANOIC ACID, 14-ETHYL-9-(1-(HEXYLOXY)ETHYL)-4,8,13,18-TETRAMETHYL-20-OXO-, (3S,4S)- …
Matched Name: … 2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a
Matched Iupac: … 22-yl]propanoic acid ... 3-[(21S,22S)-11-ethyl-16-[1-(hexyloxy)ethyl]-12,17,21,26-tetramethyl-4-oxo-7,23,24,25-tetraazahexacyclo ... [18.2.1.1^{5,8}.1^{10,13}.1^{15,18}.0^{2,6}]hexacosa-1(23),2(6),5(26),8,10(25),11,13,15,17,19-decaen- …
Matched Description: … 2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a is under investigation in clinical trial NCT01668823 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Dezapelisib is under investigation in clinical trial NCT02456675 (INCB040093 and INCB040093 Combined With Itacitinib (INCB039110) in Relapsed/refractory Hodgkin Lymphoma).
Investigational
Matched Synonyms: … 6-(3-fluorophenyl)-3-methyl-7-[(1S)-1-(7H-purin-6-ylamino)ethyl]-[1,3]thiazolo[3,2-a]pyrimidin-5-one …
Matched Iupac: … 6-(3-fluorophenyl)-3-methyl-7-[(1S)-1-[(9H-purin-6-yl)amino]ethyl]-5H-[1,3]thiazolo[3,2-a]pyrimidin-5 …
Matched Description: … Dezapelisib is under investigation in clinical trial NCT02456675 (INCB040093 and INCB040093 Combined …
EW-A-401 is a circle of genetic material (plasmid DNA) that instructs the body to produce a genetically-engineered transcription factor, a protein that regulates expression of genes. This specific transcription factor has been shown in animal studies to increase expression of the VEGF-A gene, and to promote the growth of new...
Investigational
Matched Synonyms: … EW-A-401 DNA Plasmid Vector …
Matched Name: … EW-A-401 …
Matched Description: … gene, and to promote the growth of new blood vessels. ... EW-A-401 is a circle of genetic material (plasmid DNA) that instructs the body to produce a genetically-engineered ... transcription factor, a protein that regulates expression of genes. …
Ginsenosides are a class of steroid glycosides, and triterpene saponins, found exclusively in the plant genus Panax (ginseng). Ginsenosides have been the target of research, as they are viewed as the active compounds behind the claims of ginseng's efficacy. Because ginsenosides appear to affect multiple pathways, their effects are complex...
Nutraceutical
Matched Synonyms: … Panaxoside A ... Ginsenoside A2
Matched Iupac: … (2S,3R,4S,5S,6R)-2-{[(2S)-2-[(1R,2R,5S,7R,8S,10R,11R,14S,15R,16R)-5,16-dihydroxy-2,6,6,10,11-pentamethyl ... 3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecan-14
Matched Description: … Ginsenosides are a class of steroid glycosides, and triterpene saponins, found exclusively in the plant ... Because ginsenosides appear to affect multiple pathways, their effects are complex and difficult to isolate ... It improves spatial learning and increase hippocampal synaptophysin level in mice, plus demonstrates …
Viomycin is a tuberactinomycin antibiotic that was used to treat Mycobacterium tuberculosis until it was replaced by the less toxic capreomycin. These drugs bind RNA in bacterial ribosomes and inhibit protein synthesis. Viomycin was derived from the actinomycete Streptomyces puniceus.
Approved
Matched Synonyms: … Vinacetin A
Matched Iupac: … (3S)-3,6-diamino-N-[(3S,6Z,9S,12S,15S)-6-[(carbamoylamino)methylidene]-3-[(4R,6S)-6-hydroxy-2-imino-1,3 ... -diazinan-4-yl]-9,12-bis(hydroxymethyl)-2,5,8,11,14-pentaoxo-1,4,7,10,13-pentaazacyclohexadecan-15-yl …
Matched Description: … These drugs bind RNA in bacterial ribosomes and inhibit protein synthesis. ... Viomycin is a tuberactinomycin antibiotic that was used to treat Mycobacterium tuberculosis until it …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Dinitolmide is a fodder additive for prophylaxis against coccidiosis infections in poultry.
