Displaying drugs 8226 - 8250 of 9438 in total
GSK-356278
Gsk356278 has been used in trials studying the treatment and basic science of Anxiety Disorders, Huntington Disease, Depressive Disorder, Huntingtons Disease, and Depressive Disorder, Major, among others.
Investigational
Matched Iupac: … 5-{5-[(2,4-dimethyl-1,3-thiazol-5-yl)methyl]-1,3,4-oxadiazol-2-yl}-1-ethyl-N-(oxan-4-yl)-1H-pyrazolo[ ... 3,4-b]pyridin-4-amine …
Lometrexol
Lometrexol has been used in trials studying the treatment of Lung Cancer, Drug/Agent Toxicity by Tissue/Organ, and Unspecified Adult Solid Tumor, Protocol Specific.
Investigational
Matched Iupac: … (2S)-2-[(4-{2-[(6R)-2-amino-4-oxo-1H,4H,5H,6H,7H,8H-pyrido[2,3-d]pyrimidin-6-yl]ethyl}phenyl)formamido …
Serlopitant
Serlopitant has been investigated for the treatment of Prurigo Nodularis.
Investigational
Matched Iupac: … 3-[(3aR,4R,5S,7aS)-5-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-4-(4-fluorophenyl)-octahydro-1H-isoindol …
Parsaclisib
Parsaclisib is under investigation in clinical trial NCT03126019 (An Open-Label Study of Parsaclisib in Relapsed or Refractory Follicular Lymphoma (CITADEL-203)).
Investigational
Matched Iupac: … (4R)-4-{3-[(1S)-1-{4-amino-3-methyl-1H-pyrazolo[3,4-d]pyrimidin-1-yl}ethyl]-5-chloro-2-ethoxy-6-fluorophenyl …
Janagliflozin
Janagliflozin is under investigation in clinical trial NCT03851432 (Janagliflozin Treat Type 2 Diabetes Mellitus (T2DM) Inadequately Controlled With Metformin).
Investigational
Matched Iupac: … (2S,3R,4R,5S,6R)-2-[4-chloro-3-({4-[(1R,3s,5S)-bicyclo[3.1.0]hexan-3-yloxy]phenyl}methyl)phenyl]-6-(hydroxymethyl …
Nerandomilast
Investigational
Matched Iupac: … (5R)-2-[4-(5-chloropyrimidin-2-yl)piperidin-1-yl]-4-{[1-(hydroxymethyl)cyclobutyl]amino}-5H,6H,7H-thieno ... [3,2-d]pyrimidin-5-ium-5-olate …
Zoliflodacin
Zoliflodacin has been used in trials studying the basic science and treatment of Gonorrhoea.
Investigational
Matched Iupac: … (4'R,6'S,7'S)-17'-fluoro-4',6'-dimethyl-13'-[(4S)-4-methyl-2-oxo-1,3-oxazolidin-3-yl]-5',15'-dioxa-2' …
Peridinin
Experimental
Matched Iupac: … ]heptan-1-yl]ethenyl}-5-oxo-2,5-dihydrofuran-2-ylidene]-3,10-dimethylundeca-1,3,5,7,9-pentaen-1-ylidene ... (1S,3R)-3-hydroxy-4-[(3E,5E,7E,9E)-11-[(2Z)-4-{2-[(1S,4S,6R)-4-hydroxy-2,2,6-trimethyl-7-oxabicyclo[4.1.0 …
Relacatib
Investigational
Matched Iupac: … -4-yl]pentanamide ... (2S)-2-[(1-benzofuran-2-yl)formamido]-4-methyl-N-[(4S,7R)-7-methyl-3-oxo-1-(pyridine-2-sulfonyl)azepan …
Afuresertib
Afuresertib has been used in trials studying the treatment of Cancer and Neoplasms, Haematologic.
Investigational
Matched Iupac: … N-[(2S)-1-amino-3-(3-fluorophenyl)propan-2-yl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene …
Pevonedistat
Pevonedistat has been used in trials studying the treatment of Lymphoma, Solid Tumors, Multiple Myeloma, Hodgkin Lymphoma, and Metastatic Melanoma, among others.
Investigational
Matched Iupac: … [(1S,2S,4R)-4-(4-{[(1S)-2,3-dihydro-1H-inden-1-yl]amino}-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl …
Matched Salts cas: … 1160295-21-5 …
Matched Salts cas: … 1160295-21-5 …
Vosaroxin
Vosaroxin is under investigation for the treatment of Leukemia, Myeloid, Acute.
Investigational
Matched Iupac: … 7-[(3S,4S)-3-methoxy-4-(methylamino)pyrrolidin-1-yl]-4-oxo-1-(1,3-thiazol-2-yl)-1,4-dihydro-1,8-naphthyridine …
LY-2874455
LY2874455 has been used in trials studying the treatment of Advanced Cancer.
