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Displaying drugs 851 - 875 of 959 in total

Andecaliximab

Andecaliximab is a monoclonal antibody directed against matrix metallopeptidase 9 (MMP9). Andecaliximab is under investigation in clinical trial NCT03631836 (Phase I Study of Monoclonal Antibondy (GS) 5745, an Matix Metalloproteinase 9 (MMP9) Mab Inhibitor, in Combination With Bevacizumab in Patients With Recurrent Glioblastoma).
Investigational
Matched Synonyms: … with human-mus musculus monoclonal gs-5745 light chain, dimer ... Immunoglobulin g4, anti-(human gelatinase b) (human-mus musculus monoclonal gs-5745 heavy chain), disulfide …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Docaravimab

Investigational
Matched Synonyms: … musculus monoclonal .gamma.2-chain), disulfide with mus musculus monoclonal .kappa. ... , anti-(rabies virus strainera (evelyn-rockitniki-abelseth) glycoprotein ectodomain epitope g-iii), mus ... musculus monoclonal 62-71-3 .gamma.2b-chain), disulfide with mus musculus monoclonal 62-71-3 .kappa. …

Ulenistamab

Investigational
Matched Synonyms: … pbp1510 .gamma.1-chain), disulfide with human-mus musculus monoclonal pbp1510 .kappa. ... Immunoglobulin g1, anti-(human pancreatic adenocarcinoma up-regulated factor) (human-mus musculus monoclonal …

Citicoline

Citicoline is a donor of choline in biosynthesis of choline-containing phosphoglycerides. It has been investigated for the treatment, supportive care, and diagnosis of Mania, Stroke, Hypomania, Cocaine Abuse, and Bipolar Disorder, among others.
Approved
Experimental
Matched Description: … , Cocaine Abuse, and Bipolar Disorder, among others. ... It has been investigated for the treatment, supportive care, and diagnosis of Mania, Stroke, Hypomania …
Matched Salts name: … Citicoline sodium …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … CITICOLINE SODIUM …

Coconut oil

Coconut oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Cocos Nucifera Seed Oil …
Matched Mixtures name: … Hair Loss and Scalp Moisturizing …

Povidone

Povidone, also known as polyvinylpyrrolidone (PVP) or polyvidone, is a synthetic water-soluble polymer made from the monomer N-vinylpyrrolidone used as a binder in many pharmaceutical tablets and lubricant in eye drops. It is also used in many technical applications with various roles as an adhesive, additive, and emulsifier. When in...
Approved
Withdrawn
Matched Description: … water-soluble polymer made from the monomer N-vinylpyrrolidone used as a binder in many pharmaceutical tablets and ... It is also used in many technical applications with various roles as an adhesive, additive, and emulsifier ... antiseptic properties where the iodine, a bactericidal component, mainly contributes to this effect, and …
Matched Mixtures name: … Redness reliever and Lubricant ... Rohto Sun and Sport ... Meijer Advanced Redness and Irritation Relief …
Matched Products: … iVizia Lubricant Eye for Severe Night Dry Eyes …

Temelimab

Temelimab is under investigation in clinical trial NCT02782858 (Clinical Trial Assessing the HERV-W Env Antagonist Gnbac1 for Efficacy in MS).
Investigational
Matched Synonyms: … Immunoglobulin G4, anti-(multiple sclerosis-associated retrovirus viral envelope protein) (human-mus ... musculus monoclonal gnbac1 heavy chain), disulfide with human-mus musculus monoclonal gnbac1 kappa-chain …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Fluconazole

Fluconazole, commonly known as Diflucan, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues. It was initially approved by the FDA in 1990. This drug is an azole antifungal, in the same drug family as ketoconazole and itraconazole. Fluconazole...
Approved
Investigational
Matched Description: … Fluconazole, commonly known as _Diflucan_, is an antifungal drug used for the treatment of both systemic and ... This drug is an _azole_ antifungal, in the same drug family as [ketoconazole] and [itraconazole]. …
Matched Categories: … Imidazole and Triazole Derivatives ... Triazole and tetrazole derivatives ... azithromycin, fluconazole and secnidazole ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Fluconazole in Sodium Chloride ... Fluconazole In Sodium Chloride Injection USP ... FLUCONAZOLEN CLORURO DE SODIO INYECCIÓN …

