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Displaying drugs 1026 - 1050 of 1345 in total

Tranexamic acid

Tranexamic acid is a synthetic derivative of lysine used as an antifibrinolytic in the treatment and prevention of major bleeding. It possesses a similar mechanism of action to aminocaproic acid but is approximately 10-fold more potent. It was first patented in 1957 and received its initial US approval in 1986.
Approved
Matched Synonyms: … trans-4-aminomethylcyclohexane-1-carboxylic acid …
Matched Iupac: … (1r,4r)-4-(aminomethyl)cyclohexane-1-carboxylic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …

Cinchocaine

A local anesthetic of the amide type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted to spinal anesthesia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1006)
Approved
Vet approved
Matched Synonyms: … 2-butoxyquinoline-4-carboxylic acid diethylaminoethylamide ... 2-Butoxy-quinoline-4-carboxylic acid (2-diethylamino-ethyl)-amide …
Matched Iupac: … 2-butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide …
Matched Categories: … Cardiovascular System …

Salsalate

Salsalate is a nonsteroidal anti-inflammatory agent for oral administration. Salsalate's mode of action as an anti-inflammatory and antirheumatic agent may be due to inhibition of synthesis and release of prostaglandins. The usefulness of salicylic acid, the active in vivo product of salsalate, in the treatment of arthritic disorders has been...
Approved
Matched Synonyms: … 2-Carboxyphenyl salicylate …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …

Lotilaner

Lotilaner is an ectoparasiticide that is a member of the isoxazoline family of compounds. Lotilaner has largely been used for veterinary uses as an antiparasitic agent to treat flea and tick infestations in animals.[A260746, L47556] Lotilaner consists of two enantiomers: the S-enantiomer is active in vivo, while the R-enantiomer is...
Approved
Vet approved
Matched Synonyms: … ethyl)-5-((55)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl)thiophene-2-carboxamide …

Cephaloglycin

A cephalorsporin antibiotic that is no longer commonly used.
Approved
Matched Synonyms: … 7-(D-2-Amino-2-phenylacetamido)-3-acetoxymethyl-delta(sup3)-cephem-4-carboxylic acid …
Matched Iupac: … -[(acetyloxy)methyl]-7-[(2R)-2-amino-2-phenylacetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic …

Thimerosal

Thiomersal (INN), commonly known in the U.S. as thimerosal, is an organomercury compound. This compound is a well-established and widely used antiseptic and antifungal agent. Developed in 1927, thimerosal has been and is still being used as a preservative in some cosmetics, topical pharmaceuticals, and biological drug products, which includes...
Approved
Matched Synonyms: … [(o-carboxyphenyl)thio]ethylmercury sodium salt …
Matched Iupac: … sodium [(2-carboxylatophenyl)sulfanyl](ethyl)mercury …

Dihydroergotamine

A 9,10alpha-dihydro derivative of ergotamine. Dihydroergotamine is used as an abortive therapy for migraines. Its use has largely been supplanted by triptans in current therapy due to the class's greater selectivity and more favourable side effect profile. Recent improvements have been made in the design of intranasal delivery devices allowing...
Approved
Investigational
Matched Synonyms: … 7.3.0.02,6]dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.02,7.012,16]hexadeca-1(16),9,12,14-tetraene-4-carboxamide …
Matched Iupac: … dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),9,12,14-tetraene-4-carboxamide …
Matched Categories: … Cardiovascular Agents …

Alprostadil

Alprostadil is a chemically-identical synthetic form of prostaglandin E1 (PGE1), a potent vasodilator produced endogenously. In 1996, the FDA approved the use of alprostadil, administered either with an intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and it is used in men for whom oral treatment...
Approved
Investigational
Matched International brands: … Cardiobron …
Matched Categories: … Cardiac Therapy ... Cardiovascular Agents ... Cardiovascular System …
Matched Products: … CARDIOBRON …

Somatrogon

Somatrogon is a long-acting recombinant human growth hormone. Growth hormone is a peptide hormone secreted by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and adolescence and regulating metabolic function in adulthood. Recombinant growth hormone therapy for growth hormone deficiency and other conditions has...
Approved
Matched Synonyms: … HUMAN GROWTH HORMONE-CARBOXY-TERMINAL PEPTIDE (CTP) OF THE BETA CHAIN OF HUMAN CHORIONIC GONADOTROPIN …
Matched Description: … It is a chimeric product generated by fusing three copies of the C-terminal peptide (CTP), or 28 carboxy-terminal …

Ferrous sulfate anhydrous

Iron deficiency anemia is a large public health concern worldwide, especially in young children, infants, and women of childbearing age. This type of anemia occurs when iron intake, iron stores, and iron loss do not adequately support the formation of erythrocytes, also known as red blood cells. Ferrous sulfate is...
Approved
Matched International brands: … Caron …

