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Displaying drugs 1026 - 1050 of 1294 in total
Experimental
Matched Name: … [4,6-O-(1-CARBOXYETHYLIDENE)-BETA-D-MANNOSE] …
Experimental
Matched Name: … PARA-NITROPHENYL 1-THIO-BETA-D-GLUCOPYRANOSIDE …
Teniposide is a semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Teniposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent cells from entering into the mitotic...
Approved
Matched Synonyms: … 4'-demethylepipodophyllotoxin 9-(4,6-O-(R)-2-thenylidene-beta-D-glucopyranoside) …
Matched Description: … Teniposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. ... Teniposide acts primarily in the G2 and S phases of the cycle. ... This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Experimental
Matched Synonyms: … L-Threo-alpha,beta-diaminobutyric acid …
Experimental
Matched Synonyms: … 5-beta-DHT ... etiocholan-17-beta-ol-3-one …
Matched Categories: … Testosterone and derivatives …
Molibresib is under investigation in clinical trial NCT01943851 (A Dose Escalation Study to Investigate the Safety, Pharmacokinetics (PK), Pharmacodynamics (PD) and Clinical Activity of GSK525762 in Subjects With Relapsed, Refractory Hematologic Malignancies).
Investigational
Matched Synonyms: … Bet inhibitor gsk525762 …
Matched Description: … NCT01943851 (A Dose Escalation Study to Investigate the Safety, Pharmacokinetics (PK), Pharmacodynamics (PD) and
An acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
Approved
Investigational
Matched Salts name: … Ganciclovir sodium
Matched Categories: … Ganciclovir and prodrug ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … GANCICLOVIR SODIUM FOR INJECTION …
Polyvinyl alcohol is a water-soluble synthetic polymer obtained by polymerization of vinyl alcohol. It has varying roles in commercial and industrial applications such as papermaking, textiles, and printing. Polyvinyl alcohol is found in ophthalmic solutions as a lubricant to prevent irritation or to relieve dryness of the eyes .
Approved
Matched Description: … It has varying roles in commercial and industrial applications such as papermaking, textiles, and printing …
Matched Mixtures name: … OQ-SEE ® ... OQ-SEE ® …
Matched Products: … Major LiquiTears …
Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is a nonsteroidal anti-inflammatory drug (NSAID) which is known for its decreased risk of causing gastrointestinal bleeding compared to other NSAIDS. It is used to manage symptoms of various types of arthritis pain and in familial adenomatous polyposis (FAP) to reduce precancerous polyps in...
Approved
Investigational
Matched Description: … [A181544] It is used to manage symptoms of various types of arthritis pain and in familial adenomatous ... [A181532] It is marketed by Pfizer under the brand name Celebrex, and was initially granted FDA approval ... selective COX-2 inhibitors (especially celecoxib), have been evaluated as potential cancer chemopreventive and
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antineoplastic and Immunomodulating Agents ... tramadol and celecoxib ... amlodipine and celecoxib ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … CELECOXIB BETA 100MG ... CELECOXIB BETA 200MG …
Investigational
Matched Synonyms: … 4-nitrophenyl-n-acetyl-beta-d-glucosaminide ... 4-nitrophenyl 2-acetamido-2-deoxy-beta-d-glucopyranoside ... .beta.-d-glucopyranoside, 4-nitrophenyl 2-(acetylamino)-2-deoxy- …
An irreversible cholinesterase inhibitor with actions similar to those of echothiophate. It is a powerful miotic used mainly in the treatment of glaucoma. Its vapor is highly toxic and it is recommended that only solutions in arachis oil be used therapeutically. (From Martindale, The Extra Pharmacopoeia, 29th ed, p1330)
Approved
Investigational
Withdrawn
Matched Synonyms: … O,O'-diisopropyl phosphoryl fluoride …
Matched Description: … Its vapor is highly toxic and it is recommended that only solutions in arachis oil be used therapeutically …
Azacitidine is a pyrimidine nucleoside analogue with anti-neoplastic activity. It differs from cytosine by the presence of nitrogen in the C5-position, key in its hypomethylating activity.[A1406,A1413,A1415] Two main mechanisms of action have been proposed for azacitidine. One of them is the induction of cytotoxicity. As an analogue of cytidine, it...
