Displaying drugs 851 - 875 of 1202 in total
Brilaroxazine
Brilaroxazine (RP5063) is an investigational atypical antipsychotic which is under development by Reviva Pharmaceuticals for the treatment of schizophrenia and schizoaffective disorder. Reviva Pharmaceuticals also intends to investigate RP5063 for the treatment of bipolar disorder, major depressive disorder, psychosis/agitation associated with Alzheimer's disease, Parkinson's disease psychosis, attention deficit hyperactivity disorder...
Investigational
Matched Synonyms: … 6-(4-(4-(2,3-Dichlorophenyl)-piperazin-1-yl)-butoxy)-2H-benzo(b)(1,4)oxazin-3(4H)-one …
Matched Description: … Pharmaceuticals for the treatment of schizophrenia and schizoaffective disorder. ... Alzheimer's disease, Parkinson's disease psychosis, attention deficit hyperactivity disorder (ADD/ADHD), and ... Brilaroxazine (RP5063) is an investigational atypical antipsychotic which is under development by Reviva …
Matched Description: … Pharmaceuticals for the treatment of schizophrenia and schizoaffective disorder. ... Alzheimer's disease, Parkinson's disease psychosis, attention deficit hyperactivity disorder (ADD/ADHD), and ... Brilaroxazine (RP5063) is an investigational atypical antipsychotic which is under development by Reviva …
Pentoxifylline
Pentoxifylline (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and also has both anti-oxidant and anti-inflammatory properties.[A226415, L30300] Although originally developed to treat intermittent claudication, a form of exertion-induced leg pain common in patients with peripheral arterial disease, PTX has been investigated for its possible...
Approved
Investigational
Matched International brands: … Bo Shu Te …
Matched Description: … A branded product, PENTOXIL, marketed by Upsher-Smith Laboratories, and generic forms marketed by Valeant ... also has both anti-oxidant and anti-inflammatory properties. ... (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and …
Matched Products: … Truemed Group LLC …
Matched Description: … A branded product, PENTOXIL, marketed by Upsher-Smith Laboratories, and generic forms marketed by Valeant ... also has both anti-oxidant and anti-inflammatory properties. ... (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and …
Matched Products: … Truemed Group LLC …
Gentamicin
Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from Micromonospora purpurea in 1963. It is one of the most frequently prescribed aminoglycosides due to its spectrum of activity, low cost, and availability.[A234339,A234354] Gentamicin is effective against both gram-positive and gram-negative organisms but is particularly useful for the treatment...
Approved
Vet approved
Matched Description: … [A234339,A234354] Gentamicin is effective against both gram-positive and gram-negative organisms but ... [A234359,A234364]
Although gentamicin is well-established and may be used in a variety of clinical ... Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from _Micromonospora purpurea …
Matched Mixtures name: … Garasone Ophthalmic and Otic Solution ... LANTAMICIN-B ... GENTASON B …
Matched Categories: … Ophthalmological and Otological Preparations …
Matched Products: … Truemed Group LLC ... GENTAMICINA B. BRAUN ... GENTAMICINA SOLFATO BIL …
Matched Mixtures name: … Garasone Ophthalmic and Otic Solution ... LANTAMICIN-B ... GENTASON B …
Matched Categories: … Ophthalmological and Otological Preparations …
Matched Products: … Truemed Group LLC ... GENTAMICINA B. BRAUN ... GENTAMICINA SOLFATO BIL …
Riociguat
Riociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for the treatment of patients with inoperable CTEPH (chronic thromboembolic pulmonary hypertension), or persistent/recurrent PH (pulmonary hypertension)...
