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Displaying drugs 76 - 100 of 14862 in total

Dopamine

One of the catecholamine neurotransmitters in the brain. It is derived from tyrosine and is the precursor to norepinephrine and epinephrine. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (receptors, dopamine) mediate its action.
Approved
Matched Description: … It is derived from tyrosine and is the precursor to norepinephrine and epinephrine. ... Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating …
Matched Mixtures name: … Dopamine Hydrochloride and 5% Dextrose Injection USP ... Dopamine Hydrochloride and 5% Dextrose Injection USP ... Dopamine Hydrochloride and 5% Dextrose Injection USP …
Matched Categories: … Adrenergic and Dopaminergic Agents …
Matched Products: … DOPamine Hydrochloride and Dextrose ... Dopamine Hydrochloride and Dextrose ... DOPamine HYDROCHLORIDE AND DEXTROSE …

Potassium carbonate

Potassium carbonate (K2CO3) is a white salt, soluble in water (insoluble in ethanol) which forms a strongly alkaline solution. It can be made as the product of potassium hydroxide's absorbent reaction with carbon dioxide. It presents a large capacity to absorb moisture.
Approved
Matched Mixtures name: … Vit C W Calc-mag and Potass Powder ... Buffered Vitamin C Powder With Ca Mg and K …
Matched Products: … Moonstar Face and Body Mist …

Eugenol

Eugenol is a naturally occurring phenolic molecule found in several plants such as cinnamon, clove, and bay leaves. It has been used as a topical antiseptic as a counter-irritant and in dental preparations with zinc oxide for root canal sealing and pain control. Although not currently available in any FDA-approved...
Approved
Matched Description: … for root canal sealing and pain control. ... Eugenol is a naturally occurring phenolic molecule found in several plants such as cinnamon, clove, and ... It has been used as a topical antiseptic as a counter-irritant and in dental preparations with zinc oxide …
Matched Products: … Walgreens Natural Eugenol/Toothache Medication with cotton pellets and tweezers …

Ofatumumab

Ofatumumab is a novel anti-CD20 monoclonal antibody that targets B-cells. It is an IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic mouse and hybridoma technology. Ofatumumab works by recognizing antigens that are expressed on the tumour cells in certain cancers; however, the antigen is...
Approved
Matched Description: … Ofatumumab is a novel anti-CD20 monoclonal antibody that targets B-cells. ... It is an IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic ... L12612] Although it has a similar molecular mechanism of action as [rituximab], another CD-20 monoclonal antibody …
Matched Categories: … Monoclonal antibodies and antibody drug conjugates ... Amino Acids, Peptides, and Proteins ... CD20-directed Cytolytic Antibody ... CD20-directed Antibody Interactions ... Antineoplastic and Immunomodulating Agents …

Isatuximab

Isatuximab (formerly SAR650984) is a humanized, IgG1-derived monoclonal antibody (mAb) produced from a Chinese hamster ovary (CHO) cell line.[L12099,A191799] Structurally, isatuximab is comprised of two identical immunoglobulin kappa light chains and two identical immunoglobulin gamma heavy chains. It is a cytolytic antibody targeted against CD38, a glycoprotein found on the...
Approved
Investigational
Matched Description: … L12099,A191799] Structurally, isatuximab is comprised of two identical immunoglobulin kappa light chains and ... research,[A38676,A191826,A191829] isatuximab was granted Orphan Drug designation and approved on March ... Isatuximab (formerly SAR650984) is a humanized, IgG1-derived monoclonal antibody (mAb) produced from …
Matched Categories: … Monoclonal antibodies and antibody drug conjugates ... Amino Acids, Peptides, and Proteins ... CD38-directed Cytolytic Antibody ... CD38-directed Antibody Interactions ... Antineoplastic and Immunomodulating Agents …

Arsenic trioxide

Arsenic trioxide is a chemotherapeutic agent of idiopathic function used to treat leukemia that is unresponsive to first line agents. It is suspected that arsenic trisulfide induces cancer cells to undergo apoptosis. In general, arsenic is known to be a naturally toxic substance capable of eliciting a variety of dangerous...
Approved
Investigational
Matched Description: … It is suspected that arsenic trisulfide induces cancer cells to undergo apoptosis. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Triptorelin

Triptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion. After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis. Serum testosterone concentrations may fall to levels...
Approved
Vet approved
Matched Description: … and testicular and ovarian steroidogenesis. ... After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production …
Matched Categories: … Hormones and Related Agents ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION 3.75 mg/vial ... POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION 11.25 mg/vial …

