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Displaying drugs 10176 - 10200 of 12310 in total

AS-8112

AS-8112 is a synthetic compound that acts as a selective antagonist at the dopamine receptor subtypes D2 and D3, and the serotonin receptor 5-HT3. It has been shown to exert potent antiemetic effects in animal studies and has been investigated for potential medical use.
Experimental
Matched Iupac: … 5-bromo-N-[(6R)-1-ethyl-4-methyl-1,4-diazepan-6-yl]-2-methoxy-4-(methylamino)benzamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Mericitabine

Mericitabine has been investigated for the treatment of Hepatitis C, Chronic. Mericitabine is a polymerase inhibitor being developed for the treatment of chronic hepatitis C. Mericitabine is a prodrug of PSI-6130, which demonstrated excellent potency in preclinical studies. PSI-6130 is a pyrimidine nucleoside analog inhibitor of HCV RNA polymerase, an...
Investigational
Matched Iupac: … [(2R,3R,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4-fluoro-4-methyl-3-[(2-methylpropanoyl)oxy …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Entospletinib

Entospletinib has been used in trials studying the treatment of Oncology, Follicular Lymphoma, B-cell Malignancies, Mantle Cell Lymphoma, and Non-Hodgkin Lymphoma, among others.
Investigational
Matched Iupac: … 6-(1H-indazol-6-yl)-N-[4-(morpholin-4-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Esreboxetine

Esreboxetine has been used in trials studying the treatment and basic science of Fibromyalgia.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Etanidazole

Etanidazole has been used in trials studying the diagnostic of Adult Ependymoma, Malignant Ascites, Adult Gliosarcoma, Adult Mixed Glioma, and Adult Glioblastoma, among others.
Investigational
Matched Iupac: … N-(2-hydroxyethyl)-2-(2-nitro-1H-imidazol-1-yl)acetamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Apricitabine

Apricitabine has been used in trials studying the treatment of HIV Infections.
Investigational
Matched Iupac: … 4-amino-1-[(2R,4R)-2-(hydroxymethyl)-1,3-oxathiolan-4-yl]-1,2-dihydropyrimidin-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

LY-2334737

LY2334737 has been used in trials studying the treatment of Solid Tumor, Metastatic Tumor, and Malignant Solid Tumor.
Investigational
Matched Iupac: … N-{1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxo-1,2-dihydropyrimidin-4-yl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Serlopitant

Serlopitant has been investigated for the treatment of Prurigo Nodularis.
Investigational
Matched Iupac: … 3-[(3aR,4R,5S,7aS)-5-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-4-(4-fluorophenyl)-octahydro-1H-isoindol ... -2-yl]cyclopent-2-en-1-one …
Matched Categories: … Neurokinin-1 Receptor Antagonists …

Glycovir

Glycovir has been used in trials studying the treatment of HIV Infections.
Investigational
Matched Iupac: … [(2R,3R,4R,5S)-3,4,5-tris(butanoyloxy)-1-butylpiperidin-2-yl]methyl butanoate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Cinepazet

Experimental
Matched Iupac: … ethyl 2-{4-[(2E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]piperazin-1-yl}acetate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Morpholine

Experimental
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Fluzoparib

Fluzoparib is under investigation in clinical trial NCT03863860 (A Trial of Maintenance Treatment With Fluzoparib Versus Placebo in Relapsed Ovarian Cancer Patients).
Investigational
Matched Iupac: … 4-({4-fluoro-3-[2-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[1,5-a]pyrazine-7-carbonyl]phenyl}methyl ... )-1,2-dihydrophthalazin-1-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Monophosphothiamine

Experimental
Matched Iupac: … 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-5-[2-(phosphonooxy)ethyl]-1,3-thiazol-3-ium chloride …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Bentamapimod

Investigational
Matched Iupac: … 2-(1,3-benzothiazol-2-yl)-2-[2-({4-[(morpholin-4-yl)methyl]phenyl}methoxy)pyrimidin-4-yl]acetonitrile …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Modufolin