Experimental
Vet approved
Matched Synonyms: … Coccidine A
Matched Description: … Dinitolmide is a fodder additive for prophylaxis against coccidiosis infections in poultry. …
Matched Categories: … Benzamides and benzamide derivatives ... Acids, Carbocyclic ... Carboxylic Acids
A polyether antibiotic which affects ion transport and ATPase activity in mitochondria. It is produced by Streptomyces hygroscopicus. (From Merck Index, 11th ed)
Experimental
Matched Synonyms: … Polyetherin A
Matched Iupac: … [4.5]decan-7-yl]methyl}-3-methyloxan-2-yl]propanoic acid ... )-3,5-dimethyloxan-2-yl]-2,3'-dimethyl-[2,2'-bioxolan]-5-yl]-9-methoxy-2,4,10-trimethyl-1,6-dioxaspiro ... (2R)-2-[(2R,3S,6R)-6-{[(2S,4R,5R,7R,9R,10R)-2-[(2S,2'R,3'S,5R,5'R)-5'-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl …
Matched Description: … A polyether antibiotic which affects ion transport and ATPase activity in mitochondria. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Compounds used in a research, industrial, or household setting …
Approved
Matched Synonyms: … Recombinant haemagglutinin protein-strain A (H3N2) …
Matched Name: … Influenza A virus subtype H3N2 haemagglutinin, recombinant …
Lonidamine (LND) is a drug that interferes with energy metabolism of cancer cells, principally inhibiting aerobic glycolytic activity, by its effect on mitochondrially-bound hexokinase (HK). In such way LND could impair energy-requiring processes, as recovery from potentially lethal damage, induced by radiation treatment and by some cytotoxic drugs.
Investigational
Matched Synonyms: … 1-(2,4-dichlorbenzyl)-indazole-3-carboxylic acid ... diclondazolic acid
Matched Iupac: … 1-[(2,4-dichlorophenyl)methyl]-1H-indazole-3-carboxylic acid
Matched Description: … induced by radiation treatment and by some cytotoxic drugs. ... Lonidamine (LND) is a drug that interferes with energy metabolism of cancer cells, principally inhibiting ... In such way LND could impair energy-requiring processes, as recovery from potentially lethal damage, …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Heterocyclic Compounds, 1-Ring …
Nitazoxanide belongs to the class of drugs known as thiazolides. Nitazoxanide (NTZ) is a broad-spectrum anti-infective drug that markedly modulates the survival, growth, and proliferation of a range of extracellular and intracellular protozoa, helminths, anaerobic and microaerophilic bacteria, in addition to viruses. This drug is effective in the treatment of...
Approved
Investigational
Vet approved
Matched Iupac: … 2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl acetate …
Matched Description: … , and proliferation of a range of extracellular and intracellular protozoa, helminths, anaerobic and ... in healthy (not immunosuppressed) adults and children and may also be considered in the treatment of ... the replication of several RNA and DNA viruses [A31977]. …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Heterocyclic Compounds, 1-Ring …
Matched Products: … JOINTAX® 100 MG/5 ML POLVO PARA RECONSTITUIR A SUSPENSIÓN ORAL ... TIDAX® 100 MG/5ML POLVO PARA RECONSTITUIR A SUSPENSION ORAL ... FLUPAR 100 MG/ 5 ML POLVO PARA RECONSTITUIR A SUSPENSIÓN ORAL …
Bexarotene (Targretin) is an antineoplastic agent indicated by the FDA for Cutaneous T cell lymphoma. It has been used off-label for lung cancer, breast cancer, and Kaposi's sarcoma.