Sodium chlorite

Used as an agent for cleaning drinking water. It is also used as an additive in products like toothpaste and mouthwash. Acidified sodium chlorite was approved by the U.S. Food and Drug Administration as of 2004, as an anti-microbial agent which is non-toxic, but not as a drug [A174811, L5413].
Experimental
Matched Products: … NARYN CARE Stick ... Guard Special Car Edition ... Guard Special Car Edition Refill Stick …

BB 21217

BB 21217 is an anti-BCMA CAR T cell therapy that uses the same CAR molecule as idecabtagene vicleucel (bb2121), but adds the PI3K inhibitor bb007 during ex vivo culture to enrich the drug product (DP) for memory-like T cells.
Investigational
Matched Description: … BB 21217 is an anti-BCMA CAR T cell therapy that uses the same CAR molecule as [idecabtagene vicleucel …

NKX101

NKX101 is an investigational allogeneic chimeric antigen receptor (CAR)-natural killer cell therapy.
Investigational
Matched Description: … NKX101 is an investigational allogeneic chimeric antigen receptor (CAR)-natural killer cell therapy. …

CT041

CT041 is an autologous CAR T-cell product candidate against protein Claudin18.2 (CLDN18.2).
Investigational
Matched Description: … CT041 is an autologous CAR T-cell product candidate against protein Claudin18.2 (CLDN18.2). …

BG1805

BG1805 is an investigational anti-CLL1 chimeric antigen receptor (CAR) T-cell therapy.
Investigational
Matched Description: … BG1805 is an investigational anti-CLL1 chimeric antigen receptor (CAR) T-cell therapy. …

Obecabtagene autoleucel

Obecabtagene autoleucel is an investigational autologous CD19 CAR T cell therapy.
Investigational
Matched Description: … Obecabtagene autoleucel is an investigational autologous CD19 CAR T cell therapy. …

AMG-119

AMG-119 are CAR-T cells targeting delta-like ligand 3 (DLL3).
Investigational
Matched Description: … AMG-119 are CAR-T cells targeting delta-like ligand 3 (DLL3).[A254811] …

Rimiducid

Rimiducid is a lipid-permeable tacrolimus analogue and a protein dimerizer. It was designed to overcome limitations of current cellular immunotherapies used for cancer and other blood disorders by enhancing the control of the immune cell activity and function. When administered via chemically-inducible dimerization (CID) technologies, rimiducid binds to switch proteins...
Investigational
Matched Iupac: … )butanoyl]piperidine-2-carboxylate ... ]propyl]phenoxy}acetamido)ethyl]carbamoyl}methoxy)phenyl]propyl (2S)-1-[(2S)-2-(3,4,5-trimethoxyphenyl ... (2-{3-[(1R)-3-(3,4-dimethoxyphenyl)-1-[(2S)-1-[(2S)-2-(3,4,5-trimethoxyphenyl)butanoyl]piperidine-2-carbonyloxy …

CT120

CT120 is an investigational autologous CD19/22 targeted CAR-T cell immunotherapy.
Investigational
Matched Description: … CT120 is an investigational autologous CD19/22 targeted CAR-T cell immunotherapy. …

PA3-17

PA3-17 is CD7-directed chimeric antigen receptor (CAR) T-cell therapy.
Investigational
Matched Description: … PA3-17 is CD7-directed chimeric antigen receptor (CAR) T-cell therapy. …

CTB001

CTB001 is an anti-claudin 18.2 autologous chimeric antigen receptor (CAR) T-cell therapy under investigation for the treatment of gastric cancers.
Investigational
Matched Description: … CTB001 is an anti-claudin 18.2 autologous chimeric antigen receptor (CAR) T-cell therapy under investigation …

PHE885

PHE885 is an investigational, autologous B-cell Maturation Antigen (BCMA)-directed chimeric antigen receptor (CAR)-T cell therapy.
Investigational
Matched Description: … an investigational, autologous B-cell Maturation Antigen (BCMA)-directed chimeric antigen receptor (CAR …

BRG01

BRG01 is a genetically modified autologous CAR-T cell therapy under investigation for the treatment of nasopharyngeal carcinoma.
Investigational
Matched Description: … nasopharyngeal carcinoma. ... BRG01 is a genetically modified autologous CAR-T cell therapy under investigation for the treatment of …

CB-010

CB-010 is a CRISPR-edited allogeneic CAR-T cell therapy targeting CD19. It is being investigated for the treatment of follicular lymphoma.
Investigational
Matched Description: … CB-010 is a CRISPR-edited allogeneic CAR-T cell therapy targeting CD19. …

KITE-585

KITE-585 is an autologous, fully-human anti-B cell maturation antigen (BCMA) chimeric antigen receptor (CAR) T cell therapy. It is being investigated in the treatment of multiple myeloma.
Investigational
Matched Description: … -585 is an autologous, fully-human anti-B cell maturation antigen (BCMA) chimeric antigen receptor (CAR …
Displaying drugs 1026 - 1050 of 1345 in total