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Displaying drugs 901 - 925 of 1133 in total

Deferasirox

Deferasirox is an iron chelator and the first oral medication FDA approved for chronic iron overload in patients receiving long term blood transfusions.
Approved
Investigational
Matched Description: … Deferasirox is an iron chelator and the first oral medication FDA approved for chronic iron overload …
Matched Products: … JADENU FILM COATED TABLET 90MG ... JADENU FILM COATED TABLET 180MG ... JADENU FILM COATED TABLET 360MG …

Daclatasvir

Daclatasvir is a direct-acting antiviral agent against Hepatitis C Virus (HCV) used for the treatment of chronic HCV genotype 1 and 3 infection. It is marketed under the name DAKLINZA and is contained in daily oral tablets as the hydrochloride salt form . Hepatitis C is an infectious liver disease...
Approved
Investigational
Matched Description: … Daclatasvir is shown to target both the cis- and trans-acting functions of NS5A and disrupts the function ... daclatasvir and [DB08934] therapy were 88% and 99%, respectively [FDA Label]. ... direct-acting antiviral agent against Hepatitis C Virus (HCV) used for the treatment of chronic HCV genotype 1 and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... daclatasvir, asunaprevir and beclabuvir …
Matched Products: … DAKLINZA 30 MG FILM KAPLI TABLET ,FILM KAPLI TABLET, 28 ADET ... DAKLINZA 60 MG FILM KAPLI TABLET ,FILM KAPLI TABLET, 28 ADET ... Daclavir 60mg Film Coated Tablet …

Ribociclib

Ribociclib is a selective cyclin-dependent kinase inhibitor, a class of drugs that help slow the progression of cancer by inhibiting two proteins called cyclin-dependent kinase 4 and 6 (CDK4/6). These proteins, when over-activated, can enable cancer cells to grow and divide too quickly. Targeting CDK4/6 with enhanced precision may play...
Approved
Investigational
Matched Description: … that help slow the progression of cancer by inhibiting two proteins called cyclin-dependent kinase 4 and ... These proteins, when over-activated, can enable cancer cells to grow and divide too quickly. ... FDA in March, 2017 as Kisqali. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … KISQALI FILM-COATED TABLET 200MG ... Kryxana 200mg Film-coated Tablets ... VALAMOR 200 MG FİLM KAPLI TABLET, 63 ADET …

Lercanidipine

Lercanidipine is a calcium channel blocker of the dihydropyridine class. It is sold under various commercial names including Zanidip.
Approved
Investigational
Matched Mixtures name: … ZANITEK 10 MG/10MG FILM TABLET,90 ADET ... ZANITEK 10 MG/10MG FILM TABLET, 30 ADET ... ZANITEK 20 MG/10MG FILM TABLET, 30 ADET …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... valsartan and lercanidipine ... enalapril and lercanidipine …
Matched Products: … ZANIDIP 10MG FILM COATED TABLETS ... Zanidip 20mg, film-coated tablet ... LERCADIP 10 MG FILM TABLET, 30 ADET …

Bosutinib

Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine kinase inhibitor indicated for chronic myelogenous leukemia (CML), specifically Philadelphia chromosome-positive (Ph+) CML. Philadelphia chromosome is a hallmark of CML due to the reciprocal translocation t(9;22)(q34;q11), resulting in a BCR-ABL fusion protein.[A6902,A261796,A261801] The first BCR-ABL inhibitor,...
Approved
Matched Description: … Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine ... BCR-ABL inhibitors like bosutinib inhibit most resistance-conferring BCR-ABL mutations except V299L and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … BOSULİF 500 MG FİLM KAPLI TABLET, 28 ADET ... BOSULİF 500 MG FİLM KAPLI TABLET, 30 ADET ... BOSULİF 100 MG FİLM KAPLI TABLET, 28 ADET …

Capmatinib

Capmatinib is a small molecule kinase inhibitor targeted against c-Met (a.k.a. hepatocyte growth factor receptor [HGFR]), a receptor tyrosine kinase that, in healthy humans, activates signaling cascades involved in organ regeneration and tissue repair. Aberrant c-Met activation - via mutations, amplification, and/or overexpression - is known to occur in many...
Approved
Investigational
Matched Description: … such as STAT3, PI3K/ATK, and RAS/MAPK. ... tyrosine kinase that, in healthy humans, activates signaling cascades involved in organ regeneration and ... [A199122] Aberrant c-Met activation - via mutations, amplification, and/or overexpression - is known …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … TABRECTA FILM-COATED TABLET 150mg ... Rahika 150mg Film-coated Tablet ... TABRECTA FILM-COATED TABLET 200mg …