Modufolin is under investigation for the treatment of Osteosarcoma.
Investigational
Matched Iupac: … (2S)-2-({4-[(6aR)-3-amino-1-oxo-1H,2H,5H,6H,6aH,7H,8H,9H-imidazo[1,5-f]pteridin-8-yl]phenyl}formamido …

2-({6-[(3-Chlorophenyl)amino]-9-isopropyl-9H-purin-2-yl}amino)ethanol

Experimental
Matched Synonyms: … 2-(2-Hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine …
Matched Name: … 2-({6-[(3-Chlorophenyl)amino]-9-isopropyl-9H-purin-2-yl}amino)ethanol …
Matched Iupac: … 2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)-9H-purin-2-yl}amino)ethan-1-ol …

Cyclotheonamide A

Cyclotheonamide A is a cyclic peptide isolated from the marine sponge Theonella.
Experimental
Matched Iupac: … N-[(3S,7R,10S,16S,21aS)-7-benzyl-3-(3-carbamimidamidopropyl)-10-[(4-hydroxyphenyl)methyl]-1,4,5,8,13,17 …

4-Phospho-D-erythronohydroxamic acid

Experimental
Matched Name: … 4-Phospho-D-erythronohydroxamic acid …
Matched Iupac: … [(2R,3R)-2,3-dihydroxy-3-(hydroxycarbamoyl)propoxy]phosphonic acid …

Eribaxaban

Experimental
Matched Iupac: … (2R,4R)-N1-(4-chlorophenyl)-N2-[2-fluoro-4-(2-oxo-1,2-dihydropyridin-1-yl)phenyl]-4-methoxypyrrolidine …

Nizofenone

Experimental
Matched Iupac: … ({1-[2-(2-chlorobenzoyl)-4-nitrophenyl]-1H-imidazol-2-yl}methyl)diethylamine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

D-fluoromethyltyrosine F-18

D-fluoromethyltyrosine F-18 is under investigation in clinical trial NCT01089998 (PET/CT Imaging for Radiation Dosimetry, Plasma Pharmacokinetics, Safety and Tolerability in Healthy Volunteers and Safety, Tolerability and Diagnostic Performance of BAY86-9596 in Patients With Non-small Cell Lung Cancer, Breast Cancer, Head and Neck Cancer and Patients With Inflammations).
Investigational
Matched Iupac: … (2R)-2-amino-3-{4-[(¹⁸F)fluoromethoxy]phenyl}propanoic acid …

Rilotumumab

Rilotumumab has been investigated for the treatment of Cancer, Lung Cancer, Solid Tumors, Gastric Cancer, and Prostate Cancer, among others.
Investigational

Coronavirus-Like Particle COVID-19 Vaccine

The Coronavirus-Like Particle COVID-19 Vaccine is in development and testing through Meidcago in Quebec City, Canada. The vaccine was developed by creating SARS-Cov-2 virus-like particles (CoVLPs), which mimic the structure of the virus without carrying the genetic components required for infection. VLPs are thought to have multiple mechanisms involving the...
Investigational
Matched Description: … A Phase 1 clinical trial was launched in July 2020 evaluating the safety, tolerability, and immunogenicity …

Thymidine

Thymidine is a pyrimidine deoxynucleoside. Thymidine is the DNA nucleoside T, which pairs with deoxyadenosine (A) in double-stranded DNA. In cell biology it is used to synchronize the cells in S phase.
Experimental
Investigational
Matched Iupac: … 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Efatutazone

Efatutazone has been used in trials studying the treatment of Lymphoma, Liposarcoma, Solid Tumors, Multiple Myeloma, and Recurrent Thyroid Cancer, among others.
Investigational
Matched Iupac: … 5-[(4-{[6-(4-amino-3,5-dimethylphenoxy)-1-methyl-1H-1,3-benzodiazol-2-yl]methoxy}phenyl)methyl]-1,3-thiazolidine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 10176 - 10200 of 12310 in total