Investigational
Matched Iupac: … 2-{4-[(E)-2-{5-[(1R)-1-(3,5-dichloropyridin-4-yl)ethoxy]-1H-indazol-3-yl}ethenyl]-1H-pyrazol-1-yl}ethan …
SAR-125844
SAR-125844 is under investigation in clinical trial NCT01391533 (Study of SAR125844 Single Agent Administered as Slow Intravenous Infusion in Adult Patients With Advanced Malignant Solid Tumors).
Investigational
Matched Iupac: … (morpholin-4-yl)ethyl]urea ... 3-(6-{[6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}-1,3-benzothiazol-2-yl)-1-[2- …
Nazartinib
Nazartinib is under investigation in clinical trial NCT03529084 (Phase III Study of Nazartinib (EGF816) Versus Erlotinib/gefitinib in First-line Locally Advanced / Metastatic NSCLC With EGFR Activating Mutations).
Investigational
Matched Iupac: … -4-carboxamide ... N-{7-chloro-1-[(3R)-1-[(2E)-4-(dimethylamino)but-2-enoyl]azepan-3-yl]-1H-1,3-benzodiazol-2-yl}-2-methylpyridine …
Almonertinib
Almonertinib is a third-generation EGFR tyrosine kinase inhibitor targeting EGFR-sensitizing and T790M resistance mutations.[A231859, A231864, A231869] It is being investigated against advanced or metastatic EGFR-mutated non-small cell lung cancer (NSCLC).
Investigational
Matched Iupac: … N-(5-{[4-(1-cyclopropyl-1H-indol-3-yl)pyrimidin-2-yl]amino}-2-{[2-(dimethylamino)ethyl](methyl)amino} ... -4-methoxyphenyl)prop-2-enamide …
C-peptide
C-peptide is under investigation in clinical trial NCT00278980 (Effect of C-peptide on Diabetic Peripheral Neuropathy).
Investigational
Matched Iupac: … ]propanamido]-4-carboxybutanamido]-3-carboxypropanamido]-4-methylpentanamido]-4-carbamoylbutanamido]- ... (4S)-4-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carboxybutanamido ... 3-methylbutanamido]acetamido}-4-carbamoylbutanamido]-3-methylbutanamido]-4-{[(1S)-1-[({[({2-[(2S)-2-[ ... ({[(1S)-1-[({[(1S)-1-{[(1S)-1-{[(2S)-4-carbamoyl-1-[(2S)-2-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(1S …
Ciluprevir
The compound, named BILN 2061, is an orally active inhibitor of the HCV NS3 protease and the first member of this new drug class to be tested in humans.
Investigational
Matched Iupac: … yl}quinolin-4-yl)oxy]-2,15-dioxo-3,16-diazatricyclo[14.3.0.0^{4,6}]nonadec-7-ene-4-carboxylic acid ... ,14S,18R)-14-{[(cyclopentyloxy)carbonyl]amino}-18-[(7-methoxy-2-{2-[(propan-2-yl)amino]-1,3-thiazol-4- …
Beta-hydroxyfentanyl
Experimental
Illicit
Matched Iupac: … N-[1-(2-hydroxy-2-phenylethyl)piperidin-4-yl]-N-phenylpropanamide …
Biopterin
A natural product that has been considered as a growth factor for some insects. [PubChem]
Experimental
Matched Iupac: … 2-amino-6-[(1S,2R)-1,2-dihydroxypropyl]-3,4-dihydropteridin-4-one …
L-erythro-7,8-dihydrobiopterin
7,8-Dihydrobiopterin is an inhibitor of the enzyme dihydroneopterin aldolase (DHNA), which catalyzes the conversion of 7,8-Dihydrobiopterin to 6-hydroxymethyl-7,8-dihydropterin and glycolaldehyde.
Experimental
Matched Iupac: … 2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-1,4,7,8-tetrahydropteridin-4-one …
Octylphenoxy polyethoxyethanol
Experimental
Matched Iupac: … 89-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72,75,78,81,84,87 …
Levopropoxyphene
Levopropoxyphene is a stereoisomer of propoxyphene in the form of 2S, 3R enantiomer. It was sold as an antitussive, but it was removed from the market in the 70s. Levopropoxyphene was developed by Lilly and FDA approved on March 21st, 1962. This drug presented different dosages and it was administered...
Withdrawn
Matched Iupac: … (2R,3S)-4-(dimethylamino)-3-methyl-1,2-diphenylbutan-2-yl propanoate …
CYCLOHEXYL-NORSTATINE
Experimental
Matched Iupac: … propan-2-yl (2R,3S)-3-amino-4-cyclohexyl-2-hydroxybutanoate …
Decoquinate
Decoquinate is used in veterinary to delay the growth and reproduction of coccidian parasites.
Experimental
Vet approved
Matched Iupac: … ethyl 6-(decyloxy)-7-ethoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate …
Displaying drugs 8226 - 8250 of 9438 in total