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Displaying drugs 901 - 925 of 1075 in total
Abrocitinib is an oral small-molecule inhibitor of Janus kinase 1 (JAK1). Janus kinases are intracellular enzymes involved in transduction pathways that regulate hematopoiesis and immune cell function. The Janus kinase (JAK)–signal transducer and activator of transcription (STAT) signalling pathway plays a central role in the pathogenesis of a variety of...
Approved
Investigational
Matched Description: … Janus kinases are intracellular enzymes involved in transduction pathways that regulate hematopoiesis and ... [L39774] The Janus kinase (JAK)–signal transducer and activator of transcription (STAT) signalling pathway ... plays a central role in the pathogenesis of a variety of autoimmune and inflammatory diseases, including …
Matched Products: … CİBİNQO 50 MG FİLM KAPLI TABLET, 28 ADET ... CİBİNQO 200 MG FİLM KAPLI TABLET, 28 ADET ... CİBİNQO 100 MG FİLM KAPLI TABLET, 28 ADET …
A broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.
Approved
Investigational
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Matched Products: … REKSOTİN 200 MG FİLM TABLET, 6 TABLET ... REKSOTİN 400 MG FİLM TABLET, 14 TABLET …
Luseogliflozin has been used in trials studying the treatment of Diabetes Melltius, Type 2.
Investigational
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Lusefi 5mg film-coated tablet ... Lusefi 2.5mg film-coated tablet …
Chronic venous insufficiency is a common condition the western population. Compression and pharmacotherapy are frequently used to manage chronic venous insufficiency, improving circulation and symptoms of venous disease. Diosmin is a bioflavonoid isolated from various plants or synthesized from hesperidin. It is used for the improvement of capillary fragility or...
Approved
Investigational
Matched Description: … circulation and symptoms of venous disease. ... Compression and pharmacotherapy are frequently used to manage chronic venous insufficiency, improving ... Diosmin is widely available over-the-counter and demonstrates a favourable a favorable safety profile …
Matched Mixtures name: … VENAFIX (Diosmin and Hesperidin Tablet) ... Davmorid Film Coated Tablet ... DIOSPER FILM COATED TABLET …
Matched Products: … DAFLON FILM-COATED TABLET 1000 mg ... RUVENTIN FILM COATED TABLET 500MG ... DAFLON 500 MG FILM TABLET, 60 ADET …
Vemurafenib is a competitive kinase inhibitor with activity against BRAF kinase with mutations like V600E. It exerts its function by binding to the ATP-binding domain of the mutant BRAF. Vemurafenib was co-developed by Roche and Plexxikon and it obtained its FDA approval on August 17, 2011, under the company Hoffmann...
Approved
Matched Description: … [A31270] Vemurafenib was co-developed by Roche and Plexxikon and it obtained its FDA approval on August …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … ZELBORAF 240 MG FILM KAPLI TABLET ,56 FILM KAPLI TABLET ... Zelboraf 240mg film-coated tablets …
Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)1B/1D/(1F) receptor agonists used to treat acute migraine.[A462, L12978] Sumatriptan was the first triptan to be developed, but had poor oral bioavailability and lipophilicity. This led to the development of second-generation triptans, including almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, and zolmitriptan. Triptans...
Approved
Investigational
Matched Description: … [A193797] Zolmitriptan was first approved by the FDA for sale by Zeneca Pharmaceuticals under the ... It is currently available in both tablet and nasal spray forms.[L12978] ... A462, L12978] [Sumatriptan] was the first triptan to be developed, but had poor oral bioavailability and
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Products: … MIGTERA 5 MG FİLM TABLET, 2 ADET ... MIGTERA 5 MG FİLM TABLET, 3 ADET ... MIGTERA 5 MG FİLM TABLET, 6 ADET …
Vardenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) and an oral therapy for the treatment of erectile dysfunction.[L45563,L45568] During sexual stimulation, nitric oxide (NO) is released from nerve endings and endothelial cells in the corpus cavernosum, activating the enzyme guanylate cyclase and increasing the...
