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Displaying drugs 10226 - 10250 of 12330 in total

Miricorilant

Miricorilant is under investigation in clinical trial NCT03818256 (Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Miricorilant (CORT118335) in Obese Adult Patients With Schizophrenia and Recent Weight Gain While Taking Antipsychotic Medications (GRATITUDE)).
Investigational
Matched Iupac: … 6-[(1r,4r)-4-phenylcyclohexyl]-5-{[3-(trifluoromethyl)phenyl]methyl}-1,2,3,4-tetrahydropyrimidine-2,4 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Vafidemstat

Vafidemstat is under investigation in clinical trial NCT03867253 (Testing the Safety and Preliminary Efficacy of the New Drug ORY-2001 in Mild to Moderate Alzheimer's Disease).
Investigational
Matched Iupac: … 5-({[(1R,2S)-2-[4-(benzyloxy)phenyl]cyclopropyl]amino}methyl)-1,3,4-oxadiazol-2-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Furfural

Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Ampiroxicam

Investigational
Matched Iupac: … ethyl 1-({2-methyl-1,1-dioxo-3-[(pyridin-2-yl)carbamoyl]-2H-1lambda6,2-benzothiazin-4-yl}oxy)ethyl carbonate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Tianeptine

Tianeptine is a drug used primarily in the treatment of major depressive disorder and has been studied in the treatment of irritable bowel syndrome (IBS) . Structurally, it is classified as a tricyclic antidepressant (TCA), however, it possesses different pharmacological properties than typical tricyclic antidepressants . Tianeptine was discovered and...
Investigational
Matched Iupac: … 7-({6-chloro-10-methyl-9,9-dioxo-9lambda6-thia-10-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Phosphomethylphosphonic acid guanylate ester

Experimental
Matched Iupac: … ({[({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy …

N-DODECANOYL-L-TYROSINE

Experimental

Iodamide

Iodamide is a contrast medium molecule that is no longer marketed in the United States.
Withdrawn
Matched Iupac: … 3-acetamido-5-(acetamidomethyl)-2,4,6-triiodobenzoic acid …

Gantenerumab

Alzheimer's disease (AD) is the most common cause of dementia in elderly patients, with classical histopathological hallmarks including extracellular amyloid-beta (Aβ) plaques and intraneuronal neurofibrillary tangles (NFTs). As the classical view of AD pathology posits that Aβ accumulation triggers tau hyperphosphorylation and aggregation to form NFTs and cause neurodegeneration, large...
Investigational

Quinolinic Acid

A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS. [PubChem]
Experimental
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Tetomilast

Tetomilast has been used in trials studying the treatment of Crohn Disease, Colitis, Ulcerative, and Chronic Obstructive Pulmonary Disease.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Cardarine

Cardarine (GW-501516) is a peroxisome proliferator-activator receptor-delta agonist for the potential treatment of dyslipidemia. Cardarine has been investigated for the treatment of Obesity, Lipid Disorders, and Cardiovascular Disease.
Investigational
Matched Iupac: … 2-{2-methyl-4-[({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methyl)sulfanyl]phenoxy}acetic …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

CLX-0921

CLX-0921 is investigated for use/treatment in diabetes mellitus type 2. CLX-0921 is a solid. CLX-0921 has a spectrum of activity that differs from commercially available thiazolidinediones. This substance targets the protein peroxisome proliferator-activated receptor gamma. It is a pharmacologically active antihyperglycemic agent that acts by increasing peripheral tissue sensitivity to...
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

SNS-032

Investigational
Matched Iupac: … N-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-yl)piperidine-4-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Nipecotic acid

Experimental
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Uprosertib

Uprosertib has been used in trials studying the treatment of Cancer, Melanoma, Solid Tumours, Cervical Cancer, and HER2/Neu Negative, among others.
Investigational
Matched Iupac: … N-[(2S)-1-amino-3-(3,4-difluorophenyl)propan-2-yl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)furan …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Savolitinib

Savolitinib has been used in trials studying the treatment and health services research of Tumor, Food Effect, Gastric Cancer, Health Subjects, and Colorectal Cancer, among others.
Investigational
Matched Iupac: … 4-{1-[(1S)-1-{imidazo[1,2-a]pyridin-6-yl}ethyl]-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl}-1-methyl-1H-pyrazole …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

AZD-7762

AZD7762 has been investigated for the treatment of Cancer, Solid Tumors, and Advanced Solid Malignancies.
Investigational
Matched Iupac: … 3-(carbamoylamino)-5-(3-fluorophenyl)-N-[(3S)-piperidin-3-yl]thiophene-2-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

MBX-2982

MBX-2982 has been used in trials studying the treatment of Diabetes.
Investigational
Matched Iupac: … 5-ethyl-2-[4-(4-{[4-(1H-1,2,3,4-tetrazol-1-yl)phenoxy]methyl}-1,3-thiazol-2-yl)piperidin-1-yl]pyrimidine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Alagebrium

Alagebrium has been investigated for the treatment and prevention of Aging, Heart Failure, Physical Activity, Diabetic Nephropathy, and Cardiovascular Disease, among others.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Irdabisant

Irdabisant has been used in trials studying Cognitive Impairment.
Investigational
Matched Iupac: … 6-(4-{3-[(2R)-2-methylpyrrolidin-1-yl]propoxy}phenyl)-2,3-dihydropyridazin-3-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

JNJ-39220675

JNJ-39220675 has been used in trials studying the treatment of Allergic Rhinitis.
Investigational
Matched Iupac: … 1-cyclobutyl-4-[6-(4-fluorophenoxy)pyridine-3-carbonyl]-1,4-diazepane …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Penclomedine

Penclomedine has been used in trials studying the treatment of Lymphoma and Unspecified Adult Solid Tumor, Protocol Specific.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

PF-06751979

PF-06751979 is under investigation in clinical trial NCT03126721 (The Study is to Evaluate the Effect of Multiple Doses PF-06751979 on the Pharmacokinetics of Midazolam in Healthy Adults).
Investigational
Matched Iupac: … 4aR,6S,8aR)-2-amino-6-methyl-4H,4aH,5H,6H,8H,8aH-pyrano[3,4-d][1,3]thiazin-8a-yl]-1,3-thiazol-4-yl}-5- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Abeprazan

Abeprazan is under investigation in clinical trial NCT04341454 (Study to Evaluate the Efficacy and Safety of DWP14012 in Patients With Acute or Chronic Gastritis).
Investigational
Matched Iupac: … {[5-(2,4-difluorophenyl)-1-(3-fluorobenzenesulfonyl)-4-methoxy-1H-pyrrol-3-yl]methyl}(methyl)amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 10226 - 10250 of 12330 in total