Tremelimumab

Tremelimumab, formerly known as ticilimumab, is a fully human IgG2 monoclonal antibody directed against cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4). CTLA-4 is a cell surface receptor expressed on activated T cells to act as a negative regulator for T cells. By binding to CTLA-4, tremelimumab enhances T cell-mediated killing of tumours...
Approved
Investigational
Matched Description: … Tremelimumab, formerly known as ticilimumab, is a fully human IgG2 monoclonal antibody directed against ... [A253717] By binding to CTLA-4, tremelimumab enhances T cell-mediated killing of tumours and reduces ... investigated in other cancers, such as colon cancer, pancreatic cancer, non-small cell lung cancer (NSCLC), and …
Matched Categories: … Monoclonal antibodies and antibody drug conjugates ... CTLA-4-directed Blocking Antibody ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …

Carboxymethylcellulose

Carboxymethylcellulose is a cellulose derivative that consists of the cellulose backbone made up of glucopyranose monomers and their hydroxyl groups bound to carboxymethyl groups. It is added in food products as a viscosity modifier or thickener and emulsifier. It is also one of the most common viscous polymers used in...
Approved
Investigational
Matched Description: … It is added in food products as a viscosity modifier or thickener and emulsifier. ... is a cellulose derivative that consists of the cellulose backbone made up of glucopyranose monomers and ... in the treatment of aqueous tear-deficient dry eye symptoms and ocular surface staining [A33029]. …
Matched Mixtures name: … Equate Day and Night Restore Tears ... Refresh Trial Pack (refresh Tears, Refresh Liquigel and Refresh Ultra) ... Refresh Trial Pack (refresh Tears, Refresh Liquigel and Refresh Ultra) …
Matched Categories: … Anorexigenic Agents & Respiratory and CNS Stimulants …
Matched Products: … Up and Up Lubricant ... Up and Up Lubricant Refreshing ... Up and Up Lubricant Refreshing Tears …

Obinutuzumab

Obinutuzumab is a humanized monoclonal antibody used as a combination treatment with chlorambucil to treat patients with untreated chronic lymphocytic leukemia. It was approved by the FDA in November 2013 and is marketed under the brand name Gazyva. There is a black box warning of fatal Hepatitis B Virus (HBV)...
Approved
Investigational
Matched Description: … Obinutuzumab is a humanized monoclonal antibody used as a combination treatment with chlorambucil to ... It was approved by the FDA in November 2013 and is marketed under the brand name Gazyva. ... There is a black box warning of fatal Hepatitis B Virus (HBV) reactivation and fatal Progressive Multifocal …
Matched Categories: … Monoclonal antibodies and antibody drug conjugates ... Amino Acids, Peptides, and Proteins ... CD20-directed Cytolytic Antibody ... CD20-directed Antibody Interactions ... Antineoplastic and Immunomodulating Agents …

Brolucizumab

Brolucizumab, also known as RTH258 or ESBA1008, is a monoclonal antibody indicated to treat neovascular age related macular degeneration. Brolucizumab was granted FDA approval in October 2019.
Approved
Investigational
Matched Description: … Brolucizumab, also known as RTH258 or ESBA1008,[A187211] is a monoclonal antibody indicated to treat …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Raxibacumab

Raxibacumab is a human IgG1λ monoclonal antibody that binds the protective antigen (PA) component of B. anthracis toxin. Raxibacumab has a molecular weight of approximately 146 kilodaltons. Raxibacumab is produced by recombinant DNA technology in a murine cell expression system. FDA approved on December 14, 2012.
Approved
Matched Description: … Raxibacumab is a human IgG1λ monoclonal antibody that binds the protective antigen (PA) component of …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins ... Anthrax Protective Antigen-directed Antibody ... Anthrax Protective Antigen-directed Antibody Interactions …

Ocrelizumab

Ocrelizumab is a CD20-directed cytolytic antibody indicated for the treatment of patients with primary progressive or relapsing forms of multiple sclerosis (MS). It is a second-generation recombinant humanized monoclonal IgG1 antibody that selectively targets B-cells that express the CD20 antigen. Compared to non-humanized CD20 antibodies such as rituximab, ocrelizumab is...
Approved
Investigational
Matched Description: … Ocrelizumab is a CD20-directed cytolytic antibody indicated for the treatment of patients with primary ... [L42895] It is a second-generation recombinant humanized monoclonal IgG1 antibody that selectively targets ... inflammatory, autoimmune disease of the central nervous system that leads to neurological disabilities and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... CD20-directed Cytolytic Antibody ... CD20-directed Antibody Interactions ... Antineoplastic and Immunomodulating Agents …