Approved
Matched Description: … PDE5 inhibitors, such as vardenafil, inhibit the degradation of cGMP and allow increased blood flow into ... selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) and ... [L45563,L45568] During sexual stimulation, nitric oxide (NO) is released from nerve endings and endothelial …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … VAREKSİL 5 MG FİLM KAPLI TABLET, 4 ADET ... VAREKSİL 10 MG FİLM KAPLI TABLET, 4 ADET ... VAREKSİL 20 MG FİLM KAPLI TABLET, 2 ADET …
Tolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.
Approved
Investigational
Matched Description: … Tolterodine acts on M2 and M3 subtypes of muscarinic receptors. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Matched Products: … TOLTEX 2 MG FILM TABLET, 28 ADET ... TOLTEX FİLM 1 MG TABLET , 28 ADET ... URIDYN 1 MG FILM TABLET ,28 ADET …
Sodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine. It usually results in a bowel movement after 30 minutes to 6 hours.
Approved
Matched Synonyms: … Phosphoric acid, monosodium salt, anhydrous …
Matched Description: … Sodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine …
Matched Mixtures name: … Phospho-soda Buffered Saline Laxative ... Solution Saline Sterile Aux Phosphates ... Ionosol and Dextrose …
Matched Categories: … Potassium Salt ... Phosphate salts ... Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Asciminib is a tyrosine kinase inhibitor (TKI) used in the treatment of chronic-phase Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML). More specifically, it is an inhibitor of the ABL1 kinase activity of the BCR-ABL1 fusion protein which serves as a driver of CML proliferation in most patients with the disease....
Approved
Investigational
Matched Description: … those that target the active conformation of the kinase domain ([dasatinib], [bosutinib]) and those ... Existing inhibitors of ABL compete at the ATP binding sites of these proteins and can be classified into ... in that it acts as an allosteric inhibitor, binding at the myristoyl pocket of the BCR-ABL1 protein and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … AZEVAY 20 MG FİLM KAPLI TABLET , 60 ADET ... AZEVAY 40 MG FİLM KAPLI TABLET , 60 ADET …
Finasteride is a synthetic 4-azasteroid compound and specific inhibitor of steroid Type II 5α-reductase, which is an intracellular enzyme that converts the androgen testosterone into 5α-dihydrotestosterone (DHT). It works in a similar fashion as dutasteride, which is another 5-alpha-reductase inhibitor, by exerting antiandrogenic effects. Finasteride is an orally active drug...
Approved
Matched Description: … Finasteride is a synthetic 4-azasteroid compound [L10565] and specific inhibitor of steroid Type II 5α-reductase ... first approved by the FDA in 1992 for the treatment of benign prostatic hyperplasia to improve symptoms and ... [L6244] Finasteride is commonly marketed under the brand names Propecia and Proscar to be used aloneo …
Matched Categories: … doxazosin and finasteride ... alfuzosin and finasteride ... finasteride and tadalafil ... Skin and Mucous Membrane Agents ... Genito Urinary System and Sex Hormones …
Matched Products: … FINASTERID - CT 5MG FILM ... FINASTERID ARISTO 5MG FILM ... FINARID 5 MG FİLM TABLET, 30 ADET …
Bisoprolol is a cardioselective β1-adrenergic blocking agent used to treat high blood pressure.[A180472,L7219] It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs. Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor...
Approved
Matched Description: … A180472] Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor selectivity and ... alternative to non-selective β-blocker drugs in the treatment of hypertension such as [Carvedilol] and ... It may be used alone or in combination with other drugs to manage hypertension[L7219] and can be useful …
Matched Mixtures name: … KARDORITM PLUS 10 MG/25 MG FILM TABLET ,FILM TABLET, 30 ADET ... Cosyrel 5mg/5mg film-coated tablets ... Cosyrel 5mg/10mg film-coated tablets …
Matched Categories: … Beta Blocking Agents and Thiazides ... ramipril and bisoprolol ... bisoprolol and thiazides ... perindopril and bisoprolol ... bisoprolol and amlodipine …
Matched Products: … Concor 5mg Film coated Tablet ... ADROTEN FILM-COATED TABLET 5MG ... Concor 10mg Film coated Tablet …
Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. Vilazodone may also be associated with less sexual dysfunction and weight gain . Vilazodone was given FDA approval on January 21, 2011[L6046,A177622].