Approved
Investigational
Matched Synonyms: … 4-amino-1-beta-D-ribofuranosyl-s-triazin-2(1H)-one …
Matched Description: … As an analogue of cytidine, it is able to incorporate into RNA and DNA, disrupting RNA metabolism and ... inhibiting protein and DNA synthesis. ... [A1407] Due to its anti-neoplastic activity and its ability to inhibit methylation in replicating DNA …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Experimental
Matched Synonyms: … 2-deoxy-beta-D-galactose …
Experimental
Matched Name: … beta-phenyl-D-phenylalanyl-N-propyl-L-prolinamide …
Celastrol is a pentacyclic triterpenoid isolated from the root extracts of Tripterygium wilfordii.
Investigational
Matched Synonyms: … .,14.beta.,20.alpha ... 24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-9,13-dimethyl-2-oxo-, (9.beta.,13.alpha …
Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist used for the treatment of severe pain.[A186283,A186292] It is also commonly used as an alternative to methadone for the treatment of severe opioid addiction. Buprenorphine is commercially available as the brand name product Suboxone which is...
Approved
Illicit
Investigational
Vet approved
Matched Description: … Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist ... who require larger and more frequent doses. ... an improved safety profile with a lower risk of overdose and respiratory depression. …
Matched Mixtures name: … Buprenorphine HCl and Naloxone HCl ... Buprenorphine and Naloxone ... Buprenorphine and Naloxone …
Matched Products: … BUPRENORPHIN BETA 35UG/H ... BUPRENORPHIN BETA 70UG/H ... BUPRENORPHIN BETA 52.5UG/H …
Experimental
Matched Synonyms: … Endo-1,4-beta-xylanase A …
Matched Categories: … Enzymes and Coenzymes …
Venlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). Its active metabolite, desvenlafaxine, works by blocking the reuptake of serotonin and norepinephrine, which are key neurotransmitters in mood regulation. Venlafaxine is officially approved to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder, and...
Approved
Matched Description: … Venlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). ... Venlafaxine is officially approved to treat major depressive disorder (MDD), generalized anxiety disorder ... (GAD), social anxiety disorder, and panic disorder in adults. …
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors …
Matched Products: … VENLAFAXIN BETA 37.5MG ... VENLAFAXIN BETA RET 75MG ... VENLAFAXIN BETA RET 150MG …
Experimental
Matched Name: … 2'-Deoxyuridine 5'-alpha,beta-imido-triphosphate …
Matched Iupac: … )amino](hydroxy)phosphoryl}oxy)phosphonic acid ... [({[(2R,3S,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl
Experimental
Matched Name: … C-(1-hydrogyl-beta-D-glucopyranosyl) formamide …
Experimental
Matched Name: … 4-Deoxy-4-Amino-Beta-D-Glucose …
Experimental
Matched Name: … 1-deoxy-1-methoxycarbamido-beta-D-glucopyranose …
Experimental
Matched Name: … 5-ALPHA-PREGNANE-3-BETA-OL-HEMISUCCINATE …
Esculin is found in barley. Vitamin C2 is generally considered a bioflavanoid, related to vitamin P esculin is a glucoside that naturally occurs in the horse chestnut (Aesculus hippocastanum), California Buckeye (Aesculus californica) and in daphnin (the dark green resin of Daphne mezereum). Esculin belongs to the family of Glycosyl...
Approved
Matched Synonyms: … 6-(beta-D-Glucopyranosyloxy)-7-hydroxy-cumarin ... 6-(beta-D-Glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one …
Matched Description: … naturally occurs in the horse chestnut (Aesculus hippocastanum), California Buckeye (Aesculus californica) and
Matched Salts name: … Esculin sodium
Investigational
Matched Synonyms: … Chelidoninium, 5,5',5''-(phosphinothioylidynetris(imino-2,1-ethanediyl))tris(5-methyl- …
Displaying drugs 1026 - 1050 of 1294 in total