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Displaying drugs 1026 - 1050 of 1233 in total

Osimertinib

Osimertinib is an oral, third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) drug developed by AstraZeneca Pharmaceuticals.[A7926,L43453] Its use is indicated for the treatment of metastatic non-small cell lung cancer (NSCLC) in cases where tumour EGFR expression is positive for the T790M mutation as detected by FDA-approved testing...
Approved
Matched Description: … where tumour EGFR expression is positive for the T790M mutation as detected by FDA-approved testing and ... Approximately 10% of patients with NSCLC have a rapid and clinically effective response to EGFR-TKIs ... [A7927] More specifically, deletions around the LREA motif in exon 19 and exon 21 L858R point mutations …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Tagrisso Film-Coated Tablet 40mg ... Tagrisso Film-Coated Tablet 80mg ... TAGRİSSO 40 MG FİLM KAPLI TABLET …

Fimasartan

Fimasartan is an angiotensin II receptor antagonist (ARB) drug employed in the treatment of both hypertension and heart failure. It has been found to be safe when administered with hydrochlorothiazide (a diuretic) in clinical trials. Fimasartan was initially approved September 9th, 2010 in South Korea and is marketed under the...
Investigational
Matched Description: … is an angiotensin II receptor antagonist (ARB) drug employed in the treatment of both hypertension and ... Fimasartan was initially approved September 9th, 2010 in South Korea and is marketed under the brand …
Matched Mixtures name: … ARAHKOR - PRE …
Matched Categories: … Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... Angiotensin II receptor blockers (ARBs) and diuretics ... fimasartan and diuretics ... fimasartan and amlodipine ... rosuvastatin and fimasartan …
Matched Products: … Kanarb Film-Coated Tablets 60mg ... Kanarb Film-Coated Tablets 120mg ... KANARB®PLUS FILM COATED TABLETS 60 MG/12.5 MG …

Dexibuprofen

Dexibuprofen, S(+)-ibuprofen, is a non-steroidal anti-inflammatory drug (NSAID). It is a pharmacologically effective enantiomer of racemic ibuprofen that differs in physicochemical properties. It is proposed to be more pharmacologically active and tolerable with a better safety profile than ibuprofen due to higher concentration of active S enantiomer. Dexibuprofen has a...
Approved
Investigational
Matched Description: … the racemic ibuprofen and displays improved oral bioavilability [A19259]. ... It is proposed to be more pharmacologically active and tolerable with a better safety profile than ibuprofen ... Dexibuprofen has a slower dissolution rate in the simulated gastric and enteric juices compared with …
Matched Categories: … Ibuprofen and isomer ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … IBUDEX 400 FILM TABLET, 10 ADET ... IBUDEX 400 FILM TABLET, 30 ADET ... IBUDEX 400 MG FILM TABLET, 20 ADET …

Fesoterodine

Fesoterodine is an antimuscarinic prodrug for the treatment of overactive bladder syndrome.
Approved
Matched Categories: … Drugs for Urinary Frequency and Incontinence ... Genito Urinary System and Sex Hormones …
Matched Products: … FOSETAZ 4 MG UZATILMIŞ SALIMLI FİLM KAPLI TABLET, 14 ADET ... FOSETAZ 4 MG UZATILMIŞ SALIMLI FİLM KAPLI TABLET, 28 ADET ... FOSETAZ 4 MG UZATILMIŞ SALIMLI FİLM KAPLI TABLET, 84 ADET …

Sertindole

Sertindole, a neuroleptic, is one of the newer antipsychotic medications available. Serdolect is developed by the Danish pharmaceutical company H. Lundbeck. It is a phenylindole derivative used in the treatment of schizophrenia. It was first marketed in 1996 in several European countries before being withdrawn two years later because of...
Approved
Investigational
Withdrawn
Matched Description: … It has once again been approved and should soon be available on the French and Australian market. …
Matched Products: … SERDOLECT 4 MG FILM KAPLI TABLET, 30 ADET ... SERDOLECT 12 MG FILM KAPLI TABLET, 28 ADET ... SERDOLECT 16 MG FILM KAPLI TABLET, 28 ADET …