Approved
Matched Synonyms: … Methyl N-[4,6-Diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-N-methyl-carbaminate …
Matched Iupac: … methyl N-(4,6-diamino-2-{1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl}pyrimidin-5-yl)-N-methylcarbamate …
Matched Description: … regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for ... Riociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other ... Riociguat is marketed under the brand Adempas® by Bayer HealthCare Pharmaceuticals. …
Matched Iupac: … methyl N-(4,6-diamino-2-{1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl}pyrimidin-5-yl)-N-methylcarbamate …
Matched Description: … regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for ... Riociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other ... Riociguat is marketed under the brand Adempas® by Bayer HealthCare Pharmaceuticals. …
Emavusertib
Investigational
Matched Synonyms: … 4-oxazolecarboxamide, n-(5-((3r)-3-hydroxy-1-pyrrolidinyl)-2-(4-morpholinyl)oxazolo(4,5-b)pyridin-6-yl …
Matched Iupac: … N-{5-[(3R)-3-hydroxypyrrolidin-1-yl]-2-(morpholin-4-yl)-[1,3]oxazolo[4,5-b]pyridin-6-yl}-2-(2-methylpyridin …
Matched Iupac: … N-{5-[(3R)-3-hydroxypyrrolidin-1-yl]-2-(morpholin-4-yl)-[1,3]oxazolo[4,5-b]pyridin-6-yl}-2-(2-methylpyridin …
2-acetylamino-2-deoxy-b-D-allopyranose
Experimental
Matched Name: … 2-acetylamino-2-deoxy-b-D-allopyranose …
Raloxifene
Raloxifene is a second generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation.[A4979,T28] Exhibiting tissue-specific effects distinct from estradiol, raloxifene is the first of the benzothiophene group of antiestrogens to be labelled a SERM....
Approved
Investigational
Matched Synonyms: … (2-(4-Hydroxyphenyl)-6-hydroxybenzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)methanone …
Matched Description: … However, due to the off-target actions by HRT, newer non-hormonal agents such as raloxifene and [tamoxifen ... of antiestrogens to be labelled a SERM. ... Exhibiting tissue-specific effects distinct from [estradiol], raloxifene is the first of the benzothiophene group …
Matched Categories: … Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … However, due to the off-target actions by HRT, newer non-hormonal agents such as raloxifene and [tamoxifen ... of antiestrogens to be labelled a SERM. ... Exhibiting tissue-specific effects distinct from [estradiol], raloxifene is the first of the benzothiophene group …
Matched Categories: … Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Gimatecan
Gimatecan is an orally available 7-t-butoxyiminomethyl-substituted lipophilic camptothecin derivative.
Investigational
Matched Synonyms: … (4S)-11-[(E)-(tert-butoxyimino)methyl]-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline ... (4S)-4-ethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1-H-pyrano[3',4':6,7]-indolizino-[1,2-b]-quinoline ... 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-11-carboxaldehyde, 4-ethyl-3,4,12,14-tetrahydro-4-hydroxy …
Amlodipine
Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers. Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and cardiac conduction abnormalities...
Approved
Matched Description: … Amlodipine is commonly used in the treatment of high blood pressure and angina. ... dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and ... Amlodipine has antioxidant properties and an ability to enhance the production of nitric oxide (NO), …
Matched Mixtures name: … Amlodipine Besylate and Benazepril Hydrochloride ... Amlodipine besylate and benazepril hydrochloride ... Amlodipine besylate and benazepril hydrochloride …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Angiotensin II Antagonists and Calcium Channel Blockers ... Calcium Channel Blockers and Diuretics ... Calcium-Regulating Hormones and Agents ... nebivolol and amlodipine …
Matched Products: … A-B VASK 5 ... A-B VASK 10 ... Bio-amlodipine …
Matched Mixtures name: … Amlodipine Besylate and Benazepril Hydrochloride ... Amlodipine besylate and benazepril hydrochloride ... Amlodipine besylate and benazepril hydrochloride …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Angiotensin II Antagonists and Calcium Channel Blockers ... Calcium Channel Blockers and Diuretics ... Calcium-Regulating Hormones and Agents ... nebivolol and amlodipine …
Matched Products: … A-B VASK 5 ... A-B VASK 10 ... Bio-amlodipine …
Talditercept alfa
Talditercept alfa is under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and Tolerability of RO7239361 in Ambulatory Boys With Duchenne Muscular Dystrophy).
Investigational
Matched Synonyms: … Bms-986089 (fully human anti-myostatin adnectin) ... -986089 fibronectin tenth type iii domain-derived), dimer ... Adnectin, anti-(human growth differentiation factor 8) (synthetic clone prd-1474 fibronectin type iii …
Matched Description: … under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and …
Matched Description: … under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and …
Palazestrant
Palazestrant is under investigation in clinical trial NCT06016738 (OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer).
