Displaying drugs 10401 - 10425 of 14692 in total
Ncs-Chromophore
Experimental
Cefatrizine
Experimental
Cefsulodin
Experimental
D-Treitol
A four-carbon sugar that is found in algae, fungi, and lichens. It is twice as sweet as sucrose and can be used as a coronary vasodilator. [PubChem]
Experimental
Matched Description: … A four-carbon sugar that is found in algae, fungi, and lichens. ... It is twice as sweet as sucrose and can be used as a coronary vasodilator. [PubChem] …
SB-249553
SB-249553 is a vaccine that has MAGE-3 cancer antigen and the Adjuvant SBAS-2. It is also under by GlaxoSmithKline to treat melanoma and lung cancer.
Investigational
Matched Description: … It is also under by GlaxoSmithKline to treat melanoma and lung cancer. ... SB-249553 is a vaccine that has MAGE-3 cancer antigen and the Adjuvant SBAS-2. …
3,3'-diindolylmethane
Diindolylmethane has been used in trials studying the prevention and treatment of SLE, Prostate Cancer, Cervical Dysplasia, Stage I Prostate Cancer, and Stage II Prostate Cancer, among others.
Investigational
Matched Description: … , Cervical Dysplasia, Stage I Prostate Cancer, and Stage II Prostate Cancer, among others. ... Diindolylmethane has been used in trials studying the prevention and treatment of SLE, Prostate Cancer …
Florzolotau F-18
PMPBB3 F-18 is under investigation in clinical trial NCT04305210 (Alzheimer's Disease: Clinical Investigation and Neuroimage Studies Including 18F-PM-PBB3 and 18f-florbetapir (AV-45) PET Examination).
Investigational
Matched Description: … Neuroimage Studies Including 18F-PM-PBB3 and 18f-florbetapir (AV-45) PET Examination). ... 18 is under investigation in clinical trial NCT04305210 (Alzheimer's Disease: Clinical Investigation and …
Stem-cell derived exosome vesicle products
Mesenchymal stem cells (MSCs) exert their therapeutic effects through multiple modalities, including paracrine factors such as exosomes. Exosomes are nanometer-sized, membrane-bound vesicles secreted for the purpose of cell-cell communication. Once secreted into extracellular fluid, exosomes are taken up by their target cells or carried to distant target sites. Various bioactive...
Investigational
Matched Description: … and tissue repair. ... Exosomes from MSCs carry cytokines and growth factors, like TGFB1, IL-6, IL-10, and hepatocyte growth ... Various bioactive molecules (including lipids, proteins, mRNAs, and tRNAs) are used to enrich exosomes …
P54
P54 reduces the inflammation associated with cancer/tumors, Crohn's disease, inflammatory bowel disease, osteoarthritis, and ulcerative colitis. It inhibits the induction of the enzyme NFkB, thereby inhibiting downstream inflammatory genes such as COX II and iNOS.
Investigational
Matched Description: … inflammation associated with cancer/tumors, Crohn's disease, inflammatory bowel disease, osteoarthritis, and ... inhibits the induction of the enzyme NFkB, thereby inhibiting downstream inflammatory genes such as COX II and …
Arylacenamide
Arylacenamide (SR31747) is a peripheral [sigma] ligand that binds four proteins in human cells, i.e. SRBP-1, [sigma]-2, HSI and its relative SRBP-2. It is a dual agent with both immunomodulatory and antiproliferative activities.
Investigational
Matched Description: … SRBP-1, [sigma]-2, HSI and its relative SRBP-2. ... It is a dual agent with both immunomodulatory and antiproliferative activities. …
1,6-Fructose Diphosphate (Linear Form)
Experimental
Filaminast
Filaminast is a phosphodiesterase 4 inhibitor (PDE4 inhibitor). As such, has potential in the treatment of asthma and chronic obstructive pulmonary disease (COPD).
Experimental
Matched Description: … As such, has potential in the treatment of asthma and chronic obstructive pulmonary disease (COPD). …
alpha-L-iduronic acid
Experimental
Fructose-6-phosphate
Experimental
[4,6-O-(1-CARBOXYETHYLIDENE)-BETA-D-MANNOSE]
Experimental
Agmatine
Agmantine is a natural metabolite of the amino acid arginine. It is formed when arginine is decarboxylated by the enzyme arginine decarboxylase and is found naturally in ragweed pollen, ergot fungi, octopus muscle, herring sperm, sponges, and the mammalian brain. Agmatine is both an experimental and investigational drug. As an...
Experimental
Matched Description: … neuropathic pain), and psychiatric conditions (depression, anxiety, schizophrenia, and cognition). ... Agmatine is both an experimental and investigational drug. ... in ragweed pollen, ergot fungi, octopus muscle, herring sperm, sponges, and the mammalian brain. …
PRTX-100
PRTX-100 is a highly-purified form of Staphylococcal Protein A that binds directly to monocytes and a subset of B-cells that are involved in the development and progression of various autoimmune diseases. These binding interactions enable the compound to modulate the function of these cells and restore the balance of the...
Investigational
Matched Description: … PRTX-100 is a highly-purified form of Staphylococcal Protein A that binds directly to monocytes and a ... subset of B-cells that are involved in the development and progression of various autoimmune diseases ... These binding interactions enable the compound to modulate the function of these cells and restore the …
Methaqualone
Methaqualone is a sedative-hypnotic drug that is similar in effect to barbiturates, a general central nervous system depressant. The sedative-hypnotic activity was first noted by Indian researchers in the 1950s and in 1962 methaqualone itself was patented in the US by Wallace and Tiernan. Its use peaked in the early...
Illicit
Withdrawn
Matched Description: … itself was patented in the US by Wallace and Tiernan. ... The sedative-hypnotic activity was first noted by Indian researchers in the 1950s and in 1962 methaqualone ... Its use peaked in the early 1970s as a hypnotic, sedative, and muscle relaxant commonly used for insomnia …
Matched Categories: … Hypnotics and Sedatives …
Matched Categories: … Hypnotics and Sedatives …
CTA018
CTA018 is a member of a new class of vitamin D analogues with a dual mechanism of action, called Vitamin D Signal Amplifiers. This proprietary new drug is both a potent inhibitor of CYP24 (the enzyme responsible for the breakdown of vitamin D) and a potent activator of vitamin D...
Investigational
Matched Description: … calcipotriol and it is expected to have a greater safety index. ... new drug is both a potent inhibitor of CYP24 (the enzyme responsible for the breakdown of vitamin D) and ... inhibits the proliferation of rapidly dividing cells such as human epidermal keratinocytes (skin cells) and …
ACE393
ACE393 is an injectable vaccine designed to combat the bacterium Campylobacter jejuni, one of the greatest causes of bacterial diarrhoeal infections in the developed world.
Investigational
rhMBL
rhMBL is a protein therapeutic being developed by Enzon for the prevention and treatment of severe infections in individuals with low levels of Mannose-Binding Lectin (MBL). Over 10 percent of the general population is estimated to be MBL-deficient. Natural MBL is a 400-700kDa oligomer made of 3 identical 32kDa peptide...
Investigational
Matched Description: … rhMBL is a protein therapeutic being developed by Enzon for the prevention and treatment of severe infections …
Displaying drugs 10401 - 10425 of 14692 in total