Lanolin

Lanolin is a yellow fat obtained from sheep's wool. It is used as an emollient, cosmetic, and pharmaceutic aid . The US federal code of regulations states that lanolin in the concentration range of 12-50% may be included in over the counter skin ointments . Lanolin is the purified, secreted...
Approved
Matched Description: … It is used as an emollient, cosmetic, and pharmaceutic aid [L2580]. ... Lanolin is used in the protection, treatment, and cosmetic enhancement of human skin. ... as an active ingredient in over the counter topical products such as ointments, lubricants, lotions and …
Matched Mixtures name: … A and D Diaper Rash and Skin Protectant ... Vitamin A and D ... Vitamins A and D …
Matched Categories: … Basic Ointments and Protectants …
Matched Products: … Soothe and Cool Free Medseptic Skin Protectant …

Water

Water (chemical formula: H2O) is a transparent fluid which forms the world's streams, lakes, oceans and rain, and is the major constituent of the fluids of organisms. As a chemical compound, a water molecule contains one oxygen and two hydrogen atoms that are connected by covalent bonds. Water is a...
Approved
Matched Description: … rain, and is the major constituent of the fluids of organisms. ... its solid state, ice; and gaseous state, steam (water vapor). ... Water (chemical formula: H2O) is a transparent fluid which forms the world's streams, lakes, oceans and …
Matched Mixtures name: … Medium Cuts and Scratches ... Good Neighbor Pharmacy Emergency Preparedness and First Aid Contains 167 Pieces ... SOLNARA Everything Blood circulation Nattokinase(Control blood pressure and Improve blood circulation …
Matched Products: … Salinaax Eye Wash and Skin Flush ... Aerowash Eyewash and Skin-Rinse ... Xpect First aid Buffered Eye and Skin …

Ipilimumab

Ipilimumab is a fully humanized IgG1 monoclonal antibody that blocks cytotoxic T lymphocyte antigen-4 (CTLA-4). Blocking CTLA-4 removes an inhibitory signal from reducing the activity of T lymphocytes.[A35065,A35080,L12126] Ipilimumab was developed by Bristol-Myers Squibb and Medarex. Ipilimumab was granted FDA approval on 25 March 2011.
Approved
Matched Description: … [A35065,A35080,L12126] Ipilimumab was developed by Bristol-Myers Squibb and Medarex. ... Ipilimumab is a fully humanized IgG1 monoclonal antibody that blocks cytotoxic T lymphocyte antigen-4 …
Matched Categories: … Monoclonal antibodies and antibody drug conjugates ... Amino Acids, Peptides, and Proteins ... CTLA-4-directed Blocking Antibody ... CTLA-4-directed Antibody Interactions ... Antineoplastic and Immunomodulating Agents …

Loratadine

Loratadine is a second generation antihistamine used to manage symptoms of allergic rhinitis. A lack of sedative and CNS adverse effects make loratadine, along with other second generation antihistamines, preferable over their 1st generation counterparts in many clinical situations.
Approved
Investigational
Matched Description: … [A176435] A lack of sedative and CNS adverse effects make loratadine, along with other second generation …
Matched Mixtures name: … Up and Up allergy and congestion relief ... Loratadine and Pseudoephedrine ... Smart Sense allergy and congestion relief indoor and outdoor allergies …
Matched Categories: … Loratadine and derivatives …
Matched Products: … Up and Up Allergy Relief ... Up and Up Childrens Allergy ... Berkley and Jensen Allergy Relief …

Basiliximab

A recombinant chimeric (murine/human) monoclonal antibody (IgG1k) that functions as an immunosuppressive agent, specifically binding to and blocking the interleukin-2 receptor a-chain (IL-2R alpha, also known as CD25 antigen) on the surface of activated T-lymphocytes. It is a 144 kDa glycoprotein obtained from fermentation of an established mouse myeloma cell...
Approved
Investigational
Matched Description: … RFT5 antibody that binds selectively to the IL-2R alpha. ... A recombinant chimeric (murine/human) monoclonal antibody (IgG1k) that functions as an immunosuppressive ... light chain constant region genes and mouse heavy and light chain variable region genes encoding the …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Interleukin-2 Receptor Blocking Antibody ... Interleukin 2 Receptor-directed Antibody Interactions …

Rituximab

Rituximab is a genetically engineered chimeric murine/human monoclonal antibody directed against the CD20 antigen found on the surface of normal and malignant B lymphocytes. The antibody is an IgG1 kappa immunoglobulin containing murine light and heavy-chain variable region sequences and human constant region sequences , [FDA label]. It was originally...
Approved
Matched Description: … The antibody is an IgG1 kappa immunoglobulin containing murine light and heavy-chain variable region ... Rituximab is a genetically engineered chimeric murine/human monoclonal antibody directed against the ... sequences and human constant region sequences [A40017], [FDA label]. …
Matched Categories: … Monoclonal antibodies and antibody drug conjugates ... Amino Acids, Peptides, and Proteins ... CD20-directed Cytolytic Antibody ... CD20-directed Antibody Interactions …