Investigational
Matched Synonyms: … 2-methylpropyl)-3-methyl-1-{4-[(1-propylazetidin-3- yl)oxy]phenyl}-2,3,4,9-tetrahydro-1H-pyrido[3,4-b] ... 1H-Pyrido[3,4-b]indole, 2-(2-fluoro-2-methylpropyl)-2,3,4,9-tetrahydro-3-methyl-1-[4-[(1-propyl-3-azetidinyl …
Pirenzepine
An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also...
Approved
Matched Synonyms: … 11-((4-Methyl-1-piperazinyl)acetyl)-5,11-dihydro-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-one …
Matched Description: … It is generally well tolerated by patients. ... required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and ... It also potentiates the effect of other antiulcer agents such as cimetidine and ranitidine. …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Description: … It is generally well tolerated by patients. ... required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and ... It also potentiates the effect of other antiulcer agents such as cimetidine and ranitidine. …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
EP-0042
Investigational
Matched Synonyms: … 3H-IMIDAZO(4,5-B)PYRIDINE, 6-CHLORO-7-(4-((4-CHLOROPHENYL)METHYL)-1-PIPERAZINYL)-2-(1,3-DIMETHYL-1H-PYRAZOL …
Matched Iupac: … 1-[6-chloro-2-(1,3-dimethyl-1H-pyrazol-4-yl)-3H-imidazo[4,5-b]pyridin-7-yl]-4-[(4-chlorophenyl)methyl …
Matched Iupac: … 1-[6-chloro-2-(1,3-dimethyl-1H-pyrazol-4-yl)-3H-imidazo[4,5-b]pyridin-7-yl]-4-[(4-chlorophenyl)methyl …
Human papillomavirus type 18 L1 capsid protein residues 2-472 antigen
Approved
Investigational
Matched Name: … Human papillomavirus type 18 L1 capsid protein residues 2-472 antigen …
Trenbolone
Trenbolone, also known as trienolone or trienbolone, is a steroid used on livestock to increase muscle growth and appetite. To increase its effective half-life, trenbolone is administered as a prodrug as an ester conjugate such as trenbolone acetate, trenbolone enanthate, or trenbolone cyclohexylmethylcarbonate. Plasma lipases then cleave the ester group...
Vet approved
Matched Synonyms: … 17-b-Hydroxyestra-4,9,11-trien-3-one …
Matched Description: … , also known as trienolone or trienbolone, is a steroid used on livestock to increase muscle growth and ... Plasma lipases then cleave the ester group in the bloodstream leaving free trenbolone. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … , also known as trienolone or trienbolone, is a steroid used on livestock to increase muscle growth and ... Plasma lipases then cleave the ester group in the bloodstream leaving free trenbolone. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
6-PHENYL[5H]PYRROLO[2,3-B]PYRAZINE
Experimental
Matched Name: … 6-PHENYL[5H]PYRROLO[2,3-B]PYRAZINE …
Matched Iupac: … 4-{7-butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl}phenol …
Matched Iupac: … 4-{7-butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl}phenol …
Human botulinum neurotoxin A/B immune globulin
Infant botulism is a rare infectious disease occurring in infants in which Clostridium botulinum colonize the large intestine and being to produce botulinum neurotoxin directly in the gut. As these neurotoxins interfere with cholinergic nervous transmission, patients initially present with evident of loss of muscle tone (e.g. constipation, ptosis, feeding...
Approved
Matched Synonyms: … Botulism immune globulin intravenous (human) (BIG-IV) …
Matched Name: … Human botulinum neurotoxin A/B immune globulin …
Matched Description: … [L39834] It is produced and distributed by the Calfornia Department of Public Health's Infant Botulism ... Treatment and Prevention Program[L39829] and comprises IgG antibodies derived from pooled adult plasma ... infectious disease occurring in infants in which _Clostridium botulinum_ colonize the large intestine and …
Matched Name: … Human botulinum neurotoxin A/B immune globulin …
Matched Description: … [L39834] It is produced and distributed by the Calfornia Department of Public Health's Infant Botulism ... Treatment and Prevention Program[L39829] and comprises IgG antibodies derived from pooled adult plasma ... infectious disease occurring in infants in which _Clostridium botulinum_ colonize the large intestine and …
Typha latifolia pollen
Typha latifolia pollen is the pollen of the Typha latifolia plant. Typha latifolia pollen is mainly used in allergenic testing.