Epoprostenol

A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension.
Approved
Matched Description: … A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. ... The sodium salt has been also used to treat primary pulmonary hypertension. …
Matched Salts name: … Epoprostenol sodium …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … Epoprostenol Sodium …

Troglitazone

Troglitazone was withdrawn in 2000 due to risk of hepatotoxicity. It was superseded by pioglitazone and rosiglitazone.
Approved
Investigational
Withdrawn
Matched International brands: … Resulin …
Matched Description: … It was superseded by [pioglitazone] and [rosiglitazone]. …
Matched Categories: … Alimentary Tract and Metabolism …

Sofosbuvir

Sofosbuvir (tradename Sovaldi) is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the...
Approved
Matched International brands: … Resof …
Matched Description: … for its high replicative rate and genetic diversity [A19594]. ... count, and neuropsychiatric effects [A19635]. ... categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and …
Matched Mixtures name: … Ledipasvir and Sofosbuvir ... Sofosbuvir and Velpatasvir …
Matched Categories: … sofosbuvir and ledipasvir ... sofosbuvir and velpatasvir ... Nucleic Acids, Nucleotides, and Nucleosides ... sofosbuvir, velpatasvir and voxilaprevir …

Gentamicin

Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from Micromonospora purpurea in 1963. It is one of the most frequently prescribed aminoglycosides due to its spectrum of activity, low cost, and availability.[A234339,A234354] Gentamicin is effective against both gram-positive and gram-negative organisms but is particularly useful for the treatment...
Approved
Vet approved
Matched Description: … Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from _Micromonospora purpurea ... is one of the most frequently prescribed aminoglycosides due to its spectrum of activity, low cost, and ... [A234339,A234354] Gentamicin is effective against both gram-positive and gram-negative organisms but …
Matched Mixtures name: … Gentamicin Sulfate In 0.9% Sodium Chloride Injection ... Garasone Ophthalmic and Otic Solution …
Matched Categories: … Ophthalmological and Otological Preparations …
Matched Products: … Gentamicin Sulfate In Sodium Chloride ... Gentamicin Sulfate in Sodium Chloride …

Montelukast

Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs.[L6301,L6304,L6307,L6310,L6325,L6328,L6331] Although capable of demonstrating effectiveness, the use of such LTRAs like montelukast is typically in addition to or...
Approved
Matched Description: … via millions of prescriptions annually and has since become available as a generic and as a brand name ... montelukast to elicit neuropsychiatric effects like agitation, hallucinations, suicidal behaviour, and ... [A178651] And although these kinds of effects are currently included in the official prescribing information …
Matched Salts name: … Montelukast sodium …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Montelukast Sodium ... Montelukast sodium ... MONTELUKAST SODIUM …

Serplulimab

Investigational
Matched Synonyms: … hlx10 .gamma.4-chain), disulfide with human-mus musculus monoclonal hlx10 .kappa. ... Immunoglobulin g4 (228-proline), anti-(human programmed cell death protein 1) (human-mus musculus monoclonal …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …

Dinutuximab

Dinutuximab is an IgG1 monoclonal human/mouse chimeric antibody against GD2, a disialoganglioside expressed on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted expression on normal tissues. It is composed of the variable heavy- and light-chain regions of the murine anti-GD2 mAb 14.18 and the constant regions...
Approved
Investigational
Matched Synonyms: … WITH HUMAN-MUS MUSCULUS MONOCLONAL CH14.18 LIGHT CHAIN, DIMER ... WITH HUMAN-MUS MUSCULUS MONOCLONAL CH14.18/CHO LIGHT CHAIN, DIMER ... IMMUNOGLOBULIN G1, ANTI-(GANGLIOSIDE GD2) (HUMAN-MUS MUSCULUS MONOCLONAL CH14.18 HEAVY CHAIN), DISULFIDE …
Matched Description: … Despite a high clinical response seen after first-line treatment, the complete eradication of neuroblastoma ... It is composed of the variable heavy- and light-chain regions of the murine anti-GD2 mAb 14.18 and the ... constant regions of human IgG1 heavy-chain and kappa light-chain. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …

Atibuclimab

Atibuclimab (IC14) is a chimeric CD14 antibody investigated for the treatment of patients with severe sepsis.
Investigational
Matched Synonyms: … WITH HUMAN-MUS MUSCULUS MONOCLONAL IC14 .KAPPA. ... IMMUNOGLOBULIN G4, ANTI-(HUMAN CD14 ANTIGEN) (HUMAN-MUS MUSCULUS MONOCLONAL IC14 .GAMMA.4-CHAIN), DISULFIDE …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Zilovertamab

Investigational
Matched Synonyms: … .gamma.1-chain), disulfide with human-mus musculus monoclonal uc-961 .kappa. ... Immunoglobulin g1, anti-(human receptor tyrosine kinase ror-1) (human-mus musculus monoclonal uc-961 …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Pyrimethamine

One of the folic acid antagonists that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis.
Approved
Investigational
Vet approved
Matched Synonyms: … Chloridyn ... Chloridine …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... artesunate, sulfadoxine and pyrimethamine ... artesunate, sulfalene and pyrimethamine …

Edetic acid

A chelating agent (chelating agents) that sequesters a variety of polyvalent cations. It is used in pharmaceutical manufacturing and as a food additive.
Approved
Vet approved
Matched Description: … It is used in pharmaceutical manufacturing and as a food additive. …
Matched Categories: … Diet, Food, and Nutrition …
Matched Products: … SODIO EDETATO MONICO ... SODIO EDETATO S.A.L.F. ... SODIO EDETATO GALENICA SENESE …

Ertapenem

Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. It was first authorized for use in the US in November 2001 and in Europe in April 2002. Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic bacteria, ertapenem is used to...
Approved
Investigational
Matched Description: … [A447] Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic ... [L14339] It was first authorized for use in the US in November 2001 and in Europe in April 2002. …
Matched Salts name: … Ertapenem sodium …
Matched Products: … Ertapenem Sodium …

Alendronic acid

Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Matched Description: … is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and …
Matched Salts name: … Alendronate sodium ... Alendronate sodium anhydrous …
Matched Categories: … Drugs Affecting Bone Structure and Mineralization ... alendronic acid and colecalciferol ... alendronic acid and alfacalcidol, sequential ... alendronic acid, calcium and colecalciferol, sequential …
Matched Products: … Alendronate Sodium ... Ag-alendronate Sodium ... Jamp Alendronate Sodium …

Hyoscyamine

Hyoscyamine is a tropane alkaloid and the levo-isomer of atropine. It is commonly extracted from plants in the Solanaceae or nightshade family. Research into the action of hyoscyamine in published literature dates back to 1826. Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic...
Approved
Matched Synonyms: … Hyoscyamin …
Matched Description: … Hyoscyamine is a tropane alkaloid and the levo-isomer of [atropine]. ... [A228713] Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic …
Matched Mixtures name: … Phenazopyridine Hydrochloride, Hyoscyamine Hydrobromide, and Butabarbital ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide …
Matched Categories: … Alimentary Tract and Metabolism ... Belladonna and Derivatives, Plain ... hyoscyamine and psycholeptics …

Otlertuzumab

Otlertuzumab is under investigation in clinical trial NCT01188681 (Safety and Efficacy Study of TRU-016 Plus Bendamustine vs. Bendamustine in Relapsed Chronic Lymphocytic Leukemia).
Investigational
Matched Synonyms: … Immunoglobulin, anti-(human cd antigen cd37) (synthetic human-mus musculus fragment tru-016), dimer …
Matched Description: … Otlertuzumab is under investigation in clinical trial NCT01188681 (Safety and Efficacy Study of TRU-016 …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Colistin

Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.
Approved
Matched Description: … It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Matched Products: … COLISTIMETATO SODICO ALTAN ... COLISTIMETATO SODICO NORIDEM ... COLISTIMETATO SODICO NORIDEM LTD. …

Ketoprofen

Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.
Approved
Vet approved
Matched Description: … Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and …
Matched Salts name: … Ketoprofen sodium …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Ketoprofen and isomer ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Matched Products: … OKI GOLA ... KELIS GOLA ... EUSPIDOL GOLA …
Displaying drugs 851 - 875 of 959 in total