Ursodeoxycholic acid

Ursodeoxycholic acid (UDCA), also known as ursodiol, is a naturally-occurring bile acid that constitutes a minor fraction of the human bile acid pool.[A256272,A256277] UDCA has been used to treat liver disease for decades: its first use in traditional medicine dates back more than a hundred years.[A256267,A256463] UDCA was first characterized...
Approved
Investigational
Matched Description: … [A256267,A256463] UDCA was first characterized in the bile of the Chinese black bear and is formed by ... [A256272] UDCA was first approved by the FDA in 1987 for dissolution of gallstones and for primary …
Matched Categories: … Alimentary Tract and Metabolism ... Bile acids and derivatives ... Bile Acids and Salts ... Bile and Liver Therapy ... Cholagogues and Choleretics …
Matched Products: … URSOKOL 250 MG FILM TABLET,100 ADET ... URSOKOL 500 MG FILM TABLET,100 ADET ... URSOKOL 750 MG FİLM TABLET, 50 ADET …

Moxonidine

Moxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild to moderate essential hypertension. It is suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and calcium channel blockers are not appropriate or irresponsive. As well, moxonidine has been shown...
Approved
Investigational
Matched Description: … suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and ... calcium channel blockers are not appropriate or irresponsive. …
Matched Categories: … moxonidine and diuretics …
Matched Products: … MOXONIDIN - CT 0.2MG FILM ... MOXONIDIN - CT 0.3MG FILM ... MOXONIDIN - CT 0.4MG FILM …

Letrozole

Letrozole, or CGS 20267, is an oral non-steroidal type II aromatase inhibitor first described in the literature in 1990.[A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like exemestane and anastrozole, meaning it does not significantly affect cortisol, aldosterone, and thyroxine. Letrozole was granted FDA approval on 25 July 1997.
Approved
Investigational
Matched Description: … ], meaning it does not significantly affect cortisol, aldosterone, and thyroxine. ... [A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like [exemestane] and [anastrozole …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Mar-letrozole ... Letara Film Coated Tablet 2.5mg ... Trozet Film Coated Tablet 2.5mg …

Lacosamide

Lacosamide is an antiepileptic drug used to treat seizures. As a chiral functionalized amino acid, it works by blocking slowly inactivating components of voltage-gated sodium currents. Lacosamide exhibits a stereoselective mode of interaction with sodium channels. Lacosamide was first approved by the European Commission in August 2008 and was later...
Approved
Matched Description: … [A262681] Lacosamide was first approved by the European Commission in August 2008 and was later approved …
Matched Products: … Mar-lacosamide ... VIMPAT 50 MG (FILM-COATED TABLETS) ... VIMPAT 100 MG (FILM-COATED TABLETS) …

Neratinib

Neratinib was approved in July 2017 for use as an extended adjuvant therapy in Human Epidermal Growth Factor Receptor 2 (HER2) positive breast cancer. Approval was granted to Puma Biotechnology Inc. for the tradename Nerlynx. Neratinib is currently under investigation for use in many other forms of cancer.
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … NERLYNX FILM-COATED TABLETS 40 MG ... NERLYNX (neratinib) Film-Coated Tablets 40 mg …

Aceclofenac

Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It is reported to have a higher anti-inflammatory action or at least comparable effects than conventional NSAIDs in double-blind studies [A19667, A19668, A19670]. Aceclofenac potently inhibits the...
Approved
Investigational
Matched Description: … Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and ... analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. ... synthesis of prostaglandins, which are inflammatory mediators that cause pain, swelling, inflammation, and …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Matched Products: … AIRTAL FILM COATED TABLETS 100mg ... Airtal 100mg Film-coated Tablet ... ASEC 100 MG FILM TABLET, 20 ADET …

Sofosbuvir

Sofosbuvir (tradename Sovaldi) is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the...
Approved
Matched Description: … for its high replicative rate and genetic diversity [A19594]. ... count, and neuropsychiatric effects [A19635]. ... categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and …
Matched Mixtures name: … Ledipasvir and Sofosbuvir ... Sofosbuvir and Velpatasvir ... VOSEVI FILM-COATED TABLETS 400MG/100MG/100MG …
Matched Categories: … sofosbuvir and ledipasvir ... sofosbuvir and velpatasvir ... Nucleic Acids, Nucleotides, and Nucleosides ... sofosbuvir, velpatasvir and voxilaprevir …
Matched Products: … Sovaldi 400mg Film-Coated Tablets ... GRATEZIANO 400 MG FILM COATED TABLET ... SOVALDI 400 MG FILM KAPLI TABLET, 84 ADET …