Approved
Matched Name: … Typha latifolia pollen …
Matched Description: … Typha latifolia pollen is the pollen of the Typha latifolia plant. ... Typha latifolia pollen is mainly used in allergenic testing. …
Matched Mixtures name: … Mixture of Twenty-Two Standardized and Non-Standardized Grasses …
Matched Description: … Typha latifolia pollen is the pollen of the Typha latifolia plant. ... Typha latifolia pollen is mainly used in allergenic testing. …
Matched Mixtures name: … Mixture of Twenty-Two Standardized and Non-Standardized Grasses …
Leflunomide
Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and pharmacologically very heterogeneous. Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999.
Approved
Investigational
Matched Description: … Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999. ... belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Leflunomide and metabolite …
Matched Products: … Truemed Group LLC …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Leflunomide and metabolite …
Matched Products: … Truemed Group LLC …
Tamatinib
Experimental
Investigational
Matched Synonyms: … 6-({5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}amino)-2,2-dimethyl-2H-pyrido[3,2-b][1,4 …
Matched Iupac: … -({5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}amino)-2,2-dimethyl-2H,3H,4H-pyrido[3,2-b] …
Matched Iupac: … -({5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}amino)-2,2-dimethyl-2H,3H,4H-pyrido[3,2-b] …
AZD-5153
Investigational
Matched Synonyms: … 2-piperazinone, 4-(2-(4-(1-(3-methoxy-1,2,4-triazolo(4,3-b)pyridazin-6-yl)-4-piperidinyl)phenoxy)ethyl …
Matched Iupac: … (3R)-4-{2-[4-(1-{3-methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperidin-4-yl)phenoxy]ethyl}-1,3-dimethylpiperazin …
Matched Iupac: … (3R)-4-{2-[4-(1-{3-methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperidin-4-yl)phenoxy]ethyl}-1,3-dimethylpiperazin …
Alteplase
Alteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent. It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots. In the absence of fibrin, the alteplase-mediated conversion of plasminogen is limited, thanks to the high affinity between alteplase and fibrin.[A252330,L43125] Alteplase...
Approved
Investigational
Matched Synonyms: … Plasminogen activator (human tissue-type protein moiety) …
Matched Description: … alteplase-mediated conversion of plasminogen is limited, thanks to the high affinity between alteplase and ... alteplase to manage AMI has decreased thanks to the availability of safer treatments such as angioplasty and ... thrombolytic agents derived from tissue plasminogen activator, such as [desmoteplase], [tenecteplase] and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Matched Description: … alteplase-mediated conversion of plasminogen is limited, thanks to the high affinity between alteplase and ... alteplase to manage AMI has decreased thanks to the availability of safer treatments such as angioplasty and ... thrombolytic agents derived from tissue plasminogen activator, such as [desmoteplase], [tenecteplase] and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Alectinib
Alectinib is a second generation oral drug that selectively inhibits the activity of anaplastic lymphoma kinase (ALK) tyrosine kinase. It is specifically used in the treatment of non-small cell lung cancer (NSCLC) expressing the ALK-EML4 (echinoderm microtubule-associated protein-like 4) fusion protein that causes proliferation of NSCLC cells. Inhibition of ALK...
Approved
Investigational
Matched Synonyms: … 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3- …
Matched Iupac: … 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-5H,6H,11H-benzo[b]carbazole-3-carbonitrile …
Matched Description: … Inhibition of ALK prevents phosphorylation and subsequent downstream activation of STAT3 and AKT resulting …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-5H,6H,11H-benzo[b]carbazole-3-carbonitrile …
Matched Description: … Inhibition of ALK prevents phosphorylation and subsequent downstream activation of STAT3 and AKT resulting …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Hydrocortisone butyrate
Approved
Vet approved
Matched Synonyms: … H-17-B …
Matched Categories: … Hydrocortisone and derivatives ... hydrocortisone butyrate and antiseptics ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Corticosteroids, Moderately Potent (Group II) …
Matched Categories: … Hydrocortisone and derivatives ... hydrocortisone butyrate and antiseptics ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Corticosteroids, Moderately Potent (Group II) …
Displaying drugs 851 - 875 of 1202 in total