Rilpivirine

Rilpivirine is non-nucleoside reverse transcriptase inhibitor (NNRTI) which is used for the treatment of HIV-1 infections in treatment-naive patients. It is a diarylpyrimidine derivative. The internal conformational flexibility of rilpivirine and the plasticity of it interacting binding site gives it a very high potency and reduces the chance of resistance...
Approved
Matched Description: … [A31329] The internal conformational flexibility of rilpivirine and the plasticity of it interacting ... [A31331] Rilpivirine was developed by Tilbotec, Inc. and FDA approved on May 20, 2011. ... binding site gives it a very high potency and reduces the chance of resistance compared to other NNRTI's …
Matched Mixtures name: … COMPLERA FILM-COATED TABLET 200MG/25MG/300MG ... ODEFSEY 200 MG/25 MG/25 MG FİLM KAPLI TABLET, 90 ADET ... ODEFSEY 200 MG/25 MG/25 MG FİLM KAPLI TABLET, 30 ADET …
Matched Categories: … dolutegravir and rilpivirine ... emtricitabine, tenofovir disoproxil and rilpivirine ... emtricitabine, tenofovir alafenamide and rilpivirine …
Matched Products: … EDURANT FILM-COATED TABLET 25 MG ... Edurant 25mg film-coated tablet ... EDURANT 25 MG FILM KAPLI TABLET, 30 ADET …

Lacosamide

Lacosamide is an antiepileptic drug used to treat seizures. As a chiral functionalized amino acid, it works by blocking slowly inactivating components of voltage-gated sodium currents. Lacosamide exhibits a stereoselective mode of interaction with sodium channels. Lacosamide was first approved by the European Commission in August 2008 and was later...
Approved
Matched Description: … [A262681] Lacosamide was first approved by the European Commission in August 2008 and was later approved …
Matched Products: … Mar-lacosamide ... VIMPAT 50 MG (FILM-COATED TABLETS) ... VIMPAT 100 MG (FILM-COATED TABLETS) …

Imatinib

Imatinib is a small molecule kinase inhibitor that revolutionized the treatment of cancer, particularly chronic myeloid leukemia, in 2001. It was deemed a "miracle drug" due to its clinical success, as oncologist Dr. Brian noted that "complete hematologic responses were observed in 53 of 54 patients with CML treated with...
Approved
Matched Description: … responses were observed in 53 of 54 patients with CML treated with a daily dosage of 300 mg or more and ... [L42220] Imatinib was approved on February 1st ,2001 by the FDA and November 7th, 2001 by the EMA …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Benzamides and benzamide derivatives …
Matched Products: … IMATIS 200 MG FILM TABLET,FILM TABLET, 60 ADET ... Imarem 100mg film-coated tablets ... Imarem 400mg film-coated tablets …

Paroxetine

Paroxetine is a selective serotonin reuptake inhibitor (SSRI) drug commonly known as Paxil. It has a variety of uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and symptoms of menopause, among others. It was approved by the FDA in the early 1990s and marketed by SmithKline...
Approved
Investigational
Matched Description: … of serotonin reuptake and has little effect on other neurotransmitters. ... uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and ... [T653] It was approved by the FDA in the early 1990s and marketed by SmithKline Beecham. …
Matched Products: … Mar-paroxetine ... PALUXON 20 MG FİLM TABLET, 14 ADET ... PALUXON 20 MG FİLM TABLET, 28 ADET …

Mycophenolate mofetil

Mycophenolate mofetil, also known as MMF or CellCept, is a prodrug of mycophenolic acid, and classified as a reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH). This drug is an immunosuppressant combined with drugs such as Cyclosporine and corticosteroids to prevent organ rejection after hepatic, renal, and cardiac transplants. It is...
Approved
Investigational
Matched Description: … Mycophenolate mofetil, also known as MMF or CellCept, is a prodrug of mycophenolic acid, and classified ... to prevent organ rejection after hepatic, renal, and cardiac transplants. ... [A180805] This drug is an immunosuppressant combined with drugs such as [Cyclosporine] and corticosteroids …
Matched Categories: … Mycophenolic Acid and Prodrugs …
Matched Products: … Mar-mycophenolate Mofetil ... MYFENAX FILM-COATED TABLETS 500MG ... TARBETAX 500 MG FILM TABLET, 150 ADET …

Tolterodine

Tolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.
Approved
Investigational
Matched Description: … Tolterodine acts on M2 and M3 subtypes of muscarinic receptors. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Matched Products: … TOLTEX 2 MG FILM TABLET, 28 ADET ... TOLTEX FİLM 1 MG TABLET , 28 ADET ... URIDYN 1 MG FILM TABLET ,28 ADET …