Abrocitinib

Abrocitinib is an oral small-molecule inhibitor of Janus kinase 1 (JAK1). Janus kinases are intracellular enzymes involved in transduction pathways that regulate hematopoiesis and immune cell function. The Janus kinase (JAK)–signal transducer and activator of transcription (STAT) signalling pathway plays a central role in the pathogenesis of a variety of...
Approved
Investigational
Matched Description: … Janus kinases are intracellular enzymes involved in transduction pathways that regulate hematopoiesis and ... [L39774] The Janus kinase (JAK)–signal transducer and activator of transcription (STAT) signalling pathway ... plays a central role in the pathogenesis of a variety of autoimmune and inflammatory diseases, including …
Matched Products: … CİBİNQO 50 MG FİLM KAPLI TABLET, 28 ADET ... CİBİNQO 200 MG FİLM KAPLI TABLET, 28 ADET ... CİBİNQO 100 MG FİLM KAPLI TABLET, 28 ADET …

Enoxacin

A broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.
Approved
Investigational
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Matched Products: … REKSOTİN 200 MG FİLM TABLET, 6 TABLET ... REKSOTİN 400 MG FİLM TABLET, 14 TABLET …

Luseogliflozin

Luseogliflozin has been used in trials studying the treatment of Diabetes Melltius, Type 2.
Investigational
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Lusefi 5mg film-coated tablet ... Lusefi 2.5mg film-coated tablet …

Diosmin

Chronic venous insufficiency is a common condition the western population. Compression and pharmacotherapy are frequently used to manage chronic venous insufficiency, improving circulation and symptoms of venous disease. Diosmin is a bioflavonoid isolated from various plants or synthesized from hesperidin. It is used for the improvement of capillary fragility or...
Approved
Investigational
Matched Description: … circulation and symptoms of venous disease. ... Compression and pharmacotherapy are frequently used to manage chronic venous insufficiency, improving ... improvement of capillary fragility or venous insufficiency, including chronic venous insufficiency (CVI) and …
Matched Mixtures name: … VENAFIX (Diosmin and Hesperidin Tablet) ... Davmorid Film Coated Tablet ... DIOSPER FILM COATED TABLET …
Matched Products: … DAFLON FILM-COATED TABLET 1000 mg ... RUVENTIN FILM COATED TABLET 500MG ... DAFLON 500 MG FILM TABLET, 60 ADET …

Vemurafenib

Vemurafenib is a competitive kinase inhibitor with activity against BRAF kinase with mutations like V600E. It exerts its function by binding to the ATP-binding domain of the mutant BRAF. Vemurafenib was co-developed by Roche and Plexxikon and it obtained its FDA approval on August 17, 2011, under the company Hoffmann...
Approved
Matched Description: … [A31270] Vemurafenib was co-developed by Roche and Plexxikon and it obtained its FDA approval on August …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … ZELBORAF 240 MG FILM KAPLI TABLET ,56 FILM KAPLI TABLET ... Zelboraf 240mg film-coated tablets …

Zolmitriptan

Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)1B/1D/(1F) receptor agonists used to treat acute migraine.[A462, L12978] Sumatriptan was the first triptan to be developed, but had poor oral bioavailability and lipophilicity. This led to the development of second-generation triptans, including almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, and zolmitriptan. Triptans...
Approved
Investigational
Matched Description: … A462, L12978] [Sumatriptan] was the first triptan to be developed, but had poor oral bioavailability and ... It is currently available in both tablet and nasal spray forms.[L12978] ... [A193791] Triptans can be administered alone or in combination with an NSAID like [naproxen], and represent …
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Products: … Mar-zolmitriptan ... MIGTERA 5 MG FİLM TABLET, 2 ADET ... MIGTERA 5 MG FİLM TABLET, 3 ADET …

Vardenafil

Vardenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) and an oral therapy for the treatment of erectile dysfunction.[L45563,L45568] During sexual stimulation, nitric oxide (NO) is released from nerve endings and endothelial cells in the corpus cavernosum, activating the enzyme guanylate cyclase and increasing the...
Approved
Matched Description: … selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) and ... [L45563,L45568] During sexual stimulation, nitric oxide (NO) is released from nerve endings and endothelial ... cells in the corpus cavernosum, activating the enzyme guanylate cyclase and increasing the synthesis …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … VAREKSİL 5 MG FİLM KAPLI TABLET, 4 ADET ... VAREKSİL 10 MG FİLM KAPLI TABLET, 4 ADET ... VAREKSİL 20 MG FİLM KAPLI TABLET, 2 ADET …

Tolterodine

Tolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.
Approved
Investigational
Matched Description: … Tolterodine acts on M2 and M3 subtypes of muscarinic receptors. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Matched Products: … TOLTEX 2 MG FILM TABLET, 28 ADET ... TOLTEX FİLM 1 MG TABLET , 28 ADET ... URIDYN 1 MG FILM TABLET ,28 ADET …

