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Displaying drugs 976 - 1000 of 1064 in total

Imatinib

Imatinib is a small molecule kinase inhibitor that revolutionized the treatment of cancer, particularly chronic myeloid leukemia, in 2001. It was deemed a "miracle drug" due to its clinical success, as oncologist Dr. Brian noted that "complete hematologic responses were observed in 53 of 54 patients with CML treated with...
Approved
Matched Description: … responses were observed in 53 of 54 patients with CML treated with a daily dosage of 300 mg or more and ... [L42220] Imatinib was approved on February 1st ,2001 by the FDA and November 7th, 2001 by the EMA …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Benzamides and benzamide derivatives …
Matched Products: … IMATINIB BASICS 100MG ... IMATINIB BASICS 400MG …

PIKA rabies vaccine

PIKA rabies vaccine is a novel vaccine developed by YS Biopharma.
Investigational
Matched Synonyms: … PIKA adjuvant-based rabies vaccine …

Human papillomavirus type 18 L1 capsid protein residues 2-472 antigen

Approved
Investigational
Matched Name: … Human papillomavirus type 18 L1 capsid protein residues 2-472 antigen …

Ex vivo expanded autologous human corneal epithelial cells containing stem cells

Holoclar (ex vivo expanded autologous human corneal epithelial cells containing stem cells) is a stem cell therapy used to treat limbal stem cell deficiencies.
Investigational
Matched Name: … Ex vivo expanded autologous human corneal epithelial cells containing stem cells …
Matched Description: … Holoclar (_ex vivo_ expanded autologous human corneal epithelial cells containing stem cells) is a stem …

BRM-421

Investigational
Matched Synonyms: … Pigment Epithelium Derived Factor derived short peptide (Ac-Ser-Leu-Gly-Ala-Glu-Gln-Arg-Thr-Glu-Ser-Ile-Ile-His-Arg-Ala …

Magrolimab

Magrolimab is under investigation in clinical trial NCT02953782 (Trial of Magrolimab (Hu5f9-g4) in Combination With Cetuximab in Participants With Solid Tumors and Advanced Colorectal Cancer).
Investigational
Matched Synonyms: … Immunoglobulin g4(225-proline), anti-(human cd47 antigen) (human-mus musculus monoclonal hu5f9-g4 .gamma ... .4-chain), disulfide with human-mus musculus monoclonal hu5f9-g4 .kappa. …
Matched Description: … NCT02953782 (Trial of Magrolimab (Hu5f9-g4) in Combination With Cetuximab in Participants With Solid Tumors and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Iluzanebart

Investigational
Matched Synonyms: … on myeloid cells 2) (human monoclonal VGL101 γ1-chain), disulfide with human monoclonal VGL101 κ-chain ... Immunoglobulin G1 [296-cysteine,301-glycine,306-cysteine], anti-(human triggering receptor expressed …

Loncastuximab tesirine

Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients who have undergone prior systemic therapies with limited success. Prognosis is poor and more effective therapies are needed to treat relapsed/refractory cases and improve survival. On April 23 2021, the Food and Drug Administration granted accelerated...
Approved
Investigational
Matched Synonyms: … Humanized monoclonal immunoglobulin G1 antibody directed against human CD19 conjugated to SG3199 through …
Matched Description: … and improve survival. ... refractory B-cell lymphoma is based on promising results from the LOTIS-2 clinical trial. ... Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …

RP-A501

RP-A501 is a gene therapy product consisting of a recombinant adeno-associated virus serotype 9 (rAAV9) capsid containing the human LAMP2B transgene (AAV9:LAMP2B), which encodes lysosome-associated membrane protein 2 (LAMP-2). It is being investigated for Danon disease.
Investigational
Matched Synonyms: … Adeno-associated virus serotype 9 vector containing the human lysosome-associated membrane glycoprotein …
Matched Description: … product consisting of a recombinant adeno-associated virus serotype 9 (rAAV9) capsid containing the human …

Levocetirizine

Levocetirizine is a selective histamine H1 antagonist used to treat a variety of allergic symptoms.[A181748,A181790,L7694] It is the R enantiomer of cetirizine. Levocetirizine has greater affinity for the histamine H1 receptor than cetirizine. Levocetirizine was granted FDA approval in 1995.
Approved
Matched Categories: … Cetirizine and isomer …
Matched Products: … Basic Care Allergy Relief …

Sertraline

Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as Citalopram and Fluoxetine. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects. Several weeks of therapy with sertraline may be required before...
Approved
Matched Description: … is similar to drugs such as [Citalopram] and [Fluoxetine]. ... popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and ... classes of antidepressants, which frequently cause high levels of drowsiness, dizziness, blurred vision, and …
Matched Products: … SERTRALIN BASICS 50MG ... SERTRALIN BASICS 100MG …

Glenzocimab

Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human platetet glycoprotein vi) fab fragment (humanized monoclonal act017 .gamma …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Inolimomab

Inolimomab is under investigation as an agent to treat steroid-resistant graft vs host disease. It has thus far offered similar efficacy to other monoclonal antibody options, though it may carry a higher risk of infections.
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human interleukin 2 receptor alpha-chain) (mouse monoclonal B-B10 gammal-chain …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immunologic Factors …