Canagliflozin

Canagliflozin, also known as Invokana, is a sodium-glucose cotransporter 2 (SGLT2) inhibitor used in the management of type 2 diabetes mellitus along with lifestyle changes including diet and exercise [FDA label]. It was initially approved by the FDA in 2013 for the management of diabetes and later approved in 2018...
Approved
Matched Description: … inhibitor used in the management of type 2 diabetes mellitus along with lifestyle changes including diet and ... It was initially approved by the FDA in 2013 for the management of diabetes and later approved in 2018 …
Matched Mixtures name: … FILM-COATED TABLETS 50 MG / 1000 MG ... FILM-COATED TABLETS 50 MG / 500 MG ... FILM-COATED TABLETS 150 MG / 500 MG …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and canagliflozin …
Matched Products: … FILM-COATED TABLETS 100 MG ... FILM-COATED TABLETS 300 MG ... Invokana 300mg Film-Coated Tablets …

Cefditoren

Cefditoren is an oral third-generation cephalosporin. It is commonly marketed under the trade name Spectracef by Cornerstone BioPharma.
Approved
Investigational
Matched Products: … CEFITEN 200 MG FILM TABLET, 10 ADET ... CEFITEN 400 MG FILM TABLET, 14 ADET ... CEFITEN 400 MG FILM TABLET, 20 ADET …

Axitinib

Axitinib is a second generation tyrosine kinase inhibitor that works by selectively inhibiting vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, VEGFR-3). Through this mechanism of action, axitinib blocks angiogenesis, tumour growth and metastases. It is reported to exhibit potency that is 50-450 times higher than that of the first generation...
Approved
Investigational
Matched Description: … [L6676] Through this mechanism of action, axitinib blocks angiogenesis, tumour growth and metastases. ... [A179398] It is most commonly marketed under the name Inlyta® and is available in oral formulations. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Benzamides and benzamide derivatives …
Matched Products: … Inlyta Film-coated Tablets 1mg ... Inlyta Film-coated Tablets 5mg ... INLYTA 3 MG FİLM KAPLI TABLET, 28 ADET …

Lorlatinib

Lorlatinib is a third-generation ALK tyrosine kinase inhibitor (TKI) for patients with ALK-positive metastatic non-small cell lung cancer which was first approved by the US FDA in November of 2018. It was subsequently approved by the EMA in 2019 for the treatment of select patients with previously treated advanced ALK-positive...
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Lorviqua 100 mg Film-Coated Tablets ... LORVIQUA FILM-COATED TABLET 25MG ... LORVIQUA FILM-COATED TABLET 100MG …

Nalmefene

Nalmefene, a 6-methylene analogue of naltrexone, is an opioid receptor antagonist. It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist at the kappa (κ)-opioid receptor. In Europe, nalmefene oral tablets are used to reduce alcohol consumption in adults with alcohol dependence. Nalmefene...
Approved
Investigational
Withdrawn
Matched Description: … [L40684] It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist …
Matched Products: … SELINCRO 18MG FILM KAPLI TABLET ,42 TABLET ... SELINCRO 18MG FILM KAPLI TABLET ,7 TABLET ... SELINCRO 18MG FILM KAPLI TABLET ,TABLET, 28 ADET …

Ertugliflozin

Ertugliflozin is a sodium-dependent glucose cotransporter-2 (SGLT2) inhibitor used to treat type II diabetes mellitus. It works to block glucose reabsorption from the glomerulus. Ertugliflozin was first approved by the FDA in December 2017.[A261951, L1132] It was also approved by the European Commission in March 2018.
Approved
Investigational
Matched Description: … [A261951, L1132] It was also approved by the European Commission in March 2018.[L48621] …
Matched Mixtures name: … Steglujan (Ertugliflozin 5mg/Sitagliptin 100mg) Film-Coated Tablets ... Steglujan (Ertugliflozin 15mg/Sitagliptin 100mg) Film-Coated Tablets ... Segluromet (Ertugliflozin 2.5mg/ Metformin 500mg) Film-Coated Tablet …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and ertugliflozin ... sitagliptin and ertugliflozin …
Matched Products: … STEGLATRO FILM-COATED TABLETS 5MG ... Steglatro 5mg Film-Coated Tablets ... STEGLATRO FILM-COATED TABLETS 15MG …

Ornidazole

Ornidazole has been used in trials studying the prevention of Elective Colorectal Surgery.
Investigational
Matched Mixtures name: … ORNISASIN 500 MG/500 MG FILM TABLET, 10 ADET ... ORNISASIN 500 MG/500 MG FILM TABLET, 20 ADET ... ORCIPOL 500 MG/500 MG FILM TABLET, 10 ADET …
Matched Categories: … Genito Urinary System and Sex Hormones ... Antiparasitic Products, Insecticides and Repellents ... ofloxacin and ornidazole ... cefixime and ornidazole ... levofloxacin and ornidazole …
Matched Products: … BITAZOL 250 MG FILM TABLET, 20 ADET ... ORNITOP 250 MG FILM TABLET, 20 ADET ... ORNITOP 500 MG FILM TABLET, 10 ADET …