Approved
Matched Description: … (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. ... Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine ... Vilazodone may also be associated with less sexual dysfunction and weight gain[A6947]. …
Matched Categories: … Serotonin antagonist and reuptake inhibitors (SARIs) …
Matched Products: … ZİLADONE 10 MG FİLM KAPLI TABLET, 30 ADET ... ZİLADONE 20 MG FİLM KAPLI TABLET, 30 ADET ... ZİLADONE 40 MG FİLM KAPLI TABLET, 30 ADET …
Piracetam is a nootropic drug in the racetams group, with chemical name 2-oxo-1-pyrrolidine acetamide. It shares the same 2-oxo-pyrrolidone base structure with pyroglutamic acid and is a cyclic derivative of the neurotransmitter γ-aminobutyric acid (GABA). However its mechanism of action differ from that of endogenous GABA. Piracetam has neuroprotective and...
Approved
Investigational
Matched Description: … Piracetam has neuroprotective and anticonvulsant properties and is reported to improve neural plasticity ... It shares the same 2-oxo-pyrrolidone base structure with pyroglutamic acid and is a cyclic derivative ... Its efficacy is documented in cognitive disorders and dementia, vertigo, cortical myoclonus, dyslexia …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … KNOWFUL FILM COATED TABLET 800MG ... Ceretam 800mg Film-Coated Tablet ... KNOFUL (FILM COATED TABLET 800 MG) …
Drospirenone is a synthetic progestin commonly found in the popular oral contraceptive, Yaz in combination with Ethinyl estradiol. Most recently, it was approved by both Health Canada and the FDA in combination with Estetrol as an oral contraceptive therapy.[L33199,L33174] Aside from its contraceptive effects, drospirenone is used with estrogens to...
Approved
Matched Description: … [L7973] Most recently, it was approved by both Health Canada and the FDA in combination with [Estetrol ... ,L33174] Aside from its contraceptive effects, drospirenone is used with estrogens to control acne and ... during the postpartum period, and this should be considered when assessing potential risks of hormonal …
Matched Mixtures name: … Drospirenone and Ethinyl Estradiol ... Drospirenone and Ethinyl Estradiol ... Drospirenone and Ethinyl Estradiol …
Matched Categories: … Combination Contraceptives (with Estrogen and derivatives) ... drospirenone and estetrol ... drospirenone and estrogen ... Genito Urinary System and Sex Hormones ... drospirenone and ethinylestradiol …
Matched Products: … SLINDA FILM-COATED TABLETS 4MG ... ZLYNDA 4 MG FİLM KAPLI TABLET, 28 ADET ... ZLYNDA 4 MG FİLM KAPLI TABLET, 84 ADET …
Eletriptan is a second generation triptan drug developed by Pfizer Inc for the treatment of migraine headaches.
Approved
Investigational
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Products: … RELPAX 40 MG FILM TABLET, 2 ADET ... RELPAX 40 MG FILM TABLET, 4 ADET ... RELPAX 40 MG FILM TABLET, 1 ADET …
Frovatriptan is a triptan drug developed by Vernalis for the treatment of migraine headaches, in particular those associated with menstruation. Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head.
Approved
Investigational
Matched Description: … Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head. …
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Products: … MIGREX 2.5 MG FILM TABLET, 12 ADET ... MIGREX 2.5 MG FILM TABLET, 3 ADET ... MIGREX 2.5 MG FILM TABLET, 6 ADET …
Experimental
Matched Name: … 5-Pyrimidinyl)Methyl]-4-Methyl-5-(4,6,6-Trihydroxy-3,5-Dioxa-4,6-Diphosphahex-1-Yl)Thiazolium Inner Salt
Ivabradine is a novel heart rate lowering medicine for the symptomatic management of stable angina pectoralis and symptomatic chronic heart failure. Ivabradine, brand name Corlanor, was approved by the FDA in April 2015 for the treatment of chronic heart failure in patients with an ejection fraction of ≤35%, in sinus...
