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Displaying drugs 10176 - 10200 of 12126 in total

Budipine

Experimental
Matched Iupac: … 1-tert-butyl-4,4-diphenylpiperidine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Nemiralisib

Nemiralisib is under investigation in clinical trial NCT03345407 (Dose Finding Study of Nemiralisib (GSK2269557) in Subjects With an Acute Moderate or Severe Exacerbation of Chronic Obstructive Pulmonary Disease (COPD)).
Investigational
Matched Iupac: … 6-(1H-indol-4-yl)-4-(5-{[4-(propan-2-yl)piperazin-1-yl]methyl}-1,3-oxazol-2-yl)-1H-indazole …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Pidnarulex

Investigational
Matched Iupac: … 4-(4-methyl-1,4-diazepan-1-yl)-N-[(5-methylpyrazin-2-yl)methyl]-8-oxo-11-thia-1,3-diazatetracyclo[8.7.0.0 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Ulixacaltamide

Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Recombinant Bacterial ACE2 Receptors-like Enzyme

B38-CAP is structured as a carboxypeptidase and derived from Paenibacillus sp. The molecule, an Angiotensin Converting Enzyme 2 (ACE2)-like enzyme, shares structural similarities to the mammalian ACE2. B38-CAP is an ACE2-like enzyme which decreases angiotensin II levels. It is being investigated for treating hypertension, myocardial fibrosis, and cardiac dysfunction.
Investigational

(2E)-3-(4-CHLOROPHENYL)-N-HYDROXYACRYLAMIDE

Experimental
Matched Name: … (2E)-3-(4-CHLOROPHENYL)-N-HYDROXYACRYLAMIDE …
Matched Iupac: … (2E)-3-(4-chlorophenyl)-N-hydroxyprop-2-enamide …

ETHYL 3-[4-(AMINOSULFONYL)PHENYL]PROPANOATE

Experimental
Matched Name: … ETHYL 3-[4-(AMINOSULFONYL)PHENYL]PROPANOATE …
Matched Iupac: … ethyl 3-(4-sulfamoylphenyl)propanoate …

N-(4-PHENYLAMINO-QUINAZOLIN-6-YL)-ACRYLAMIDE

Experimental
Matched Name: … N-(4-PHENYLAMINO-QUINAZOLIN-6-YL)-ACRYLAMIDE …
Matched Iupac: … N-[4-(phenylamino)quinazolin-6-yl]prop-2-enamide …

Autologous Non-Hematopoietic Peripheral Blood Stem Cells

Autologous non-hematopoietic peripheral blood stem cells have been created into a formulation for use in a clinical trial (NCT04473170) by the Abu Dhabi Stem Cells Center. The cells have the characterizations of CD90+, CD133+, Oct-4+, CD45-, and CD71-.
Investigational
Matched Description: … The cells have the characterizations of CD90+, CD133+, Oct-4+, CD45-, and CD71-.[L16363] …

Methionine sulfoximine

Experimental
Matched Synonyms: … (2S)-2-Amino-4-(S-methylsufonimidoyl)butanoic acid ... BUTANOIC ACID, 2-AMINO-4-(S-METHYLSULFONIMIDOYL)-, (2S)- …
Matched Iupac: … (2S)-2-amino-4-[imino(methyl)oxo-lambda6-sulfanyl]butanoic acid …

Bepranemab

Bepranemab is a recombinant humanized Igg4P monoclonal antibody directed against human Tau.
Investigational
Matched Synonyms: … Immunoglobulin g4 (226-proline), anti-(human tau protein) (human-rattus norvegicus monoclonal ucb0107 .gamma.4- …

2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,5-Diol

Experimental

N~3~-[3-(5-METHOXYPYRIDIN-3-YL)BENZYL]PYRIDINE-2,3-DIAMINE

Experimental
Matched Name: … N~3~-[3-(5-METHOXYPYRIDIN-3-YL)BENZYL]PYRIDINE-2,3-DIAMINE …
Matched Iupac: … N3-{[3-(5-methoxypyridin-3-yl)phenyl]methyl}pyridine-2,3-diamine …

N-(3,5-dimethoxyphenyl)imidodicarbonimidic diamide

Experimental
Matched Iupac: … 1-carbamimidamido-N-(3,5-dimethoxyphenyl)methanimidamide …

CYCLOHEXYLMETHYL-2,3-DIHYDROXY-5-METHYL-HEXYLAMIDE

Experimental
Matched Name: … CYCLOHEXYLMETHYL-2,3-DIHYDROXY-5-METHYL-HEXYLAMIDE …
Matched Iupac: … (2S,3R,4S)-2-amino-1-cyclohexyl-6-methylheptane-3,4-diol …

Facinicline

Investigational
Matched Iupac: … N-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-1H-indazole-3-carboxamide …
Matched Salts cas: … 677305-02-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Etiracetam

Etiracetam is under investigation in clinical trial NCT01137110 (Comparison of Short Duration Levetiracetam to Extended Course for Seizure Prophylaxis After Subarachnoid Hemorrhage (SAH)).
Investigational
Matched Iupac: … 2-(2-oxopyrrolidin-1-yl)butanamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Semagacestat

Semagacestat has been used in trials studying the treatment of Alzheimer Disease.
Investigational
Matched Iupac: … (2S)-2-hydroxy-3-methyl-N-[(1S)-1-{[(1S)-3-methyl-2-oxo-2,3,4,5-tetrahydro-1H-3-benzazepin-1-yl]carbamoyl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

BLZ-945

Investigational
Matched Iupac: … 4-[(2-{[(1R,2R)-2-hydroxycyclohexyl]amino}-1,3-benzothiazol-6-yl)oxy]-N-methylpyridine-2-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

CT-001

Investigational

NGX267

NGX267 is a muscarinic agonist. It is developed for the treatment of Alzheimer’s disease and has shown the potential to both reduce symptoms and slow disease progression.
Investigational
Matched Iupac: … (2S)-2-ethyl-8-methyl-1-thia-4,8-diazaspiro[4.5]decan-3-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Amdoxovir

Investigational
Matched Iupac: … [(2R,4R)-4-(2,6-diamino-9H-purin-9-yl)-1,3-dioxolan-2-yl]methanol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Metralindole

Metralindole, also known as Inkazan, is similar in structure and pharmacology to pirlindole. It functions as a reversible inhibitor of monoamine oxidase A. In Russia, this drug was investigated for potential antidepressant activity.
Experimental
Matched Iupac: … 12-methoxy-4-methyl-1,4,6-triazatetracyclo[7.6.1.0⁵,¹⁶.0¹⁰,¹⁵]hexadeca-5,9(16),10(15),11,13-pentaene …
Matched Salts cas: … 53734-79-5 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Misonidazole

Misonidazole is under investigation in clinical trial NCT00038038 (Assessment of Head and Neck Tumor Hypoxia Using 18F-Fluoromisonidazole).
Investigational
Matched Iupac: … 1-methoxy-3-(2-nitro-1H-imidazol-1-yl)propan-2-ol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Guadecitabine

Guadecitabine is under investigation for the treatment of Previously Treated Metastatic Colorectal Cancer.
Investigational
Matched Iupac: … {[(2R,3S,5R)-5-(4-amino-2-oxo-1,2-dihydro-1,3,5-triazin-1-yl)-2-(hydroxymethyl)oxolan-3-yl]oxy}({[(2R ... ,3S,5R)-5-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy})phosphinic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 10176 - 10200 of 12126 in total