Approved
Investigational
Matched Synonyms: … 4-[1-(3,5,5,8,8-pentamethyltetralin-2-yl)ethenyl]benzoic acid ... p-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)vinyl)benzoic acid ... 4-[1-(5,6,7,8,-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphtalenyl)ethenyl]benzoic acid
Matched Iupac: … 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzoic acid
Matched Description: … It has been used off-label for lung cancer, breast cancer, and Kaposi's sarcoma. ... Bexarotene (Targretin) is an antineoplastic agent indicated by the FDA for Cutaneous T cell lymphoma. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Compounds used in a research, industrial, or household setting …
Matched Products: … BEKSAR %1 JEL, 60 GRAM ... BEXATEN %1 JEL, 60 GRAM ... BEXGRATIN 75 MG YUMUŞAK KAPSÜL ,100 YUMUŞAK KAPSÜL …
Experimental
Matched Synonyms: … 2,3-Dimercaptopropanesulfonic acid ... 2,3-Dimercapto-1-propane sulfonate ... 2,3-Dimercaptopropan-1-sulfonsaeure …
Matched Name: … 2,3-Dimercapto-1-propanesulfonic acid
Matched Iupac: … 2,3-disulfanylpropane-1-sulfonic acid
Matched Categories: … Compounds used in a research, industrial, or household setting …
Cyanocobalamin Co-60 is an analog of Vitamin B12 labeled with Co60. Cyanocobalamin Co-60 was used for the diagnosis of pernicious anemia, but now it is withdrawn from the market in the US for unknown reasons.
Approved
Withdrawn
Matched Synonyms: … Vitamin B12 - 60Co …
Matched Iupac: … (60Co)cobalt(3+) (2R,3S,4S,6Z,8S,9S,11Z,14S,16Z,18R,19R)-4,9,14-tris(2-carbamoylethyl)-3,8,19-tris(carbamoylmethyl ... )-18-(2-{[(2R)-2-{[(2R,3S,4R,5S)-5-(5,6-dimethyl-1H-1,3-benzodiazol-1-yl)-4-hydroxy-2-(hydroxymethyl) ... {7,10}.1^{12,15}]tricosa-5(23),6,10(22),11,15(21),16-hexaen-20-ide iminomethanide ... propyl]carbamoyl}ethyl)-2,3,6,8,13,13,16,18-octamethyl-20,21,22,23-tetraazapentacyclo[15.2.1.1^{2,5}.1^ …
Matched Description: … Cyanocobalamin Co-60 is an analog of Vitamin B12 labeled with Co60. …
Fluciclovine is a [18F]-tagged synthetic analog of the amino acid L-leucine. It presents excellent diagnostic properties to be used in positron emission tomography (PET) imaging. The structure of fluciclovine allows it to be uptaken by the tumoral cells by its amino acid transporter without incorporating in the metabolism within the...
Approved
Matched Synonyms: … (1R,3R)-1-amino-3(18F)fluorocyclobutane-1-carboxylic acid ... Anti-1-amino-3-(18F)fluorocyclobutane-1-carboxylic acid ... (18F)FACBC …
Matched Name: … Fluciclovine (18F) …
Matched Iupac: … (1r,3r)-1-amino-3-(¹⁸F)fluorocyclobutane-1-carboxylic acid
Matched Description: … Fluciclovine is a [18F]-tagged synthetic analog of the amino acid L-leucine. ... [A31385] Fluciclovine was developed by Blue Earth Diagnostics, Ltd. and FDA approved in May 27, 2016. ... [A31384] The structure of fluciclovine allows it to be uptaken by the tumoral cells by its amino acid
Matched Categories: … fluciclovine (18F) …
Investigational
Matched Synonyms: … Arsenenous acid, sodium salt (1:1) ... Arsenious acid, sodium salt ... Arsenious acid, monosodium salt …
A parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia.
Approved
Matched Synonyms: … 1-hydroxy-α-phenylcyclopentaneacetic acid 2-(dimethylamino)ethyl ester ... α-(1-hydroxycyclopentyl)benzeneacetic acid 2-(dimethylamino)ethyl ester ... 2-phenyl-2-(1-hydroxycyclopentyl)ethanoic acid β-(dimethylamino)ethyl ester …
Matched Iupac: … 2-(dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate …
Matched Description: … A parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia. …
Matched Salts cas: … 5870-29-1
Matched Categories: … Mydriatics and Cycloplegics ... Acids, Carbocyclic ... Carboxylic Acids
Matched Products: … CICLOPENTOLATO AL 1 % ... Ak-pentolate ... CYCLON 1% …
Displaying drugs 801 - 825 of 5460 in total