Approved
Matched Description: … is a novel heart rate lowering medicine for the symptomatic management of stable angina pectoralis and ... Although non-dihydropyridine calcium channel blockers and beta blockers also effectively lower heart ... pacemaker current (If) in the sinoatrial node in a dose-dependent fashion, resulting in a lower heart rate and
Matched Mixtures name: … IMPLICOR 50MG/5MG FILM-COATED TABLETS ... IMPLICOR 25MG/5MG FILM-COATED TABLETS ... IMPLICOR 25MG/7.5MG FILM-COATED TABLETS …
Matched Categories: … metoprolol and ivabradine ... carvedilol and ivabradine …
Matched Products: … CORALAN 5MG FILM-COATED TABLETS ... CORALAN 7.5MG FILM-COATED TABLETS ... IVASWIFT FILM-COATED TABLET 5MG …
Raloxifene is a second generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation.[A4979,T28] Exhibiting tissue-specific effects distinct from estradiol, raloxifene is the first of the benzothiophene group of antiestrogens to be labelled a SERM....
Approved
Investigational
Matched Description: … in postmenopausal women with osteoporosis or those who are at high risk for invasive breast cancer. ... uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation. ... generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and
Matched Categories: … Genito Urinary System and Sex Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Modulators of the Genital System …
Matched Products: … ELASTA 60mg FILM-COATED TABLETS ... Raloxon Film-coated Tablets 60 mg ... ROXIMAX 60 MG FİLM TABLET, 28 ADET …
Udenafil is a new phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction (ED). It has been approved in South Korea and will be marketed under the brand name Zydena. It is not yet approved for use in the U.S., E.U., or Canada.
Approved
Investigational
Matched Description: … It has been approved in South Korea and will be marketed under the brand name Zydena. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … ZYDENA 100 MG FILM TABLET, 2 ADET ... ZYDENA 100 MG FILM TABLET, 4 ADET …
Valganciclovir hydrochloride (Valcyte, manufactured by Roche) is an antiviral medication used to treat cytomegalovirus infections. As the L-valyl ester of ganciclovir, it is actually a prodrug for ganciclovir. After oral administration, it is rapidly converted to ganciclovir by intestinal and hepatic esterases.
Approved
Investigational
Matched Description: … After oral administration, it is rapidly converted to ganciclovir by intestinal and hepatic esterases …
Matched Categories: … Ganciclovir and prodrug ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … CITOVIR 450 MG FILM TABLET, 60 ADET ... VALCYTE 450 MG FILM TABLET, 60 ADET ... AVALCEPT 450 MG FILM KAPLI TABLET, 60 ADET …
Lapatinib is an anti-cancer drug developed by GlaxoSmithKline (GSK) as a treatment for solid tumours such as breast and lung cancer. It was approved by the FDA on March 13, 2007, for use in patients with advanced metastatic breast cancer in conjunction with the chemotherapy drug capecitabine. Lapatinib is a...
Approved
Investigational
Matched Description: … anti-cancer drug developed by GlaxoSmithKline (GSK) as a treatment for solid tumours such as breast and ... Lapatinib is a human epidermal growth factor receptor type 2 (HER2/ERBB2) and epidermal growth factor …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … TYKERB 250 MG FILM TABLET, 70 ADET ... TYKERB FILM-COATED TABLETS 250MG …
A reversible monoamine oxidase inhibitor (MAOI) selective for isoform A (RIMA) used to treat major depressive disorder. Most meta-analyses and most studies indicate that in the acute management of depression, moclobemide is more efficacious than placebo medication and similarly efficacious as tricyclic antidepressants (TCA) or selective serotonin reuptake inhibitors (SSRIs)....
Approved
Investigational
Matched Description: … Most meta-analyses and most studies indicate that in the acute management of depression, moclobemide ... is more efficacious than placebo medication and similarly efficacious as tricyclic antidepressants (TCA ... Due to negligible anticholinergic and antihistaminic actions, moclobemide has been better tolerated than …
Matched Categories: … Benzamides and benzamide derivatives …
Matched Products: … Aurorix Film Coated Tablet 150mg ... Aurorix Film Coated Tablet 300mg ... AURORIX 150 MG FILM KAPLI TABLET, 30 ADET …
A tetracyclic compound with antidepressant effects. Mianserin was previously available internationally, however in most markets it has been phased out in favour of mirtazapine.
Approved
Investigational
Matched Products: … MIANSERIN-REMEDICA 30mg Film-Coated Tablets ... MIANSERIN-REMEDICA 10mg Film-Coated Tablets ... TOLVON 30 MG FİLM KAPLI TABLET, 14 ADET …
Displaying drugs 901 - 925 of 1075 in total