Toripalimab

The proliferation of some cancers can be attributed, at least in part, to the suppression of host tumor surveillance. One mechanism by which this occurs is through the overexpression of programmed cell death ligand (PD-L1) - the binding of PD-L1 (and PD-L2) to its target receptor (PD-1) results in the...
Approved
Investigational
Matched Description: … [L48681] Toripalimab is a selective, recombinant, humanized IgG4 monoclonal antibody targeted against ... production, and thus its overexpression can inhibit T-cell-mediated immune surveillance of tumors. ... through the overexpression of programmed cell death ligand (PD-L1)[A261506] - the binding of PD-L1 (and …
Matched Categories: … Monoclonal antibodies and antibody drug conjugates ... Programmed Death Receptor-1 Blocking Antibody ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …

Diphenhydramine

Diphenhydramine - perhaps known most commonly as its brand name formulation Benadryl - is a first-generation H1 receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and stings, and rashes [L5263, L5266, L5269, F3379]. However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269,...
Approved
Investigational
Matched Description: … stings, and rashes [L5263, L5266, L5269, F3379]. ... However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269, F3352]. ... receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and …
Matched Mixtures name: … Up and Up Nighttime Flu and Severe Cold and Cough ... Up and Up Flu and Severe Cold and Cough Relief ... Flu and Severe Cold and Cough …
Matched Categories: … Hypnotics and Sedatives ... naproxen and diphenhydramine ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Up and Up Allergy Relief ... Berkley and Jensen Allergy ... Up and Up Nighttime Sleep-aid …

Pembrolizumab

Pembrolizumab is a highly selective IgG4-kappa humanized monoclonal antibody against PD-1 receptors. It was generated by grafting the variable sequences of a very high-affinity mouse antihuman PD-1 antibody onto a human IgG4-kappa isotype containing a stabilizing S228P Fc mutation. It contains 32 cysteine residues and the complete folded molecule includes...
Approved
Matched Description: … as interchain bonds and 23 interchain bonds. ... Pembrolizumab is a highly selective IgG4-kappa humanized monoclonal antibody against PD-1 receptors. ... It was generated by grafting the variable sequences of a very high-affinity mouse antihuman PD-1 antibody …
Matched Categories: … Monoclonal antibodies and antibody drug conjugates ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Programmed Death Receptor-1 Blocking Antibody ... Programmed Death Receptor-1-directed Antibody Interactions …

Nivolumab

Nivolumab is a fully human IgG4 antibody targeting the immune checkpoint programmed death receptor-1 (PD-1). This antibody was produced entirely in mice and grafted onto human kappa and IgG4 Fc region with the mutation S228P for additional stability and reduced variability. It was developed by Bristol Myers Squibb. Nivolumab was...
Approved
Matched Description: … [L12129] This antibody was produced entirely in mice and grafted onto human kappa and IgG4 Fc region ... Nivolumab is a fully human IgG4 antibody targeting the immune checkpoint programmed death receptor-1 ... with the mutation _S228P_ for additional stability and reduced variability. …
Matched Categories: … Monoclonal antibodies and antibody drug conjugates ... Programmed Death Receptor-1 Blocking Antibody ... nivolumab and relatlimab ... Amino Acids, Peptides, and Proteins ... Programmed Death Receptor-1-directed Antibody Interactions …

Sodium bicarbonate

Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
Approved
Matched Description: … powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and …
Matched Mixtures name: … Top Value Effervescent Pain Relief ... Top Value Effervescent Pain Relief ... Up and Up Antacid and Pain Relief …
Matched Categories: … Antacids and Adsorbents ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Matched Products: … Arm and Hammer Baking Soda …

Alemtuzumab

Alemtuzumab is a humanized monoclonal antibody specific to lymphocyte antigens. It is a recombinant DNA-derived humanized monoclonal antibody (Campath-1H) that is directed against the 21-28 kD cell surface glycoprotein, CD52. The Campath-1H antibody is an IgG1 kappa with the human variable framework and constant regions, and complementarity-determining regions from a...
Approved
Investigational
Matched Description: … The Campath-1H antibody is an IgG1 kappa with the human variable framework and constant regions, and ... Alemtuzumab is a humanized monoclonal antibody specific to lymphocyte antigens. ... complementarity-determining regions from a murine (rat) monoclonal antibody (Campath-1G). …
Matched Categories: … Amino Acids, Peptides, and Proteins ... CD52-directed Cytolytic Antibody ... CD52-directed Antibody Interactions ... Antineoplastic and Immunomodulating Agents …
Displaying drugs 76 - 100 of 14862 in total