Asciminib

Asciminib is a tyrosine kinase inhibitor (TKI) used in the treatment of chronic-phase Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML). More specifically, it is an inhibitor of the ABL1 kinase activity of the BCR-ABL1 fusion protein which serves as a driver of CML proliferation in most patients with the disease....
Approved
Investigational
Matched Description: … Existing inhibitors of ABL compete at the ATP binding sites of these proteins and can be classified into ... those that target the active conformation of the kinase domain ([dasatinib], [bosutinib]) and those ... in that it acts as an allosteric inhibitor, binding at the myristoyl pocket of the BCR-ABL1 protein and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … AZEVAY 20 MG FİLM KAPLI TABLET , 60 ADET ... AZEVAY 40 MG FİLM KAPLI TABLET , 60 ADET …

Finasteride

Finasteride is a synthetic 4-azasteroid compound and specific inhibitor of steroid Type II 5α-reductase, which is an intracellular enzyme that converts the androgen testosterone into 5α-dihydrotestosterone (DHT). It works in a similar fashion as dutasteride, which is another 5-alpha-reductase inhibitor, by exerting antiandrogenic effects. Finasteride is an orally active drug...
Approved
Matched Description: … Finasteride is a synthetic 4-azasteroid compound [L10565] and specific inhibitor of steroid Type II 5α-reductase ... first approved by the FDA in 1992 for the treatment of benign prostatic hyperplasia to improve symptoms and ... [L6244] Finasteride is commonly marketed under the brand names Propecia and Proscar to be used aloneo …
Matched Categories: … doxazosin and finasteride ... Skin and Mucous Membrane Agents ... alfuzosin and finasteride ... Genito Urinary System and Sex Hormones ... finasteride and tadalafil …
Matched Products: … FINASTERID - CT 5MG FILM ... FINASTERID ARISTO 5MG FILM ... FINARID 5 MG FİLM TABLET, 30 ADET …

Bisoprolol

Bisoprolol is a cardioselective β1-adrenergic blocking agent used to treat high blood pressure.[A180472,L7219] It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs. Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor...
Approved
Matched Description: … A180472] Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor selectivity and ... alternative to non-selective β-blocker drugs in the treatment of hypertension such as [Carvedilol] and ... It may be used alone or in combination with other drugs to manage hypertension[L7219] and can be useful …
Matched Mixtures name: … KARDORITM PLUS 10 MG/25 MG FILM TABLET ,FILM TABLET, 30 ADET ... Cosyrel 5mg/5mg film-coated tablets ... Cosyrel 5mg/10mg film-coated tablets …
Matched Categories: … Beta blocking agents and calcium channel blockers ... Beta Blocking Agents and Thiazides ... ramipril and bisoprolol ... bisoprolol and thiazides ... perindopril and bisoprolol …
Matched Products: … Concor 5mg Film coated Tablet ... ADROTEN FILM-COATED TABLET 5MG ... Concor 10mg Film coated Tablet …

Vilazodone

Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. Vilazodone may also be associated with less sexual dysfunction and weight gain . Vilazodone was given FDA approval on January 21, 2011[L6046,A177622].
Approved
Matched Description: … (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. ... Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine ... Vilazodone may also be associated with less sexual dysfunction and weight gain[A6947]. …
Matched Categories: … Serotonin antagonist and reuptake inhibitors (SARIs) …
Matched Products: … ZİLADONE 10 MG FİLM KAPLI TABLET, 30 ADET ... ZİLADONE 20 MG FİLM KAPLI TABLET, 30 ADET ... ZİLADONE 40 MG FİLM KAPLI TABLET, 30 ADET …

Piracetam

Piracetam is a nootropic drug in the racetams group, with chemical name 2-oxo-1-pyrrolidine acetamide. It shares the same 2-oxo-pyrrolidone base structure with pyroglutamic acid and is a cyclic derivative of the neurotransmitter γ-aminobutyric acid (GABA). However its mechanism of action differ from that of endogenous GABA. Piracetam has neuroprotective and...
Approved
Investigational
Matched Description: … Piracetam has neuroprotective and anticonvulsant properties and is reported to improve neural plasticity ... It shares the same 2-oxo-pyrrolidone base structure with pyroglutamic acid and is a cyclic derivative ... Its efficacy is documented in cognitive disorders and dementia, vertigo, cortical myoclonus, dyslexia …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … KNOWFUL FILM COATED TABLET 800MG ... Ceretam 800mg Film-Coated Tablet ... KNOFUL (FILM COATED TABLET 800 MG) …
Displaying drugs 1026 - 1050 of 1233 in total