Ponatinib

Ponatinib is a novel Bcr-Abl tyrosine kinase inhibitor that is especially effective against the T315I mutation for the treatment of chronic myeloid leukemia. FDA approved on December 14, 2012.
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … ICLUSIG FILM-COATED TABLET 45 MG ... ICLUSIG FILM-COATED TABLET 15 MG ... ICLUSIG 15 MG FILM-COATED TABLETS …

Ibrutinib

Ibrutinib is a small molecule that acts as an irreversible potent inhibitor of Burton's tyrosine kinase. It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies in clinical trials. Ibrutinib was developed by Pharmacyclics Inc and was first approved by the FDA in...
Approved
Matched Description: … It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies ... [A32299] Ibrutinib was developed by Pharmacyclics Inc and was first approved by the FDA in November 2013 ... [L45894] Ibrutinib was approved by the EMA in October 2014 [L45884] and by Health Canada in November …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … IMBRUVICA FILM-COATED TABLETS 140MG ... IMBRUVICA FILM-COATED TABLETS 560MG ... IMBRUVICA FILM-COATED TABLETS 420MG …

Methimazole

Methimazole is a thionamide antithyroid agent that inhibits the synthesis of thyroid hormones.[A184559,A184733,A184694] It was first introduced as an antithyroid agent in 1949 and is now commonly used in the management of hyperthyroidism, particularly in those for whom more aggressive options such as surgery or radioactive iodine therapy are inappropriate.[L8336,L8339]...
Approved
Matched Description: … [A184559,A184733,A184694] It was first introduced as an antithyroid agent in 1949[A184502] and is now ... potent than the other major antithyroid thionamide used in North America, [propylthiouracil],[L8339] and ... metabolite of the pro-drug [carbimazole], which is an antithyroid medication used in the United Kingdom and …
Matched Categories: … Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Mar-methimazole ... PERİZOL 20 MG FİLM TABLET, 100 ADET ... PERİZOL 20 MG FİLM TABLET, 30 ADET …

Letrozole

Letrozole, or CGS 20267, is an oral non-steroidal type II aromatase inhibitor first described in the literature in 1990.[A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like exemestane and anastrozole, meaning it does not significantly affect cortisol, aldosterone, and thyroxine. Letrozole was granted FDA approval on 25 July 1997.
Approved
Investigational
Matched Description: … ], meaning it does not significantly affect cortisol, aldosterone, and thyroxine. ... [A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like [exemestane] and [anastrozole …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Mar-letrozole ... Letara Film Coated Tablet 2.5mg ... Trozet Film Coated Tablet 2.5mg …

Bisoprolol

Bisoprolol is a cardioselective β1-adrenergic blocking agent used to treat high blood pressure.[A180472,L7219] It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs. Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor...
Approved
Matched Description: … A180472] Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor selectivity and ... alternative to non-selective β-blocker drugs in the treatment of hypertension such as [Carvedilol] and ... It may be used alone or in combination with other drugs to manage hypertension[L7219] and can be useful …
Matched Mixtures name: … KARDORITM PLUS 10 MG/25 MG FILM TABLET ,FILM TABLET, 30 ADET ... Cosyrel 5mg/5mg film-coated tablets ... COSYREL FILM-COATED TABLET 5 mg/ 5 mg …
Matched Categories: … Beta Blocking Agents and Thiazides ... ramipril and bisoprolol ... bisoprolol and thiazides ... Beta blocking agents and calcium channel blockers ... perindopril and bisoprolol …
Matched Products: … Concor 5mg Film coated Tablet ... Concor 10mg Film coated Tablet ... BISOPRO FILM-COATED TABLET 2.5MG …

Fesoterodine

Fesoterodine is an antimuscarinic prodrug for the treatment of overactive bladder syndrome.
Approved
Matched Categories: … Drugs for Urinary Frequency and Incontinence ... Genito Urinary System and Sex Hormones …
Matched Products: … FOSETAZ 4 MG UZATILMIŞ SALIMLI FİLM KAPLI TABLET, 14 ADET ... FOSETAZ 4 MG UZATILMIŞ SALIMLI FİLM KAPLI TABLET, 28 ADET ... FOSETAZ 4 MG UZATILMIŞ SALIMLI FİLM KAPLI TABLET, 84 ADET …
Displaying drugs 901 - 925 of 1133 in total