Olanzapine

Olanzapine is a thienobenzodiazepine classified as an atypical or second-generation antipsychotic agent. The second-generation antipsychotics were introduced in the 90s and quickly gained traction due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility to drug-drug interactions. Olanzapine very closely resembles clozapine and only differs by...
Approved
Investigational
Matched Description: … and the absence of a chloride moiety. ... [A176996] The second-generation antipsychotics were introduced in the 90s and quickly gained traction ... due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility …
Matched Mixtures name: … Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine …
Matched Categories: … olanzapine and samidorphan ... Diazepines, Oxazepines, Thiazepines and Oxepines …
Matched Products: … OLANZAPIN BASICS 5MG ... OLANZAPIN BASICS 10MG ... OLANZAPIN BASICS 15MG …

Strimvelis

Investigational
Matched Synonyms: … enriched cell fraction that contains CD34+ cells transduced with retroviral vector that encodes for the human …

Ersodetug

Investigational
Matched Synonyms: … Immunoglobulin G2, anti-(human insulin receptor) (human monoclonal RZ358 γ2-chain), disulfide with human …

Efocipegtrutide

Efocipegtrutide is a long-acting, monomeric peptide triple agonist.
Investigational
Matched Synonyms: … GLUCAGON ANALOG CONJUGATED WITH HUMAN IMMUNOGLOBULIN G4 FRAGMENT ... IMMUNOGLOBULIN G4 (HUMAN .GAMMA.4-CHAIN C REGION C-TERMINAL FRAGMENT), DIMER, 1-(1-(3-HYDROXYPROPYL)- …

Clervonafusp alfa

Investigational
Matched Synonyms: … -glucosidase (human recombinant), disulfide with humanized monoclonal 3e10 .kappa.-chain ... cell-penetrating humanized fab fragment targeting the equilibrative nucleoside transporter 2 (ent2), fused with a human …

CYNK-101

CYNK-101 is an allogeneic human placental hematopoietic stem cell-derived natural killer (NK) cell therapy product that is genetically modified to express a variant of CD16 (CD16VP).
Investigational
Matched Synonyms: … allogeneic human placental hematopoietic stem cell derived natural killer (NK) cell therapy product that …
Matched Description: … CYNK-101 is an allogeneic human placental hematopoietic stem cell-derived natural killer (NK) cell therapy …

Tirabrutinib

Tirabrutinib is under investigation in clinical trial NCT02626026 (Safety and Pharmacokinetics of GS-4059 in Healthy Volunteers and Subjects With Rheumatoid Arthritis (RA)).
Investigational
Matched Synonyms: … ONO-4059 (free base) …
Matched Description: … 4059 in Healthy Volunteers and Subjects With Rheumatoid Arthritis (RA)). ... Tirabrutinib is under investigation in clinical trial NCT02626026 (Safety and Pharmacokinetics of GS- …

Lirentelimab

Lirentelimab is under investigation in clinical trial NCT04856891 (A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Duodenitis).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1, ANTI-(HUMAN SIALIC ACID-BINDINGE IG-LIKE LECTIN 8) (HUMAN-MUS MUSCULUS MONOCLONAL ... AK002 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL AK002 .KAPPA. …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Eptotermin alfa

A bone morphogenetic protein that is widely expressed during EMBRYONIC DEVELOPMENT. It is both a potent osteogenic factor and a specific regulator of nephrogenesis. Eptotermin alfa is an ingredient in the EMA-withdrawn product Osigraft.
Approved
Investigational
Withdrawn
Matched Synonyms: … Human recombinant bone morphogenetic protein 7 …
Matched Description: … It is both a potent osteogenic factor and a specific regulator of nephrogenesis. …
Matched Categories: … Biological Factors ... Amino Acids, Peptides, and Proteins ... Drugs Affecting Bone Structure and Mineralization ... Intercellular Signaling Peptides and Proteins …

Crovalimab

Crovalimab is under investigation in clinical trial NCT03157635 (Study to Assess Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Crovalimab in Healthy Volunteers and Participants With Paroxysmal Nocturnal Hemoglobinuria).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human complement c5)(humanized ro7112689 heavy chain), disulfide with humanized …
Matched Description: … under investigation in clinical trial NCT03157635 (Study to Assess Safety, Efficacy, Pharmacokinetics, and ... Pharmacodynamics of Crovalimab in Healthy Volunteers and Participants With Paroxysmal Nocturnal Hemoglobinuria …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Ocaratuzumab

Ocaratuzumab is a humanized monoclonal antibody directed against CD20. It is being investigated for cancers and autoimmune disorders.
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human B-lymphocyte antigen CD20 (B-lymphocyte surface antigen B1, Bp35, leukocyte …
Matched Description: … It is being investigated for cancers and autoimmune disorders. …
Matched Categories: … Amino Acids, Peptides, and Proteins …

D-3082-L

D-3082-L is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide (SLP) vaccine ISA101b.
Investigational
Matched Synonyms: … Human Papilloma Virus (HPV) Type 16 E6/e7 Synthetic Long Peptide (SLP) Vaccine Component D-3082-L …
Matched Description: … D-3082-L is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide …
Displaying drugs 976 - 1000 of 1064 in total